Portable venous indwelling needle dialyzer and intelligent management system thereof

Abstract

The invention relates to the technical field of medical instruments, and discloses a portable venous indwelling needle dialyzer and an intelligent management system thereof.The dialyzer comprises a multi-cavity venous indwelling needle with a blood flow compliance structure, a portable host integrating a blood driving pump and a safety device, a sensor set and an artificial intelligence processor; the intelligent management system comprises a data acquisition unit, an artificial intelligence processing unit and a control instruction output unit. A blood purification core component and a multifunctional module are integrated in a portable host, a vascular access is established by using a multi-cavity indwelling needle, and a closed-loop feedback system is constructed in combination with an in-situ sensor and an AI processor to dynamically regulate and control treatment parameters, so that safe and portable personalized blood purification and multi-mode targeted treatment are realized; the active safety of treatment and the living quality of a patient are improved, and the problems that traditional dialysis depends on large equipment, the function is single, and the intelligent degree is low are solved.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and in particular to a portable intravenous needle dialyzer and an intelligent management system thereof. Background Art

[0002] Blood purification is an important medical technology. It draws the patient's blood out of the body through extracorporeal circulation, removes certain metabolic wastes, toxins or excess water in the blood through a specific purification device, and then returns the purified blood to the body. This technology is currently a key means of treating diseases such as acute and chronic renal failure and replacing kidney function. It plays an irreplaceable role in maintaining the patient's life and improving their quality of life.

[0003] The most widely used blood purification method in clinical practice is hemodialysis, which is usually performed in hospitals or specialized dialysis centers. This technical solution generally requires a surgical procedure to pre-establish an arteriovenous fistula in the patient's arm as a long-term stable vascular access. During treatment, the patient's blood is drawn out of the fistula through a professional, large-scale fixed hemodialysis machine, flows through the dialyzer, and exchanges substances with the dialysate to remove toxins. After purification, the blood is returned to the body. The entire process needs to be monitored and operated by professional medical staff.

[0004] However, due to the high reliance of existing hemodialysis technology on large and complex fixed equipment, as well as the strict requirements for professional medical staff operation and specific medical environment, it has inherent limitations. On the one hand, patients' treatment is greatly restricted in time and space, and they must travel back and forth to medical institutions regularly, which seriously affects their normal life, work and social life, and greatly reduces their quality of life. On the other hand, traditional treatment plans are usually based on preset parameters and lack a dynamic response mechanism to the real-time physiological changes of individual patients. When faced with acute complications such as hypotension during dialysis, manual intervention often lags, posing potential risks to the safety of the treatment process. At the same time, the functions of existing equipment are relatively single, mainly focusing on toxin removal, and it is difficult to meet more complex and personalized clinical treatment needs such as lipid regulation and targeted drug delivery. Summary of the Invention

[0005] In view of the shortcomings of the existing technology, the present invention provides a portable intravenous needle dialyzer and its intelligent management system, aiming to solve the problems of poor portability, low intelligence and single function of the existing blood purification technology.

[0006] To achieve the above objectives, the present invention is implemented through the following technical solutions: A portable intravenous needle dialyzer, comprising: A multi-cavity venous indwelling needle having a structure that conforms to the direction of venous blood flow to reduce the recirculation rate; a portable host connected to the multi-cavity venous catheter, the portable host integrating a blood drive pump, a dialyzer / filter, and a safety device, the safety device including at least one of an ultrasonic bubble detector and an optical blood leakage detector; a sensor group, disposed at at least one of the multi-cavity venous indwelling needle and the portable host, for real-time monitoring of blood parameters; an artificial intelligence processor, electrically connected to the sensor group and the portable host, for controlling the operation of the portable intravenous needle dialyzer according to the blood parameters; A display panel is connected to the artificial intelligence processor and is used to display information.

[0007] Preferably, the blood flow-compliant structure of the multi-cavity venous indwelling needle is as follows: The multi-lumen venous indwelling needle includes a blood drawing cavity and a reinfusion cavity, wherein the inlet of the blood drawing cavity is located at the distal end of the catheter, and the outlet of the reinfusion cavity is located at the proximal end of the catheter; The multi-cavity venous indwelling needle further comprises at least one of the following cavities: Medication / nutrition cavity, ultrasound guidewire cavity.

[0008] Preferably, the portable host further integrates at least one of the following components: A multifunctional blood purification module, which is implemented by an adsorption column and is at least one of a blood lipid removal module, a blood glucose regulation module, a toxin removal module, an iron overload treatment module, and an acid dissolution / alkalinization module; A microinjection pump is connected to the drug administration / nutrient lumen of the multi-lumen venous indwelling needle.

[0009] Preferably, the portable host is further integrated with an ultrasonic intervention module, which includes a micro piezoelectric ceramic ultrasonic generator, and its energy is conducted in at least one of the following ways: a miniature ultrasound probe guidewire placed in the ultrasound guidewire cavity; Externally applied transducer.

[0010] Preferably, the sensor group includes at least one of the following sensors: Multi-wavelength biophotonic sensors, micro radar detectors, integrated pressure sensors, and electrochemical sensors.

[0011] Preferably, the artificial intelligence processor is configured to operate the portable intravenous needle dialyzer in at least one of the following modes: Whole-body hemodialysis / healthcare mode, single-vessel targeting mode, and double-vessel targeting mode.

[0012] A portable intravenous needle dialyzer intelligent management system, comprising: Data acquisition unit, used to receive real-time blood parameters and equipment operation data; an artificial intelligence processing unit, connected to the data acquisition unit, and configured to analyze the real-time blood parameters and the device operation data to dynamically generate treatment parameters and predict the risk of treatment complications; A control instruction output unit is connected to the artificial intelligence processing unit and is configured to output a control instruction for controlling the operation of the portable intravenous needle dialyzer according to the treatment parameters and the complication risk.

[0013] Preferably, the control instruction is used to control the working state of at least one of the following functions: a multifunctional blood purification function and an ultrasonic intervention function.

[0014] Preferably, the risk of treatment complications predicted by the artificial intelligence processing unit is the risk of hypotension during dialysis; when the artificial intelligence processing unit predicts the risk of hypotension during dialysis, the control instruction output unit outputs an intervention instruction for automatically reducing the ultrafiltration rate or increasing fluid infusion.

[0015] Preferably, the artificial intelligence processing unit is further configured to generate a blood quality assessment report and healthcare recommendations based on the real-time blood parameters and the device operation data, and output the blood quality assessment report and the healthcare recommendations for display.

[0016] The present invention provides a portable intravenous needle dialyzer and its intelligent management system. It has the following beneficial effects: 1. The present invention miniaturizes the dialysis system and integrates it into a portable host, which is connected to the human body through a multi-cavity venous catheter. It not only provides patients with end-stage renal disease with the possibility of home or mobile treatment, but also allows for convenient blood purification health care at conventional infusion sites. Compared with existing technologies, it greatly improves the flexibility and accessibility of applications and solves the problem of patients having to travel back and forth to medical institutions and rigid treatment methods.

[0017] 2. The present invention introduces a closed-loop feedback system consisting of an artificial intelligence processor and an in-situ sensor group. The system can dynamically adjust the treatment plan based on real-time monitored blood parameters. This changes the traditional dialysis treatment model that relies on fixed parameters and delayed manual intervention. This design helps to proactively avoid the risks of common complications such as hypotension during treatment, and improves the safety and personalization level of the entire treatment process.

[0018] 3. The present invention reserves and integrates interfaces for multiple functional modules in a portable host, such as an adsorption column, a microinjection pump, and an ultrasonic intervention module. This integrated platform can realize multiple blood treatment functions on a single device. Compared with the current situation in which different treatments (such as dialysis, blood lipid adsorption, and targeted drug delivery) need to be completed by different independent devices, it helps to solve the problem of single treatment function and difficulty in implementing multi-method coordinated treatment.

[0019] 4. Through the artificial intelligence processor configured in the present invention, the portable intravenous needle dialyzer can perform single-vessel or dual-vessel targeted treatment mode. This solution can establish local extracorporeal circulation for specific organs, achieving efficient perfusion and immediate clearance of drugs. It overcomes to a certain extent the inherent defects of traditional systemic medication, such as low target drug concentration and large systemic side effects, and provides a new technical approach to improve local treatment effects and reduce systemic toxic and side effects. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 This is a schematic diagram of the overall system of the portable intravenous needle dialyzer of the present invention; Figure 2 This is a detailed diagram of the structure of a multi-cavity venous catheter; Figure 3 This is a schematic diagram of the tip of a multi-lumen indwelling needle working in a vein; Figure 4 This is the workflow diagram of the AI ​​intelligent management system; Figure 5 Schematic diagram of targeted organ dialysis mode.

[0021] Among them, 1. Multi-cavity venous catheter; 2. Portable host; 11. Blood drawing cavity; 12. Infusion cavity; 13. Drug administration / nutrition cavity; 14. Ultrasonic guidewire cavity; 18. Sensor group; 21. Blood drive pump; 23. Dialyzer / filter; 24. Adsorption column; 26. Microinjection pump; 27. Miniature piezoelectric ceramic ultrasonic generator; 28. Externally applied transducer; 29. ​​Display panel; 141. Miniature ultrasound probe guidewire; 181. Multi-wavelength biophotonic sensor; 182. Miniature radar detector; 183. Integrated pressure sensor; 184. Electrochemical sensor; 210. Ultrasonic bubble detector; 211. Optical blood leakage detector. DETAILED DESCRIPTION

[0022] The following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the drawings in the present specification. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0023] Please see the attached Figure 1 -Attached Figure 5 The present invention provides a portable intravenous needle dialyzer and its intelligent management system. The system aims to achieve efficient, safe, and personalized extracorporeal blood purification and treatment through integrated hardware design and intelligent control algorithms.

[0024] In an exemplary embodiment, a portable intravenous needle dialyzer comprises a multi-cavity intravenous needle (1) and a portable host (2), wherein the multi-cavity intravenous needle (1) and the portable host (2) are detachably connected to form a complete blood circulation and treatment circuit.

[0025] The multi-cavity venous indwelling needle (1) is a key blood interface component and has a structure that conforms to the direction of venous blood flow to reduce the recirculation rate.

[0026] The multi-cavity venous indwelling needle (1) comprises a catheter body, in which a plurality of mutually independent cavities are arranged.

[0027] In order to achieve effective blood extraction and reinfusion, the multi-cavity venous indwelling needle (1) includes a blood extraction cavity (11) and a reinfusion cavity (12).

[0028] The inlet of the blood extraction chamber (11) is preferably arranged at the distal end of the catheter, while the outlet of the reinfusion chamber (12) is arranged at the proximal end of the catheter. This spatial layout conforms to the direction of venous blood return and can significantly reduce the probability of purified blood being re-aspirated.

[0029] Furthermore, the multi-cavity venous catheter (1) may also include at least one of a drug administration / nutrition cavity (13) and an ultrasound guidewire cavity (14). These additional cavities provide a physical channel for achieving multifunctional treatment (such as simultaneous drug administration and ultrasound intervention).

[0030] The portable host (2) is the core processing unit of the present invention, and is internally integrated with a blood drive pump (21), such as a peristaltic pump, for providing power for blood circulation in the extracorporeal space. The portable host (2) also includes a dialyzer / filter (23) for performing basic solute exchange and water removal.

[0031] In order to ensure the safety of operation, a safety device is integrated into the portable host (2), which exemplarily includes at least one of an ultrasonic bubble detector (210) and an optical blood leakage detector (211), and is used to monitor and eliminate potential risks before blood is transfused.

[0032] An important feature of the present invention is its in-situ monitoring capability. The sensor group (18) is configured in the catheter of the multi-cavity venous indwelling needle (1) or the pipeline of the portable host (2). The sensor group (18) can monitor various physiological and biochemical parameters of the blood flowing through in real time.

[0033] Specifically, the sensor group (18) may include at least one of a multi-wavelength biophotonic sensor (181), a micro radar detector (182), an integrated pressure sensor (183), and an electrochemical sensor (184), which are respectively used to monitor key indicators such as blood oxygen, blood flow, pressure, pH value, blood sugar, electrolytes, etc.

[0034] The operation of all hardware components is coordinated and controlled by a built-in artificial intelligence (AI) processor.

[0035] The artificial intelligence (AI) processor is electrically connected to the sensor group (18) and various functional modules in the portable host (2). At the same time, the portable host (2) is also provided with a display panel (29) for human-computer interaction.

[0036] The following describes the collaborative working mode of the device and system of the present invention through several specific embodiments.

[0037] Example 1: Whole-body blood health care and dynamic ultrafiltration control Based on the regular blood care and dynamic ultrafiltration control of peripheral veins, in this embodiment, the present invention mainly reflects its health care function. The user does not need to perform complicated vascular access surgery. Just like conventional intravenous infusion (drip bottle), the multi-cavity venous catheter (1) is inserted into the peripheral vein of the arm and other parts. After the artificial intelligence (AI) processor is started, the whole body blood care mode is executed.

[0038] This model aims to regularly remove metabolic waste, inflammatory factors or potentially harmful substances that have accumulated in the body and are still at subclinical levels, so as to prevent diseases and maintain the body's health. It aims to regularly remove metabolic waste, inflammatory factors or potentially harmful substances that have accumulated in the body and are still at subclinical levels, so as to prevent diseases and maintain the body's health.

[0039] Blood is drawn from the blood drawing chamber (11) and flows sequentially through the blood drive pump (21) and the dialyzer / filter (23) in the portable host (2).

[0040] Furthermore, a multifunctional blood purification module may be integrated into the portable host (2), which is implemented by an adsorption column (24). For example, a blood lipid removal module may be used to deeply purify the blood, and the purified blood is returned to the body via the reinfusion cavity (12).

[0041] During this process, the artificial intelligence (AI) processor, as the data acquisition and processing unit of the intelligent management system, continuously receives real-time blood parameters including blood pressure from the sensor group (18) and analyzes them in combination with the equipment operation data. One of its core tasks is to dynamically generate treatment parameters to predict and avoid the risk of complications such as hypotension during dialysis.

[0042] Ultrafiltration rate The dynamic adjustment of can be achieved through the following model: ; Where, for The instantaneous ultrafiltration rate at time is the basic ultrafiltration rate, is the proportional control coefficient, for The real-time error at the moment, is the integral control coefficient, is the integration variable.

[0043] When a downward trend in blood pressure is detected, the processing unit immediately calculates and outputs a control instruction, and reduces the ultrafiltration rate through the control instruction output unit, thereby achieving stable control of blood pressure. After the treatment is completed, the AI ​​processing unit can also generate a blood quality assessment report and health care recommendations, and present them through the display panel (29).

[0044] Example 2: Single-vessel targeted cerebral infarction prevention and ultrasound intervention In this embodiment, for patients with a high risk of thrombosis, a multi-cavity venous catheter (1) is placed in the internal jugular vein, the system operates in a single-vessel targeting mode, and the multi-cavity venous catheter (1) needs to include an ultrasound guidewire cavity (14).

[0045] An ultrasonic intervention module is integrated in the portable host (2). The module includes a micro piezoelectric ceramic ultrasonic generator (27), and the ultrasonic energy generated by the generator can be conducted in at least one manner.

[0046] One way is that when precise intervention is required inside a blood vessel, energy can be precisely conducted through a miniature ultrasound probe guidewire (141) placed in an ultrasound guidewire cavity (14) of a multi-cavity venous catheter (1).

[0047] As another or supplementary embodiment, energy can also be conducted through an externally applied transducer (28), which can be directly applied to the surface of the patient's neck to perform non-invasive energy intervention on the target blood vessels below.

[0048] The artificial intelligence (AI) processor continuously monitors microthrombosis markers by analyzing data from a sensor group (18) (such as a micro radar detector (182)). Once an increased risk of thrombosis is predicted, the intelligent management system outputs control instructions.

[0049] The control instruction is used to control the working state of the ultrasound intervention function, that is, to start the ultrasound intervention module, and perform low-energy ultrasound treatment on key positions such as the jugular sinus through the aforementioned micro-ultrasound probe guide wire (141) or the external applied transducer (28). At the same time, it can also be linked to the micro-injection pump (26) to accurately infuse anticoagulant drugs through the drug administration / nutrition cavity (13).

[0050] Example 3: Dual-vessel targeted liver therapy This embodiment is mainly used for targeted chemotherapy of local tumors, and the system operates in a dual-vessel targeting mode. Two sets of the device of the present invention or a specially designed multi-cavity venous indwelling needle (1) with arterial and venous access are required.

[0051] One needle is placed in the hepatic artery and another in the hepatic vein to establish extracorporeal circulation, and an artificial intelligence (AI) processor executes a preset targeted treatment program.

[0052] The control instruction output unit issues an instruction to control the microinjection pump (26) connected to the drug administration / nutrient chamber (13) to inject high-concentration chemotherapy drugs from the hepatic artery end.

[0053] At the same time, the control instructions control the multifunctional blood purification module (e.g., an adsorption column (24) equipped with a specific drug adsorbent) located in the portable host (2) to run at full speed, quickly purify the blood drawn from the hepatic vein, remove the residual chemotherapy drugs therein, and then return the clean blood to the systemic circulation.

[0054] Through the above-mentioned approach, the integrated, intelligent system provided by the present invention can flexibly combine its hardware functions according to different clinical needs, and under the precise control of the AI ​​processor, it can achieve personalized and efficient treatment and health care tasks that are difficult to complete with traditional equipment, and has significant clinical application value.

[0055] While embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions, and variations may be made to these embodiments without departing from the principles and spirit of the invention, and that the scope of the invention is defined by the appended claims and their equivalents.

Claims

1. A portable intravenous needle dialyzer, characterized in that: include: A multi-cavity venous indwelling needle (1), wherein the multi-cavity venous indwelling needle (1) has a structure that conforms to the direction of venous blood flow to reduce the recirculation rate; A portable host (2) connected to the multi-cavity venous indwelling needle (1), wherein the portable host (2) is integrated with a blood drive pump (21), a dialyzer / filter (23), and a safety device, wherein the safety device includes at least one of an ultrasonic bubble detector (210) and an optical blood leakage detector (211); A sensor group (18) is arranged at at least one of the multi-cavity venous indwelling needle (1) and the portable host (2) for real-time monitoring of blood parameters; an artificial intelligence (AI) processor electrically connected to the sensor group (18) and the portable host (2) for controlling the operation of the portable intravenous needle dialyzer according to the blood parameters; A display panel (29) is connected to the artificial intelligence (AI) processor and is used to display information.

2. The portable intravenous needle dialyzer according to claim 1, characterized in that: The blood flow-compliant structure of the multi-cavity venous indwelling needle (1) is as follows: The multi-lumen venous indwelling needle (1) comprises a blood drawing cavity (11) and a reinfusion cavity (12), wherein the inlet of the blood drawing cavity (11) is located at the distal end of the catheter, and the outlet of the reinfusion cavity (12) is located at the proximal end of the catheter; The multi-cavity venous indwelling needle (1) further comprises at least one of the following cavities: Drug administration / nutrition cavity (13), ultrasound guidewire cavity (14).

3. The portable intravenous needle dialyzer according to claim 1, characterized in that: The portable host (2) further integrates at least one of the following components: A multifunctional blood purification module, wherein the multifunctional blood purification module is realized by an adsorption column (24), and the multifunctional blood purification module is at least one of a blood lipid removal module, a blood sugar regulation module, a toxin removal module, an iron overload treatment module, and an acid dissolution / alkalinization module; A microinjection pump (26) is connected to the drug administration / nutrient cavity (13) of the multi-cavity venous indwelling needle (1).

4. The portable intravenous needle dialyzer according to claim 2, characterized in that: The portable host (2) is also integrated with an ultrasonic intervention module, which includes a micro piezoelectric ceramic ultrasonic generator (27), and its energy is conducted in at least one of the following ways: A miniature ultrasonic probe guidewire (141) placed in the ultrasonic guidewire cavity (14); Externally applied transducer (28).

5. The portable intravenous needle dialyzer according to claim 1, characterized in that: The sensor group (18) includes at least one of the following sensors: Multi-wavelength biophotonic sensors (181), micro radar detectors (182), integrated pressure sensors (183), and electrochemical sensors (184).

6. The portable intravenous needle dialyzer according to claim 1, characterized in that: The artificial intelligence (AI) processor is configured to cause the portable intravenous needle dialyzer to operate in at least one of the following modes: Whole-body hemodialysis / healthcare mode, single-vessel targeting mode, and double-vessel targeting mode.

7. A portable intravenous catheter dialyzer intelligent management system, applied to a portable intravenous catheter dialyzer according to any one of claims 1 to 6, characterized in that: include: Data acquisition unit, used to receive real-time blood parameters and equipment operation data; an artificial intelligence (AI) processing unit, connected to the data acquisition unit, and configured to analyze the real-time blood parameters and the device operation data to dynamically generate treatment parameters and predict the risk of treatment complications; A control instruction output unit is connected to the artificial intelligence (AI) processing unit and is configured to output a control instruction for controlling the operation of the portable intravenous needle dialyzer according to the treatment parameters and the complication risk.

8. The portable intravenous needle dialyzer intelligent management system according to claim 7, characterized in that: The control instruction is used to control the working state of at least one of the following functions: a multifunctional blood purification function and an ultrasonic intervention function.

9. The portable intravenous catheter dialyzer intelligent management system according to claim 7, characterized in that: The risk of treatment complications predicted by the artificial intelligence (AI) processing unit is the risk of hypotension during dialysis; when the artificial intelligence (AI) processing unit predicts the risk of hypotension during dialysis, the control instruction output unit outputs an intervention instruction for automatically reducing the ultrafiltration rate or increasing fluid infusion.

10. The portable intravenous needle dialyzer intelligent management system according to claim 7, characterized in that: The artificial intelligence (AI) processing unit is further configured to generate a blood quality assessment report and healthcare recommendations based on the real-time blood parameters and the device operation data, and output the blood quality assessment report and the healthcare recommendations for display.

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