A brain-computer interface-oriented neural perturbation tACS sleep brain network individualized closed-loop regulation method and system

By constructing a fusion brain functional connectivity matrix and a Transformer neurodynamic prediction model, and optimizing tACS stimulation parameters, the problem of individual differences and directional information flow being difficult to characterize in existing technologies was solved, realizing individualized and interpretable sleep brain network regulation and improving sleep memory consolidation.

CN122399247APending Publication Date: 2026-07-17CHONGQING UNIV OF POSTS & TELECOMM
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
CHONGQING UNIV OF POSTS & TELECOMM
Filing Date
2026-06-11
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Existing tACS sleep regulation protocols fail to account for individual differences, resulting in unstable stimulation effects, a lack of interpretable parameters, and difficulty in achieving individualized and dynamic adjustments. Traditional sleep EEG analysis cannot characterize the directional causal relationship between excitation and inhibition information flow.

Method used

We construct a personalized closed-loop modulation method for the tACS sleep brain network based on brain-computer interfaces. By acquiring EEG data and cognitive task behavior data from the entire night's sleep, we construct a fusion brain function connectivity matrix and optimize stimulation parameters using the Transformer neurodynamic prediction model to achieve individualized neuromodulation.

Benefits of technology

It achieves individualized neuromodulation, improves the scientific validity and interpretability of stimulation parameters, and can dynamically adjust stimulation according to the real-time brain network state, thereby enhancing the consolidation effect of sleep memory.

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Abstract

本发明涉及一种面向脑机接口的神经扰动tACS睡眠脑网络个性化闭环调控方法及系统,属于脑机接口领域。针对现有tACS睡眠调控策略存在的刺激参数固定、个体差异适配不足、缺乏兴奋抑制定向信息流量化及闭环反馈机制的问题,本发明首先获取全夜睡眠脑电数据与认知行为数据,构建融合脑功能连接矩阵并提取兴奋抑制定向信息流特征,识别记忆巩固低获益对象。随后基于Transformer神经动力学预测模型,通过梯度反演优化生成个体化tACS刺激参数,并输入闭环反馈系统根据实时脑网络状态动态调整刺激策略。本发明实现了睡眠记忆巩固的个体化神经调控,提升了刺激方案的有效性,解决了传统方法效果不稳定及难以动态调整的问题。
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