Individualized water bag-dosimetry multimode oral cavity fixing device for radiotherapy
By designing a multi-mode oral fixation device that includes a mouthpiece and an expansion element, the problems of poor position repeatability and high cost in the prior art are solved, enabling real in vivo dose measurement, improving the accuracy and safety of radiotherapy, and making it suitable for individualized water bag-dose determination in radiotherapy.
Patent Information
- Application Number
- CN202511503547.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-10-21
- Publication Date
- 2025-11-18
AI Technical Summary
Existing oral fixation devices have problems such as poor position repeatability, high cost and inability to measure dose in radiotherapy. Traditional mouthpieces have large differences between finished products, 3D printing mouthpieces are complicated and difficult to mass-produce, MR and CBCT cannot accurately provide electron density values, and traditional mouthpieces cannot reproduce the true in vivo dose.
Design a multi-mode oral fixation device including a mouthpiece and an expansion element. The mouthpiece contacts the back of the tongue and has a breathing channel and an occlusal part. The expansion element fits the hard palate and is equipped with a dose detection element such as a thermoluminescent dosimeter for measuring the irradiation dose on the tongue surface. The device has a simple structure, low cost, and is easy to mass-produce.
It achieves repeatability and precision in oral cavity positioning, measures real-life dose, reduces manufacturing costs, facilitates mass production, reduces errors between planning and execution, and improves the accuracy and safety of radiotherapy.
Smart Images
Figure CN120960663A_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The present application relates to the technical field of radiotherapy mouthpiece, in particular to a personalized water sac-dose measuring multi-mode oral cavity fixing device for radiotherapy. BACKGROUND
[0002] The oral cavity fixing device, also known as a mouthpiece, can stabilize the oral cavity and head and neck position of a patient during radiotherapy (such as nasopharyngeal carcinoma and oral cavity cancer radiotherapy), reduce displacement caused by swallowing, breathing and other actions during treatment, ensure accurate irradiation of the target area by the rays, and reduce the risk of normal tissue damage.
[0003] The existing mouthpiece mainly emphasizes its fixing effect on the patient's position. The most commonly used method is as follows: a syringe is selected according to the size of the patient's oral cavity. A 20 mL disposable syringe is generally used for adults, and a 10 mL disposable syringe is used for children. The needle plug of the syringe is pulled out and discarded. Then, a disposable surgical knife is used to cut the needle cylinder part 3 cm from the needle tip. The needle tip is discarded, and the cylinder end is wrapped with adhesive tape for sterilization and standby. When the patient is positioned for radiotherapy, the prepared mouthpiece cylinder head is placed inside the oral cavity with the tail flat placed on the upper and lower lips.
[0004] The relatively complex and less common personalized 3D printed mouthpiece is used as follows: first, the patient's oral cavity anatomical data is obtained through oral CT scanning, a personalized three-dimensional model is designed with the help of professional software, and biocompatible materials (such as ABS resin and degradable materials) are selected for 3D printing, polishing and sterilization.
[0005] However, in the prior art, the syringe type mouthpiece is usually manually made, and the finished products have large differences. The surface of the finished product is smooth, and there is no specific biting position. The position repeatability is poor in actual use. Moreover, although the 3D printed mouthpiece can achieve individual customization, the steps are complex, the production time is long, the cost is high, and it is difficult to be used in clinical use in batches.
[0006] Intensity-Modulated Radiation Therapy (IMRT): is a high-precision radiotherapy technique that uses a multi-leaf collimator of a linear accelerator controlled by a computer to divide the irradiation field into multiple small sub-fields, and accurately adjusts the intensity of each sub-field according to the shape of the tumor target area and the distribution of the surrounding normal tissues.
[0007] Adaptive Radiation Therapy (ART): It is based on IMRT, through the use of imaging technology (CT / MR / CBCT) to monitor the changes of patient's anatomic structure (such as tumor size, position change, etc.) during treatment, re-evaluate the dose distribution and dynamically adjust the treatment plan to ensure the target area to obtain accurate dose, while reducing the damage to normal tissues, especially suitable for treating anatomic changeable tumors, and improving the individualization and precision of radiotherapy.
[0008] MR and CBCT: Magnetic resonance imaging and cone beam CT, which are the ways of ART radiotherapy to obtain real-time images of patients. Neither of the two methods can accurately provide electron density (ED) values required for dose calculation of radiotherapy plan.
[0009] sCT: Synthetic CT is an image with CT-like tissue density information generated by non-CT images (such as MRI, CBCT) or other data combined with algorithms, commonly used for ART dose calculation and dose reconstruction.
[0010] At the same time, the traditional mouthpiece also does not have the function of measuring dose, so that the real in vivo dose cannot be restored during radiotherapy. SUMMARY
[0011] The purpose of the present application is to provide a radiotherapy individualized water bag-dose measuring multi-mode oral cavity fixing device to solve the above-mentioned problems existing in the prior art, which has simple structure, low cost and can restore the real in vivo dose.
[0012] To achieve the above-mentioned purpose, the present application provides the following scheme: The present application provides a radiotherapy individualized water bag-dose measuring multi-mode oral cavity fixing device, comprising a mouthpiece and an expansion element, the mouthpiece is used to be placed in the oral cavity of the patient, and the bottom surface of the mouthpiece is used to contact the dorsum of the tongue of the patient, a breathing channel is arranged on the mouthpiece, the breathing channel penetrates through the mouthpiece in the length direction of the mouthpiece, one end of the mouthpiece is provided with a bite part, the bite part is used for the patient to bite, and the bite part is filled with an oral impression material, the expansion element is located at the outer periphery of the mouthpiece, and the expansion element is detachably connected with the mouthpiece, the expansion element is used to fit the hard palate of the patient, and a dose detection element is further arranged on the mouthpiece, the dose detection element is used to detect the irradiation dose received by the patient's tongue surface.
[0013] Preferably, the mouthpiece comprises a tongue depressor and a body element integrally formed on the upper surface of the tongue depressor, the lower surface of the tongue depressor is used to contact the dorsum of the tongue of the patient, and both sides of the tongue depressor extend beyond the two sides of the body element, the dose detection element is mounted on the tongue depressor away from the body element, one end of the body element is flush with the tongue depressor, the other end of the body element is provided with the bite portion, and the bite portion extends beyond the tongue depressor, and the breathing passage is provided on the body element.
[0014] Preferably, the dose detection element is detachably connected to the tongue depressor, or the dose detection element is encapsulated in the tongue depressor.
[0015] Preferably, the tongue depressor is semi-elliptical, and the front end of the tongue depressor is an arc-shaped curved surface, the front end of the tongue depressor is used to fit the mandibular alveolar ridge of the patient, and the rear end of the tongue depressor is a flat surface, the rear end of the tongue depressor is used to align the line between the second molars on both sides of the patient or the line between the third molars on both sides of the patient.
[0016] Preferably, the dose detection element comprises a plurality of thermoluminescence dosimeters, and the plurality of thermoluminescence dosimeters are uniformly arranged on both sides of the body element.
[0017] Preferably, the cross section of the body element and the cross section of the breathing passage are both isosceles trapezoidal, and the upper base of the isosceles trapezoid is close to the hard palate of the patient, and the lower base of the isosceles trapezoid is close to the dorsum of the tongue of the patient.
[0018] Preferably, the upper surface of the bite portion and the lower surface of the bite portion are both provided with a concave curved surface, and the concave curved surface is used to fill the mouth impression material.
[0019] Preferably, the expansion element is a water bag, the water bag is provided with a water injection hole, the water injection hole is closed using a heparin cap, and is used in cooperation with a disposable syringe, one side of the water bag used to contact the mouthpiece is made of hard material, and the shape of the side of the water bag used to contact the mouthpiece corresponds to the shape of the mouthpiece, the other side of the water bag is made of elastic material and is used to fit the hard palate of the patient.
[0020] Preferably, the water bag is divided into a full-mouth water bag or a half-mouth water bag, the full-mouth water bag covers the top surface and both sides of the mouthpiece, the half-mouth water bag covers one side and part of the top surface of the mouthpiece, and the water bag is used to fill water or a contrast agent aqueous solution.
[0021] Preferably, each of the two outer sidewalls of the mouthpiece is provided with at least one guide groove, one end of the guide groove extends to the upper end of the mouthpiece, and the other end of the guide groove extends to the lower end of the mouthpiece. The water bag is provided with a guide block on the side for contacting the mouthpiece. The number of guide grooves and guide blocks are the same and their positions correspond one-to-one. The water bag can be inserted from above the mouthpiece downwards to the outer periphery of the mouthpiece, and the guide block slides from top to bottom into the guide groove. Both the guide groove and the guide block are dovetail-shaped.
[0022] The present invention achieves the following technical effects compared to the prior art: This invention provides a personalized water-filled balloon-dosage measurement multimodal oral fixation device for radiotherapy, comprising a mouthpiece and an expansion element. The mouthpiece is placed inside the patient's oral cavity, with its bottom surface contacting the patient's tongue, thereby fixing the patient's oral cavity while protecting normal tissues and improving the accuracy and safety of radiotherapy. The mouthpiece has a breathing channel extending along its length to avoid affecting the patient's normal breathing. One end of the mouthpiece has an occlusal portion for the patient to bite down on, fixing the mouthpiece's position. The occlusal portion is filled with oral impression material to better conform to the patient's teeth, enabling reusability. The expansion element is located on the outer periphery of the mouthpiece and is detachably connected to it. The expansion element conforms to the patient's hard palate, thereby... The combination of the expansion element and the mouthpiece provides support for the patient's hard palate. Quantitative and individualized filling of the expansion element ensures the stability of the oral cavity's void filling. By selecting the filling medium of the expansion element, the visibility or invisibility of the mouthpiece in different imaging modes can be achieved as needed, thereby increasing the modulation space for dose distribution on the oral mucosa surface at the physical level. The design of the expansion element and occlusion further improves the repeatability of the patient's oral position, which is conducive to achieving consistency between the actual dose distribution and the expected dose distribution on the oral mucosa surface. The mouthpiece is also equipped with a dose detection element to detect the irradiation dose received by the patient's tongue surface, thereby realizing the measurement of in vivo dose. This provides a solution for quantifying and reducing the error between planning and execution. Moreover, the overall structure is simple, the manufacturing cost is low, and it is easy to mass-produce. Attached Figure Description
[0023] To more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the drawings used in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.
[0024] Figure 1This is a top view of the mouthpiece in this invention; Figure 2 This is a front view of the mouthpiece in this invention; Figure 3 This is a side view of the mouthpiece in this invention; Figure 4 This is a schematic diagram of the structure of the main body element in this invention; Figure 5 This is a schematic diagram of the combination of the semi-oral bladder and the mouthpiece in this invention; Figure 6 This is a schematic diagram of the combination of the full-mouth water bag and the mouthpiece in this invention; Figure 7 The percentage dose distribution curve for monoenergetic X-rays; Figure 8 This is a commonly used method for pre-treatment dose verification; Figure 9 This is a common cause of the difference between the actual dose and the expected dose during radiotherapy; Figure 10 This is a schematic diagram comparing dose reconstruction with the actual in vivo dose measurement in this invention; In the diagram: 1-tongue depressor, 2-body element, 3-occlusal part, 4-breathing channel, 5-dose detection element, 6-concave curved surface, 7-half-mouth water sac, 8-full-mouth water sac, 9-injection hole, 10-guide groove. Detailed Implementation
[0025] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.
[0026] The purpose of this invention is to provide a personalized water-filled balloon-dose measurement multimodal oral fixation device for radiotherapy, which solves the problems existing in the prior art. It has a simple structure, low cost, and can reproduce the true in vivo dose.
[0027] To make the above-mentioned objects, features and advantages of the present invention more apparent and understandable, the present invention will be further described in detail below with reference to the accompanying drawings and specific embodiments.
[0028] like Figures 1-10As shown, this embodiment provides a personalized water-filled bag-dosage measurement multimodal oral fixation device for radiotherapy, including a mouthpiece and an expansion element. The mouthpiece is placed inside the patient's mouth, with its bottom surface contacting the patient's tongue, thereby fixing the patient's oral cavity while protecting normal tissue, improving the accuracy and safety of radiotherapy. The mouthpiece has a breathing channel 4 that extends through it along its length, thus avoiding interference with the patient's normal breathing. One end of the mouthpiece has an occlusal portion 3 for the patient to bite down on, fixing the mouthpiece's position. The occlusal portion 3 is filled with oral impression material, allowing it to better conform to the patient's teeth and enabling reusability. The expansion element is located on the outer periphery of the mouthpiece and is detachably connected to it. The expansion element conforms to the patient's hard palate. Furthermore, by combining the expansion element and the mouthpiece, support for the patient's hard palate is achieved. The stability of the oral cavity filling is ensured by quantitative and individualized filling of the expansion element. By selecting the filling medium of the expansion element, the visibility or invisibility of the mouthpiece in different imaging modes can be achieved as needed. This increases the modulation space for the dose distribution on the oral mucosa surface at the physical level. The combination of the expansion element and the occlusal part 3 further improves the repeatability of the patient's oral position, which is conducive to achieving consistency between the actual dose distribution and the expected dose distribution on the oral mucosa surface. The mouthpiece is also equipped with a dose detection element 5, which is used to detect the irradiation dose received by the patient's tongue surface, thereby realizing the measurement of in vivo dose. This provides a solution for quantifying and reducing the error between planning and execution. Moreover, the overall structure is simple, the manufacturing cost is low, and it is easy to mass-produce.
[0029] Specifically, the mouthpiece includes a tongue depressor 1 and a body element 2. The body element 2 is integrally formed on the upper surface of the tongue depressor 1. The lower surface of the tongue depressor 1 is used to contact the back of the patient's tongue, thereby pressing down the patient's tongue. Both sides of the tongue depressor 1 extend beyond the sides of the body element 2, which facilitates the installation of expansion elements on the outer periphery of the body element 2. The dose detection element 5 is installed on the tongue depressor 1, avoiding the position of the body element 2. One end of the body element 2 is flush with the tongue depressor 1, and the other end of the body element 2 is provided with a biting part 3, which extends beyond the tongue depressor 1, ensuring that the tongue depressor 1 is positioned corresponding to the patient's tongue and that the patient can successfully bite down on the biting part 3. The breathing channel 4 is opened on the body element 2.
[0030] As a preferred embodiment, both the tongue depressor 1 and the body element 2 are made of rigid materials, such as medical polypropylene and polycarbonate, which are easy to process and have low cost, enabling mass production.
[0031] The dose detection element 5 and the tongue depressor 1 can be detachably connected. When the mouthpiece is replaced, the dose detection element 5 can be reused, or the dose detection element 5 can be encapsulated in the tongue depressor 1, which can achieve stable installation of the dose detection element 5.
[0032] The tongue depressor 1 is semi-elliptical, similar to the shape of the patient's tongue, and the front end of the tongue depressor 1 is an arc-shaped surface. The front end of the tongue depressor 1 is used to fit the patient's mandibular alveolar process. The rear end of the tongue depressor 1 is flat. The rear end of the tongue depressor 1 is used to align with the line connecting the patient's two second molars or the line connecting the patient's two third molars, thereby limiting the position of the tongue depressor 1. Those skilled in the art can also make adaptive adjustments to the placement of the rear end of the tongue depressor 1 according to the actual situation.
[0033] The dose detection element 5 includes multiple thermoluminescent dosimeters (TLDs). As a point dose measurement device, the thermoluminescent dosimeter is suitable for localized, low-cost dose verification. When the thermoluminescent dosimeter is irradiated with ionizing radiation, the radiation energy excites electrons in the material's crystal lattice from their ground state to trap levels in the band gap (formed by crystal defects or dopant ions) and traps them. When the material is heated, the trapped electrons gain energy and release from the traps, returning to their ground state as light—thermoluminescence. The number of released photons has a linear relationship with the radiation dose absorbed by the material within a certain range; the absorbed dose can be calculated by measuring the luminescence intensity.
[0034] Multiple thermoluminescent dosimeters are evenly arranged on both sides of the main body element 2, and the number of thermoluminescent dosimeters can be set as needed. The positions of the dosimeters can be evenly distributed according to the area of the extension sections on both sides of the tongue depressor 1. At the same time, after the patient receives irradiation, the results obtained by the TLD measurement can reflect the actual dose received by the patient's tongue surface. Since the TLD can be reused, the number of readings can be determined as needed. Theoretically, it can be read once after each irradiation to achieve actual dose measurement per minute.
[0035] Both the cross-section of the main body element 2 and the cross-section of the breathing channel 4 are isosceles trapezoids, with the upper base of the isosceles trapezoid close to the patient's hard palate and the lower base of the isosceles trapezoid close to the patient's tongue.
[0036] The occlusal portion 3 is cubic in shape, and both the upper and lower surfaces of the occlusal portion 3 are provided with concave curved surfaces 6, which are used to fill oral impression material. The occlusal portion 3 is also provided with a breathing channel 4.
[0037] The expansion element is a water bladder with an injection hole 9. The injection hole 9 is sealed with a heparin cap and used with a disposable syringe to achieve the function of repeatedly and quantitatively injecting / extracting liquid / gas into the water bladder. The side of the water bladder that contacts the mouthpiece is made of a rigid material and its shape corresponds to the shape of the mouthpiece. The other side of the water bladder is made of an elastic material (such as medical silicone rubber) and is used to fit the patient's hard palate.
[0038] The water bladder is divided into a full-mouth water bladder 8 or a half-mouth water bladder 7. The full-mouth water bladder 8 covers the top and sides of the mouthpiece, while the half-mouth water bladder 7 covers one side and part of the top surface of the mouthpiece. Those skilled in the art can select the appropriate water bladder according to actual needs and utilize the individualized water bladder and occlusal part 3 to adapt to the oral anatomy and occlusal relationship of different patients, filling intraoral gaps to improve the consistency of patient positioning from the planned state to the treatment state. Regarding the design of the water bladder filling volume, a specific volume of liquid or gas can be loaded as needed to fill it, so as to better fit the individualized hard palate shape of the patient and ensure the repeatability of the mouthpiece shape during use.
[0039] The water-filled sac is used to fill with water or contrast agent solutions of varying concentrations to achieve visibility or invisibility of the mouthpiece in different imaging modes as needed. In this embodiment, the design of the water-filled sac only needs to allow for slight differentiation between the sac and surrounding anatomical structures in the image. The liquid filling physically increases the modulation space for dose distribution to the oral mucosa and surrounding organs at risk, while minimizing drastic fluctuations in TLD measurements due to the dose buildup region (e.g., ...). Figure 7 As shown, where D max The maximum dose point is at depth d. max Previously, this was the dose-construction zone.
[0040] At least one guide groove 10 is provided on each of the two outer side walls of the mouthpiece. One end of the guide groove 10 extends to the upper end of the mouthpiece, and the other end of the guide groove 10 extends to the lower end of the mouthpiece. The water bag is provided with a guide block on the side that is used to contact the mouthpiece. The number of guide grooves 10 and guide blocks are the same and their positions correspond one-to-one. The water bag can be inserted from the top of the mouthpiece downwards to the outer periphery of the mouthpiece, and the guide block slides from top to bottom into the guide groove 10. Both the guide groove 10 and the guide block are dovetail-shaped.
[0041] This embodiment, through the above design, can achieve true in vivo dose measurement and quantify the comprehensive errors existing in current dose reconstruction technologies. These errors originate from EPID hardware (non-aqueous equivalent detector), dose algorithms (simplified physical assumptions), processes (EPID relies on manual calibration and judgment), and dynamic changes during radiotherapy (anatomical structure, body position, irradiation parameters), etc. This embodiment can measure the true point dose in the patient's mouth through the built-in TLD. This dose can be verified with multiple calculated doses, and since the TLD is close to the oral mucosa, it can be considered as the actual dose received by the oral mucosa, which can provide a reference for clinical decision-making.
[0042] In this embodiment, for the filling design of the oral impression material on the occlusal part 3, the oral impression material can be alginate or silicone rubber, etc. When alginate is selected, the powder and water are mixed in proportion (the powder-to-water ratio is usually 1:2~3) and quickly stirred until uniform and free of particles; when silicone rubber is selected, it is separated into matrix and catalyst, and mixed in proportion according to the instructions (e.g., 10:1) and stirred evenly.
[0043] During impression taking, an adhesive layer is applied to the concave surface 6 of the occlusal portion 3 to prevent the oral impression material from separating from the occlusal portion 3. The prepared oral impression material is quickly placed into the concave surface 6 of the occlusal portion 3, avoiding air bubbles. The amount of oral impression material should cover the bottom and edges of the concave surface 6 of the occlusal portion 3, with a uniform thickness (approximately 5mm to 8mm). Then, the mouthpiece and tongue depressor 1 in this embodiment are gently placed into the patient's mouth, aligned with the teeth, and pressure is slowly applied to make the oral impression material adhere to the teeth, gums, and surrounding area. For soft tissues (such as the vestibular sulcus), guide the patient to close their mouth to ensure the oral impression material fills all details. Wait for the oral impression material to solidify, keeping the mouthpiece and occlusion stable during solidification to prevent movement. For alginate materials, solidification takes approximately 3-5 minutes (affected by temperature; lower water temperatures result in slower solidification). For silicone rubber materials, solidification time varies from 2 to 10 minutes depending on the type (shorter for rapid types, longer for standard types). Wait for the oral impression material to completely solidify (it should feel elastic and not sticky to the touch). This simple operation ensures individualized fit and occlusal repeatability of the mouthpiece in this embodiment, lowering the barrier to widespread application.
[0044] like Figure 8 As shown, the expected dose before the treatment plan is implemented, whether obtained through calculation or phantom measurement, cannot take into account the impact of patient factors on the dose during treatment; such as Figure 9 As shown, various factors can cause differences between the actual and expected doses during treatment plan execution; such as... Figure 10As shown, the reconstructed dose after treatment plan execution is limited by current technology and influenced by various factors, making it impossible to accurately reproduce the in vivo dose. This embodiment combines a TLD (Total Displacement Diagnostic Device) with a mouthpiece to measure the in vivo dose. In practical applications, the actual in vivo dose of the patient is measured by reading TLD data, validating the results calculated under various interferences, providing a reference for clinical decision-making, and offering a solution for quantifying and reducing the error between treatment plan design and execution. In this embodiment, the addition of the mouthpiece is expected to reduce positioning errors, thereby reducing the difficulty of deformed image registration, thus reducing the mapping error between the sCT generated based on deformed image registration and the planning image, and making the dose calculation and reconstruction results more accurate.
[0045] By filling the water bladder with a substance of fixed electron density, the stability of the sCT process generated using artificial intelligence methods can be verified, thereby verifying the stability of the generated model; filling the water bladder with a contrast agent solution can help improve the accuracy of manual delineation in the images.
[0046] Specific examples have been used to illustrate the principles and implementation methods of this invention. The descriptions of the above embodiments are only for the purpose of helping to understand the method and core ideas of this invention. Furthermore, those skilled in the art will recognize that, based on the ideas of this invention, there will be changes in the specific implementation methods and application scope. Therefore, the content of this specification should not be construed as a limitation of this invention.
Claims
1. A personalized water-filled balloon-dose measurement multimodal oral fixation device for radiotherapy, characterized in that: The device includes a mouthpiece and an expansion element. The mouthpiece is placed inside a patient's mouth, and its bottom surface contacts the back of the patient's tongue. The mouthpiece has a breathing channel that extends through it along its length. One end of the mouthpiece has a biting portion for the patient to bite on, and the biting portion is filled with oral impression material. The expansion element is located on the outer periphery of the mouthpiece and is detachably connected to it. The expansion element conforms to the patient's hard palate. The mouthpiece also has a dose detection element for detecting the radiation dose received by the patient's tongue.
2. The individualized water-filled balloon-dose measurement multimodal oral fixation device for radiotherapy according to claim 1, characterized in that: The mouthpiece includes a tongue depressor and a body element. The body element is integrally formed on the upper surface of the tongue depressor. The lower surface of the tongue depressor is used to contact the back of the patient's tongue. Both sides of the tongue depressor extend beyond the sides of the body element. The dose detection element is mounted on the tongue depressor, avoiding the position of the body element. One end of the body element is flush with the tongue depressor. The other end of the body element is provided with the biting part, which extends beyond the tongue depressor. The breathing channel is opened on the body element.
3. The individualized water-filled balloon-dose measurement multimodal oral fixation device for radiotherapy according to claim 2, characterized in that: The dose detection element can be detachably connected to the tongue depressor, or the dose detection element can be encapsulated within the tongue depressor.
4. The individualized water-filled balloon-dose measurement multimodal oral fixation device for radiotherapy according to claim 2, characterized in that: The tongue depressor is semi-elliptical, with its front end being an arc-shaped surface. The front end of the tongue depressor is used to fit the patient's mandibular alveolar process, while the rear end of the tongue depressor is flat. The rear end of the tongue depressor is used to align with the line connecting the patient's two second molars or the line connecting the patient's two third molars.
5. The individualized water-filled balloon-dose measurement multimodal oral fixation device for radiotherapy according to claim 2, characterized in that: The dose detection element includes multiple thermoluminescent dosimeters, which are evenly arranged on both sides of the main body element.
6. The individualized water-filled balloon-dose measurement multimodal oral fixation device for radiotherapy according to claim 2, characterized in that: The cross-section of the main body element and the cross-section of the breathing channel are both isosceles trapezoids, with the upper base of the isosceles trapezoid close to the patient's hard palate and the lower base of the isosceles trapezoid close to the patient's tongue.
7. The individualized water-filled balloon-dose measurement multimodal oral fixation device for radiotherapy according to claim 1, characterized in that: Both the upper and lower surfaces of the occlusal portion are provided with concave curved surfaces, and the concave curved surfaces are used to fill oral impression material.
8. The individualized water-filled balloon-dose measurement multimodal oral fixation device for radiotherapy according to claim 1, characterized in that: The expansion element is a water bladder with an injection hole. The injection hole is sealed with a heparin cap and used with a disposable syringe. The side of the water bladder that contacts the mouthpiece is made of a rigid material, and the shape of the water bladder on the side that contacts the mouthpiece corresponds to the shape of the mouthpiece. The other side of the water bladder is made of an elastic material and is used to fit the patient's hard palate.
9. The individualized water-filled balloon-dose measurement multimodal oral fixation device for radiotherapy according to claim 8, characterized in that: The water bladder is divided into a full-mouth water bladder or a half-mouth water bladder. The full-mouth water bladder covers the top and sides of the mouthpiece, and the half-mouth water bladder covers one side and part of the top of the mouthpiece. The water bladder is used to fill water or contrast agent aqueous solution.
10. The individualized water-filled balloon-dose measurement multimodal oral fixation device for radiotherapy according to claim 8, characterized in that: The mouthpiece has at least one guide groove on each of its two outer side walls. One end of the guide groove extends to the upper end of the mouthpiece, and the other end extends to the lower end of the mouthpiece. The water bladder has a guide block on the side that contacts the mouthpiece. The number of guide grooves and guide blocks are the same and their positions correspond one-to-one. The water bladder can be inserted from above the mouthpiece downwards to the outer periphery of the mouthpiece, and the guide block slides from top to bottom into the guide groove. Both the guide groove and the guide block are dovetail-shaped.