Automatic administration anesthesia patch

Abstract

The invention belongs to the technical field of local anesthesia, and particularly relates to an automatic drug delivery anesthesia patch which comprises a paper tearing layer, a pasting layer, an injection layer and a drug storage layer which are attached in sequence, and the injection layer comprises an injection bin, a microneedle and a driving mechanism; the medicine storage layer comprises a medicine storage bin and an anesthetic conveying mechanism, and the pasting layer, the injection bin and the medicine storage bin are sequentially attached to one another; anesthetic is stored in the medicine storage bin; the number of the microneedles is multiple, and the multiple microneedles are movably installed in the injection bin. The driving mechanism is mounted in the injection bin; the medicine storage bin is communicated with the injection bin through the anesthetic conveying mechanism; and the microneedle is provided with an injection channel communicated with the injection bin. The anesthesia patch can carry more anesthetic drugs, better anesthesia is achieved, the anesthesia time is longer, additional pressure does not need to be applied in the injection acupuncture process, the injection acupuncture process is rapid, process stabbing pain can be effectively reduced, and painless anesthesia is better achieved.

Description

Technical Field

[0001] This invention belongs to the field of local anesthesia technology, specifically relating to an automated drug delivery anesthesia patch. Background Technology

[0002] Currently, the main methods of local anesthesia include traditional injection, infiltration anesthesia, and topical anesthesia. Traditional injection can cause unbearable pain and discomfort for patients, leading to poor patient compliance. Infiltration anesthesia has a lower drug transdermal penetration rate than traditional injection, and its anesthetic effect lasts longer, while still requiring a syringe and causing pain. Topical anesthesia is a type of painless anesthesia, which involves applying anesthetic to the affected area, allowing the anesthetic components to penetrate the tissue through the epidermis to achieve an anesthetic effect. However, it has drawbacks such as slow onset and less than ideal anesthetic effect.

[0003] To address the aforementioned technical problems, various microneedle patches have been developed, including a microneedle patch for local anesthesia disclosed in patent number CN202021375350.3, a broad-spectrum antibacterial polyionic liquid microneedle patch and method for local anesthesia disclosed in CN202211591338.X, a method for preparing a microneedle patch for rapid local anesthesia disclosed in CN202211091797.1, and a microneedle patch and method for preparing a microneedle patch suitable for local anesthesia disclosed in CN202011038493.X. Microneedle patches are transdermal drug delivery systems that have been widely studied in recent years. They consist of a series of microneedles whose tips can penetrate the stratum corneum of the skin, opening micron-level channels in the skin to deliver anesthetic drugs to the subcutaneous layer, thereby allowing the anesthetic drugs to participate in blood circulation. Compared to facial anesthesia, microneedle patches can greatly improve the transdermal drug delivery efficiency. At the same time, the micron-level needle tips do not touch pain nerves after penetrating the subcutaneous layer. Therefore, microneedle patches are widely used in painless treatment. This invention draws on the principle of microneedle patches to design a novel automatic drug delivery anesthesia patch. This anesthesia patch can carry more anesthetic drugs, achieving better anesthesia and longer anesthesia time. Moreover, no additional pressure is required during the injection and acupuncture process, which is rapid and can effectively reduce the pain during the process, thus achieving better painless anesthesia. Furthermore, the release rate of anesthetic drugs can be adjusted, and it can be connected to an external IV drip to achieve long-term drug delivery, adapting to the needs of different anesthesia scenarios. Summary of the Invention

[0004] This invention draws on the principle of microneedle patches to design a novel automatic drug delivery anesthesia patch. This anesthesia patch can carry more anesthetic drugs, achieving better anesthesia and longer anesthesia time. Moreover, no additional pressure is required during the injection and acupuncture process, which is rapid and can effectively reduce the pain during the process, thus achieving better painless anesthesia. Furthermore, the release rate of anesthetic drugs can be adjusted, and it can be connected to an external IV drip to achieve long-term drug delivery, adapting to the needs of different anesthesia scenarios.

[0005] The specific technical solution adopted in this invention is as follows:

[0006] An automated drug delivery anesthetic patch includes a paper-peeling layer, an adhesive layer, an injection layer, and a drug storage layer sequentially bonded together. The injection layer includes an injection chamber, microneedles, and a driving mechanism. The drug storage layer includes a drug storage chamber and an anesthetic drug delivery mechanism. The adhesive layer, injection chamber, and drug storage chamber are sequentially bonded together. The drug storage chamber stores anesthetic drugs. A plurality of microneedles are movably installed within the injection chamber. The adhesive layer has a plurality of microholes, the same number as the number of microneedles and positioned opposite each other. The driving mechanism is installed within the injection chamber and drives the microneedles to move toward and out of the microholes. The drug storage chamber is connected to the injection chamber via the anesthetic drug delivery mechanism to deliver the anesthetic drugs from the storage chamber to the injection chamber. Each microneedle has an injection channel communicating with the injection chamber, and the injection channel passes through the microneedle.

[0007] Furthermore, the anesthetic drug delivery mechanism includes a delivery pipe and a valve. The drug storage chamber is made of an elastic material. The anesthetic drug fills the drug storage chamber and supports it, creating pressure inside the drug storage chamber. The drug storage chamber is connected to the injection chamber through the delivery pipe, and the valve is located on the delivery pipe.

[0008] Furthermore, the medicine storage compartment is provided with several reinforcing ribs connecting the upper and lower inner sides of the medicine storage compartment.

[0009] Furthermore, the injection chamber is divided into a gas storage chamber and a drug storage chamber. The driving mechanism includes a diaphragm, a movable baffle, and a gas generating component located in the gas storage chamber. The drug storage chamber is connected to the drug storage chamber via the anesthetic drug delivery mechanism. A plurality of microneedles are located in the drug storage chamber. Located in the drug storage chamber, a plurality of injection holes, the same number as the microneedles and positioned opposite each other, are provided below the injection chamber. A plurality of through holes, the same number as the microneedles and positioned opposite each other, are provided above the injection chamber. The through holes connect the gas storage chamber and the drug storage chamber, and each through hole is sealed by the diaphragm. Corresponding to each through hole, a sealing sleeve is provided on the inner side of the drug storage chamber.

[0010] For each microneedle: the upper part of the microneedle is movably and sealed to the sealing sleeve, the lower part of the microneedle is movably and sealed to the injection hole, and the inlet of the injection channel is located above the microneedle; the movable baffle is located between the injection chamber and the adhesive layer, and the movable baffle has a plurality of transition holes, the same number as the microneedles and opposite in position, and the end of the movable baffle extends into the gas storage chamber; in the initial state, the transition holes are offset from the injection hole and the microhole, so that the injection hole and the microhole are not connected, and the sealing sleeve covers the inlet of the injection channel;

[0011] When the paper-peeling layer is peeled off and the adhesive layer is applied to the skin, the gas generating component generates gas. The generated gas pushes several of the diaphragms to bulge towards the microneedles and pushes the microneedles towards the micropores. At the same time, the generated gas pushes the moving baffle to move, so that the transition hole is aligned with the injection hole and the micropore, and the injection hole and the micropore are connected. The microneedles move sequentially through the transition hole and the micropore and are inserted into the skin. When the microneedles move towards the micropores, the inlet of the injection channel is exposed from inside the sealing sleeve, so that the inlet of the injection channel is connected to the drug storage chamber. The anesthetic drug in the drug storage chamber is injected into the skin through the injection channel.

[0012] Furthermore, the gas generating assembly includes an explosion chamber, a resistance wire, a battery, a housing, an insulating sheet, and gunpowder. The resistance wire, battery, housing, and gunpowder are located inside the explosion chamber, and the battery is installed inside the housing. One end of the insulating sheet is located outside the injection chamber and connected to the tear-off paper layer, while the other end extends into the explosion chamber.

[0013] The middle of the resistance wire is located inside the gunpowder, and both ends of the resistance wire extend out of the gunpowder. One end of the resistance wire is in contact with the electrode at one end of the battery, and the other end of the resistance wire is in contact with the electrode at the other end of the electrode via the other end of the insulating sheet. The explosion chamber is provided with an exhaust port that connects the gas storage chamber and the explosion chamber.

[0014] When the paper layer is torn off and the insulating sheet is pulled out of the explosion chamber, the other end of the resistance wire comes into contact with the electrode at the other end of the electrode. The resistance wire is connected to the battery, and the gunpowder is ignited to generate gas. The gas is discharged into the gas storage chamber through the exhaust port.

[0015] Furthermore, the upper part of the microneedle is movably and sealed to the sealing sleeve via an upper sealing ring, and the lower part of the microneedle is movably and sealed to the injection hole via a lower sealing ring.

[0016] Furthermore, the injection chamber is equipped with a partition, which divides the injection chamber into a gas storage chamber and a drug storage chamber; the gas storage chamber is equipped with several internal reinforcing ribs; and there are multiple exhaust ports.

[0017] Furthermore, several of the microneedles are arranged in a matrix-distributed manner.

[0018] Furthermore, one end of the tear-off paper layer extends toward the injection chamber and is disposed in conjunction with the side of the adhesive layer and the injection chamber, and one end of the tear-off paper layer is connected to the insulating sheet.

[0019] Furthermore, the number of gas generating components is multiple.

[0020] The beneficial effects of this invention are as follows: In use, the paper-tearable layer is peeled off from the adhesive layer and then adhered to the skin requiring local anesthesia via the adhesive layer. After adhesion, a driving mechanism drives several microneedles to move towards and through several micropores. Simultaneously, an anesthetic drug delivery mechanism delivers anesthetic drugs from the storage chamber to the injection chamber. As the microneedles move, the anesthetic drugs in the injection chamber enter the injection channels of the microneedles. When the microneedles penetrate the skin through the micropores, the anesthetic drugs are injected into the skin through the injection channels, achieving automatic drug delivery. Under the action of the driving mechanism, the injection acupuncture process does not require additional pressure or pressing to insert the microneedles into the skin. The injection acupuncture process is rapid, effectively reducing pain and achieving painless anesthesia. Furthermore, the release rate of the anesthetic drugs is adjustable, and an external IV drip can be connected for long-term drug delivery, adapting to different anesthesia scenarios and offering greater flexibility and convenience. Attached Figure Description

[0021] To more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0022] Figure 1 This is a perspective view of the present invention;

[0023] Figure 2 for Figure 1 A 3D image after removing the paper layer;

[0024] Figure 3 for Figure 1 A cross-sectional diagram;

[0025] Figure 4 for Figure 3 A magnified view on the left;

[0026] Figure 5 for Figure 3 A magnified view on the right;

[0027] Figure 6 To be Figure 1 A 3D view of the top of the medicine storage compartment after sectional cutting;

[0028] Figure 7 To be Figure 1 A 3D view of the top of the injection chamber after sectional cutting;

[0029] Figure 8 for Figure 1 A partial cross-sectional view of the corresponding gas generating component;

[0030] Figure 9 This is a perspective view of the gas generating component of the present invention;

[0031] Figure 10 for Figure 9 A cross-sectional diagram;

[0032] Figure 11 This is a three-dimensional view of the microneedle of the present invention.

[0033] The above figure labels:

[0034] 1. Paper-peeling layer; 2. Adhesive layer; 201. Micropores; 20. Fixing plate; 21. Backing adhesive; 3. Injection layer; 30. Injection chamber; 301. Gas storage chamber; 302. Drug storage chamber; 303. Partition; 31. Microneedle; 32. Moving baffle; 33. Diaphragm; 34. Sealing sleeve; 35. Upper sealing ring; 36. Lower sealing ring; 37. Gas generating assembly; 38. Inner reinforcing rib; 320. Transition hole; 310. Injection channel; 3100. Inlet; 370. Explosion chamber; 371. Gunpowder; 372. Battery; 373. Resistance wire; 374. Insulating sheet; 3701. Exhaust port; 4. Drug storage layer; 40. Drug storage chamber; 41. Anesthetic drug delivery mechanism; 410. Delivery pipeline; 411. Valve; 42. Reinforcing rib. Detailed Implementation

[0035] To facilitate understanding of the present invention, a more complete description will be given below with reference to the accompanying drawings. Preferred embodiments of the invention are shown in the drawings. However, the invention can be implemented in many different forms and is not limited to the embodiments described herein. Rather, these embodiments are provided to provide a thorough and complete understanding of the disclosure of the invention.

[0036] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention pertains. The terminology used herein in the description of the invention is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. The term "and / or" as used herein includes any and all combinations of one or more of the associated listed items.

[0037] When describing positional relationships, unless otherwise specified, when an element is referred to as being "on" another element, it may be directly on the other element or there may be intermediate elements. It is also understood that when an element is referred to as being "between" two elements, it may be the only one between the two elements, or there may be one or more intermediate elements.

[0038] When using the terms “including,” “having,” and “comprising” as described herein, another component may be added unless explicitly qualifying terms such as “only,” “consisting of,” etc. are used. Unless otherwise stated, singular terms may include plural forms and should not be construed as having a quantity of one.

[0039] It should also be understood that, in interpreting an element, although not explicitly described, the element is interpreted as including a range of error, which should be within the acceptable deviation range of a particular value as determined by a person skilled in the art. For example, "approximately," "about," or "substantially" can mean within one or more standard deviations, without limitation herein.

[0040] like Figure 1-11 As shown, this embodiment provides an automatic drug delivery anesthetic patch, comprising a paper-peeling layer 1, an adhesive layer 2, an injection layer 3, and a drug storage layer 4 sequentially bonded together. The injection layer 3 includes an injection chamber 30, microneedles 31, and a driving mechanism; the drug storage layer 4 includes a drug storage chamber 40 and an anesthetic drug delivery mechanism 41. The adhesive layer 2, injection chamber 30, and drug storage chamber 40 are sequentially bonded together; the drug storage chamber 40 stores anesthetic drugs; the number of microneedles 31 is plurality of, and the plurality of microneedles 31 are movably installed within the injection chamber 30. The adhesive layer 2 is provided with... A plurality of micro-holes 201, the same number as the microneedles 31 and positioned opposite each other; the driving mechanism is installed inside the injection chamber 30 and is used to drive the microneedles 31 to move toward and out of the micro-holes 201; the drug storage chamber 40 is connected to the injection chamber 30 through the anesthetic drug delivery mechanism 41 to deliver the anesthetic drug in the drug storage chamber 40 to the injection chamber 30; the microneedles 31 are provided with injection channels 310 communicating with the injection chamber 30, and the injection channels 310 penetrate the microneedles 31. Preferably, as follows: Figure 2 As shown, several of the microneedles 31 are arranged in a matrix to improve the anesthetic effect.

[0041] The anesthetic patch in this embodiment is made of a flexible material that can be bent at a certain angle to conform to the skin. In use, the paper-tearable layer 1 is peeled off from the adhesive layer 2 and then adhered to the skin requiring local anesthesia via the adhesive layer 2. After adhesion, the driving mechanism drives several microneedles 31 to move towards and through several micro-holes 201. Simultaneously, the anesthetic drug delivery mechanism 41 delivers the anesthetic drug from the storage tank 40 to the injection tank 30. Thus, as the microneedles 31 move, the anesthetic drug in the injection tank 30 enters the injection channel 310 of the microneedles 31. When the microneedles 31 penetrate the skin through the micro-holes 201, the anesthetic drug is injected into the skin through the injection channel 310, achieving automatic drug delivery. In this embodiment, under the action of the driving mechanism, no additional pressure is required during the injection acupuncture process; there is no need to press to insert the microneedles 31 into the skin. The injection acupuncture process is rapid, effectively reducing pain and achieving painless anesthesia.

[0042] This embodiment stores anesthetic drugs in the drug storage compartment 40. Compared to pre-storing the anesthetic drugs in the microneedles 31, it can carry more anesthetic drugs, achieving better anesthesia and a longer duration of anesthesia. Furthermore, an IV drip needle can be inserted into the drug storage compartment 40 to connect to an external IV drip, enabling long-term drug delivery. This adapts to different anesthesia scenarios and is more flexible and convenient to use. Additionally, the anesthetic patch in this embodiment can be individually packaged for easy carrying and flexible use.

[0043] In this preferred embodiment, the adhesive layer 2 consists of a fixing plate 20 and an adhesive backing 21 bonded to the fixing plate 20. The adhesive backing 21 adheres to the tear-off paper layer 1. When the tear-off paper layer 1 is peeled off, it adheres to the skin through the adhesive backing 21. Correspondingly, micropores 201 are provided on the fixing plate 20 and the adhesive backing 21. In this embodiment, the fixing plate 20, the injection chamber 30, and the drug storage chamber 40 can be bonded together using adhesive or other bonding methods. Of course, other existing fixing methods can also be used to form a single unit. This is conventional technology and not the focus of this embodiment, so it will not be described in detail.

[0044] In a further preferred embodiment, the anesthetic drug delivery mechanism 41 includes a delivery pipe 410 and a valve 411. The drug storage chamber 40 is made of an elastic material. The anesthetic drug fills the drug storage chamber 40 and supports the drug storage chamber 40, so that there is pressure inside the drug storage chamber 40. The drug storage chamber 40 is connected to the injection chamber 30 through the delivery pipe 410. The valve 411 is provided on the delivery pipe 410.

[0045] In this embodiment, the drug storage chamber 40 is made of an elastic material, which can be any existing plastic, etc., and is not specifically limited thereto. Because the anesthetic drug supports the storage chamber 40, pressure is created inside the storage chamber 40 due to the elasticity. Therefore, when the valve 411 is opened, the anesthetic drug in the storage chamber 40 automatically flows into the injection chamber 30 under pressure, achieving automatic delivery of the anesthetic drug. Simultaneously, by adjusting the opening of the valve 411, the outflow rate of the anesthetic drug is adjusted, thereby regulating the injection rate and achieving a sustained-release effect, resulting in a better anesthetic effect.

[0046] In a further preferred embodiment, the drug storage chamber 40 is provided with a plurality of reinforcing ribs 42 connecting the upper and lower inner sides of the drug storage chamber 40. These reinforcing ribs 42 ensure that the drug storage chamber 40 remains flat, preventing it from bulging when the anesthetic drug is injected and the chamber is stretched. The reinforcing ribs 42 hold the drug storage chamber 40 in place, thus preventing it from bulging and ensuring the anesthetic patch remains flat, resulting in better appearance and usability. Figure 6 As shown, among the various reinforcing ribs 42, some reinforcing ribs 42 are arranged horizontally, some are arranged vertically, and of course, other structural forms can also be adopted.

[0047] In a further preferred embodiment, the injection chamber 30 is divided into a gas storage chamber 301 and a drug storage chamber 302. The driving mechanism includes a diaphragm 33, a movable baffle 32, and a gas generating assembly 37 located in the gas storage chamber 301. The drug storage chamber 302 is connected to the drug storage chamber 40 via the anesthetic drug delivery mechanism 41. A plurality of microneedles 31 are located in the drug storage chamber 302. Figure 3 and 4 As shown, preferably, the injection chamber 30 is provided with a partition 303, which divides the injection chamber 30 into the gas storage chamber 301 and the drug storage chamber 302.

[0048] Located within the drug storage chamber 302, below the injection chamber 30, there are several injection holes of the same number and opposite positions as the microneedles 31. Above the injection chamber 30, there are several through holes of the same number and opposite positions as the microneedles 31. The through holes connect the gas storage chamber 301 and the drug storage chamber 302, and each through hole is sealed by the diaphragm 33. Corresponding to each through hole, a sealing sleeve 34 is provided on the inner side of the drug storage chamber 302.

[0049] For each microneedle 31: the upper part of the microneedle 31 is movably and sealed to the sealing sleeve 34, the lower part of the microneedle 31 is movably and sealed to the injection hole, and the inlet 3100 of the injection channel 310 is located above the microneedle 31; the movable baffle 32 is located between the injection chamber 30 and the adhesive layer 2, and the movable baffle 32 is provided with a plurality of transition holes 320, which are the same number as the microneedles 31 and are opposite in position, and the end of the movable baffle 32 extends into the gas storage chamber 301; in the initial state, the transition holes 320 are offset from the injection hole and the microhole 201, so that the injection hole and the microhole 201 are not connected, and the sealing sleeve 34 covers the inlet 3100 of the injection channel 310.

[0050] like Figure 4 and 5 As shown, in this preferred embodiment, the upper part of the microneedle 31 is movably sealed to the sealing sleeve 34 via an upper sealing ring 35, and the lower part of the microneedle 31 is movably sealed to the injection hole via a lower sealing ring 36. The upper sealing ring 35 and the lower sealing ring 36 achieve the sealing of the injection chamber 30, ensuring that the anesthetic drug is effectively stored in the injection chamber 30 and will not leak out.

[0051] In this embodiment, when the driving mechanism is used, the paper-peeling layer 1 is peeled off, and the adhesive layer 2 is applied to the skin. The gas generating component 37 generates gas, which is then stored in the gas storage chamber 301. The gas pushes several of the diaphragms 33 to bulge towards the microneedles 31, thereby pushing the microneedles 31 towards the micropores 201. Simultaneously, the gas pushes the moving baffle 32 to move, aligning the transition hole 320 with the injection hole and the micropore 201. The microneedle 31 is connected to the micropore 201. It moves through the transition hole 320 and the micropore 201 in sequence and is inserted into the skin. When the microneedle 31 moves toward the micropore 201, the inlet 3100 of the injection channel 310 is exposed from the sealing sleeve 34, so that the inlet 3100 of the injection channel 310 is connected to the drug storage cavity 302. The anesthetic drug in the drug storage cavity 302 is injected into the skin through the injection channel 310, completing the injection acupuncture process.

[0052] Preferably, in this embodiment, the number of gas generating components 37 is multiple. For example... Figure 7 As shown, the number of gas generating components 37 is two, but it can also be three, etc., which is not limited to increase the amount of gas generated by the gas generating components 37, increase the driving power of the driving mechanism, and increase the speed of injection needle puncture.

[0053] In this preferred embodiment, Figure 4 and 5As shown, the wall of the injection chamber 30 below is thicker than other parts, which increases the mating length between the microneedle 31 and the injection hole, ensuring that the microneedle 31 and the injection chamber 30 are effectively and stably installed, and that the microneedle 31 can move effectively and stably.

[0054] This embodiment is further preferably preferred, such as Figure 8-10 As shown, the gas generating assembly 37 includes an explosion chamber 370, a resistance wire 373, a battery 372, a housing, an insulating sheet 374, and gunpowder 371. The resistance wire 373, battery 372, housing, and gunpowder 371 are located within the explosion chamber 370, and the battery 372 is installed within the housing. One end of the insulating sheet 374 is located outside the injection chamber 30 and connected to the tear-off paper layer 1, while the other end extends into the explosion chamber 370. The middle of the resistance wire 373 is located within the gunpowder 371, and both ends of the resistance wire 373 extend beyond the gunpowder 371. One end of the resistance wire 373 is in contact with an electrode at one end of the battery 372, and the other end of the resistance wire 373, via the other end of the insulating sheet 374, is in contact with an electrode at the other end of the battery. The explosion chamber 370 is provided with an exhaust port 3701 connecting the gas storage chamber 301 and the explosion chamber 370. The housing is used to protect the battery 372.

[0055] In this embodiment, when using the gas generating component 37, the paper-peeling layer 1 below the adhesive layer 2 is first peeled off. After the adhesive layer 2 is applied to the skin, the paper-peeling layer 1 is then peeled off relative to the adhesive layer 2, simultaneously pulling the insulating sheet 374 out of the explosion chamber 370. The other end of the resistance wire 373 contacts the electrode at the other end of the electrode. The resistance wire 373 is connected to the battery 372. The gunpowder 371 is ignited to generate gas, which is then discharged into the gas storage chamber 301 through the exhaust port 3701. The principle of the gas generating component 37 in this embodiment is the same as that of existing automotive airbags, ensuring safety and reliability. Preferably, in this embodiment... Figure 9 As shown, there are multiple exhaust ports 3701. The other end of the resistance wire 373 has a spring force that moves towards the electrode at the other end of the battery 372. Therefore, when the insulating sheet 374 is pulled out, the other end of the resistance wire 373 is attached to the electrode at the other end of the electrode.

[0056] In this preferred embodiment, Figure 4 As shown, one end of the tear-off layer 1 extends toward the injection chamber 30 and is disposed in conjunction with the adhesive layer 2 and the side of the injection chamber 30. One end of the tear-off layer 1 is connected to the insulating sheet 374.

[0057] In a further preferred embodiment, the gas storage cavity 301 is provided with several inner reinforcing ribs 38. Since the anesthesia patch in this embodiment is made of a flexible material, when the gas generating component 37 generates gas, the gas storage cavity 301 stores gas and is pressurized. To ensure that the gas storage cavity 301 does not bulge, the several inner reinforcing ribs 38 hold the gas storage cavity 301 in place, ensuring that the gas storage cavity 301 remains flat. Figure 7 As shown, the inner reinforcing rib 38 has a cross-shaped structure, but other structural forms can also be used.

[0058] The foregoing has shown and described the basic principles, main features, and advantages of the present invention. Those skilled in the art should understand that the present invention is not limited to the above embodiments. The embodiments and descriptions in the specification are merely illustrative of the principles of the invention. Various changes and modifications can be made to the invention without departing from its spirit and scope, and all such changes and modifications fall within the scope of the present invention as claimed. The scope of protection of this invention is defined by the appended claims and their equivalents.

Claims

1. An automatic drug delivery patch, characterized in that, The device comprises a paper-peeling layer (1), an adhesive layer (2), an injection layer (3), and a drug storage layer (4) that are sequentially bonded together. The injection layer (3) includes an injection chamber (30), a microneedle (31), and a drive mechanism. The drug storage layer (4) includes a drug storage chamber (40) and an anesthetic drug delivery mechanism (41). The adhesive layer (2), the injection chamber (30), and the drug storage chamber (40) are sequentially bonded together. The drug storage chamber (40) contains anesthetic drugs. The number of microneedles (31) is several, and several microneedles (31) are movably installed in the injection chamber (30). The adhesive layer (2) is provided with several microholes (201) that are the same number as the number of microneedles (31) and are positioned opposite each other. The driving mechanism is installed in the injection chamber (30) and is used to drive the microneedles (31) to move toward the microholes (201) and pass through the microholes (201). The drug storage chamber (40) is connected to the injection chamber (30) through the anesthetic drug delivery mechanism (41) to deliver the anesthetic drug in the drug storage chamber (40) to the injection chamber (30). The microneedles (31) are provided with injection channels (310) that communicate with the injection chamber (30) and the injection channels (310) penetrate the microneedles (31).

2. The self-administered anesthetic patch of claim 1, wherein, The anesthetic drug delivery mechanism (41) includes a delivery pipe (410) and a valve (411). The drug storage chamber (40) is made of elastic material. The anesthetic drug fills the drug storage chamber (40) and supports the drug storage chamber (40), so that there is pressure inside the drug storage chamber (40). The drug storage chamber (40) is connected to the injection chamber (30) through the delivery pipe (410). The valve (411) is located on the delivery pipe (410).

3. The self-administered anesthetic patch of claim 2, wherein, The medicine storage compartment (40) is provided with a number of reinforcing ribs (42) connecting the upper and lower inner sides of the medicine storage compartment (40).

4. The self-administered anesthetic patch of claim 1, wherein, The injection chamber (30) is divided into a gas storage chamber (301) and a drug storage chamber (311). The driving mechanism includes a diaphragm (33), a movable baffle (32), and a gas generating assembly (37) located in the gas storage chamber (301). The drug storage chamber (311) is connected to the drug storage chamber (40) through the anesthetic drug delivery mechanism (41). A plurality of microneedles (31) are located in the drug storage chamber (311). The injection chamber (30) has a plurality of injection holes at its lower part, which are the same number as the microneedles (31) and are positioned opposite each other. The injection chamber (30) has a plurality of through holes at its upper part, which are the same number as the microneedles (31) and are positioned opposite each other. The through holes connect the gas storage chamber (301) and the drug storage chamber (311), and each through hole is sealed by the diaphragm (33). For each through hole, a sealing sleeve (34) is provided on the inner side of the drug storage chamber (311). For each microneedle (31): the upper part of the microneedle (31) is movably sealed to the sealing sleeve (34), the lower part of the microneedle (31) is movably sealed to the injection hole, and the inlet of the injection channel (310) is located above the microneedle (31); the movable baffle (32) is located between the injection chamber (30) and the adhesive layer (2), and the movable baffle (32) is provided with a plurality of transition holes (320) that are the same number as the microneedles (31) and opposite in position, and the end of the movable baffle (32) extends into the gas storage chamber (301); in the initial state, the transition holes (320) are offset from the injection hole and the microhole (201) so that the injection hole and the microhole (201) are not connected, and the sealing sleeve (34) covers the inlet of the injection channel (310); When the paper-peeling layer (1) is peeled off and the adhesive layer (2) is applied to the skin, the gas generating component (37) generates gas. The generated gas pushes several of the diaphragms (33) to bulge towards the microneedles (31) and pushes the microneedles (31) to move towards the micropores (201). At the same time, the generated gas pushes the moving baffle (32) to move, so that the transition hole (320) is aligned with the injection hole and the micropore (201). 01) When connected, the microneedle (31) moves through the transition hole (320) and the microhole (201) in sequence and is inserted into the skin. When the microneedle (31) moves toward the microhole (201), the inlet of the injection channel (310) is exposed from the sealing sleeve (34), so that the inlet of the injection channel (310) is connected to the drug storage cavity (311). The anesthetic drug in the drug storage cavity (311) is injected into the skin through the injection channel (310).

5. The self-administered anesthetic patch of claim 4, wherein, The gas generating assembly (37) includes an explosion chamber (370), a resistance wire (373), a battery (372), a housing, an insulating sheet (374), and gunpowder (371). The resistance wire (373), battery (372), housing, and gunpowder (371) are located inside the explosion chamber (370), and the battery (372) is installed inside the housing. One end of the insulating sheet (374) is located outside the injection chamber (30) and connected to the tear-off paper layer (1), and the other end extends into the explosion chamber (370). The middle of the resistance wire (373) is located inside the gunpowder (371), and both ends of the resistance wire (373) extend out of the gunpowder (371). One end of the resistance wire (373) is in contact with the electrode at one end of the battery (372), and the other end of the resistance wire (373) is in contact with the electrode at the other end of the electrode via the other end of the insulating sheet (374). The explosion chamber (370) is provided with an exhaust port (3701) that connects the gas storage chamber (301) and the explosion chamber (370). When the paper layer (1) is torn off and the insulating sheet (374) is pulled out from the explosion chamber (370), the other end of the resistance wire (373) comes into contact with the electrode at the other end of the electrode. The resistance wire (373) is connected to the battery (372). The gunpowder (371) is ignited to generate gas, and the gas is discharged into the gas storage chamber (301) through the exhaust port (3701).

6. The self-administered anesthetic patch of claim 4, wherein, The microneedle (31) is movably and sealed to the sealing sleeve (34) above by an upper sealing ring (35), and the microneedle (31) is movably and sealed to the injection hole below by a lower sealing ring (36).

7. The self-administered anesthetic patch of claim 4, wherein, The injection chamber (30) is provided with a partition (303), which divides the injection chamber (30) into a gas storage chamber (301) and a drug storage chamber (311); the gas storage chamber (301) is provided with a number of internal reinforcing ribs (38).

8. The self-administered anesthetic patch of claim 1, wherein, Several of the microneedles (31) are arranged in a matrix distribution.

9. The self-administered anesthetic patch of claim 5, wherein, One end of the tear-off layer (1) extends toward the injection chamber (30) and is attached to the side of the adhesive layer (2) and the injection chamber (30). One end of the tear-off layer (1) is connected to the insulating sheet (374). There are multiple exhaust ports (3701).

10. The self-administered anesthetic patch of claim 4, wherein, The number of gas generating components (37) is multiple.

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