Control method of artificial stomach

Abstract

The invention discloses a control method of an artificial stomach, and belongs to the technical field of bionic medical instruments. Under the state that the starting signal is monitored, all the driving pieces are controlled to drive the diastole assembly according to a preset time sequence, so that the corresponding part of the artificial stomach is subjected to contraction or diastole movement, and the content in the artificial stomach is subjected to regular movement from the inlet direction of the artificial stomach to the outlet direction of the artificial stomach. By changing the time point and interval of successive movement of the whole stomach diastole assembly, the pathological characteristics of peristaltic wave conduction delay and starting time sequence disorder are simulated, and then by adjusting the interval between the contraction stop time point and the expansion starting time point, the expression of abnormal extension of the diastole and contraction switching interval or interruption of the peristaltic wave in the pathological state is re-engraved.

Description

TECHNICAL FIELD

[0001] The present application belongs to the technical field of bionic medical devices, and particularly relates to a control method of an artificial stomach. BACKGROUND

[0002] The existing control method of an artificial stomach usually adjusts parameters such as compression amplitude and extrusion pressure to simulate the state of insufficient gastric motility, and the fidelity of the restoration of the gastric peristalsis state in the pathological environment is poor. SUMMARY

[0003] In view of the technical problems in the background art, the present application provides a control method of an artificial stomach, the artificial stomach comprising a plurality of dilation assemblies and a plurality of driving members, each of the driving members being used to drive the dilation assembly to move, and the control method comprising: monitoring a start signal; under the condition that the start signal is monitored, controlling each of the driving members to drive the dilation assembly according to a preset time sequence to make the corresponding part of the artificial stomach contract or dilate, so that the content in the artificial stomach moves regularly from the inlet direction of the artificial stomach to the outlet direction of the artificial stomach.

[0004] In some embodiments, the artificial stomach comprises a fundus part, a body part and an antrum part; The dilation assembly is provided with at least three, and at least one of the dilation assemblies is provided in the fundus part, the body part and the antrum part; The control of each of the driving members to contract or dilate according to the preset time sequence comprises: driving the dilation assembly of the fundus part to contract at a first time point of the fundus part; driving the dilation assembly of the body part to contract at a first time point of the body part; driving the dilation assembly of the antrum part to contract at a first time point of the antrum part; driving the dilation assemblies of the fundus part, the body part and the antrum part to reset the artificial stomach before a reset time point; The first time point of the fundus part is prior to the first time point of the body part, the first time point of the body part is prior to the first time point of the antrum part, and the first time point of the antrum part is prior to the reset time point.

[0005] In some embodiments, after the driving of the dilation assembly of the fundus part to contract at the first time point of the fundus part, the control of each of the driving members to contract or dilate according to the preset time sequence further comprises: stopping the driving of the dilation assembly of the fundus part at a second time point of the fundus part; driving the dilation assembly of the fundus part to expand at a third time point of the fundus part, and stopping the driving of the dilation assembly by the driving member at a fourth time point of the fundus part; The first time point of the gastric fundus precedes the second time point of the gastric fundus, the second time point of the gastric fundus precedes the third time point of the gastric fundus, the third time point of the gastric fundus precedes the fourth time point of the gastric fundus, and the fourth time point of the gastric fundus precedes the repositioning time point; The second time point at the gastric fundus and the first time point at the gastric body are the same time.

[0006] In some embodiments, after the relaxation component of the gastric body is driven to contract at a first time point, controlling each of the driving components to contract or relax according to a preset timing sequence further includes: At the second time point in the gastric body, the contraction of the diastolic assembly of the gastric body is stopped; At a third time point in the stomach body, the dilation component of the stomach body is driven to expand, and at a fourth time point in the stomach body, the driving force on the dilation component is stopped. The first time point of the stomach body precedes the second time point of the stomach body, the second time point of the stomach body precedes the third time point of the stomach body, the third time point of the stomach body precedes the fourth time point of the stomach body, and the fourth time point of the stomach body precedes the repositioning time point; The second time point of the gastric body and the first time point of the gastric antrum are the same time point.

[0007] In some embodiments, after the diastolic component of the gastric antrum is driven to contract at a first time point, the control of each of the driving components to contract or relax according to a preset timing sequence further includes: The contraction of the diastolic component in the antrum is stopped at the second time point in the gastric antrum; At the third time point in the antrum, the dilation component of the gastric body is driven to expand, and at the fourth time point in the antrum, the driving force on the dilation component is stopped. The first time point of the gastric antrum precedes the second time point of the gastric antrum, the second time point of the gastric antrum precedes the third time point of the gastric antrum, the third time point of the gastric antrum precedes the fourth time point of the gastric antrum, and the fourth time point of the gastric antrum precedes the repositioning time point.

[0008] In some embodiments, controlling each of the driving components to contract or relax according to a preset timing sequence includes: At a first point in time, the diastolic components of the gastric fundus are driven to contract; The actuation of the dilatation component at the gastric fundus is stopped at a second time point; At a first point in time, the diastolic component of the gastric body is driven to contract. At the second time point in the gastric body, the driving of the gastric body's dilation component is stopped; At a first point in time, the diastolic component of the gastric antrum is driven to contract. At a third time point, the dilatational component of the gastric fundus is driven to expand; The contraction of the diastolic component in the antrum is stopped at the second time point in the gastric antrum; At a third time point in the gastric body, the diastolic component of the gastric body is driven to expand. At the third time point in the antrum, the dilator of the gastric body is driven to expand; At the fourth time point at the gastric fundus, the actuation of the actuation component for the gastric fundus relaxation assembly is stopped; At the fourth time point in the gastric body, the driving force for the gastric body relaxation assembly is stopped; At the fourth time point in the antrum, the drive of the actuator on the antrum dilator assembly is stopped; The first time point of the gastric fundus precedes the second time point of the gastric fundus, the second time point of the gastric fundus precedes the third time point of the gastric fundus, the third time point of the gastric fundus precedes the fourth time point of the gastric fundus, and the fourth time point of the gastric fundus precedes the repositioning time point; The first time point of the stomach body precedes the second time point of the stomach body, the second time point of the stomach body precedes the third time point of the stomach body, the third time point of the stomach body precedes the fourth time point of the stomach body, and the fourth time point of the stomach body precedes the repositioning time point; The first time point of the gastric antrum precedes the second time point of the gastric antrum, the second time point of the gastric antrum precedes the third time point of the gastric antrum, the third time point of the gastric antrum precedes the fourth time point of the gastric antrum, and the fourth time point of the gastric antrum precedes the repositioning time point; The second time point at the gastric fundus and the first time point at the gastric body are the same time. The second time point of the gastric body and the first time point of the gastric antrum are the same time point, and the fourth time point of the gastric body and the fourth time point of the gastric fundus are the same time point; The first time difference is greater than the second time difference, and the second time difference is equal to the third time difference; wherein, the first time difference is the time difference between the first time point of the gastric fundus and the second time point of the gastric fundus, the second time difference is the time difference between the first time point of the gastric body and the second time point of the gastric body, and the third time difference is the time difference between the first time point of the gastric antrum and the second time point of the gastric antrum.

[0009] In some implementations, the fourth time difference is equal to the fifth time difference, and the fifth time difference is greater than the sixth time difference; wherein, the fourth time difference is the time difference between the second time point of the gastric fundus and the third time point of the gastric fundus, the fifth time difference is the time difference between the second time point of the gastric body and the third time point of the gastric body, and the sixth time difference is the time difference between the second time point of the gastric antrum and the third time point of the gastric antrum.

[0010] In some implementations, the eighth time difference is equal to the ninth time difference; wherein the eighth time difference is the time difference between the third time point of the gastric body and the fourth time point of the gastric fundus, and the ninth time difference is the time difference between the third time point of the gastric antrum and the fourth time point of the gastric antrum.

[0011] In some embodiments, the diastolic component includes: The functional part conforms to the curvature of the cross-sectional edge of the artificial stomach for surface contact with the artificial stomach; at least two functional parts are provided. The drive unit is used to drive the plurality of functional parts to move toward or away from the cross-sectional geometric center of the artificial stomach.

[0012] In some embodiments, the diastolic component further includes: The transmission unit includes a lead screw and a linkage rod; The driving component includes a drive motor; The transmission lead screw is connected to the drive end of the drive motor and can convert the rotation of the drive motor into reciprocating motion along the axis of the transmission lead screw. One end of the linkage rod is hinged to the functional part, and the other end is hinged to the transmission lead screw; The diastolic assembly further includes a fixing part for limiting the functional part, thereby causing the displacement direction of the functional part to be closer to or farther from the geometric center of the cross section of the artificial stomach.

[0013] This application provides a control method for an artificial stomach, including monitoring a start signal; upon detecting the start signal, controlling each of the driving components to drive the relaxation assembly according to a preset timing sequence, causing the corresponding part of the artificial stomach to contract or relax, so that the contents of the artificial stomach move regularly from the entrance direction to the exit direction. By changing the timing and interval of the movement of the relaxation assembly of the whole stomach, the pathological characteristics of delayed peristaltic wave transmission and disordered start sequence are simulated. Furthermore, by adjusting the interval between the contraction cessation time and the expansion start time, the abnormally prolonged interval between contraction and relaxation or the interruption of peristaltic waves under pathological conditions is replicated. Attached Figure Description

[0014] Figure 1 This is a schematic diagram of the overall process of a method for controlling an artificial stomach provided in an embodiment of this application; Figure 2 This is a schematic diagram of the basic timing-driven process of the gastric region in a control method for an artificial stomach provided in an embodiment of this application; Figure 3 This is a schematic diagram of the timing refinement driving process of the gastric fundus in a control method for an artificial stomach provided in an embodiment of this application; Figure 4 This is a schematic diagram of the timing refinement driving process of the stomach body in a control method for an artificial stomach provided in an embodiment of this application; Figure 5 This is a schematic diagram of the timing refinement drive process of the gastric antrum in a control method for an artificial stomach provided in an embodiment of this application; Figure 6 This is a schematic diagram of the fully partitioned precise timing drive process of an artificial stomach control method provided in an embodiment of this application; Figure 7 This is a schematic diagram of the overall structure of the bionic artificial stomach device provided in the embodiments of this application; Figure 8 This is a schematic diagram of the gastric region structure of the artificial stomach provided in the embodiments of this application; Figure 9 This is a schematic diagram of the overall structure of the diastolic component provided in the embodiments of this application.

[0015] Explanation of reference numerals in the attached drawings: 10, artificial stomach; 11, gastric fundus; 12, gastric body; 13, gastric antrum; 20, dilatation assembly; 21, functional part; 22, transmission screw; 23, linkage rod; 24, fixing part. Detailed Implementation

[0016] The embodiments of the technical solution of this application will now be described in detail with reference to the accompanying drawings. These embodiments are only used to more clearly illustrate the technical solution of this application and are therefore merely examples, and should not be used to limit the scope of protection of this application.

[0017] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application pertains; the terminology used herein is for the purpose of describing particular embodiments only and is not intended to limit the application; the terms “comprising” and “having”, and any variations thereof, in the specification, claims, and foregoing description of the drawings are intended to cover non-exclusive inclusion.

[0018] In the description of the embodiments of this application, technical terms such as "first" and "second" are used only to distinguish different objects and should not be construed as indicating or implying relative importance or implicitly specifying the number, specific order, or primary and secondary relationship of the indicated technical features. In the description of the embodiments of this application, "multiple" means two or more, unless otherwise explicitly defined.

[0019] In this document, the term "embodiment" means that a particular feature, structure, or characteristic described in connection with an embodiment may be included in at least one embodiment of this application. The appearance of this phrase in various places throughout the specification does not necessarily refer to the same embodiment, nor is it a separate or alternative embodiment mutually exclusive with other embodiments. It will be explicitly and implicitly understood by those skilled in the art that the embodiments described herein can be combined with other embodiments.

[0020] In the description of the embodiments in this application, the term "and / or" is merely a description of the relationship between related objects, indicating that three relationships can exist. For example, A and / or B can represent: A existing alone, A and B existing simultaneously, and B existing alone. Additionally, the character " / " in this document generally indicates that the preceding and following related objects have an "or" relationship.

[0021] In the description of the embodiments of this application, the term "multiple" refers to two or more (including two), similarly, "multiple sets" refers to two or more (including two sets), and "multiple pieces" refers to two or more (including two pieces).

[0022] In the description of the embodiments of this application, the technical terms "center," "longitudinal," "lateral," "length," "width," "thickness," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," "clockwise," "counterclockwise," "axial," "radial," and "circumferential" indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing the embodiments of this application and simplifying the description, and are not intended to indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on the embodiments of this application.

[0023] In the description of the embodiments of this application, unless otherwise expressly specified and limited, technical terms such as "installation," "connection," "joining," and "fixing" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components. For those skilled in the art, the specific meaning of the above terms in the embodiments of this application can be understood according to the specific circumstances.

[0024] To make the objectives, technical solutions, and advantages of this application clearer, the following detailed description is provided in conjunction with embodiments. It should be understood that the specific embodiments described herein are merely illustrative and not intended to limit the scope of this application.

[0025] Reference Figure 1 as well as Figures 7 to 9A control method for an artificial stomach 10, the artificial stomach 10 including multiple dilatation components 20 and multiple driving components, each driving component being used to drive the dilatation components 20 to move, the control method including: S101, Monitor the start signal; S102. When the start signal is detected, control each driving component to drive the relaxation component 20 according to the preset timing to make the corresponding part of the artificial stomach 10 contract or relax, so that the contents in the artificial stomach 10 move regularly from the entrance direction of the artificial stomach 10 to the exit direction of the artificial stomach 10.

[0026] Specifically, this control method is first implemented based on an artificial stomach 10, which is equipped with multiple relaxation components 20. The relaxation components 20 are devices that directly act on the wall of the artificial stomach 10, causing the stomach wall to contract or relax, in order to simulate gastric peristalsis.

[0027] Meanwhile, the diastolic component 20 is also driven by the driving component, which provides power to the diastolic component 20 to enable the diastolic component 20 to drive the stomach wall to contract or relax. The driving component has an independent control relationship with multiple diastolic components 20. This independent control relationship means that the driving component can ensure that the movement relationship between multiple diastolic components 20 does not interfere with each other, thereby independently controlling the start or stop time, direction, amplitude, and duration of the corresponding diastolic component 20's movement, thereby achieving differentiated timing drive to better simulate gastric peristalsis.

[0028] Based on the above device, this control method first includes monitoring the start signal. This means that the device monitors and identifies the start signal using a control unit. For example, the control unit may include a microcontroller, PLC, industrial controller, etc. The start signal can be set to any valid trigger signal that can be recognized by the controller, depending on the usage scenario. This includes, but is not limited to: electrical signals emitted by the operator pressing the start button through the human-machine interface, timed trigger commands from a preset program, trigger signals fed back by sensors after detecting the addition of contents to be digested into the artificial stomach 10, and running commands issued by a host computer. Only when the controller detects a valid start signal will it enter the subsequent drive execution process; if no valid signal is detected, it will remain in standby mode and will not execute any drive actions to avoid false triggering.

[0029] Upon detecting the drive signal, the control unit controls each drive component to drive the relaxation assembly 20 according to a preset timing sequence, causing the corresponding part of the artificial stomach 10 to contract or relax. This means the control unit sends control commands to the drive components that match the preset timing sequence. The preset timing sequence is a pre-edited and stored action schedule in the controller, specifying the action parameters for each drive component. Depending on the different settings of the drive components, this may include the start time of the action, the direction of the contraction or relaxation action, the duration of the action, the stop time of the action, the amplitude of the contraction or relaxation action, and the sequence, interval, and cycle of actions between different drive components. After receiving the control command corresponding to the timing sequence, each drive component drives the corresponding relaxation assembly 20 to perform a contraction or relaxation action. The action of the relaxation assembly 20 directly causes the corresponding part of the artificial stomach 10 bound to that assembly to synchronously contract or relax. For example, when the relaxation assembly 20 corresponding to the gastric fundus region receives a contraction command, it will cause the gastric fundus 11 position of the artificial stomach 10 to contract; when the relaxation assembly 20 corresponding to the gastric body region receives a relaxation command, it will cause the gastric body 12 position of the artificial stomach 10 to relax synchronously. Through the coordinated action of multiple driving components in a preset sequence, the artificial stomach 10 will undergo continuous contraction and relaxation deformation at various parts from the entrance to the exit, thereby simulating the peristaltic waves generated by the physiological peristalsis of the human stomach, which are continuously transmitted from the entrance (cardia) to the exit (pylorus). This propels the contents inside the artificial stomach 10 in a regular forward motion along the direction from the entrance to the exit, ultimately simulating the physiological functions of food mixing, digestion, and emptying in the human stomach.

[0030] For example, this control method is implemented based on a control unit, which includes an STM32 microcontroller, a stepper motor driver, a 220V to 5V power supply module, and a human-machine interface touch screen. The STM32 microcontroller is embedded inside the fixed base of the artificial stomach 10 device. The power supply module provides stable power to the microcontroller, driver, and drive motors. The STM32 microcontroller is electrically connected to the stepper motor driver through an I / O port, and the stepper motor driver is electrically connected to each drive motor in a one-to-one correspondence. The human-machine interface touch screen communicates with the STM32 microcontroller through a serial port and is used to send start signals and edit and modify preset timing parameters.

[0031] The S101 monitors the start signal, specifically including: the STM32 microcontroller continuously monitors the signals of the input port. When it receives the start electrical signal sent by the operator through the touch screen, the timed trigger command of the preset program, or the trigger signal fed back after the weight sensor detects the addition of the contents to be digested in the artificial stomach 10, it is determined that a valid start signal has been detected and the subsequent drive process is entered; when no valid start signal is detected, it always remains in standby state.

[0032] For example, the artificial stomach 10 is divided into a gastric fundus 11, a gastric body 12, and a gastric antrum 13, each of which is provided with at least one dilatation component 20. In S102, after the STM32 microcontroller detects a valid start signal, it sends a PWM control signal to the corresponding stepper motor driver according to a pre-stored preset timing sequence. After being converted into a high-voltage drive signal by the driver, the signal controls the corresponding drive motor to operate according to preset parameters, thereby driving the corresponding dilatation component 20 to perform contraction or relaxation actions. Through the sequential action of the dilatation components 20 in the gastric fundus 11, gastric body 12, and gastric antrum 13, a progressive peristaltic wave is formed from the inlet to the outlet, which propels the contents of the stomach toward the outlet in a regular manner.

[0033] An exemplary setting rule for the preset timing is that the total duration of a single peristaltic cycle is 15s-30s, the contraction start time of the gastric fundus 11 is 3s-8s earlier than that of the gastric body, the contraction start time of the gastric body 12 is 2s-5s earlier than that of the gastric antrum, the duration of contraction of each part matches the physiological function of the corresponding region, the duration of contraction of the gastric fundus 11 is longer than that of the gastric body 12 and the gastric antrum 13, and the duration of contraction of the gastric body 12 and the gastric antrum 13 is the same.

[0034] The pathological changes in insufficient gastric motility are not simply a decrease in the amplitude and force of gastric contractions, but more importantly, a disorder in the temporal transmission of peristaltic waves, abnormal transitions between contraction and relaxation phases, and loss of rhythmic coordination in regional peristalsis. Normal gastric emptying relies primarily on the gradual and orderly transmission of peristaltic waves from the fundus to the antrum. The magnitude of the squeezing force has a relatively smaller impact on the gastric emptying rate compared to the impact of disordered peristaltic wave transmission. For example, the typical characteristics of diabetic gastroparesis are delayed initiation of proximal fundal contractions and compensatory hyperactivity of distal antral contractions; the core manifestation of age-related degenerative gastric motility disorders is an abnormally prolonged interval between contraction and relaxation, and in severe cases, interruption of peristaltic wave transmission. By altering the timing and interval of the entire gastric relaxation component 20, the pathological characteristics of delayed peristaltic wave transmission and disordered initiation timing can be simulated. Furthermore, by adjusting the interval between the contraction cessation point and the expansion initiation point, the manifestations of abnormally prolonged contraction-relaxation intervals or interrupted peristaltic waves under pathological conditions can be replicated.

[0035] Compared to methods that only adjust compression amplitude and squeezing pressure, the timing control scheme of this application mainly considers the pathological characteristics of gastric pressure not weakening or increasing under rhythm disorder. It mainly studies the specific effects of timing control on content retention and delayed emptying in the pathological characteristics of rhythm disorder, and has a higher degree of realism under this pathological condition.

[0036] In some implementations, refer to Figure 2 as well as Figures 7 to 9 The artificial stomach 10 includes a fundus 11, a body 12, and an antrum 13; At least three dilator components 20 are provided, and at least one dilator component 20 is provided in the fundus 11, body 12 and antrum 13 of the stomach; Controlling the contraction or relaxation of each drive component according to a preset timing sequence includes: S201, At the first moment of the stomach fundus 11, the diastolic component 20 of the stomach fundus 11 is driven to contract; S202, at the first moment of the stomach body 12, the diastolic component 20 of the stomach body 12 is driven to contract; S203, at the first time point, drive the diastolic component 20 of the gastric antrum 13 to contract; S204. Drive the relaxation components 20 of the gastric fundus 11, gastric body 12 and gastric antrum 13 before the repositioning point to reposition the artificial stomach 10. Among them, the first time point of the gastric fundus 11 precedes the first time point of the gastric body 12, the first time point of the gastric body 12 precedes the first time point of the gastric antrum 13, and the first time point of the gastric antrum 13 precedes the repositioning time point.

[0037] Specifically, the artificial stomach 10 is divided into three regions: the fundus 11, the body 12, and the antrum 13. The fundus 11 is the entrance region near the cardia and is physiologically the initiation point of peristaltic waves. The fundus 11 mainly receives food entering through the esophagus and initially accommodates it. At the same time, it needs to contract preferentially to form initial squeezing force, close the cardia entrance, and prevent contents from flowing back into the esophagus.

[0038] The gastric body 12 is the middle region connecting the gastric fundus and the gastric antrum. It has a large area and a long range. If the corresponding gastric body 12 lacks the relaxation component 20, the initial squeezing force of the gastric fundus cannot be effectively transmitted to the gastric antrum, and the contents will remain in the middle region of the stomach, unable to form continuous directional propulsion. The antrum 13 is the exit region near the pylorus. It needs to contract to push the contents toward the pyloric exit. If the corresponding diastolic component 20 for the antrum 13 is missing, the artificial stomach 10 will have difficulty achieving effective emptying at the end. The contents will accumulate near the exit and cannot be stably discharged from the artificial stomach 10.

[0039] Based on this, at the preset first time point of the gastric fundus 11, the control unit sends a control command to the drive component corresponding to the gastric fundus 11, driving the relaxation component 20 of the gastric fundus 11 to perform a contraction action, causing the gastric fundus region at the entrance of the artificial stomach 10 to contract, forming an initial squeezing force on the contents of the stomach towards the outlet, and simultaneously closing the entrance of the artificial stomach 10. At a preset first time point of the gastric body 12, the control component sends a control command to the drive component corresponding to the gastric body 12, driving the relaxation component 20 of the gastric body 12 to perform a contraction action; wherein the first time point of the gastric body 12 is later than the first time point of the gastric fundus 11, so that the gastric fundus contracts first and the gastric body contracts later, transmitting the contents squeezed by the gastric fundus towards the gastric antrum, forming a propulsive force; At the preset first time point of the antrum 13, the control component sends a control command to the drive component corresponding to the antrum 13, driving the relaxation component 20 of the antrum 13 to perform a contraction action; the first time point of the antrum 13 is later than the first time point of the body 12. After the body completes the pushing action, the antrum 13 continues to contract, concentrating and squeezing the contents pushed by the body towards the outlet of the artificial stomach 10, completing the end pushing and emptying action of peristalsis in a single cycle; Before the preset reset time, the controller sends a reset command to the drive components of the three zones, driving the relaxation components 20 of the gastric fundus 11, gastric body 12, and gastric antrum 13 to perform relaxation actions, so that the entire artificial stomach 10 is restored to the initial relaxation state, thereby ending a single peristaltic cycle.

[0040] The conventional artificial stomach 10 only achieves zoned contraction and relaxation, resulting in poor simulation. This solution simulates the original physiological peristaltic rhythm of the human stomach through driving timing design, transmitting the signals unidirectionally and progressively along the stomach body towards the antrum and pylorus, thereby improving the biomimeticity of the artificial stomach 10's driving mechanism.

[0041] In some implementations, refer to Figure 3 as well as Figures 7 to 9 After the relaxation component 20 of the gastric fundus 11 is driven to contract at the first time point, controlling each driving component to contract or relax according to a preset timing sequence also includes: S301, Stop driving the diastolic component 20 of the gastric fundus 11 at the second time point; S302, at the third time point of the gastric fundus 11, drive the expansion of the dilatation component 20 of the gastric fundus 11, and at the fourth time point of the gastric fundus 11, stop the drive of the driving component on the dilatation component 20; The first time point of the gastric fundus 11 precedes the second time point of the gastric fundus 11, the second time point of the gastric fundus 11 precedes the third time point of the gastric fundus 11, the third time point of the gastric fundus 11 precedes the fourth time point of the gastric fundus 11, and the fourth time point of the gastric fundus 11 precedes the repositioning time point. The second time point of the gastric fundus 11 and the first time point of the gastric body 12 are at the same time.

[0042] Specifically, after S201, at the second time point of the gastric fundus 11, the control component simultaneously performs two actions: first, it sends a stop command to the gastric fundus 11 drive, causing the gastric fundus 11 relaxation component 20 to stop contracting and maintain its current contracted state; second, it sends a start command to the gastric body 12 drive, causing the gastric body 12 relaxation component 20 to begin contracting, continuing the squeezing action of the gastric fundus 11. At this time, the gastric fundus 11 remains contracted and closes the entrance, while the gastric body 12 begins to advance the contents, thereby allowing the gastric body 12 to uninterruptedly receive the squeezing kinetic energy of the gastric fundus 11, ensuring the continuity of the contents' advance.

[0043] In some implementations, refer to Figure 4 as well as Figures 7 to 9 After the gastric body 12 is driven to contract at the first time point, controlling each driving component to contract or relax according to a preset timing sequence further includes: S401, Stop the contraction of the diastolic component 20 of the gastric body 12 at the second time point; S402, at the third time point of the stomach body 12, the expansion component 20 of the stomach body 12 is driven to expand, and at the fourth time point of the stomach body 12, the driving member for the expansion component 20 is stopped. The first time point of the gastric body 12 precedes the second time point of the gastric body 12, the second time point of the gastric body 12 precedes the third time point of the gastric body 12, the third time point of the gastric body 12 precedes the fourth time point of the gastric body 12, and the fourth time point of the gastric body 12 precedes the repositioning time point. The second time point of the gastric body 12 and the first time point of the gastric antrum 13 are the same time point.

[0044] Specifically, at the second time point, the gastric body 12 stops contracting and remains in a contracted state, while the gastric antrum relaxation component 20 simultaneously begins to contract, receiving the squeezing propulsion force of the gastric body and performing end-stage pressurization and emptying. The second time point of the gastric body 12 is synchronized with the first time point of the gastric antrum 13, so that the gastric antrum immediately receives the squeezing kinetic energy of the gastric body, thereby forming a continuous movement from the gastric body to the gastric antrum, avoiding contraction intervals caused by time differences between the two, thus improving the simulation accuracy.

[0045] In some implementations, refer to Figure 5 as well as Figures 7 to 9 After the diastolic component 20 of the gastric antrum 13 contracts at the first time point, controlling each driving component to contract or relax according to a preset timing sequence further includes: S501, Stop the contraction of the diastolic component 20 of the gastric antrum 13 at the second time point; S502, at the third time point of the antral portion 13, the dilation component 20 of the gastric body portion 12 is driven to expand, and at the fourth time point of the antral portion 13, the driving force for the dilation component 20 is stopped. The first time point of the antral region 13 precedes the second time point of the antral region 13, the second time point of the antral region 13 precedes the third time point of the antral region 13, the third time point of the antral region 13 precedes the fourth time point of the antral region 13, and the fourth time point of the antral region 13 precedes the repositioning time point.

[0046] In some implementations, refer to Figures 6 to 9 Controlling the contraction or relaxation of each driving component according to a preset timing sequence includes: S601, at the first moment of the stomach fundus 11, drive the diastolic component 20 of the stomach fundus 11 to contract; S602, Stop driving the diastolic component 20 of the gastric fundus 11 at the second time point; S603, at the first moment of the stomach body 12, the diastolic component 20 of the stomach body 12 is driven to contract; S604, Stop driving the diastolic assembly 20 of the stomach body 12 at the second time point; S605, at the first time point of the gastric antrum 13, the diastolic component 20 of the gastric antrum 13 is driven to contract; S606, At the third time point of the gastric fundus 11, the diastolic component 20 of the gastric fundus 11 is driven to expand; S607. At the second time point of the gastric antrum 13, stop the contraction of the diastolic component 20 of the gastric antrum 13; S608, At the third time point, the diastolic component 20 of the gastric body 12 is driven to expand; S609, At the third time point of the gastric antrum 13, the dilation component 20 of the gastric body 12 is driven to expand; S610, at the fourth time point of the gastric fundus 11, stop the drive of the drive unit for the gastric fundus 11 dilation assembly 20; S611, at the fourth time point of the stomach body 12, stop the drive of the drive member on the stomach body 12 relaxation assembly 20; S612, at the fourth time point of the gastric antrum 13, stop the drive of the drive unit for the gastric antrum 13 relaxation assembly 20; The first time point of the gastric fundus 11 precedes the second time point of the gastric fundus 11, the second time point of the gastric fundus 11 precedes the third time point of the gastric fundus 11, the third time point of the gastric fundus 11 precedes the fourth time point of the gastric fundus 11, and the fourth time point of the gastric fundus 11 precedes the repositioning time point. The first time point of the gastric body 12 precedes the second time point of the gastric body 12, the second time point of the gastric body 12 precedes the third time point of the gastric body 12, the third time point of the gastric body 12 precedes the fourth time point of the gastric body 12, and the fourth time point of the gastric body 12 precedes the repositioning time point. The first time point of the antral portion 13 precedes the second time point of the antral portion 13, the second time point of the antral portion 13 precedes the third time point of the antral portion 13, the third time point of the antral portion 13 precedes the fourth time point of the antral portion 13, and the fourth time point of the antral portion 13 precedes the repositioning time point. The second time point of the gastric fundus 11 and the first time point of the gastric body 12 are the same time; The second time point of the gastric body 12 and the first time point of the gastric antrum 13 are the same time point; the fourth time point of the gastric body 12 and the fourth time point of the gastric fundus 11 are the same time point. The first time difference is greater than the second time difference, and the second time difference is equal to the third time difference; wherein, the first time difference is the time difference between the first time point of the gastric fundus 11 and the second time point of the gastric fundus 11, the second time difference is the time difference between the first time point of the gastric body 12 and the second time point of the gastric body 12, and the third time difference is the time difference between the first time point of the gastric antrum 13 and the second time point of the gastric antrum 13.

[0047] Specifically, at the first time point of the gastric fundus 11, the gastric fundus 11 relaxation component 20 begins to contract, achieving initial compression and closure of the inlet; then, at the second time point of the gastric fundus 11 (i.e., the first time point of the gastric body 12), the gastric fundus 11 stops contracting and remains in a contracted state; the gastric body 12 relaxation component 20 simultaneously begins to contract, receiving the compression propulsion force; At the second time point of the gastric body 12 (i.e., the first time point of the gastric antrum 13), the gastric body 12 stops contracting and remains in a contracted state; the gastric antrum 13 relaxation component 20 simultaneously begins to contract, receiving the squeezing propulsion force and applying end pressure. The second time point after the gastric body 12 is the third time point of the gastric fundus 11. At this time point, the gastric fundus 11 relaxation component 20 begins to actively expand and gradually restores its capacity. After the third time point of the gastric fundus 11, the second time point of the gastric antrum 13 occurs. At this time point, the gastric antrum 13 stops contracting and remains in a contracted state. The second time point after the antrum 13 is the third time point of the body 12. At this time point, the dilation component 20 of the body 12 begins to actively expand and gradually restore its capacity. After the third time point of the gastric body 12, the third time point of the gastric antrum 13 is reached. At this time point, the gastric antrum 13 relaxation component 20 begins to actively expand and gradually restore its capacity. The third time point after the antrum 13 is the fourth time point of the fundus 11, which is also the fourth time point of the body 12. At this time, the fundus 11 and the body 12 of the stomach stop expanding synchronously and maintain their current expansion state. The synchronous cessation of expansion of the fundus and body of the stomach can stabilize the volume of the upstream region of the stomach, thereby stabilizing the pressure environment in the stomach and avoiding pressure fluctuations from affecting the propulsion of contents. The third time point after the gastric antrum 13 is the fourth time point of the gastric antrum 13. At this time point, the gastric antrum 13 stops expanding and maintains its current expanded state. In this embodiment, the last point of a single loop is the reset point, and this point also serves as the starting point for the next loop.

[0048] Meanwhile, in this embodiment, the first time difference is greater than the second time difference, and the second time difference is equal to the third time difference; wherein, the first time difference is the time difference between the first time point of the gastric fundus 11 and the second time point of the gastric fundus 11, the second time difference is the time difference between the first time point of the gastric body 12 and the second time point of the gastric body 12, and the third time difference is the time difference between the first time point of the gastric antrum 13 and the second time point of the gastric antrum 13.

[0049] This means that this control method requires the duration of fundus contraction to be greater than the duration of body contraction and antral contraction, while the duration of body contraction and antral contraction should be equal.

[0050] This is because there are functional zones in the human stomach. The fundus is mainly responsible for receptive expansion and storing food, which requires a longer contraction and squeezing to slowly push the stored food into the stomach body. The stomach body and antrum are mainly responsible for peristalsis to grind food and push chyme into the pylorus. The physiological rhythms of the two are highly synchronized, and the duration of their contractions is consistent, which is more in line with the natural peristalsis pattern. This allows the device to drive the peristalsis more closely to the physiological peristalsis of the human body and improve the biomimicry of the simulation.

[0051] Meanwhile, this scheme defines four stages corresponding to the functional areas of the human stomach: the contraction stage, the contraction interval stage, the expansion stage, and the repositioning interval stage. In conventional technical schemes, the contraction and expansion stages are usually continuous cycles. For the simulation of insufficient gastric peristalsis, parameters such as compression amplitude and squeezing pressure are usually adjusted to simulate the state of gastric smooth muscle weakness. However, this does not take into account that gastric smooth muscle weakness can also lead to pathological interval prolongation, rhythmic cycle interruption, and peristaltic wave absence or cessation between the contraction and expansion states. This scheme defines the contraction stage, the contraction interval stage, the expansion stage, and the repositioning interval stage, and mainly relies on time point control and time difference control to simulate the normal physiological rhythm of gastric peristalsis and the pathological characteristics of gastric smooth muscle weakness. Thus, the pathological interval during the contraction and relaxation process is taken as the main simulation direction of gastric smooth muscle weakness, which improves the simulation realism of the artificial stomach 10 environment under this pathological condition.

[0052] In some implementations, the fourth time difference is equal to the fifth time difference, and the fifth time difference is greater than the sixth time difference; wherein, the fourth time difference is the time difference between the second time point of the gastric fundus 11 and the third time point of the gastric fundus 11, the fifth time difference is the time difference between the second time point of the gastric body 12 and the third time point of the gastric body 12, and the sixth time difference is the time difference between the second time point of the gastric antrum 13 and the third time point of the gastric antrum 13.

[0053] Specifically, the fourth time difference corresponds to the time difference between the cessation of contraction and the start of expansion of the gastric fundus 11, the fifth time difference corresponds to the time difference between the cessation of contraction and the start of expansion of the gastric body 12, and the sixth time difference corresponds to the time difference between the cessation of contraction and the start of expansion of the gastric antrum 13. The fourth time difference is equal to the fifth time difference and greater than the sixth time difference. That is, the interval between the gastric fundus 11 and the gastric body 12 is equal, while the interval between the gastric antrum 13 is shorter than the intervals of the former two. This constructs a pathological feature of delayed proximal gastric motility and relatively hyperactive distal gastric antrum motility under normal gastric peristalsis. This pathological feature is commonly seen in diabetic gastroparesis, idiopathic gastroparesis, and postprandial discomfort syndrome. This study aims to quantify and replicate the pathomechanical characteristics of proximal gastric motility insufficiency and distal antral hypermotility in functional dyspepsia, gastric electrical rhythm disorders, pyloric dysfunction-related gastric emptying abnormalities, and age-related degenerative gastric motility disorders. Distinguishing these characteristics from normal gastric physiology, a simulated pathomechanical model is constructed. By adjusting the physical quantities of the fourth, fifth, and sixth time differences, the correlation between the difference in expansion initiation time difference and gastric emptying rate, intragastric pressure, and food grinding efficiency is established, and relevant pathological thresholds are identified to investigate the mechanical pathogenesis of gastric motility disorders. Simultaneously, the sustained-release process of drugs in this pathological environment is studied to assist drug development, reduce reliance on animal experiments, and lower drug development costs.

[0054] In some implementations, the eighth time difference is equal to the ninth time difference; wherein the eighth time difference is the time difference between the third time point of the gastric body 12 and the fourth time point of the gastric fundus 11, and the ninth time difference is the time difference between the third time point of the gastric antrum 13 and the fourth time point of the gastric antrum 13.

[0055] Specifically, in normal gastric physiological movement, the time difference between the expansion and repositioning of the fundus, body, and antrum of the stomach exhibits a gradient difference. This achieves a coordinated rhythm of fundus receptivity, body peristalsis, and antral grinding and emptying. The seventh time difference refers to the time difference between the third time point of fundus 11 and the fourth time point of fundus 11. Since the third time point of fundus 11 precedes the third time point of body 12, and the fourth time point of fundus 11 and body 12 are the same time point, the seventh time difference must be greater than the eighth time difference. The eighth time difference equals the ninth time difference, which is the repositioning time difference between body 12 and antrum 13. Equally capable of simulating functional gastric motility disorders, gastroparesis, functional dyspepsia, obstructive gastric emptying, gastroesophageal reflux disease with gastric motility timing disorders, post-gastric surgery gastric motility disorders, and pyloric dysfunction-related gastric peristalsis rhythm disorders, which are mainly caused by abnormal rhythms of the antrum 13 and body 12 of the stomach, thus simulating the simulation gap of the bionic stomach model for the subdivided pathological subtypes in this field, providing an experimental environment for drugs and medical devices under these pathological conditions, and providing a quantitative timing reference standard for examinations such as electrogastrography, gastric emptying imaging, and gastric motility monitoring.

[0056] In some implementations, refer toFigures 7 to 9 The diastolic component 20 includes: Functional part 21, the functional part 21 is fitted with the arc of the cross-sectional edge of the artificial stomach 10 for surface contact with the artificial stomach 10; at least two functional parts 21 are provided; The driving component is used to drive multiple functional units 21 to produce movements that are closer to or further away from the cross-sectional geometric center of the artificial stomach 10.

[0057] Specifically, the relaxation component 20 includes a functional part 21 for directly contacting the outer wall of the artificial stomach 10 and transmitting driving force. The shape of the functional part 21 is matched with the curvature of the cross-section edge of the corresponding position of the artificial stomach 10, thereby achieving a surface contact fit with the outer wall of the artificial stomach 10.

[0058] In a single-unit diastolic assembly 20, at least two functional units 21 are provided, which can be distributed circumferentially around the cross section of the artificial stomach 10 to form a circumferential covering layout of the artificial stomach 10. Under the drive of the driving component, they can generate mutual opposing movement or opposite movement, thereby realizing the contraction and rebound reset of the artificial stomach 10.

[0059] For example, the structure of the diastolic component 20 is matched with the execution of the preset timing sequence. The speed and number of rotations of the drive motor are linearly related to the displacement of the functional unit 21. For every rotation of the drive motor, the slider of the transmission screw 22 moves axially by 2mm, corresponding to a radial displacement of 1mm for the functional unit 21. The contraction / diastolic amplitude is precisely controlled by controlling the number of rotations of the drive motor, the direction of contraction or diastolic action is controlled by controlling the forward and reverse rotation of the motor, and the start and stop times of the motor are precisely matched to the requirements of the preset timing sequence.

[0060] In some implementations, refer to Figures 7 to 9 The diastolic component 20 also includes: The transmission part includes a lead screw 22 and a linkage rod 23; The driving components include the drive motor; The transmission screw 22 is connected to the drive end of the drive motor and can convert the rotation of the drive motor into reciprocating motion along the axis of the transmission screw 22. One end of the linkage rod 23 is hinged to the functional part 21, and the other end is hinged to the transmission screw 22; The diastolic assembly 20 also includes a fixing part 24, which limits the functional part 21 so that the displacement direction of the functional part 21 is closer to or farther from the geometric center of the cross section of the artificial stomach 10.

[0061] Specifically, the transmission unit is a connection structure that connects the drive unit and the functional unit 21, used to transmit the rotational power of the drive motor to the functional unit 21 in a linear motion, including a transmission screw 22 and a linkage rod 23. Meanwhile, in this embodiment, the drive unit includes a drive motor, which can output controllable rotational motion in both forward and reverse directions, and can independently control and adjust the direction of rotation, speed, number of revolutions, and start / stop timing, thereby controlling the direction of motion, speed, stroke range, and start / stop sequence of the functional unit 21, and thus realizing the adjustment and control of time points and time differences in different stages.

[0062] One end of the transmission screw 22 is engaged with the drive end of the drive motor, and can rotate synchronously and coaxially with the output shaft of the drive motor to convert the rotational motion of the drive motor into its own linear reciprocating motion along the axial direction.

[0063] The linkage 23 is hinged to the transmission part, and its two ends are respectively connected to the functional part 21 and the linear motion end of the transmission screw 22 through a rotatable hinge structure. This converts the axial linear motion of the transmission screw 22 into the radial motion of the functional part 21 toward or away from the geometric center of the cross section of the artificial stomach 10. At the same time, the hinge structure adapts to the angle changes during the motion process.

[0064] The fixing part 24 is used to rigidly constrain the motion freedom of the functional part 21, retaining only the radial displacement freedom of the functional part 21 along the cross section of the artificial stomach 10, and restricting other directions such as swinging, deflection, and axial movement, so that the motion path and action direction of the functional part 21 are controllable.

[0065] For example, refer to Figures 7 to 9 The fixing part 24 includes a slide groove disposed on the functional part 21 and a fixing plate. The fixing plate is provided with a slider for cooperating with the slide groove. The slider can slide in the slide groove of the functional part 21 and limit the functional part 21 through the slide groove.

[0066] After receiving the contraction control command, the drive motor outputs rotational motion in the corresponding direction, driving the transmission screw 22 to move in its axial direction. During this reciprocating motion, it drives one end of the linkage rod 23 to move synchronously along the screw axis. The linkage rod 23 converts the axial displacement into radial thrust through the hinge structure, pushing the functional part 21 along the path defined by the fixed part 24 towards the geometric center of the cross section of the artificial stomach 10, and finally realizing the contraction action of the corresponding area of ​​the artificial stomach 10.

[0067] After receiving the relaxation control command, the drive motor outputs a reverse rotation motion, which drives the functional part 21 to move backward and reset along the path defined by the fixed part 24, away from the geometric center of the cross section of the artificial stomach 10, through the transmission screw 22 and the linkage rod 23, ultimately realizing the relaxation action of the corresponding area of ​​the artificial stomach 10.

[0068] In some embodiments, the device used in this control method is further provided with a silicone gastric cardia fixation module and a silicone gastric pyloric end fixation module for fixing the position of the artificial stomach 10. Exemplarily, the silicone gastric cardia fixation module and the silicone gastric pyloric end fixation module include a fixing post and a fixing ring. The fixing ring is sleeved on the artificial stomach 10, and the fixing ring is fixed to the ground, tabletop, or other types of fixed base surface by the fixing post.

[0069] In some embodiments, the device used in this control method further includes a control module, which includes an STM32 microcontroller, a stepper motor driver, and a 220V to 5V power supply module. The STM32 microcontroller is embedded inside the device's mounting base, and the power supply module provides it with a stable power supply. The STM32 microcontroller is electrically connected to the stepper motor driver via a circuit, and the stepper motor driver is electrically connected to three stepper motors. The STM32 microcontroller uses an interrupt-driven approach, generates a time base through a timer, outputs a PWM control signal according to preset control logic, and converts it into a high-voltage drive signal by the stepper motor driver to drive the motor. At the same time, the STM32 microcontroller receives feedback signals to achieve closed-loop control. The timing control logic of the three stepper motors is as follows: Motor 1 (driven by the gastric fundus 11) starts immediately after the system starts, and its action logic is to rotate counterclockwise for 6 seconds, stop for 4 seconds, rotate clockwise for 6 seconds, and stop for 4 seconds; Motor 2 (driven by the gastric body 12) starts after a delay of 6 seconds, and its action logic is to rotate counterclockwise for 3 seconds, stop for 4 seconds, rotate clockwise for 3 seconds, and stop for 4 seconds; Motor 3 (driven by the gastric antrum 13) starts after a delay of 9 seconds, and its action logic is to rotate counterclockwise for 3 seconds, stop for 2 seconds, rotate clockwise for 3 seconds, and stop for 3 seconds, completing 3 complete peristaltic cycles within 60 seconds.

[0070] The above description is merely a specific embodiment of this application, but the scope of protection of this application is not limited thereto. Any modifications, equivalent substitutions, and improvements made by those skilled in the art within the scope of the technology disclosed in this application, and within the spirit and principles of this application, should be included within the scope of protection of this application.

[0071] It should be noted that this application is not limited to the above-described embodiments. The above embodiments are merely examples, and any embodiments with the same structure and effect as the technical concept within the scope of this application are included in the technical scope of this application. Furthermore, various modifications that can be conceived by those skilled in the art to the embodiments, and other ways of constructing by combining some of the constituent elements of the embodiments, without departing from the spirit of this application, are also included in the scope of this application.

Claims

1. A method for controlling an artificial stomach, characterized in that, The artificial stomach includes multiple relaxation components and multiple actuators, each actuator being used to drive the movement of the relaxation components, and the control method includes: Monitor the start signal; When the start signal is detected, each of the driving components is controlled to drive the relaxation component according to a preset timing sequence, so that the corresponding part of the artificial stomach contracts or relaxes, so that the contents of the artificial stomach move regularly from the entrance of the artificial stomach to the exit of the artificial stomach.

2. The method for controlling an artificial stomach according to claim 1, characterized in that, The artificial stomach includes a fundus, a body, and an antrum. At least three dilator components are provided, and at least one dilator component is provided in the fundus, body and antrum of the stomach; The control of each of the driving components to contract or relax according to a preset timing sequence includes: At a first point in time, the diastolic components of the gastric fundus are driven to contract; At a first point in time, the diastolic component of the gastric body is driven to contract. At a first point in time, the diastolic component of the gastric antrum is driven to contract. Before the repositioning point, the relaxation components of the gastric fundus, gastric body, and gastric antrum are driven to reposition the artificial stomach; Specifically, the first time point of the gastric fundus precedes the first time point of the gastric body, the first time point of the gastric body precedes the first time point of the gastric antrum, and the first time point of the gastric antrum precedes the repositioning time point.

3. The method for controlling an artificial stomach according to claim 2, characterized in that, After the diastolic component at the gastric fundus contracts at a first time point, controlling each of the driving components to contract or relax according to a preset timing sequence further includes: At a second time point at the gastric fundus, the actuation of the gastric fundus diastolic assembly is stopped; At a third time point at the gastric fundus, the dilatation component at the gastric fundus is driven to expand, and at a fourth time point at the gastric fundus, the driving force on the dilatation component is stopped. The first time point of the gastric fundus precedes the second time point of the gastric fundus, the second time point of the gastric fundus precedes the third time point of the gastric fundus, the third time point of the gastric fundus precedes the fourth time point of the gastric fundus, and the fourth time point of the gastric fundus precedes the repositioning time point; The second time point at the gastric fundus and the first time point at the gastric body are the same time.

4. The method for controlling an artificial stomach according to claim 2, characterized in that, After the relaxation component of the stomach body is driven to contract at a first time point in the stomach body, the control of each of the driving components to contract or relax according to a preset timing sequence further includes: At the second time point in the gastric body, the contraction of the diastolic assembly of the gastric body is stopped; At a third time point in the stomach body, the dilation component of the stomach body is driven to expand, and at a fourth time point in the stomach body, the driving force on the dilation component is stopped. The first time point of the stomach body precedes the second time point of the stomach body, the second time point of the stomach body precedes the third time point of the stomach body, the third time point of the stomach body precedes the fourth time point of the stomach body, and the fourth time point of the stomach body precedes the repositioning time point; The second time point of the gastric body and the first time point of the gastric antrum are the same time point.

5. The method for controlling an artificial stomach according to claim 2, characterized in that, After the diastolic component of the gastric antrum is driven to contract at a first time point in the gastric antrum, the control of each of the driving components to contract or relax according to a preset timing sequence further includes: The contraction of the diastolic component in the antrum is stopped at the second time point in the gastric antrum; At the third time point in the antrum, the dilation component of the gastric body is driven to expand, and at the fourth time point in the antrum, the driving force on the dilation component is stopped. The first time point of the gastric antrum precedes the second time point of the gastric antrum, the second time point of the gastric antrum precedes the third time point of the gastric antrum, the third time point of the gastric antrum precedes the fourth time point of the gastric antrum, and the fourth time point of the gastric antrum precedes the repositioning time point.

6. The method for controlling an artificial stomach according to claim 2, characterized in that, The control of each of the driving components to contract or relax according to a preset timing sequence includes: At a first point in time, the diastolic components of the gastric fundus are driven to contract; The actuation of the dilatation component at the gastric fundus is stopped at a second time point; At a first point in time, the diastolic component of the gastric body is driven to contract. At the second time point in the gastric body, the driving of the gastric body's dilation component is stopped; At a first point in time, the diastolic component of the gastric antrum is driven to contract. At a third time point, the dilatational component of the gastric fundus is driven to expand; The contraction of the diastolic component in the antrum is stopped at the second time point in the gastric antrum; At a third time point in the gastric body, the diastolic component of the gastric body is driven to expand. At the third time point in the antrum, the dilator of the gastric body is driven to expand; At the fourth time point at the gastric fundus, the actuation of the actuation component for the gastric fundus relaxation assembly is stopped; At the fourth time point in the gastric body, the driving force for the gastric body relaxation assembly is stopped; At the fourth time point in the antrum, the drive of the actuator on the antrum dilator assembly is stopped; The first time point of the gastric fundus precedes the second time point of the gastric fundus, the second time point of the gastric fundus precedes the third time point of the gastric fundus, the third time point of the gastric fundus precedes the fourth time point of the gastric fundus, and the fourth time point of the gastric fundus precedes the repositioning time point; The first time point of the stomach body precedes the second time point of the stomach body, the second time point of the stomach body precedes the third time point of the stomach body, the third time point of the stomach body precedes the fourth time point of the stomach body, and the fourth time point of the stomach body precedes the repositioning time point; The first time point of the gastric antrum precedes the second time point of the gastric antrum, the second time point of the gastric antrum precedes the third time point of the gastric antrum, the third time point of the gastric antrum precedes the fourth time point of the gastric antrum, and the fourth time point of the gastric antrum precedes the repositioning time point; The second time point at the gastric fundus and the first time point at the gastric body are the same time. The second time point of the gastric body and the first time point of the gastric antrum are the same time point, and the fourth time point of the gastric body and the fourth time point of the gastric fundus are the same time point; The first time difference is greater than the second time difference, and the second time difference is equal to the third time difference; wherein, the first time difference is the time difference between the first time point of the gastric fundus and the second time point of the gastric fundus, the second time difference is the time difference between the first time point of the gastric body and the second time point of the gastric body, and the third time difference is the time difference between the first time point of the gastric antrum and the second time point of the gastric antrum.

7. The method for controlling an artificial stomach according to claim 6, characterized in that, The fourth time difference is equal to the fifth time difference, and the fifth time difference is greater than the sixth time difference; wherein, the fourth time difference is the time difference between the second time point of the gastric fundus and the third time point of the gastric fundus, the fifth time difference is the time difference between the second time point of the gastric body and the third time point of the gastric body, and the sixth time difference is the time difference between the second time point of the gastric antrum and the third time point of the gastric antrum.

8. The method for controlling an artificial stomach according to claim 6, characterized in that, The eighth time difference is equal to the ninth time difference; wherein, the eighth time difference is the time difference between the third time point of the gastric body and the fourth time point of the gastric fundus, and the ninth time difference is the time difference between the third time point of the gastric antrum and the fourth time point of the gastric antrum.

9. The method for controlling an artificial stomach according to claim 1, characterized in that, The diastolic component includes: The functional part conforms to the curvature of the cross-sectional edge of the artificial stomach for surface contact with the artificial stomach; at least two functional parts are provided. The drive unit is used to drive the plurality of functional parts to move toward or away from the cross-sectional geometric center of the artificial stomach.

10. The method for controlling an artificial stomach according to claim 9, characterized in that, The diastolic component also includes: The transmission unit includes a lead screw and a linkage rod; The driving component includes a drive motor; The transmission lead screw is connected to the drive end of the drive motor and can convert the rotation of the drive motor into reciprocating motion along the axis of the transmission lead screw. One end of the linkage rod is hinged to the functional part, and the other end is hinged to the transmission lead screw; The diastolic assembly further includes a fixing part for limiting the functional part, thereby causing the displacement direction of the functional part to be closer to or farther from the geometric center of the cross section of the artificial stomach.

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