Medium composition for promoting muscle cell differentiation comprising apigenin as active ingredient

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Apigenin-based culture medium composition enhances muscle cell differentiation, addressing the inefficiencies of serum-based cultured meat production by increasing activity and reducing costs.

WO2026134811A1PCT designated stage Publication Date: 2026-06-25RES COOPERATION FOUND OF YEUNGNAM UNIV

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Patent Information

Authority / Receiving Office: WO · WO
Patent Type: Applications
Current Assignee / Owner: RES COOPERATION FOUND OF YEUNGNAM UNIV
Filing Date: 2025-12-01
Publication Date: 2026-06-25

Application Information

Patent Timeline

01 Dec 2025

Application

25 Jun 2026

Publication

WO2026134811A1

IPC: C12N5/077; A23K20/121; A23L13/00

AI Tagging

Application Domain

Skeletal/connective tissue cells Accessory food factors

Technology Topics

Cultured meatApigetrin

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AI Technical Summary

Technical Problem

Current methods for producing cultured meat are costly and time-consuming due to the use of animal-derived serum, which is unethical and environmentally unfriendly, and serum-free media have limited applicability and high costs.

Method used

A culture medium composition containing apigenin as an active ingredient to promote muscle cell differentiation, which enhances the differentiation process and reduces the need for serum.

Benefits of technology

Apigenin effectively promotes muscle cell differentiation by increasing creatine kinase activity, reducing reactive oxygen species, and regulating muscle-specific marker expression, thereby improving the efficiency and reducing costs in cultured meat production.

✦ Generated by Eureka AI based on patent content.

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Abstract

The present invention relates to a medium composition for promoting muscle cell differentiation, the medium composition comprising apigenin as an active ingredient. It was confirmed that apigenin promotes the differentiation of muscle cells through regulation of the expression of muscle-specific markers and the promotion of creatine kinase activity, and thus the medium composition can be effectively used as a composition for promoting muscle cell differentiation or producing cultured meat.

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