Foldable scleral cross-linking device and scleral cross-linking equipment

Abstract

The present invention relates to the technical field of ophthalmic medical devices, and in particular to a foldable scleral cross-linking device and a scleral cross-linking equipment. The foldable scleral cross-linking device of the present invention comprises: a foldable device body made of a first flexible material and a foldable light-guiding layer made of a second flexible material, the surface of the device body used for contacting the eye treatment site is constructed as a treatment area; the light-guiding layer is arranged in the device body to irradiate the treatment light through the treatment area to the eye treatment site; a treatment cavity is arranged in the device body, and the treatment cavity is arranged between the light-guiding layer and the treatment area, a treatment hole connected to the treatment cavity is arranged on the treatment area, and the treatment cavity is connected to an injection device so that the treatment solution is dripped into the eye treatment site through the treatment hole. The present invention has the advantages of small incision, accurate positioning, flexible operation, and precise quantification, and can achieve accurate positioning and perform minimally invasive and precise scleral cross-linking operations.

Description

Technical Field

[0001] The present invention relates to the technical field of ophthalmic medical devices, and in particular to a foldable sclera cross-linking device and a sclera cross-linking equipment. Background Art

[0002] UV-riboflavin cross-linking technology is a method that creates covalent bonds within and between collagen molecules to increase the tension and stability of collagen fibers. Current studies have shown that this method can enhance the biomechanical strength of corneal and scleral tissues, and is expected to become a new therapy for preventing and controlling the development of myopia.

[0003] In the prior art, a separate ultraviolet irradiation device and an operator manually dripping riboflavin solution are used to operate the ultraviolet-riboflavin cross-linking technology. The existing cross-linking equipment usually includes four parts: a working device, a control device, a light source device, and a power supply device. Among them, the working device is used to aim at the patient's eye treatment site and irradiate the corresponding treatment light, and the working device is usually a cylindrical probe structure; the control device is used to display and control the working state of the working device; the light source device is used to generate light for irradiation treatment; the power supply device is used to provide power to the working device, the control device, and the perfusion device.

[0004] When the above-mentioned method is used for scleral cross-linking, in order to achieve an effective cross-linking range, the conjunctival sac needs to be cut open on a large scale, the periorbital tissue needs to be separated, and the extraocular muscles need to be pulled to expose the scleral tissue at the cross-linking site. The surgical wound is large, time-consuming, and the patient feels obvious pain during the pulling of the extraocular muscles. Most of them need to be performed under general anesthesia. At the same time, the existing equipment cannot realize real-time monitoring of ultraviolet irradiation intensity during surgery, and thus cannot flexibly adjust the intensity and range of ultraviolet irradiation. In addition, there are certain requirements for the accuracy of the intraoperative dripping method of riboflavin solution. The individual differences of manual dripping of riboflavin perfusion are large, and it is labor-intensive and inefficient. Summary of the invention

[0005] The present invention provides a foldable sclera cross-linking device and a sclera cross-linking equipment, which are used to solve at least one of the above-mentioned technical problems.

[0006] A first aspect of the present invention provides a foldable scleral cross-linking device, comprising: a foldable device body made of a first flexible material and a foldable light-guiding layer made of a second flexible material,

[0007] The device body is used to cover the eye treatment site, and the surface of the device body that is in contact with the eye treatment site is configured as the treatment area.

[0008] The light-guiding layer is disposed in the device body to irradiate the treatment light through the treatment area to the eye treatment site;

[0009] The device body is provided with a treatment cavity, and the treatment cavity is provided between the light-guiding layer and the treatment area, and the treatment area is provided with a treatment hole connected with the treatment cavity.

[0010] The treatment chamber is connected to an irrigation device so that the treatment solution can be dripped into the eye treatment site through the treatment hole.

[0011] In one embodiment, the treatment area is configured as a partial sphere smaller than a hemisphere.

[0012] In one embodiment, the first flexible material is silicone, hydrogel or acrylic; and / or

[0013] The second flexible material is a flexible light-guiding material.

[0014] In one embodiment, the device body includes a main body portion and a pushing portion connected to each other.

[0015] The light-guiding layer and the treatment cavity are arranged in the main body, the treatment area is arranged on the bottom surface of the main body, and the top surface of the pushing portion is provided with scale lines for at least the pushing depth of the main body.

[0016] In one embodiment, the top surface and surrounding edges of the main body are provided with a light-shielding coating.

[0017] In one embodiment, an irradiance monitoring point is provided on the light guiding layer, and the irradiance monitoring point is used to monitor the irradiation intensity of the therapeutic light.

[0018] In one embodiment, the treatment cavity is further connected to an oxygen supply device to deliver oxygen to the eye treatment site through the treatment hole.

[0019] A second aspect of the present invention provides a scleral cross-linking device, comprising: an injection device, a light source device and the above-mentioned foldable scleral cross-linking device,

[0020] Wherein, the irrigation device is connected to the treatment cavity so that the treatment solution is dripped into the eye treatment area through the treatment hole;

[0021] The light source device is used to generate a variety of therapeutic light rays, and the light source device is connected to the light guide layer through a light guide fiber to transmit the therapeutic light rays to the light guide layer.

[0022] In one embodiment, it further comprises:

[0023] An oxygen supply device is connected to the treatment cavity to deliver oxygen to the eye treatment site through the treatment hole.

[0024] In one embodiment, it further comprises:

[0025] A visualization device is used to guide and monitor the exposure of an eye treatment site and to guide the treatment area of ​​the foldable sclera cross-linking device to cover the eye treatment site.

[0026] Compared with the prior art, the advantages of the present invention are:

[0027] The foldable sclera cross-linking device and sclera cross-linking equipment of the present invention have the advantages of small incision, accurate positioning, flexible operation, and precise quantification, and can achieve accurate positioning and perform minimally invasive and precise sclera cross-linking operations.

[0028] The scleral cross-linking device of the present invention is made of a flexible material. During cross-linking treatment, the scleral cross-linking device can be folded and entered from a smaller surgical incision. After reaching the eye treatment area, it is unfolded and covered in the eye treatment area, which can play a role in fixing and supporting the periocular tissue and ensuring the fixation of the treatment position. Therefore, there is no need to cut the conjunctival sac on a large scale to separate the periorbital tissue and pull the extraocular muscles to expose the scleral tissue at the cross-linking site, which can reduce the size of the surgical incision to a certain extent and reduce intraoperative damage, and is conducive to shortening the operation time. At the same time, by providing a light guide layer, a treatment cavity and a treatment hole, the riboflavin solution can be automatically perfused before and during irradiation treatment, reducing manual operations, thereby improving the efficiency and accuracy of cross-linking. BRIEF DESCRIPTION OF THE DRAWINGS

[0029] Hereinafter, the present invention will be described in more detail based on embodiments and with reference to the accompanying drawings.

[0030] Figure 1 is a schematic structural diagram of a scleral cross-linking device according to an embodiment of the present invention;

[0031] Figure 2 is a front view of a scleral cross-linking device according to an embodiment of the present invention;

[0032] Figure 3 It is a schematic diagram of the arrangement positions of irradiance monitoring points on a light guide layer in one embodiment of the present invention;

[0033] Figure 4 is a schematic diagram of the arrangement position of a light-shielding coating in one embodiment of the present invention;

[0034] Figure 5 is a schematic diagram of a scleral cross-linking device in use according to an embodiment of the present invention;

[0035] Figure 6 is a top view of a scleral cross-linking device in use according to an embodiment of the present invention;

[0036] Figure 7is a schematic structural diagram of a perfusion device in one embodiment of the present invention;

[0037] Figure 8 is a schematic structural diagram of an oxygen supply device according to an embodiment of the present invention;

[0038] Fig. 9 It is a schematic diagram of the structure of a control device of an embodiment of the present invention.

[0039] Reference numerals:

[0040] 1-scleral cross-linking device; 2-perfusion device; 3-oxygen supply device; 4-control device;

[0041] 11-main body; 12-pushing part; 13-light guide layer; 14-treatment cavity;

[0042] 15-perfusion catheter; 16-oxygen supply catheter;

[0043] 111-treatment area; 112-treatment hole; 113-light-shielding coating;

[0044] 121- scale line; 131- irradiance monitoring point;

[0045] 21-injector; 22-second display screen;

[0046] 31- oxygen cylinder; 32- oxygen valve; 33- oxygen delivery tube;

[0047] 41-third display screen; 42-operation switch; 43-infusion control knob; 44-power control knob;

[0048] 45- oxygen control knob; 46- control switch; 47- plug interface. DETAILED DESCRIPTION

[0049] The present invention will be further described below in conjunction with the accompanying drawings.

[0050] like Figure 1-6 As shown in , according to the first aspect of the present invention, the foldable scleral cross-linking device 1 of the present invention comprises: a foldable device body made of a first flexible material and a foldable light-guiding layer 13 made of a second flexible material. The device body is used to cover the eye treatment site, and the surface of the device body used to contact the eye treatment site is configured as a treatment area 111; the light-guiding layer 13 is arranged in the device body to irradiate the eye treatment site with therapeutic light through the treatment area 111; a treatment cavity 14 is arranged in the device body, and the treatment cavity 14 is arranged between the light-guiding layer 13 and the treatment area 111, and a treatment hole 112 connected to the treatment cavity 14 is arranged on the treatment area 111, and the treatment cavity 14 is connected to the perfusion device 2, so that the treatment solution is dripped into the eye treatment site through the treatment hole 112.

[0051] Wherein, the above-mentioned eye treatment site is the eye cross-linking treatment site, the treatment solution is riboflavin solution, and the treatment light is ultraviolet light.

[0052] The foldable sclera cross-linking device 1 and the sclera cross-linking equipment of the present invention have the advantages of small incision, accurate positioning, flexible operation, and precise quantification, and can achieve accurate positioning and perform minimally invasive and precise sclera cross-linking operations.

[0053] The device body and the light guide layer 13 of the sclera cross-linking device 1 of the present invention are respectively made of corresponding flexible materials, so that the sclera cross-linking device 1 can be folded, for example, along the Figure 2 Fold as shown in the dashed line.

[0054] During cross-linking treatment, after the sclera cross-linking device 1 is folded, it can enter from a smaller surgical incision, and after reaching the eye treatment area 111, it can be unfolded and cover the eye treatment area 111, which can play a role in fixing and supporting the periocular tissue to assist in exposing the eye treatment area 111, and can ensure the fixation of the treatment position, so there is no need to cut the conjunctival sac on a large scale to separate the periorbital tissue and pull the extraocular muscles to expose the sclera tissue at the cross-linking site, which can reduce the size of the surgical incision to a certain extent and reduce intraoperative damage, and is conducive to reducing the length of the operation. At the same time, by providing the light guide layer 13, the treatment cavity 14 and the treatment hole 112, the riboflavin solution can be automatically dripped during the irradiation treatment, reducing manual operations, thereby improving the efficiency and accuracy of the cross-linking.

[0055] It should be noted that the device body (at least the treatment area 111 thereof) of the sclera cross-linking device 1 is made of a transparent material so that the treatment light emitted by the light-guiding layer 13 can penetrate the treatment area 111 and irradiate the eye treatment site.

[0056] Preferably, the treatment area 111 is set to a partial sphere smaller than a hemisphere to adapt to the shape of the eyeball, thereby facilitating the reduction of the size of the device body so that it can reach the eye treatment site through a small incision.

[0057] Specifically, the first flexible material is silicone, hydrogel or acrylic; and / or the second flexible material is a flexible light-guiding material.

[0058] In other words, the device body is made of a flexible material with good support, such as silicone, hydrogel, acrylic and the like, so that the device body can be folded and inserted into the surgical incision and then unfolded after reaching the eye treatment site. It can also better fix and support the periocular tissue to assist in exposing the eye treatment area 111, which is beneficial to reducing the size of the surgical incision.

[0059] The light guide layer 13 is made of a flexible light guide material, such as a flexible LED light guide material, and is used to irradiate the treatment light to the eye treatment site. The light guide layer 13 made of the flexible light guide material can be folded, for example, along the Figure 3 Fold the dashed line in the .

[0060] In one embodiment, Figure 1-2 As shown in , the device body includes a main body 11 and a pushing part 12 connected to each other. The light guide layer 13 and the treatment cavity 14 are arranged in the main body 11, the treatment area 111 is arranged on the bottom surface of the main body 11, and the top surface of the pushing part 12 is provided with a scale line 121 for at least the pushing depth of the main body 11.

[0061] In other words, in this embodiment, the main body 11 is used to separate the fascia tissue around the eyeball, and plays a role of fixing, supporting and positioning to assist in exposing the eye treatment area. The pushing part 12 is provided to facilitate the pushing of the main body 11, and the operator can use the scale on the top surface to assist in judging whether the main body 11 has reached the eye treatment area 111.

[0062] Specifically, the pushing portion 12 is in an elongated strip shape, and the width of the pushing portion 12 is smaller than the width of the main body 11 .

[0063] In one embodiment, if Figure 4 As shown in FIG, the top surface and the edges of the main body 11 are provided with a light-shielding coating 113. The light-shielding coating 113 is used to block and absorb light irradiated outside the eye treatment site, thereby preventing light leakage during the treatment process, protecting the operator from light radiation, making the treatment process safer and more controllable, and reducing the possibility of injury to the operator.

[0064] In another embodiment, the non-working surface and surrounding edges of the light-guiding layer 13 are provided with a light-shielding coating 113 , thereby also being able to prevent light leakage during the treatment process.

[0065] It should be noted that the side surface of the light guide layer 13 opposite to the treatment area 111 is set as its working surface, and the other side surface is its non-working surface.

[0066] Preferably, an irradiance monitoring point 131 is provided on the light guide layer 13, and the irradiance monitoring point is used to monitor the irradiance intensity of the treatment light. By setting the irradiance monitoring point, fixed-point ultraviolet light irradiance sensing monitoring can be performed on different sites of the eye treatment area, so that the irradiance intensity of the treatment light can be adjusted according to the monitored irradiance intensity data. Furthermore, the monitored irradiance intensity data is fed back to the control device 4 in real time, so that precise quantitative control can be achieved.

[0067] Specifically, a plurality of evenly arranged irradiance monitoring points 131 are provided on the light guide layer 13. Figure 3As shown in the figure, an irradiance monitoring point 131 is arranged at the center of the light guide layer 13 , and four irradiance monitoring points 131 are evenly arranged at the outer peripheral edge of the light guide layer 13 .

[0068] In one embodiment, the treatment cavity 14 is also connected to the oxygen supply device 3 to deliver oxygen to the eye treatment site through the treatment hole 112. The oxygen supply device 3 can deliver oxygen to the cross-linking treatment process in real time, solving the problem of insufficient oxygen content in the relatively closed space of the small incision and improving the feasibility of the cross-linking operation.

[0069] Specifically, Figure 1-2 As shown in FIG, the oxygen supply device 3 is connected to the treatment cavity 14 through an oxygen supply conduit 16. Further, the oxygen supply conduit 16 is arranged on one side of the pushing portion 12 of the device body.

[0070] In addition, the perfusion device 2 is connected to the treatment cavity 14 through the perfusion catheter 15. During the treatment process, the perfusion device 2 delivers the treatment solution (riboflavin solution) to the treatment cavity 14 through the perfusion catheter 15. Further, the perfusion catheter 15 is arranged on one side of the pushing portion 12.

[0071] According to the second aspect of the present invention, the present invention also provides a scleral cross-linking device, comprising: an injection device 2, a light source device, an oxygen supply device 3, a visualization device and the above-mentioned foldable scleral cross-linking device 1.

[0072] The perfusion device 2 is connected to the treatment cavity 14 so that the treatment solution is dripped into the eye treatment area 111 through the treatment hole 112. The light source device is used to generate a variety of treatment lights, and the light source device is connected to the light guide layer 13 through the light guide fiber to transmit the treatment lights to the light guide layer 13. The oxygen supply device 3 is connected to the treatment cavity 14 so that oxygen is delivered to the eye treatment site through the treatment hole 112. The visualization device is used to guide and monitor the exposure of the eye treatment site, and guide the treatment area 111 of the foldable sclera cross-linking device 1 to cover the eye treatment site.

[0073] The light source device is described in detail below.

[0074] The light source device is used to generate a variety of therapeutic light rays, and is connected to the light guide layer 13 via light guide fibers to transmit the therapeutic light rays to the light guide layer 13 .

[0075] The optical fiber is connected to the non-working surface of the optical layer 13. Preferably, the optical fiber passes from the pushing portion 12 into the portion of the main body 11 located above the optical layer 13 to connect to the non-working surface of the optical layer 13, making the wiring simple.

[0076] Specifically, the housing of the light source device is provided with a first display screen for displaying ultraviolet light output parameters and the operating status of the light source device, a power control button for switching and controlling the output power of the light source, and an ultraviolet light output component for outputting therapeutic ultraviolet light. The ultraviolet light output component is connected to the non-working surface of the illumination plate 21 through a light guide fiber.

[0077] The therapeutic light emitted by the light source device includes but is not limited to a wavelength between 350nm and 390nm and a power of 3mW / cm 2 Up to 30mW / cm 2 The light source is an LED lamp. In addition, the light source can also have an illumination function, an indication function or a measurement function.

[0078] The oxygen supply device 3 will be described in detail below.

[0079] The oxygen supply device 3 is connected to the treatment cavity 14 to deliver oxygen to the eye treatment site through the treatment hole 112. The oxygen supply device 3 can deliver oxygen to the cross-linking treatment process in real time, solving the problem of insufficient oxygen content in the relatively closed space of the small incision and improving the feasibility of the cross-linking operation.

[0080] The oxygen supply device 3 is connected to the treatment cavity 14 via an oxygen supply conduit 16 .

[0081] Specifically, Figure 8 As shown in the figure, the oxygen supply device 3 includes: an oxygen cylinder 31 for storing oxygen, an oxygen valve 32 for controlling oxygen delivery is arranged at the outlet of the oxygen cylinder 31, the outlet end of the oxygen valve 32 is connected to an oxygen delivery pipe 33, and the oxygen delivery pipe 33 is connected to the treatment cavity 14 of the scleral cross-linking device 1 through an oxygen supply conduit 16 with a smaller diameter.

[0082] The visualization device is described in detail below.

[0083] The visualization device is used to guide and monitor the exposure of the eye treatment site, and guide the treatment area 111 of the sclera cross-linking device 1 to cover the eye treatment site, thereby ensuring accurate positioning and performing minimally invasive and precise sclera cross-linking operations.

[0084] The visualization device includes: an endoscope probe, a light guide fiber and a display. The endoscope probe is used to capture and collect images of the treatment site; the light guide fiber is used to transmit image signals; and the display is used to display real-time images of the treatment site.

[0085] The visualization device in the present invention may be an independently arranged device, or its endoscope probe may be arranged on the sclera cross-linking device 1 .

[0086] The filling device 2 will be described in detail below.

[0087] like Figure 7 As shown in FIG. 1 , the filling device 2 comprises a syringe 21 and a regulating element.

[0088] The syringe 21 is used to extract the riboflavin solution required for the cross-linking treatment. The syringe 21 is arranged on the outer wall of the shell of the perfusion device 2 , and the syringe 21 is connected to the treatment cavity 14 of the sclera cross-linking device 1 through the perfusion catheter 15 .

[0089] The regulating element is arranged in the housing of the perfusion device 2, and the regulating element is connected to the injection head of the syringe 21 to adjust the injection speed, dosage and frequency of the injection head.

[0090] The housing of the perfusion device 2 is also provided with a second display screen 22 for displaying perfusion parameters and the operating status of the perfusion device 2 , and buttons for setting perfusion parameters and / or controlling the operating status of the perfusion device 2 .

[0091] It should be noted that the sclera cross-linking device of the present invention further includes: a control device 4 and a power supply device.

[0092] The control device 4 is electrically connected to the sclera cross-linking device 1 (irradiance monitoring point 131 on the light guide layer 13), the perfusion device 2, the light source device and the oxygen supply device 3 through wires. The power supply device is electrically connected to the control device 4, the sclera cross-linking device, the perfusion device 2, the light source device and the oxygen supply device 3 to supply power to them.

[0093] Specifically, Fig. 9 As shown in the figure, the housing of the control device 4 is provided with a third display screen 41 for displaying the data parameters and operating status of the device controlled by it, a working operation switch 42 for starting and terminating the scleral cross-linking device 1, a perfusion control button 43 for controlling the perfusion speed of the riboflavin solution, a power control button 44 for controlling the output power of the light source, an oxygen control button 45 for controlling the oxygen delivery rate, and a control switch 46 for starting and terminating the control device 4. At the same time, the housing of the control device 4 is also provided with a plug interface 47 for connecting with the scleral cross-linking device 1, the perfusion device 2, the light source device, the oxygen supply device 3, and the power supply device.

[0094] In addition, the sclera cross-linking device in the present invention can be configured as an integrated device, which is relatively small in size, easy to carry, simple and flexible to operate, and is more suitable for fine ophthalmic surgery than large devices.

[0095] The following specifically describes the method for scleral cross-linking treatment using the scleral cross-linking device of the present invention.

[0096] In the present invention, the method for performing scleral cross-linking using the above-mentioned scleral cross-linking device comprises the following steps:

[0097] Step 1: Under the guidance and monitoring of the visualization device, the conjunctival sac is cut to separate the periorbital tissue and the extraocular muscles are retracted to form a surgical incision to expose the eye treatment area.

[0098] Step 2: After the scleral cross-linking device 1 is folded, it is inserted into the surgical incision and then unfolded. Then, under the guidance and monitoring of the visualization device, the treatment area 111 of the scleral cross-linking device 1 is covered on the eye treatment site.

[0099] Step 3: The treatment solution is input into the treatment cavity 14 (of the sclera cross-linking device 1) for a first preset time through the perfusion device 2 to infiltrate the eye treatment site.

[0100] Step 4: The therapeutic light is irradiated onto the eye treatment site through the treatment area 111 through the light-guiding layer 13 (of the sclera cross-linking device 1), and the therapeutic solution is input into the treatment cavity 14 through the perfusion device 2 to perform cross-linking treatment on the eye treatment site until the second preset time is reached.

[0101] Specifically, in step 1, the operator cuts the periocular tissue under the guidance of the real-time image of the visualization device to accurately expose the eye treatment site, which reduces the surgical incision and helps shorten the operation time.

[0102] In step 2, the real-time image of the visualization device is used to guide the accurate positioning of the sclera cross-linking device 1, thereby making the treatment process more accurate.

[0103] Step 3 is a photosensitizer infiltration step of the eye treatment area 111. Step 4 is a cross-linking treatment step.

[0104] Step 4 also includes: introducing oxygen into the treatment cavity 14 through the oxygen supply device 3. During the cross-linking treatment, the problem of insufficient oxygen content in the relatively closed space of the small incision is solved by delivering oxygen, thereby improving the feasibility of the cross-linking operation.

[0105] The present invention has the advantages of small incision, accurate positioning, flexible operation, and precise quantification. Under the guidance of a visualization device, accurate positioning can be achieved and minimally invasive and precise scleral cross-linking operations can be performed.

[0106] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0107] In the description of the present invention, it is necessary to understand that the orientation or positional relationship indicated by the terms "bottom", "side", etc. is based on the orientation or positional relationship shown in the accompanying drawings. It is only for the convenience of describing the present invention and simplifying the description, and does not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operate in a specific orientation, and therefore cannot be understood as a limitation of the present invention. In addition, the terms "first" and "second" are only used for descriptive purposes, and cannot be understood as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Therefore, the features defined as "first" and "second" may explicitly or implicitly include one or more of the features.

[0108] Although the present invention has been described with reference to preferred embodiments, various modifications may be made thereto and parts thereof may be replaced by equivalents without departing from the scope of the present invention. In particular, the various technical features mentioned in the various embodiments may be combined in any manner as long as there are no structural conflicts. The present invention is not limited to the specific embodiments disclosed herein, but includes all technical solutions falling within the scope of the claims.

Claims

1. A foldable scleral cross-linking device, characterized in that: include: a foldable device body made of a first flexible material and a foldable light-guiding layer made of a second flexible material, Wherein, the device body is used to cover the eye treatment site, and the surface of the device body that is used to contact the eye treatment site is configured as the treatment area; The light-guiding layer is disposed in the device body to irradiate the treatment light through the treatment area to the eye treatment site; The device body is provided with a treatment cavity, and the treatment cavity is provided between the light-guiding layer and the treatment area, and the treatment area is provided with a treatment hole connected with the treatment cavity. The treatment chamber is connected to a perfusion device so that the treatment solution is dripped into the eye treatment site through the treatment hole; The light guiding layer is provided with irradiance monitoring points, and the irradiance monitoring points are used to monitor the irradiation intensity of the therapeutic light.

2. The foldable sclera cross-linking device according to claim 1, characterized in that: The treatment area is configured as a partial sphere smaller than a hemisphere.

3. The foldable sclera cross-linking device according to claim 1 or 2, characterized in that: The first flexible material is silicone, hydrogel or acrylic.

4. The foldable sclera cross-linking device according to claim 1 or 2, characterized in that: The device body comprises a main body part and a pushing part connected to each other, The light-guiding layer and the treatment cavity are arranged in the main body, the treatment area is arranged on the bottom surface of the main body, and the top surface of the pushing portion is provided with scale lines for at least the pushing depth of the main body.

5. The foldable sclera cross-linking device according to claim 4, characterized in that: The top surface and the edges around the main body are all provided with a light-shielding coating.

6. The foldable sclera cross-linking device according to claim 1 or 2, characterized in that: The treatment cavity is also connected to an oxygen supply device to deliver oxygen to the eye treatment site through the treatment hole.

7. A scleral cross-linking device, characterized in that: include: An injection device, a light source device and a foldable sclera cross-linking device as claimed in any one of claims 1 to 6, Wherein, the irrigation device is connected to the treatment cavity so that the treatment solution is dripped into the eye treatment area through the treatment hole; The light source device is used to generate a variety of therapeutic light rays, and the light source device is connected to the light guide layer through a light guide fiber to transmit the therapeutic light rays to the light guide layer.

8. The scleral cross-linking device according to claim 7, characterized in that Also includes: An oxygen supply device is connected to the treatment cavity to deliver oxygen to the eye treatment site through the treatment hole.

9. The sclera cross-linking device according to claim 7 or 8, characterized in that Also includes: A visualization device is used to guide and monitor the exposure of an eye treatment site and to guide the treatment area of ​​the foldable sclera cross-linking device to cover the eye treatment site.

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