A recombinant collagen dressing and a preparation method thereof

The modified substrate was prepared by mixing C mixture with nonwoven fabric to form a surface wrinkled structure, which solved the problem of tightness and breakage of medical dressings on the skin surface caused by solvent evaporation, and achieved uniformity and mechanical stability of the dressing effect.

CN122208809APending Publication Date: 2026-06-16JIANGSU JIAAO MEDICAL TECH CO LTD
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Patent Information

Authority / Receiving Office
CN ยท China
Patent Type
Applications(China)
Current Assignee / Owner
JIANGSU JIAAO MEDICAL TECH CO LTD
Filing Date
2026-03-17
Publication Date
2026-06-16

AI Technical Summary

Technical Problem

Existing medical dressings cause tightness on the skin surface due to solvent evaporation, and the breakage of dressing components leads to uneven application. There is a lack of effective mechanisms to solve the compatibility and comfort issues between dressings and the skin.

Method used

Modified substrates are prepared by mixing C mixture with nonwoven fabric. During the evaporation process, a surface wrinkled structure is formed. The wrinkle size is controlled by temperature gradient and nano-functional additives to form surface wrinkles that adapt to skin stretching and bending, thus solving the problems of dressing tightness and breakage.

Benefits of technology

The dressing was designed to prevent tightness on the skin surface due to solvent evaporation and ensure the uniformity of the dressing effect without breakage of the dressing components. The mechanical stability and durability of the modified substrate were verified through cyclic stretching-reset testing.

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Abstract

The application discloses a preparation method of a recombinant collagen dressing and belongs to the technical field of medical dressings. The method comprises the following steps: preparing a hyaluronic acid aqueous solution and a collagen A solution, filtering and defoaming the two solutions respectively, and sterilizing the two solutions by high-temperature steam; filling the two solutions into different cavities of a mask bag respectively, and sealing the mask bag by nitrogen; placing C mixed solution and degradable non-woven fabric sterilized by high temperature and ultraviolet rays on a heating mold, and heating and evaporating the C mixed solution and the non-woven fabric to obtain a modified substrate with a surface wrinkle structure. The modified substrate is prepared by mixing the C mixed solution and the non-woven fabric, and the surface wrinkle structure is formed in the evaporation process, so that the tightness problem caused by solvent evaporation after the dressing is applied on the skin surface and the problem that the dressing components are broken to cause uneven application effect are effectively solved. The modified substrate can still maintain the surface wrinkle structure after being cyclically stretched and reset for 100 times, and the tensile strength retention rate reaches more than 95%, which proves the mechanical stability and durability of the wrinkle structure.
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