Compositions with nerve regeneration applications

JP2023532557A5Inactive Publication Date: 2026-06-22GRIFOLS WORLDWIDE OPERATIONS
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Patent Information

Authority / Receiving Office
JP · JP
Patent Type
Applications
Current Assignee / Owner
GRIFOLS WORLDWIDE OPERATIONS
Filing Date
2021-07-07
Publication Date
2026-06-22
Estimated Expiration
Not applicable · inactive patent

AI Technical Summary

Technical Problem

Current treatments for neurodegenerative diseases such as amyotrophic lateral sclerosis, Huntington's disease, Alzheimer's disease, and Parkinson's disease primarily focus on symptom management and neuroprotection, lacking therapies that can cure or reverse neuronal damage.

Method used

Administration of transferrin and lactoferrin, either wild-type or recombinant variants, with low iron saturation, to promote neuronal proliferation and differentiation, enhancing the body's nerve regeneration and repair mechanisms.

Benefits of technology

Transferrin and lactoferrin stimulate neuronal development by promoting the generation of new neurons, potentially reversing neuronal damage and improving neurological function in patients with neurodegenerative diseases.

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Abstract

Disclosed herein is a pharmaceutical composition containing transferrin or lactoferrin for use in promoting or inducing the generation of new nerve cells in patients suffering from neurodegenerative events. Neurodegenerative events may be caused by neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, Huntington's disease, or amyotrophic lateral sclerosis. Ideally, the transferrin and / or lactoferrin has low iron saturation.
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