Preparation method for 2-chloro-5-iodobenzoic acid

By preparing 2-chloro-5-iodobenzoic acid from cheap o-chlorobenzoic acid through nitration, reduction and diazotization iodo reactions, the problems of complex production methods and high cost in the existing technology are solved, and an efficient and suitable method is achieved. Preparation method for industrial production.

CN106748721AActive Publication Date: 2017-05-31SHANDONG BOYUAN PHARM CO LTD
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Patent Information

Application Number
CN201611010716.5
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2016-11-17
Publication Date
2017-05-31
Estimated Expiration
2036-11-17

AI Technical Summary

Technical Problem

The existing production method of 2-chloro-5-iodobenzoic acid is complex in operation, has high production cost, long reaction steps, low product yield, and is not suitable for industrial production.

Method used

Cheap o-chlorobenzoic acid is used as the starting material, and 2-chloro-5-iodobenzoic acid is obtained through nitration, reduction and diazotization iodo reactions, which shortens the reaction steps and improves the yield.

Benefits of technology

The production process is simplified, the cost is reduced, the overall yield and purity of the product are improved, and it is suitable for industrial production.

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Abstract

The invention discloses a preparation method for 2-chloro-5-iodobenzoic acid. The preparation method is characterized in that cheap o-chlorobenzoic acid is taken as a starting material to obtain 2-chloro-5-iodobenzoic acid through nitration, reduction and diazotization iodination. The method shortens reaction steps, increases the yield and is suitable for industrial production.
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