A prostate implant guide plate and its manufacturing method

Abstract

The present invention relates to the field of radiotherapy, and discloses a prostate implant guide plate and a manufacturing method thereof. The prostate implant guide plate includes an implant guide plate main body. One surface of the implant guide plate main body is a curved surface. A plurality of implant needle holes penetrating through the implant guide plate main body are arranged on the curved surface. A positioning anal plug is also arranged on the curved surface. The positioning anal plug is located on one side of the implant needle holes. A bed plate adaptation component for fixing to a treatment bed plate is further arranged at the bottom of the implant guide plate main body. In the present invention, the prostate implant guide plate is fixed on the treatment bed plate through the bed plate adaptation component. During the radiotherapy process, it is not necessary for a doctor to fix the prostate implant guide plate by hand-held means, which improves the stability of the prostate guide plate itself, reduces the operation difficulty of the doctor, improves the reset accuracy, inserts the positioning anal plug on the prostate implant guide plate into the rectum of the target patient, and increases the position stability between the prostate implant guide plate and the target patient, thereby ensuring the treatment effect of prostate tumors.

Description

Technical Field

[0001] The present invention relates to the field of radiotherapy, and particularly to a prostate implant guide plate and a manufacturing method thereof. Background Art

[0002] Prostate cancer is one of the common malignant tumors in men, and in recent years, the incidence rate of prostate cancer in China has shown a rapid upward trend. In China, for men over 70 years old, the incidence rate of latent prostate cancer is 25%. Among the radical treatment methods for prostate cancer, brachytherapy has developed rapidly due to its good curative effect, less damage, and fewer complications. Brachytherapy is becoming more and more common.

[0003] In 1983, Holm first proposed that under the lithotomy position of the patient, a rectal ultrasound probe combined with a template was used to guide the percutaneous implantation of seeds along the long axis of the body through the perineum for the treatment of prostate cancer. For decades, this surgical method has been widely used as the standard surgical method for prostate seed implantation. In 2002, Chinese experts introduced CT-guided technology into the field of seed implantation treatment, and the accuracy of seed implantation treatment has been significantly improved. In the same year, Liu Shuming et al. developed an individualized three-dimensional template using 3D printing technology and achieved success in the treatment of head and neck tumors. In 2014, Wang Junjie transmitted the scanned information of the patient's tumor target area to the computer treatment planning system through the imaging digital information system. After being designed by professionals, a digital 3D printing template with a coordinate system and fixed needle tracks was printed, and significant effects were achieved in guiding the seed implantation treatment process. Zhang Hongtao et al. made similar attempts for prostate cancer. After the CT data was processed by three-dimensional reconstruction, preoperative positioning was performed, and intraoperative CT scanning was used to determine the position of the implantation needle to guide the implantation of radioactive seeds. The position of the implanted seeds was consistent with the preoperative plan, making the operation simpler and safer.

[0004] Currently, when performing seed implantation treatment on prostate cancer patients, a standard universal guide plate is used. The conventional universal guide plate only sets implantation needle holes on a standard-sized lower flat plate. Then, the doctor holds the universal guide plate and sticks it to the perineum of the patient, and inserts the radiotherapy needle into the implantation needle holes on the universal guide plate to achieve implantation of the patient, and then perform brachytherapy. In the above traditional seed implantation treatment process, the universal guide plate is only a standard plate and cannot be suitable for all patients, which will increase the diagnostic and treatment pain of the patients. Since the universal guide plate is not customized for each patient and the universal guide plate is used as a fixing device for fixation, during the radiotherapy process, the universal guide plate may shift or the patient himself may shift, resulting in the need for continuous reset operations. Summary of the Invention

[0005] To overcome the deficiencies of the prior art, one of the objectives of the present invention is to provide a prostate implant guide plate, which can solve the problems that the general guide plate without a positioning device in the traditional particle implantation treatment process cannot meet the treatment needs of all patients and requires continuous reset operations.

[0006] Another objective of the present invention is to provide a manufacturing method of a prostate implant guide plate, which can solve the problems that the general guide plate without a positioning device in the traditional particle implantation treatment process cannot meet the treatment needs of all patients and requires continuous reset operations.

[0007] One of the objectives of the present invention is achieved by the following technical solutions:

[0008] A prostate implant guide plate includes an implant guide plate main body. One side surface of the implant guide plate main body is a curved surface. A plurality of implant needle holes penetrating the implant guide plate main body are provided on the curved surface. A positioning anal plug is also provided on the curved surface. The positioning anal plug is located on one side of the implant needle holes. A bed plate adapter assembly for fixing to a diagnostic and treatment bed plate is further provided at the bottom of the implant guide plate main body.

[0009] Further, the shape of the positioning anal plug is cylindrical.

[0010] Further, a plurality of spare needle holes are also provided around the implant needle holes. Coordinate identification information is provided on both the implant needle holes and the spare needle holes.

[0011] Further, the number of the bed plate adapters is two, and the two bed plate adapters are respectively fixed on both sides of the bottom of the implant guide plate main body.

[0012] Further, the other side surface of the implant guide plate main body is a plane, and the outer contour of the curved surface is consistent with the outer contour of the perineum of the target patient.

[0013] Further, a personalized baffle is provided at the top of the implant guide plate main body.

[0014] Another objective of the present invention is achieved by the following technical solutions:

[0015] A manufacturing method of a prostate implant guide plate includes the following steps:

[0016] Prostate positioning: performing prostate positioning imaging scanning on a target patient wearing a preset positioning anal plug to obtain a prostate positioning image;

[0017] Intercepting the perineum plane: extracting the prostate positioning image obtained by performing prostate positioning imaging scanning on the target patient and stored in advance, and intercepting the perineum plane corresponding to the perineum part of the target patient in the prostate positioning image;

[0018] Generate a three-dimensional model of the implant guide plate body, use the perineum plane as the implant needle hole area on the preset three-dimensional model of the implant guide plate body, and generate corresponding implant needle holes on the implant needle hole area according to the implant needle information in the preset diagnosis and treatment plan, so as to obtain the three-dimensional model of the implant guide plate body;

[0019] Model splicing, perform model merging processing on the preset three-dimensional model of the positioning anal plug and the three-dimensional model of the implant guide plate body, so that one end of the three-dimensional model of the positioning anal plug is fixed on the three-dimensional model of the implant guide plate body and the three-dimensional model of the positioning anal plug is located on one side of the implant needle hole;

[0020] Add components, add a pre-stored three-dimensional bedplate adapter component to the bottom of the three-dimensional model of the implant guide plate body after the model splicing process to obtain a three-dimensional model of the prostate implant guide plate;

[0021] Generate a prostate implant guide plate, and generate a prostate implant guide plate according to the three-dimensional model of the prostate implant guide plate.

[0022] Further, between the prostate positioning and the intercepted perineum plane, a preset diagnosis and treatment plan is also included. Determine the prostate diagnosis and treatment position of the target patient according to the prostate positioning image, and formulate implant needle information and planned implant depth information according to the prostate diagnosis and treatment position. The implant needle information includes implant needle position coordinate information and diameter information;

[0023] It also includes printing a report. Determine the actual implant depth information according to the planned implant depth information and the three-dimensional model of the prostate implant guide plate, and print the actual implant depth information into a report and output it to the doctor's terminal.

[0024] Further, the generation of the prostate implant guide plate specifically is: generate an integrated prostate implant guide plate according to the three-dimensional model of the prostate implant guide plate, or use the positioning anal plug in the three-dimensional model of the prostate implant guide plate as the first component three-dimensional model, and use the part of the three-dimensional model of the prostate implant guide plate except the positioning anal plug as the second component three-dimensional model. Generate the first component according to the first component three-dimensional model, generate the second component according to the second component three-dimensional model, and combine the first component and the second component to obtain the prostate implant guide plate.

[0025] Further, the generation of the integrated prostate implant guide plate according to the three-dimensional model of the prostate implant guide plate specifically is: perform smoothing processing on the three-dimensional model of the prostate implant guide plate and add identification information to obtain three-dimensional surface data corresponding to the three-dimensional model of the prostate implant guide plate, output the three-dimensional surface data as a 3D printing standard model file, and input it into a 3D printer for printing to obtain the prostate implant guide plate.

[0026] Compared with the prior art, the beneficial effects of the present invention are as follows: a prostate implantation guide in the present application is fixed on a treatment bed board by a bed board adapter assembly. During radiotherapy, the doctor does not need to fix the prostate implantation guide by hand, which improves the stability of the prostate guide itself, reduces the difficulty of operation for the doctor, improves the resetting accuracy, and inserts the positioning butt plug on the prostate implantation guide into the rectum of the target patient, thereby increasing the position stability between the prostate implantation guide and the target patient. The positioning butt plug can support the prostate in the rectum, thereby reducing the tumor position deviation caused by the movement of the prostate position due to problems such as the target patient's bladder filling during treatment, thereby ensuring the treatment effect of prostate tumors.

[0027] The above description is only an overview of the technical solution of the present invention. In order to more clearly understand the technical means of the present invention and implement it according to the contents of the specification, the following is a detailed description of the preferred embodiments of the present invention in conjunction with the accompanying drawings. The specific implementation of the present invention is given in detail by the following embodiments and their accompanying drawings. BRIEF DESCRIPTION OF THE DRAWINGS

[0028] The drawings described herein are used to provide a further understanding of the present invention and constitute a part of this application. The exemplary embodiments of the present invention and their descriptions are used to explain the present invention and do not constitute an improper limitation of the present invention. In the drawings:

[0029] Figure 1 It is a front structural schematic diagram of a prostate implantation guide plate of the present invention;

[0030] Figure 2 It is a side structural schematic diagram of a prostate implantation guide plate of the present invention;

[0031] Figure 3 The present invention is a schematic flow chart of a method for manufacturing a prostate implantation guide plate.

[0032] In the figure: 1. Insertion guide body; 11. Insertion pinhole; 12. Spare pinhole; 2. Positioning butt plug; 3. Bed board adapter assembly; 4. Personalized baffle. DETAILED DESCRIPTION

[0033] The present invention is further described below in conjunction with the accompanying drawings and specific implementation methods. It should be noted that, under the premise of no conflict, the various embodiments or technical features described below can be arbitrarily combined to form a new embodiment.

[0034] like Figure 1-2As shown in the figure, a prostate implant guide plate in the present application includes an implant guide plate main body 1. One side surface of the implant guide plate main body 1 is a curved surface. A plurality of implant needle holes 11 penetrating through the implant guide plate main body 1 are provided on the curved surface. A positioning anal plug 2 is also provided on the curved surface. The positioning anal plug 2 is located on one side of the implant needle holes 11. A bed plate adapter assembly 3 for fixing to a treatment couch plate is further provided at the bottom of the implant guide plate main body 1. In this embodiment, the shape of the positioning anal plug is cylindrical. The positioning anal plug is a standardized produced anal plug or an anal plug customized according to the target patient, and the material can be a soft colloid.

[0035] Preferably, in this embodiment, a personalized baffle 4 is provided at the top of the implant guide plate main body 1. The other side surface of the implant guide plate main body 1 is a plane. During the operation by the doctor, only the needle containing the radiation source needs to be inserted from one end of the implant needle hole 11 on the plane. The personalized baffle 4 in this embodiment is a standardized produced plate body or a plate body customized according to the target patient. A supporting part for supporting the penis and scrotum of the target patient, or objects such as a urinary catheter that may affect the implant operation, is provided at the top of the personalized baffle to facilitate the implant operation in the perineum area. The number of the bed plate adapters in this embodiment is two, and the two bed plate adapters are respectively fixed on both sides of the bottom of the implant guide plate main body.

[0036] Preferably, a plurality of spare needle holes 12 are further provided around each implant needle hole 11. When there is a deviation between the position of the implant needle hole 11 and the actual treatment position, the doctor can insert the needle containing the radiation source into the perineum of the target patient from the spare needle hole 12. The implant needle holes 11 in the present application are all set according to the implant needle information in the preset treatment plan corresponding to the target patient. If the target area in the patient's body changes greatly, the needle track can be adjusted, and the flexibility is strong. In this embodiment, coordinate identification information is provided on both the above-mentioned spare needle holes 12 and the implant needle holes 11. The coordinate identification is used to distinguish the positions of each needle hole. The entire curved surface is regarded as a plane rectangular coordinate system, and the positions of each spare needle hole 12 and implant needle hole 11 on the curved surface in the plane rectangular coordinate system are used as the coordinate identification information, that is, the coordinate point information.

[0037] The process of performing radiotherapy on a target patient using the prostate implant guide plate is as follows:

[0038] First, fix the bed board adapter assembly 3 to the diagnostic and treatment bed board. Fix the prostate implant guide plate on the diagnostic and treatment bed board through the bed board adapter assembly 3. Insert the positioning anal plug 2 in the prostate implant guide plate into the patient's rectum. At the same time, make the area with implant needle holes 11 and spare needle holes 12 on the implant guide plate body 1 closely fit above the perineum of the target patient. The personalized baffle 4 at the top of the implant guide plate body 1 pushes objects such as the target patient's penis and scrotum, or urinary catheter that may affect the implant operation above the personalized baffle 4 to facilitate the implant operation in the perineum area. Finally, perform implanting on the perineum of the target patient according to the implant information in the preset diagnosis and treatment plan, and perform brachytherapy.

[0039] As Figure 3 shown, the present invention also provides a manufacturing method of a prostate implant guide plate for manufacturing the aforementioned prostate implant guide plate, specifically including the following steps:

[0040] Prostate positioning: Perform prostate positioning image scanning on the target patient wearing a preset positioning anal plug to obtain a prostate positioning image. In this embodiment, the positioning image scanning is performed using a CT device or an MRI device or an ultrasound device for scanning and imaging.

[0041] Intercept the perineum plane: Extract the pre-stored prostate positioning image obtained by performing prostate positioning image scanning on the target patient, and intercept the perineum plane corresponding to the perineum part of the target patient in the prostate positioning image;

[0042] Generate a three-dimensional model of the implant guide plate body: Use the perineum plane as the implant needle hole area on the preset three-dimensional model of the implant guide plate body, and generate corresponding several implant needle holes on the implant needle hole area according to the implant needle information in the preset diagnosis and treatment plan, so as to obtain a three-dimensional model of the implant guide plate body;

[0043] Model splicing: Perform model merging on the preset three-dimensional model of the positioning anal plug and the three-dimensional model of the implant guide plate body, so that one end of the three-dimensional model of the positioning anal plug is fixed on the three-dimensional model of the implant guide plate body and the three-dimensional model of the positioning anal plug is located on one side of the implant needle hole;

[0044] Add components: Add the pre-stored three-dimensional bed board adapter assembly to the bottom of the three-dimensional model of the implant guide plate body after the model splicing process to obtain a three-dimensional model of the prostate implant guide plate;

[0045] Generate a prostate implant guide plate: Generate a prostate implant guide plate according to the three-dimensional model of the prostate implant guide plate.

[0046] Preferably, between the prostate positioning and the interception of the perineum plane, a preset diagnosis and treatment plan is also formulated, the prostate diagnosis and treatment position of the target patient is determined according to the prostate positioning image, and the implantation needle information and the planned implantation depth information are formulated according to the prostate diagnosis and treatment position, and the implantation needle information includes the implantation needle position coordinate information and diameter information. After the prostate implantation guide is generated, a report is also included, the actual implantation depth information is determined according to the planned implantation depth information and the prostate implantation guide model, and the actual implantation depth information is printed into a report and output to the doctor's terminal.

[0047] Preferably, the generation of the prostate implantation guide is specifically: generating an integrated prostate implantation guide according to the prostate implantation guide three-dimensional model, or, taking the positioning butt plug in the prostate implantation guide three-dimensional model as the first component three-dimensional model, taking the part of the prostate implantation guide three-dimensional model other than the positioning butt plug as the second component three-dimensional model, generating a first component according to the first component three-dimensional model, generating a second component according to the second component three-dimensional model, and combining the first component and the second component to obtain the prostate implantation guide.

[0048] Preferably, generating an integrated prostate implantation guide based on the prostate implantation guide three-dimensional model is specifically: smoothing the prostate implantation guide model and adding identification information to obtain three-dimensional surface data corresponding to the prostate implantation guide model, outputting the three-dimensional surface data as a 3D printing standard model file, and inputting it into a 3D printer for printing to obtain a prostate implantation guide.

[0049] A prostate implantation guide in the present application is fixed on the treatment bed board by a bed board adapter component. During the radiotherapy process, the doctor does not need to fix the prostate implantation guide by hand, which improves the stability of the prostate guide itself, reduces the difficulty of the doctor's operation, and improves the resetting accuracy. The positioning anal plug on the prostate implantation guide is inserted into the rectum of the target patient, which increases the position stability between the prostate implantation guide and the target patient. The positioning anal plug can support the prostate in the rectum, reducing the tumor position deviation caused by the movement of the prostate position due to problems such as the target patient's bladder filling during the treatment process, thereby ensuring the treatment effect of prostate tumors. The use of spare pinholes can be adjusted if the tumor grows in the patient's body, or the shape and position of the tumor change due to problems such as bladder filling, to ensure the treatment effect of the tumor. The use of personalized baffles can push the penis and scrotum of the target patient, or objects such as catheters that may affect the implantation operation, above the personalized baffles to facilitate the implantation operation in the perineum, thereby improving the accuracy and efficiency of the entire radiotherapy.

[0050] The above are only the preferred embodiments of the present invention, and do not impose any form of limitation on the present invention; any ordinary technician in the industry can smoothly implement the present invention according to what is shown in the accompanying drawings of the specification and the above; however, any slight changes, modifications and equivalent changes made by those skilled in the art within the scope of the technical solution of the present invention by using the technical content disclosed above are all equivalent embodiments of the present invention; at the same time, any changes, modifications and evolutions made to the above embodiments based on the essential technology of the present invention are still within the protection scope of the technical solution of the present invention.

Claims

1. A prostate implant guide plate, characterized in that: It includes an implant guide plate body. One surface of the implant guide plate body is a curved surface. A number of implant needle holes penetrating the implant guide plate body are provided on the curved surface. A positioning anal plug is also provided on the curved surface. The positioning anal plug is located on one side of the implant needle holes. A bedplate adaptation component for fixing to a diagnostic and treatment bedplate is further provided at the bottom of the implant guide plate body.

2. The prostate implant guide plate according to claim 1, wherein: The positioning anal plug is cylindrical in shape.

3. The prostate implant guide plate according to claim 1, wherein: A number of spare needle holes are also provided around the implant needle holes. Coordinate identification information is provided on both the implant needle holes and the spare needle holes.

4. The prostate implant guide plate according to claim 1, characterized in that: The number of the bedplate adaptation components is two. The two bedplate adaptation components respectively fix both sides of the bottom of the implant guide plate body.

5. The prostate implant guide plate according to claim 1, wherein: The surface of the other side of the implant guide plate body is a flat surface. The outer contour of the curved surface is consistent with the outer contour of the perineum of the target patient.

6. The prostate implant guide plate according to claim 1, characterized in that: A personalized baffle is provided at the top of the implant guide plate body.

7. A manufacturing method of a prostate implant guide plate according to any one of claims 1-6, characterized in that: It includes the following steps: Prostate positioning: performing prostate positioning imaging scanning on a target patient wearing a preset positioning anal plug to obtain a prostate positioning image; intercepting the perineum plane: extracting the prostate positioning image obtained by previously performing prostate positioning imaging scanning on the target patient, and intercepting the perineum plane corresponding to the perineum part of the target patient in the prostate positioning image; generating a three-dimensional model of the implant guide plate body: using the perineum plane as the implant needle hole area on a preset three-dimensional model of the implant guide plate body, and generating a corresponding number of implant needle holes on the implant needle hole area according to the implant needle information in the preset diagnostic and treatment plan, so as to obtain a three-dimensional model of the implant guide plate body; model splicing: performing model merging on the preset three-dimensional model of the positioning anal plug and the three-dimensional model of the implant guide plate body, so that one end of the three-dimensional model of the positioning anal plug is fixed on the three-dimensional model of the implant guide plate body and the three-dimensional model of the positioning anal plug is located on one side of the implant needle holes; adding components: adding a pre-stored three-dimensional bedplate adaptation component to the bottom of the three-dimensional model of the implant guide plate body after the model splicing process to obtain a three-dimensional model of the prostate implant guide plate; generating a prostate implant guide plate: generating a prostate implant guide plate according to the three-dimensional model of the prostate implant guide plate.

8. The manufacturing method of a prostate implant guide plate according to claim 7, characterized in that: Between the prostate positioning and the intercepting of the perineum plane, it also includes formulating a preset diagnostic and treatment plan. Determining the prostate diagnosis and treatment position of the target patient according to the prostate positioning image, formulating implant needle information and planned implant depth information according to the prostate diagnosis and treatment position. The implant needle information includes implant needle position coordinate information and diameter information; it also includes printing a report. Determining the actual implant depth information according to the planned implant depth information and the three-dimensional model of the prostate implant guide plate, and printing the actual implant depth information into a report and outputting it to a doctor's terminal.

9. The manufacturing method of a prostate implant guide plate according to claim 7, characterized in that: The generation of the prostate implant guide plate specifically includes: generating an integrated prostate implant guide plate according to the three-dimensional model of the prostate implant guide plate; or, using the positioning anal plug in the three-dimensional model of the prostate implant guide plate as the three-dimensional model of the first component, using the part of the three-dimensional model of the prostate implant guide plate other than the positioning anal plug as the three-dimensional model of the second component, generating the first component according to the three-dimensional model of the first component, generating the second component according to the three-dimensional model of the second component, and combining the first component and the second component to obtain the prostate implant guide plate.

10. The manufacturing method of a prostate implant guide plate according to claim 9, characterized in that: The generation of the integrated prostate implant guide plate according to the three-dimensional model of the prostate implant guide plate specifically includes: performing smoothing processing on the three-dimensional model of the prostate implant guide plate and adding identification information to obtain three-dimensional surface data corresponding to the three-dimensional model of the prostate implant guide plate, outputting the three-dimensional surface data as a 3D printing standard model file, and inputting it into a 3D printer for printing to obtain the prostate implant guide plate.

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