Guidewire ablation electrode, first ablation device, second ablation device and ablation method

Abstract

The application discloses a guide wire ablation electrode, a first ablation device, a second ablation device and an ablation method, and relates to the field of medical instruments.The guide wire ablation electrode comprises a guide wire inner core, a working end, a connector and an insulating layer, and has the functions of guiding, developing and ablation.The first ablation device comprises the guide wire ablation electrode, a first endoscope, an imaging device, a radio frequency ablation instrument and an ablation electrode, a center of an obstruction part is ablated to form a channel by the working end of the guide wire ablation electrode, the working head end of the ablation electrode is guided into the channel, a larger range of ablation is carried out on the obstruction part, and the treatment of patients with serious obstruction is realized.The second ablation device comprises the guide wire ablation electrode, a second endoscope and the radio frequency ablation instrument, the second endoscope can continuously visually observe the ablation effect during the ablation process, the working end of the guide wire ablation electrode can visually and accurately carry out multi-point repeated ablation on the obstruction part, the damage to non-treatment parts is small, and the safety is high.

Description

TECHNICAL FIELD

[0001] The present application relates to the field of medical devices, in particular to a guide wire ablation electrode, a first ablation device, a second ablation device and an ablation method. BACKGROUND

[0002] Ablation is a minimally invasive surgery, which can be divided into chemical ablation and physical ablation; physical ablation is commonly used in clinical, including radiofrequency ablation, microwave ablation, cryoablation, ultrasonic ablation, laser ablation, etc.; radiofrequency ablation is a relatively mature and commonly used ablation method, which is mainly used for the treatment of nodules, blockages, tumors and other diseases of human tissues and organs; radiofrequency ablation treatment is to puncture an ablation electrode to the lesion site, and to make the cell temperature of the lesion site rise through radiofrequency output power, so that the lesion site is denatured, and finally the tissue of the lesion site is necrotic, so as to achieve the purpose of eliminating nodules, dredging blockages and eliminating tumors through normal metabolism and absorption of the human body.

[0003] Radiofrequency ablation treatment requires a radiofrequency ablation system, which includes a radiofrequency ablation instrument and a radiofrequency ablation electrode; the radiofrequency ablation electrode can act on the obstruction site in the human body pipeline to ablate it. Different treatment organs or sites, different lesion sizes and different lesion properties require different radiofrequency ablation electrodes, such as a biliary radiofrequency ablation electrode for treating malignant biliary obstruction.

[0004] The normal diameter of human bile duct is 6-8 mm, and the total length is 4-8 cm; the bile duct obstruction may exist in a small range, may exist in a large range, may be partially blocked, and there may be only a narrow passage in the bile duct, and the bile duct passage may be completely blocked. The existing ablation methods have the following disadvantages: 1. The conventional biliary radiofrequency ablation electrode only has ablation function; such electrode is often large in diameter, and the reason for the large diameter is that there is a guide wire hole in the middle, which needs to be guided by the guide wire to reach the bile duct obstruction site, but it cannot pass through the site with severe obstruction; 2. The front end of the conventional guide wire is a relatively soft plastic head without ablation function, and it is very soft and cannot pass through the site with severe obstruction; 3. The conventional guide wire cannot pass through the site with severe obstruction, so it is impossible to guide the working head end of the conventional biliary radiofrequency ablation electrode to the center of the site with severe obstruction, resulting in that the working head end of the conventional biliary radiofrequency ablation electrode cannot reach the center of the lesion to perform complete ablation, and the treatment opportunity is lost. SUMMARY

[0005] To solve the above technical problems, the present application provides a guide wire ablation electrode, a first ablation device, a second ablation device and an ablation method, which have the functions of guiding, developing and ablation, and realize the treatment of patients with severe obstruction.

[0006] To achieve the above-mentioned purpose, the present application provides the following solutions:

[0007] The application provides a guide wire ablation electrode, which comprises a guide wire inner core, a working end, a connector and an insulation layer, the front end of the guide wire inner core is connected with the working end, the rear end of the guide wire inner core is detachably installed on the connector, and the insulation layer is wrapped outside the guide wire inner core, and the guide wire inner core and the working end are made of metal materials.

[0008] Preferably, the working end is in a spherical or bullet shape.

[0009] Preferably, the working end is welded to the front end of the guide wire inner core, and the rear end of the guide wire inner core is connected with the connector in a plug-in manner.

[0010] Preferably, the cross section of the insulation layer is in a circular ring shape, and the outer diameter of the cross section of the insulation layer is less than 1 mm.

[0011] Preferably, the insulation layer is made of a hydrophilic material, and the guide wire inner core is made of an alloy material.

[0012] Preferably, a plurality of first coating layers and a plurality of second coating layers are arranged on the outer wall of the insulation layer in the length direction, the first coating layers and the second coating layers are arranged at intervals, and the first coating layers and the second coating layers are different in color.

[0013] The application further provides a first ablation device, which comprises the guide wire ablation electrode, a first endoscope, an imaging device, a radio frequency ablation instrument and an ablation electrode, the connector is used for being connected with the radio frequency ablation instrument, the ablation electrode is provided with a guide wire hole, the first endoscope is used for guiding the guide wire ablation electrode to an obstruction site, the guide wire ablation electrode is used for guiding the ablation electrode to the obstruction site, and the imaging device is used for observing the introduction positions of the guide wire ablation electrode and the ablation electrode.

[0014] The application further provides an ablation method based on the first ablation device, which comprises the following steps.

[0015] Step one, the working end of the guide wire ablation electrode is guided to the obstruction site through the guidance of the first endoscope and the observation of the imaging device, the radio frequency ablation instrument is started, the radio frequency ablation instrument transmits radio frequency energy to the guide wire inner core through the connector, the radio frequency energy is transmitted to the working end through the guide wire inner core, a channel is ablated in the center of the obstruction site, then the radio frequency ablation instrument is turned off, and the working end passes through the obstruction site.

[0016] Step two, the connector is removed, and then the ablation electrode is inserted through the guide wire hole of the ablation electrode from the rear end of the guide wire ablation electrode, the working head end of the ablation electrode is guided into the channel under the observation of the image device, the ablation electrode is connected to the radio frequency ablation instrument, the radio frequency ablation instrument is started, and the radio frequency energy is ablated on the obstruction site through the working head end of the ablation electrode.

[0017] The application also provides a second ablation device, comprising the guide wire ablation electrode, a second endoscope and a radio frequency ablation instrument, the connector is used for connecting with the radio frequency ablation instrument, the second endoscope is used for guiding the guide wire ablation electrode to the obstruction site, and the second endoscope can enter the human body pipeline with the obstruction site and extend to the obstruction site.

[0018] The application also provides an ablation method based on the second ablation device, comprising the following steps: guiding the working end of the guide wire ablation electrode to the obstruction site through the guide wire hole on the second endoscope, the head end of the second endoscope can enter the human body pipeline with the obstruction site and extend to the obstruction site, starting the radio frequency ablation instrument, the radio frequency ablation instrument transmits radio frequency energy to the guide wire inner core through the connector, the radio frequency energy is transmitted to the working end through the guide wire inner core, and the working end ablates the obstruction site under the observation of the second endoscope.

[0019] The application has the following technical effects relative to the prior art:

[0020] The guide wire ablation electrode of the present application comprises a guide wire inner core, a working end, a connector and an insulation layer. The first ablation device comprises a guide wire ablation electrode, a first endoscope, an imaging device, a radio frequency ablation instrument and an ablation electrode. In use, a center of the obstruction site is first ablated by the working end of the guide wire ablation electrode to form a channel, and then the working end is passed through the obstruction site. The ablation electrode is inserted from the rear end of the guide wire ablation electrode, and the working head of the ablation electrode is guided into the channel under the observation of the imaging device to ablate the obstruction site in a larger range. The defects of the conventional guide wire, such as the soft head of the front end and the lack of ablation function, the inability to construct a channel for the severely obstructed site and guide the ablation electrode to the center of the severely obstructed site, are overcome, the treatment of the severely obstructed patients is realized, and the treatment opportunities of the severely obstructed patients are increased. The second ablation device comprises a guide wire ablation electrode, a second endoscope and a radio frequency ablation instrument. The second endoscope is used to guide the guide wire ablation electrode to the obstruction site, and the second endoscope can enter the human body pipeline with the obstruction site and extend to the obstruction site. The working end ablates the obstruction site under the observation of the second endoscope, that is, the obstruction site can be precisely and repeatedly ablated under visual observation, and then the severely obstructed patients can be precisely treated. The second ablation device also has the characteristics of small damage to non-treatment sites and high safety. At the same time, the guide wire ablation electrode can guide itself to pass through the human body pipeline with multiple bends, and can be used as a guide wire to guide the ablation electrode. It can be seen that the guide wire ablation electrode in the present application has the functions of guiding, imaging and ablation. BRIEF DESCRIPTION OF DRAWINGS

[0021] In order to more clearly illustrate the technical solutions in the embodiments of the present application or the prior art, the following will briefly introduce the drawings needed in the embodiments. Obviously, the drawings described below are only some embodiments of the present application, and other drawings can also be obtained by those skilled in the art without creative labor.

[0022] Figure 1 The structure schematic diagram of the guide wire ablation electrode provided by the present application is shown in the figure.

[0023] Figure 2 The structure schematic diagram of the guide wire ablation electrode provided by the present application is shown in the figure. Figure 1 The local enlarged view of A in the figure.

[0024] Figure 3 The schematic diagram of the guide wire ablation electrode passing through the obstruction site in the first ablation device provided by the present application is shown in the figure.

[0025] Figure 4 The schematic diagram of the ablation electrode guided to the obstruction site by the guide wire ablation electrode in the first ablation device provided by the present application is shown in the figure.

[0026] Reference signs: 100, guide wire ablation electrode; 101, guide wire inner core; 102, working end; 103, connector; 104, insulation layer; 200, ablation electrode; 201, working head end; 300, obstruction site. DETAILED DESCRIPTION

[0027] The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative work fall within the scope of the present application.

[0028] The purpose of the present application is to provide a guide wire ablation electrode, a first ablation device, a second ablation device and an ablation method, which have the functions of guiding, imaging and ablation, and realize the treatment of patients with severe obstruction.

[0029] In order to make the above-mentioned purposes, features and advantages of the present application more obvious and easy to understand, the present application will be further described in detail below with reference to the drawings and specific embodiments.

[0030] As shown in FIGS. Figure 1 and Figure 2 The present embodiment provides a guide wire ablation electrode 100, which comprises a guide wire inner core 101, a working end 102, a connector 103 and an insulation layer 104. The front end of the guide wire inner core 101 is connected with the working end 102. The rear end of the guide wire inner core 101 is detachably mounted on the connector 103. The guide wire inner core 101 can be electrically conducted after being connected with the connector 103. The insulation layer 104 is wrapped outside the guide wire inner core 101. The guide wire inner core 101 and the working end 102 are both made of metal material. The metal material is clearly developed under the imaging equipment, which is beneficial for doctors to accurately puncture and guide according to the imaging equipment. The insulation layer 104 can play an insulation role during ablation, preventing damage to normal tissues.

[0031] Specifically, the working end 102 is in the shape of a sphere or a bullet head. The working end 102 in the shape of a sphere or a bullet head has small resistance when entering a narrow bile duct and is not easy to break through the bile duct. At the same time, the working end 102 in the shape of a sphere or a bullet head has a large contact area with the obstruction part of the bile duct, and a large single-point ablation range.

[0032] In the present embodiment, the working end 102 is welded to the front end of the guide wire inner core 101.

[0033] In the present embodiment, the rear end of the guide wire inner core 101 is connected with the connector 103 in a plug-in and plug-out manner, so that the guide wire inner core 101 and the connector 103 are convenient to install and detach.

[0034] Specifically, the cross section of the insulation layer 104 is a circular ring, and the outer diameter of the cross section of the insulation layer 104 is less than 1 mm. That is, the guide wire inner core 101 is wrapped with the insulation layer 104 to form a cylindrical shape, and the diameter of the main body of the guide wire ablation electrode 100 in the embodiment is less than 1 mm. The guide wire ablation electrode 100 in the embodiment is in the form of a thin wire, which can not only pass through the narrow part of the biliary tract obstruction, but also release energy through the working end 102 to ablate the completely blocked part.

[0035] Specifically, the insulation layer 104 is made of a hydrophilic material, and the guide wire inner core 101 is made of an alloy material, specifically, an alloy material with high strength and good toughness, that is, the guide wire ablation electrode 100 itself has a guiding function, which is conducive to the guide wire ablation electrode 100 to pass through the biliary tract along the distribution of the biliary tract.

[0036] In the specific embodiment, the insulation layer 104 is made of Teflon material, and the guide wire inner core 101 is made of nickel-titanium alloy material.

[0037] Specifically, the outer wall of the insulation layer 104 is provided with a plurality of first coatings and a plurality of second coatings along the length direction, the first coatings and the second coatings are arranged at intervals, and the first coatings and the second coatings are different in color. In the specific embodiment, the first coating is black, and the second coating is yellow. Since the insulation layer 104 is made of a hydrophilic material, the doctor may not be able to advance the guide wire ablation electrode 100 when puncturing due to the slippery reason. By using the first coating and the second coating which are different in color and arranged at intervals, the doctor can directly observe the advancement of the guide wire ablation electrode 100, and then adjust in time during operation.

[0038] The embodiment also provides a first ablation device, which comprises the guide wire ablation electrode 100, a first endoscope, an imaging device, a radio frequency ablation instrument and an ablation electrode 200. The connector 103 is used to connect with the radio frequency ablation instrument, the ablation electrode 200 is provided with a guide wire hole, the first endoscope is used to guide the guide wire ablation electrode 100 to the obstruction site 300, the guide wire ablation electrode 100 is used to guide the ablation electrode 200 to the obstruction site 300, and the imaging device is used to observe the introduction position of the guide wire ablation electrode 100 and the ablation electrode 200. The imaging device in the embodiment is an X-ray machine. The first endoscope in the embodiment is a conventional endoscope, and the outer diameter of the first endoscope is larger than the human body pipeline with the obstruction site. Therefore, the first endoscope cannot enter the human body pipeline with the obstruction site during use. The ablation electrode 200 in the embodiment is a conventional ablation electrode, and the conventional ablation electrode can work with the conventional endoscope. The diameter of the conventional ablation electrode is relatively large due to the guide wire hole, so the conventional ablation electrode works with the conventional endoscope, the X-ray machine and the guide wire ablation electrode 100 in the embodiment. The first endoscope in the embodiment is a conventional biliary tract endoscope, and the ablation electrode 200 in the embodiment is a conventional biliary tract radio frequency ablation electrode.

[0039] This embodiment also provides an ablation method based on a first ablation device, including the following steps:

[0040] Step 1, such as Figure 3 As shown, guided by the first endoscope and with the assistance of imaging equipment, the working end 102 of the guidewire ablation electrode 100 is guided to the obstruction site 300. The radiofrequency ablation device is then turned on, and the device transmits radiofrequency energy to the guidewire core 101 through the connector 103. The radiofrequency energy is then transmitted to the working end 102 through the guidewire core 101, ablating a channel in the center of the obstruction site 300. Afterward, the radiofrequency ablation device is turned off, and the working end 102 passes through the obstruction site 300. Specifically, the connector 103 of the guidewire ablation electrode 100 is connected to the radiofrequency ablation device, and the guidewire ablation electrode 100 is inserted into the first endoscope. The doctor can judge the advancement of the guidewire ablation electrode 100 by observing the color of the insulating layer 104 and determine the specific position of the working end 102 of the guidewire ablation electrode 100 through imaging equipment.

[0041] Step Two, as follows Figure 4 As shown, connector 103 is removed, and then the ablation electrode 200 is inserted through the guide wire hole of the ablation electrode 200 from the rear end of the guide wire ablation electrode 100. With the aid of imaging equipment, the working tip 201 of the ablation electrode 200 is guided into the channel. The ablation electrode 200 is then connected to the radiofrequency ablation device, and the device is turned on. Radiofrequency energy is used to ablate the obstruction site 300 through the working tip 201 of the ablation electrode 200. Specifically, utilizing the guiding and imaging functions of the guide wire ablation electrode 100, the position of the working tip 201 of the ablation electrode 200 is determined by the imaging equipment during insertion, ensuring it reaches the center of the channel, allowing for a larger area of ​​ablation in severely obstructed areas. The size of the ablation area is determined by the imaging equipment, thus achieving treatment for patients with severe obstruction.

[0042] This embodiment also provides a second ablation device, including a guidewire ablation electrode 100, a second endoscope, and a radiofrequency ablation instrument. A connector 103 is used to connect to the radiofrequency ablation instrument. The second endoscope is used to guide the guidewire ablation electrode 100 to the obstruction site, and the second endoscope can enter the human body passage with the obstruction site 300 and extend to the obstruction site 300, that is, the ablation process of the obstruction site 300 can be observed through the second endoscope. Specifically, the outer diameter of the second endoscope is smaller than that of the human body passage with the obstruction site, so that the second endoscope can enter the human body passage with the obstruction site.

[0043] The embodiment also provides an ablation method based on the second ablation device, comprising the following steps: guiding the working end 102 of the guide wire ablation electrode 100 to the obstruction site 300 through a guide wire hole on a second endoscope, the head end of the second endoscope can enter the human body pipeline with the obstruction site 300 and extend to the obstruction site 300, turning on a radio frequency ablation instrument, the radio frequency ablation instrument transmits radio frequency energy to the guide wire inner core 101 through the connector 103, the radio frequency energy is further transmitted to the working end 102 through the guide wire inner core 101, and the working end 102 ablates the obstruction site 300 under the observation of the second endoscope, that is, the obstruction site 300 can be precisely and repeatedly ablated in multiple points under visual observation. Specifically, the ablation under the observation of the X-ray machine is indirect observation, and is observed at multiple time nodes before, during and after ablation, that is, intermittent observation is adopted, the ablation under the visual observation of the head end of the second endoscope is direct visual observation, the observation field is clearer, and the ablation effect can be continuously observed during the ablation process, so that the working end 102 can be precisely and repeatedly ablated in multiple points more accurately. The obstruction site 300 can be effectively dredged through precise and repeated ablation in multiple points, so that the patient with severe obstruction can be precisely treated, and the non-treatment site has small damage and high safety.

[0044] Specifically, the diameter of the second endoscope is 2.4-3.8 mm, and the diameter of the guide wire hole is 1.2 mm. The second endoscope in the embodiment is a new type of biliary endoscope.

[0045] It can be seen that the first ablation device in the embodiment overcomes the defects that the front end of the conventional guide wire is a soft head and has no ablation function, and cannot construct a channel to the severe obstruction site and guide the ablation electrode 200 to the center of the severe obstruction site, realizes the treatment of the patient with severe obstruction, and increases the treatment opportunity of the patient with severe obstruction. The second ablation device in the embodiment can guide the working end 102 of the guide wire ablation electrode 100 to the obstruction site 300, and then precisely and repeatedly ablate the obstruction site 300 in multiple points under visual observation, so that the patient with severe obstruction can be precisely treated, and the non-treatment site has small damage and high safety. Meanwhile, the guide wire ablation electrode 100 can guide itself to pass through the human body pipeline with multiple curves on one hand, and can be used as a guide wire to guide the ablation electrode 200 on the other hand. It can be seen that the guide wire ablation electrode 100 in the embodiment has the functions of guiding, developing and ablation.

[0046] The principles and implementation manners of the present application are described in the specification by using specific examples, and the above examples are only used to help understand the method of the present application and its core idea; meanwhile, for those skilled in the art, according to the idea of the present application, the specific implementation manners and application ranges will be changed. In conclusion, the content of the specification should not be understood as a limitation of the present application.

Claims

1. An ablation device, characterized by, The application relates to a guide wire ablation electrode, a first endoscope, an imaging device, a radio frequency ablation instrument and an ablation electrode, wherein the guide wire ablation electrode comprises a guide wire inner core, a working end, a connector and an insulation layer; the front end of the guide wire inner core is connected with the working end; the working end is in the shape of a bullet head; the rear end of the guide wire inner core is detachably mounted on the connector; the rear end of the guide wire inner core is connected with the connector in a plug-in mode; the insulation layer is wrapped on the outside of the guide wire inner core; the guide wire inner core and the working end are made of metal materials; the connector is used for being connected with the radio frequency ablation instrument; the ablation electrode is provided with a guide wire hole; the first endoscope is used for guiding the guide wire ablation electrode to an obstruction part; the guide wire ablation electrode is used for guiding the ablation electrode to the obstruction part; the imaging device is used for observing the guide-in positions of the guide wire ablation electrode and the ablation electrode; the first endoscope is a biliary endoscope; the ablation electrode is a biliary radio frequency ablation electrode; for a serious obstruction part of a biliary tract, the guide wire ablation electrode is used for ablation of a center of the serious obstruction part of the biliary tract to form a channel; then the guide wire ablation electrode is used for guiding the working head end of the biliary radio frequency ablation electrode into the channel ablated by the guide wire ablation electrode to perform expansion ablation.

2. The ablation device of claim 1, wherein, The working end of the guide wire ablation electrode is welded on the front end of the guide wire inner core.

3. The ablation device of claim 1, wherein, The cross section of the insulation layer of the guide wire ablation electrode is in the shape of a circular ring; the outer diameter of the cross section of the insulation layer of the guide wire ablation electrode is less than 1 mm.

4. The ablation device of claim 1, wherein, The insulation layer of the guide wire ablation electrode is made of a hydrophilic material; the guide wire inner core of the guide wire ablation electrode is made of an alloy material.

5. The ablation device of claim 1, wherein, A plurality of first coating layers and a plurality of second coating layers are arranged on the outer wall of the insulation layer of the guide wire ablation electrode along the length direction; the first coating layers and the second coating layers are arranged at intervals; the first coating layers and the second coating layers are different in color.

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