A small animal aseptic transfer device

Abstract

The present invention relates to the technical field of mechanical seals, and in particular to a small animal aseptic transfer device, which includes an outer transfer cavity and an inner transfer cavity located in the outer transfer cavity. The inner transfer cavity includes an inner tube, a carrier for carrying living things, and an inner end cover. The inner transfer cavity further includes an inner tube adapter fixedly connected to one end of the inner tube, a pressing block, and a handle for fixing the pressing block. A replaceable semi-permeable filter paper is provided between the pressing block and the inner tube adapter. Through the replaceable semi-permeable filter paper, the small animal aseptic transfer device has the beneficial effects of simple structure, reusable, and cost-saving.

Description

Technical Field

[0001] The present invention relates to the technical field of mechanical seals, and in particular to a small animal aseptic transfer device. Background Art

[0002] In medical experimental research, there are corresponding cleanliness requirements for different types of small animals used in experiments. For animals such as nude mice, a special small animal aseptic transfer device is required during the transportation process.

[0003] Please refer to Figure 1 , the Chinese utility model patent with the publication number CN206633045U discloses a glove box seal transfer device, which is characterized in that: it includes a transfer device seat, a chamber door, a container body and a container cover. The transfer device seat is circular and is fixedly installed on the inner wall of the glove box chamber through a fixing ring. A rotating ring is installed in the guide groove on the transfer device seat, and a plurality of pressing blocks are evenly installed on the rotating ring. Each pressing block is fixedly equipped with a ball bearing through a rotating shaft, and the ball bearing is installed in the guide groove on the rotating ring. A plurality of stoppers for cooperating with the pressing shaft are evenly installed on the transfer device seat. A handle is installed on the outside of the rotating ring, a pin is installed on the handle, a spring is provided at the inner end of the pin, and a plurality of rotating ring openings for cooperating with the pressing shaft are provided on the rotating ring; the chamber door is installed on the transfer device seat through a hinge, and a clamping plate for coupling with the container cover is provided on the chamber door. A plurality of pressing shafts are evenly installed on the outer edge of the chamber door through pressing pins, and a transfer device clamping pin for limiting the position when the container body rotates is also provided on the chamber door; the container cover and the container body are buckled together. A container flange is installed on the container cover, an inner lip seal and an outer lip seal are respectively installed on the inner side and the outer side of the container flange. A ball bearing is installed around the container flange through a clamping shaft. A container cover clamping pin for connecting with the container flange and playing a limiting role is installed on the container cover, and a tooth buckle for connecting with the chamber door is provided on the container cover.

[0004] Please refer to Figure 2 , the Chinese invention patent with the publication number CN208851644U discloses a disposable sterilized endoscope transfer box, which is characterized in that it includes a box body, a box cover and a fixing block. An inner cavity is provided in the box body. The upper end of the rear part of the box body is hinged with a box cover that matches it. A fixing device that can fixedly install the two together is provided at the front part of the box body and the rear part of the box cover; three fixing blocks are spaced in the inner cavity. The fixing block provided at the front left part in the inner cavity is the left fixing block, the fixing block provided in the center of the inner cavity is the middle fixing block, and the fixing block provided at the rear right part in the inner cavity is the right fixing block.

[0005] The transfer devices in the prior art cannot be reused or disassembled, resulting in the defect of high use cost. Summary of the Invention

[0006] The object of the present invention is to provide a small animal aseptic transfer device with a simple structure, which can be reused and saves costs.

[0007] To achieve the above advantages, the small animal aseptic transfer device provided by the present invention includes an outer transfer cavity and an inner transfer cavity located in the outer transfer cavity. The inner transfer cavity includes an inner tube, a support for carrying living things, and an inner end cap. The inner transfer cavity further includes an inner tube adapter fixedly connected to one end of the inner tube, a pressing block, and a handle for fixing the pressing block. A replaceable semi-permeable filter paper is provided between the pressing block and the inner tube adapter.

[0008] In one embodiment of the present invention, the outer transfer cavity includes an outer tube, a first outer end cap, a second outer end cap, and a plurality of screw rods. The first outer end cap and the second outer end cap are respectively located at both ends of the outer tube, and the first outer end cap and the second outer end cap are connected and fixed to the outer tube through the plurality of screw rods.

[0009] In one embodiment of the present invention, the first outer end cap and the second outer end cap are both provided with limiting rings. Limiting grooves corresponding to the limiting rings are respectively provided at both ends of the outer tube, and a first sealing ring in contact with the limiting grooves is provided on the limiting rings.

[0010] In one embodiment of the present invention, the pressing block is provided with a plurality of filter holes, and the handle is provided with air holes corresponding to the filter holes.

[0011] In one embodiment of the present invention, the support is threadedly connected to the inner tube. The support includes a connecting block fixed to the end of the inner tube and an arc-shaped plate extending into the inner tube. The connecting block is provided with a through hole.

[0012] In one embodiment of the present invention, the second outer end cap is provided with an air inlet nozzle, and the inner end cap is provided with an air outlet nozzle corresponding to the air inlet nozzle.

[0013] In one embodiment of the present invention, the inner tube adapter includes a fixed section fixedly connected to the end of the inner tube, a transition section for accommodating part of the air outlet nozzle, and a connecting section detachably connected to the end of the outer tube.

[0014] In one embodiment of the present invention, the connecting section is provided with a second sealing ring in contact with the inner wall of the outer tube.

[0015] In one embodiment of the present invention, the connecting section is provided with an annular groove for accommodating the semi-permeable filter paper.

[0016] In one embodiment of the present invention, the inner tube and the inner end cap are connected and fixed by bolts, and a third sealing ring is provided between the inner end cap and the inner tube.

[0017] In the present invention, through the replaceable semi-permeable filter paper, the small animal sterile transfer device has the beneficial effects of simple structure, reusability, and cost savings. Description of the Drawings

[0018] Figure 1 The figure shows a schematic structural diagram of a glove box sealing transfer device of the prior art.

[0019] Figure 2 The figure shows a schematic structural diagram of a disposable sterilized endoscope transfer box of the prior art.

[0020] Figure 3 The figure shows a schematic structural diagram of the small animal sterile transfer device according to the first embodiment of the present invention.

[0021] Figure 4 The figure shows Figure 3 an exploded view of the inner transfer cavity of the small animal sterile transfer device.

[0022] Figure 5 The figure shows Figure 3 a sectional view of the small animal sterile transfer device.

[0023] Figure 6 The figure shows Figure 5 a partial enlarged view of the small animal sterile transfer device at position A.

[0024] Figure 7 The figure shows Figure 3 a schematic structural diagram of the first outer end cover of the small animal sterile transfer device.

[0025] Figure 8 The figure shows a sectional view of the small animal sterile transfer device according to the third embodiment of the present invention.

[0026] Figure 9 The figure shows a right view of the small animal sterile transfer device according to the fourth embodiment of the present invention. Detailed Description of the Invention

[0027] To further elaborate on the technical means and effects adopted by the present invention to achieve the intended invention purpose, the following, in conjunction with the accompanying drawings and preferred embodiments, details the specific implementation manners, structures, features, and their effects according to the present invention as follows.

[0028] Please refer to Figure 3 , Figure 4, the small animal sterile transfer device of the first embodiment of the present invention includes an outer transfer cavity 1, and an inner transfer cavity 2 located inside the outer transfer cavity 1 and detachably connected to the outer transfer cavity 1. The inner transfer cavity 2 includes an inner tube 21, a carrier 22 for carrying living things, an inner end cover 23. It is characterized in that the inner transfer cavity 2 further includes an inner tube adapter 24 fixedly connected to one end of the inner tube 21, a pressing block 25, and a handle 26 for fixing the pressing block 25. A replaceable semi-permeable filter paper 27 is provided between the pressing block 25 and the inner tube adapter 24. The semi-permeable filter paper 27 is used for filtering air. The outer transfer cavity 1 and the inner transfer cavity 2 are made of metal.

[0029] The outer transfer cavity 1 includes an outer tube 11, a first outer end cover 12, a second outer end cover 13, and multiple screw rods 14. The first outer end cover 12 and the second outer end cover 13 are respectively located at both ends of the outer tube 11, and the first outer end cover 12 and the second outer end cover 13 are connected and fixed to the outer tube 11 through the multiple screw rods 14.

[0030] The pressing block 25 is provided with a plurality of filter holes 251, and the handle 26 is provided with air holes 261 corresponding to the filter holes 251. The carrier 22 is threadedly connected to the inner tube 21. The carrier 22 includes a connection block 221 fixed to the end of the inner tube 21 and an arc plate 222 extending into the inner tube 21. The connection block 221 is provided with a through hole 221a, and the through hole 221a communicates the outer transfer cavity 1 and the inner transfer cavity 2.

[0031] Please refer to Figure 5 , Figure 6 , both the first outer end cover 12 and the second outer end cover 13 are provided with limit rings 121. The two ends of the outer tube 11 are respectively provided with limit grooves 111 corresponding to the limit rings 121. The limit rings 121 are provided with a first sealing ring a in contact with the limit grooves 111. The second outer end cover 13 is provided with an air inlet nozzle 131, and the inner end cover 23 is provided with an air outlet nozzle 231 corresponding to the air inlet nozzle 131. Both the first outer end cover 12 and the second outer end cover 13 are provided with a holding part 123 for holding.

[0032] Please refer to Figure 7 , the inner tube adapter 24 includes a fixed section 241 fixedly connected to the end of the inner tube 21, a transition section 242 for accommodating part of the air outlet nozzle 231, and a connection section 243 detachably connected to the end of the outer tube 11. The first outer end cover 12 is provided with a circular hole 122 corresponding to the connection section 243. The diameter of the end of the connection section 243 is larger than the aperture of the circular hole 122.

[0033] The connection section 243 is provided with a second sealing ring b in contact with the inner wall of the outer tube 11. The connection section 243 is provided with an annular groove 243a for accommodating the semi-permeable filter paper 27. The handle 26, the pressing block 25, and the connection section 243 are all provided with corresponding screw holes, and the handle 26, the pressing block 25 and the inner tube adapter 24 are connected and fixed by bolts. The inner tube 21 and the inner end cover 23 are connected and fixed by bolts, and there is a third sealing ring c between the inner end cover 23 and the inner tube 21.

[0034] During use, first take out the inner transfer cavity 2. Then place the living creature on the arc plate 222 and send it into the inner tube 21. Next, threadedly connect and fix the support 22 to the inner tube 21. Then install the semi-permeable filter paper 27. Place the semi-permeable filter paper 27 in the annular groove 243a and then place the pressing block 25 and the handle 26 in sequence. Then connect and fix the handle 26 to the inner tube adapter 24 through a bolt. At this time, the handle 26 presses the pressing block 25, and the pressing block 25 presses the semi-permeable filter paper 27, so that the semi-permeable filter paper 27 remains flat and is fixed to the connection section 243. Finally, insert the inner transfer cavity 2 into the outer tube 11, so that the connection section 243 contacts the first outer end cover 12 and the inner wall of the outer tube 11 respectively, and the installation is completed. For the installed small animal aseptic transfer device, the first outer end cover 12, the second outer end cover 13 and the outer tube 11 are sealed by the first sealing ring a, and the inner tube adapter 24 and the outer tube 11 are sealed by the second sealing ring b. The first sealing ring a and the second sealing ring b make the outer transfer cavity 1 have a good sealing effect.

[0035] When taking out the inner transfer cavity 2, just pull the handle 26 and take out the inner transfer cavity 2 away from the second outer end cover 13.

[0036] Therefore, after use, it can be reused only by replacing the semi-permeable filter paper 27 and cleaning the inner tube 21 and the support 22. During the process of continuously disassembling and installing the inner transfer cavity 2 and the outer transfer cavity 1, the second sealing ring b will be worn and the sealing performance will decrease. At this time, just replace the second sealing ring b to reuse the small animal aseptic transfer device.

[0037] During transportation, the pipeline is connected to the air inlet nozzle 131, and air continuously enters the outer tube 11 through the air inlet nozzle 131, then enters the inner tube 21 through the through hole 221a, and then contacts the semi-permeable filter paper 27 through the air outlet nozzle 231. The air is filtered by the semi-permeable filter paper 27 and then discharged.

[0038] The connection section 243 of the inner tube adapter 24 is accommodated in the circular hole 122 of the first outer end cover 12, so that the outer tube 11 and the inner view are axially coincident, preventing the radial movement of the inner tube 21. Through the sealing ring of the connection section 243 contacting the inner wall of the outer tube 11, the axial movement of the inner tube 21 is prevented. The inner transfer cavity 2 and the outer transfer cavity 1 are detachably connected.

[0039] In the second embodiment of the present invention, the handle 26 and the inner tube adapter 24 are threadedly connected and fixed. By pressing the semi-permeable filter paper 27 and the pressing block 25 with the handle 26, the semi-permeable filter paper 27 and the pressing block 25 are fixed in the connection section 243. Compared with the bolt connection in the first embodiment, the connection method in this embodiment is more convenient.

[0040] Please refer to Figure 8, in the third embodiment of the present invention, a guiding ring 112 is provided inside the outer tube 11, and the guiding ring 112 has a guiding surface 112a inclined towards the second outer end cap 13.

[0041] When installing the inner transfer cavity 2, the guiding surface 112a helps the insertion of the inner tube 21, and at the same time, the guiding ring 112 can maintain the stability of the inner tube 21 after installation.

[0042] Please refer to Figure 9 , in the fourth embodiment of the present invention, a limit switch 3 is provided on the first outer end cap 12. The limit switch 3 is hinged to the first outer end cap 12 and is used to control the movement and fixation of the inner tube adapter 24. When the limit switch 3 contacts the end face of the inner tube adapter 24, the inner tube adapter 24 is in a fixed state. When the limit switch 3 is disengaged from the end face of the inner tube adapter 24, the inner tube adapter 24 is in a movable state.

[0043] In the present invention, the first outer end cap 12, the second outer end cap 13 and the outer tube 11 are sealed by a first sealing ring a, and the inner tube adapter 24 and the outer tube 11 are sealed by a second sealing ring b. The first sealing ring a and the second sealing ring b enable the small animal sterile transfer device to have a good sealing effect.

[0044] In the present invention, the outer transfer cavity 1 and the inner transfer cavity 2 are detachably connected, so as to facilitate the disassembly and cleaning of the inner transfer cavity 2.

[0045] In the present invention, through the replaceable semi-permeable filter paper 27, the small animal sterile transfer device has the beneficial effects of simple structure, reusable and cost-saving.

[0046] The above are only the preferred embodiments of the present invention, and do not impose any form of limitation on the present invention. Although the present invention has been disclosed above with the preferred embodiments, it is not intended to limit the present invention. Any person skilled in the art, without departing from the scope of the technical solution of the present invention, can make some changes or modifications to the above-disclosed technical content to be equivalent change equivalent embodiments. However, any simple modification, equivalent change and modification made to the above embodiments based on the technical essence of the present invention without departing from the content of the technical solution of the present invention still fall within the scope of the technical solution of the present invention.

Claims

1. A small animal aseptic transfer device, comprising an outer transfer cavity and an inner transfer cavity located within the outer transfer cavity. The inner transfer cavity includes an inner tube, a carrier for holding a living creature, and an inner end cap, and is characterized in that, The inner transfer cavity further includes an inner tube adapter fixedly connected to one end of the inner tube, a pressing block, and a handle for fixing the pressing block. A replaceable semi-permeable filter paper is provided between the pressing block and the inner tube adapter; The outer transfer cavity includes an outer tube, a first outer end cap, a second outer end cap, and a plurality of screw rods. The first outer end cap and the second outer end cap are respectively located at both ends of the outer tube, and the first outer end cap, the second outer end cap and the outer tube are fixedly connected by a plurality of screw rods; The second outer end cap is provided with an air inlet nozzle, and the inner end cap is provided with an air outlet nozzle corresponding to the air inlet nozzle; The inner tube adapter includes a fixed section fixedly connected to the end of the inner tube, a transition section for accommodating part of the air outlet nozzle, and a connection section detachably connected to the end of the outer tube; The pressing block is provided with a plurality of filter holes, and the handle is provided with ventilation holes corresponding to the filter holes; The support is threadedly connected to the inner tube. The support includes a connection block fixedly connected to the end of the inner tube and an arc-shaped plate extending into the inner tube. The connection block is provided with a through hole.

2. The small animal aseptic transfer device according to claim 1, wherein, Both the first outer end cap and the second outer end cap are provided with limit rings. Limit grooves corresponding to the limit rings are respectively provided at both ends of the outer tube. The limit rings are provided with first sealing rings in contact with the limit grooves.

3. The small animal aseptic transfer device according to claim 1, wherein The connection section is provided with a second sealing ring in contact with the inner wall of the outer tube.

4. The small animal aseptic transfer device according to claim 1, wherein The connection section is provided with an annular groove for accommodating the semi-permeable filter paper.

5. The small animal aseptic transfer device according to claim 1, characterized in that, The inner tube and the inner end cap are fixedly connected by bolts, and a third sealing ring is provided between the inner end cap and the inner tube.

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