A method for determining the antibacterial activity of sesame compounds from camphor trees and its application
By measuring the antibacterial activity of sesamin-like components in camphor, it was found that 9-hydroxysesamin and sesamin had significant inhibitory effects on the fungus Gliocladium fusca. This solved the problem of insufficient research on the antibacterial activity of sesamin-like components in camphor, revealed its antibacterial mechanism, and provided a basis for the study of the antibacterial activity of camphor.
Patent Information
- Application Number
- CN202210416780.2
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2022-04-20
- Publication Date
- 2025-10-10
- Estimated Expiration
- 2042-04-20
AI Technical Summary
In the prior art, there is little research on the antibacterial activity of sesamin-like components in Cinnamomum camphora, and there is a lack of effective methods for determining the antibacterial activity.
The antibacterial activity of 9-hydroxysesamin and sesamin was determined by mycelial growth rate inhibition method and other methods, including the determination of virulence to pathogens, cell membrane malondialdehyde content, relative conductivity, reducing sugar content and protective enzyme activity, providing a basis for the study of the antibacterial activity of Cinnamomum camphora.
It was found that 9-hydroxysesamin and sesamin have good inhibitory activity against the pathogen Gliocladium schrenkiana, with inhibition rates of 65.53% and 62.67% respectively. They can destroy the cell membrane of the pathogen, regulate enzyme activity and reduce toxic effects, providing a basic basis for the antibacterial activity of Cinnamomum camphora.