Preparation method of benzoylformic acid
By using the reaction of cheap mandelic acid or its ester with ammonium nitrate and copper salt in a protonated polar solvent, the problem of expensive raw materials and three wastes in the preparation of benzoylformic acid in the existing technology is solved, and an efficient and low-cost method is achieved. The preparation method is suitable for large-scale production and environmental protection requirements.
Patent Information
- Application Number
- CN202210374611.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2022-04-11
- Publication Date
- 2022-07-26
- Estimated Expiration
- 2042-04-11
AI Technical Summary
The existing benzoylformic acid preparation method has problems such as high raw material prices, prominent three wastes generated by post-processing, complex operations, and strict reaction conditions, making it difficult to adapt to large-scale production and environmental protection requirements.
Using cheap and easily available mandelic acid or its ester as raw material, in the presence of protonated polar solvent, ammonium nitrate or amine salt formed from nitric acid and organic base is used as oxidant, copper salt is used as catalyst to react, and the reaction conditions are controlled to achieve high efficiency Preparation of benzoylformic acid.
This method achieves high yield of benzoylformic acid (up to more than 90%), low cost, easy operation, reduced production of three wastes, and is a preparation method suitable for large-scale production and environmental protection requirements.