A disinfecting and moisturizing dual-effect temperature-controlled foam agent and preparation method thereof
By using specific oil-phase components and low-temperature emulsification technology in ethanol disinfectants, a high-content emulsion and foaming agent are formed, which solves the problem of skin dryness and difficulty in production of ethanol disinfectants, and achieves temperature control and moisturizing the skin. Dual effect.
Patent Information
- Application Number
- CN202110335686.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2021-03-29
- Publication Date
- 2024-12-13
- Estimated Expiration
- 2041-03-29
AI Technical Summary
Existing ethanol disinfectants are prone to dryness and cracking of the skin after use, and high content of ethanol is difficult to form an emulsification system stably, increasing production difficulty and cost.
50-80 wt% ethanol, 2-10 wt% oil-phase components (including combination of cetyl alcohol and octadecanol), 0.5-5 wt% foaming and emulsifying components, 0.1-20 wt% alcohol solvent and 5-40 wt. % purified water is used to form an emulsion with high content of ethanol by low temperature emulsion, and fill it into a propellant to prepare a foam agent to achieve temperature control effect.
It provides a foaming agent that has both disinfection effects and moisturizing the skin, reducing the drying problems caused by ethanol volatility, and simplifies the production process, reduces the cost and difficulty, and realizes the sensitive response of the foam to temperature.
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Abstract
Description
Technical Field
[0001] The invention relates to the field of preparations, and in particular to a disinfecting and moisturizing dual-effect temperature-controlled foam agent and a preparation method thereof. Background Art
[0002] Ethanol disinfectant is currently a widely used disinfectant in the fields of medicine and health. Ethanol is a good skin disinfectant and a fat solvent that can remove grease from the skin. It can also mechanically remove bacteria. It has good volatility and can dry the skin quickly.
[0003] Most of the ethanol disinfectants available on the market are made into gels and sprays, which are convenient to use. However, the disadvantage is that since ethanol can remove grease and evaporates quickly, it can easily cause dry skin and lead to problems such as cracked hands and skin.
[0004] Therefore, there is an urgent need for a disinfectant emollient that has both a disinfecting effect and can replenish oil and moisturize the skin. Emulsion is the best product for replenishing oil and moisturizing the skin. Emulsion can form a film on the surface of hands and skin, which is composed of water and oil and can moisturize hands and skin. However, ethanol is a fat solvent. In almost all emulsion products with ethanol added, ethanol is only used as a solvent in small amounts. Excessive use affects its stability, causing its emulsification system to be destroyed and unable to form a qualified product. At the same time, the formation process of the emulsion is mostly based on high-temperature emulsification, and ethanol will evaporate quickly under high temperature. If you want to prevent ethanol from volatilizing, you need to modify the equipment or cover the surface with liquid nitrogen. These methods will greatly increase the cost and development difficulty of the product.
[0005] Therefore, the art needs to provide a foam disinfectant containing ethanol as a disinfectant component, having a skin-moistening effect, and foam temperature control. Summary of the invention
[0006] The object of the present invention is to provide a foam disinfectant which contains ethanol as a disinfectant component, has a skin-emollient effect and foam temperature control.
[0007] In a first aspect of the present invention, there is provided an emulsion, wherein, by total weight, the emulsion comprises:
[0008] Ethanol 50-80 parts by weight;
[0009] 2-10 parts by weight of oil phase components;
[0010] 0.5-5 parts by weight of foaming and emulsifying ingredients;
[0011] 0.1-20 parts by weight of alcohol solvent; and
[0012] Purified water 5-40 parts by weight;
[0013] Wherein, in the emulsion, the final content of ethanol is ≥50wt%; and
[0014] The oil phase component is a combination of hexadecanol and stearyl alcohol.
[0015] In another preferred embodiment, in the emulsion, the ethanol content is ≥60wt% or ≥70wt%, preferably 65-80wt%, such as 70wt%, 72wt% or 75wt%, based on the total weight of the emulsion.
[0016] In another preferred embodiment, in the emulsion, the content of the oil phase component is 1-5wt%, preferably, 2-4wt%, such as 2.5wt%, 3wt% or 3.5wt%, based on the total weight of the emulsion.
[0017] In another preferred embodiment, in the emulsion, the content of the foaming and emulsifying components is 0.5-3wt%, preferably 1-2wt%, such as 1.2wt%, 1.4wt% or 1.6wt%, based on the total weight of the emulsion.
[0018] In another preferred embodiment, in the emulsion, the content of the alcohol solvent is 0.5-3wt%, preferably 1-2wt%, such as 1.2wt%, 1.4wt%, 1.6wt% or 1.8wt%, based on the total weight of the emulsion.
[0019] In another preferred embodiment, in the emulsion, the content of the purified water is 20-30wt%, preferably 22-26wt%, such as 24wt%, 25wt% or 28wt%, based on the total weight of the emulsion.
[0020] In another preferred embodiment, the oil phase component further comprises one or more substances selected from the following group: dodecanol, tetradecanol, cetostearyl alcohol, behenyl alcohol, or a combination thereof.
[0021] In another preferred embodiment, in the oil phase, the weight ratio of hexadecanol to stearyl alcohol is 1:0.2-2, preferably, 1:0.3-1, more preferably 1:0.4-0.8, such as 1:0.5, 1:0.6 or 1:0.7.
[0022] In another preferred embodiment, in the oil phase, the sum of hexadecanol and stearyl alcohol accounts for 60-100wt% of the total weight of the oil phase, preferably 70-80wt%, such as 65wt%, 75wt%, 85wt%, 90wt% or 95wt%.
[0023] In another preferred embodiment, in the oil phase, the weight ratio of the sum of the hexadecanol and the stearyl alcohol to the hexadecanol is 1:0.1-1, preferably, 1:0.1-0.8, and more preferably 1:0.2-0.5.
[0024] In another preferred embodiment, in the oil phase, the weight ratio of the sum of the hexadecanol and the stearyl alcohol to the behenyl alcohol is 1:0.2-1.5, preferably 1:0.2-1, and more preferably 1:0.4-0.8.
[0025] In another preferred embodiment, in the oil phase, the weight ratio of the sum of the hexadecanol and the stearyl alcohol to the dodecanol is 1:0.1-0.6, more preferably 1:0.2-0.5.
[0026] In another preferred embodiment, the foaming and emulsifying component is a nonionic surfactant. Preferably, the nonionic surfactant is selected from the following group: fatty alcohol polyoxyethylene ether, polyoxyethylene lauryl ether, polyoxyethylene sorbitan, or a combination thereof.
[0027] In another preferred embodiment, the alcohol solvent is a polyol, preferably a short-chain polyol (2-, 3- or 4-hydric alcohol) having 1-6 C atoms, more preferably, the polyol is selected from the following group: pentaerythritol, ethylene glycol, propylene glycol, glycerol, PEG200, PEG300, or a combination thereof.
[0028] In another preferred embodiment, in the emulsion, ethanol accounts for 65-80 parts by weight; preferably 65-75 parts by weight.
[0029] In another preferred embodiment, in the emulsion, the oil phase component is 2-8 parts by weight; preferably 3-7 parts by weight, and more preferably 3-5 parts by weight.
[0030] In another preferred embodiment, in the emulsion, the foaming and emulsifying components are 1-5 parts by weight; preferably 1-3 parts by weight.
[0031] In another preferred embodiment, in the emulsion, the alcohol solvent is 0.5-10 parts by weight; preferably 2-8 parts by weight, and more preferably 3-6 parts by weight.
[0032] In another preferred embodiment, in the emulsion, the purified water is 10-35 parts by weight; preferably 15-30 parts by weight, and more preferably 20-35 parts by weight.
[0033] In another preferred embodiment, the purity of the hexadecanol is ≥98%, preferably 99%, such as 99.5%, or the hexadecanol is pharmaceutical grade hexadecanol.
[0034] In another preferred embodiment, the purity of the octadecanol is ≥98%, preferably 99%, such as 99.5%, or the octadecanol is pharmaceutical grade octadecanol.
[0035] The second aspect of the present invention provides a foaming agent, which is obtained by filling the emulsion according to the first aspect of the present invention and adding a propellant.
[0036] In another preferred embodiment, the amount of the propellant is 5-20 g emulsion / g, preferably, 10-15 g emulsion / g.
[0037] In another preferred embodiment, the propellant is selected from the group consisting of trichloromonofluoromethane, difluoromethane, trichlorotetrafluoroethane, propane, butane, isobutane, or a combination thereof.
[0038] The third aspect of the present invention provides a method for preparing the emulsion according to the first aspect of the present invention, wherein the method comprises the following steps:
[0039] (1) mixing the oil phase component, the foaming and emulsifying component, and the alcohol solvent to form an initial oil phase;
[0040] (2) adding ethanol to the initial oil phase and mixing evenly to form a mixed oil phase;
[0041] (3) Purified water is added to the mixed oil phase for emulsification to form a uniform emulsion.
[0042] In another preferred embodiment, in step (1), the mixing temperature is 70-80°C.
[0043] In another preferred embodiment, in step (2), the mixing temperature is room temperature.
[0044] In another preferred embodiment, in step (2), the emulsification temperature is room temperature, preferably 35-40°C.
[0045] The fourth aspect of the present invention provides a method for preparing the foaming agent as described in the third aspect of the present invention, wherein the method comprises the steps of providing the emulsion as described in the first aspect of the present invention, filling and charging the propellant to obtain the foaming agent.
[0046] The fifth aspect of the present invention provides a use of the emulsion as described in the first aspect of the present invention or the foam as described in the second aspect of the present invention for preparing a disinfectant for disinfecting and / or moisturizing the skin.
[0047] In another preferred embodiment, the disinfectant is in the form of a foam or an emulsion.
[0048] In another preferred embodiment, the disinfection refers to killing pathogens such as bacteria and viruses.
[0049] In another preferred embodiment, the disinfection is skin disinfection.
[0050] It should be understood that within the scope of the present invention, the above-mentioned technical features of the present invention and the technical features specifically described below (such as embodiments) can be combined with each other to form a new or preferred technical solution. Due to space limitations, they will not be described one by one here. DETAILED DESCRIPTION
[0051] The inventors have conducted extensive and in-depth research, and through a large number of screenings and tests, have provided a disinfecting and moisturizing dual-effect temperature-controlled foaming agent. The present invention adopts a specific oil phase composition, solves the problem that the emulsified system is difficult to form and easy to be destroyed due to the large amount of ethanol added to the emulsion, and thus provides an emulsion containing a high content (60-80wt%) of ethanol and a foaming agent prepared therefrom. On the other hand, the emulsion of the present invention can be formed by low-temperature emulsification, solves the problem of large-scale volatilization of ethanol, and greatly reduces the cost of the product and the difficulty of large-scale production.
[0052] At the same time, during the development process, it was surprisingly discovered that as the concentration of ethanol increased, the foam showed a temperature control effect, that is, the foam was sensitive to temperature, and at the right temperature, the foam would melt quickly on its own. Through debugging, the final product can be stable at room temperature below 30°C, and will melt into a colorless liquid on its own at body surface temperature. After disinfection, a protective film composed of water and oil will form on the surface of the hands and skin, which can moisturize the hands and skin and eliminate the dryness and cracking caused by the evaporation of ethanol.
[0053] The present invention has been completed on this basis.
[0054] the term
[0055] Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs.
[0056] As used herein, when used in reference to a specific recited numerical value, the term "about" means that the value may vary by no more than 1% from the recited value. For example, as used herein, the expression "about 100" includes all values between 99 and 101 (e.g., 99.1, 99.2, 99.3, 99.4, etc.).
[0057] As used herein, the term "comprising" or "including (comprising)" may be open, semi-closed and closed. In other words, the term also includes "consisting essentially of" or "consisting of".
[0058] As used herein, the terms "room temperature" or "normal temperature" refer to a temperature of 4-40°C, preferably, 25±5°C.
[0059] As used herein, the term "temperature control" means that the foam melts very slowly (melting time > 300s) on the surface of an object below 30°C, and melts into liquid relatively quickly (melting time is 20-60s per cubic centimeter at 35°C) at temperatures above 30°C (such as body surface temperature of 35°C).
[0060] As used herein, a foaming agent refers to a foaming agent stored in a sealed pressurized container, and when used, the content is sprayed out in the form of foam by pressing a valve.
[0061] Lotion
[0062] The present invention provides an emulsion mixture of an alcohol disinfectant for use in a pressurized can to form a foam dosage form.
[0063] Specifically, based on the total weight of the emulsion, the emulsion includes: 50-80 parts by weight of ethanol; 2-10 parts by weight of oil phase components; 0.5-5 parts by weight of foaming and emulsifying components; 0.1-20 parts by weight of alcohol solvents; and 5-40 parts by weight of purified water; wherein the final content of ethanol in the emulsion is ≥50wt%; and the oil phase component is a combination of hexadecanol and octadecyl alcohol.
[0064] Preferably, based on the total weight of the emulsion, the emulsion comprises: 50-80wt% ethanol; 2-10wt% oil phase component; 0.5-5wt% foaming and emulsifying component; 0.1-20wt% alcohol solvent; and 5-40wt% purified water; wherein, in the emulsion, the final content of ethanol is ≥50wt%; and the oil phase component is a combination of hexadecanol and octadecyl alcohol.
[0065] Preferably, in the emulsion, the final content of ethanol is ≥60wt% or ≥70wt%, preferably 65-80wt%, such as 70wt%, 72wt% or 75wt%, based on the total weight of the emulsion.
[0066] Furthermore, the obtained emulsion is canned and filled with a propellant to obtain the foaming agent of the present invention.
[0067] Emulsion preparation method
[0068] In the present invention, there is no particular limitation on the preparation method of the emulsion, and the emulsion preparation method commonly used in the art can be adopted.
[0069] Typically, the method steps may include:
[0070] (1) mixing the oil phase component, the foaming and emulsifying component, and the alcohol solvent to form an initial oil phase;
[0071] (2) adding ethanol to the initial oil phase and mixing evenly to form a mixed oil phase;
[0072] (3) Purified water is added to the mixed oil phase for emulsification to form a uniform emulsion.
[0073] More specifically, the method for preparing the emulsion of the present invention comprises the steps of:
[0074] (1) mixing the oil phase components, the foaming and emulsifying components, and the alcohol solvent, melting at 70-80° C., and stirring evenly to form an initial oil phase;
[0075] (2) adding ethanol to the initial oil phase at room temperature and mixing evenly to form a mixed oil phase;
[0076] (3) Maintaining the mixed oil phase at about 40°C ± 5, add purified water at room temperature directly into the mixed oil phase to emulsify and form a uniform emulsion.
[0077] The preparation method of the emulsion of the present invention has mild reaction conditions, the required equipment is simple and easy to obtain, and the temperature required in the emulsification process is relatively low (normal temperature), which greatly reduces the danger of using ethanol, solves the problem of ethanol volatilization during the reaction process, and can be used for large-scale production.
[0078] Foaming Agent
[0079] The present invention also provides a foaming agent, which is obtained by filling the emulsion and adding a propellant.
[0080] The product is in the state of emulsion before filling, and foam is sprayed out after filling and adding the propellant. The foam formed by the foaming agent has a temperature control effect, feels light, is easy to apply, feels comfortable on the skin, and is not dry.
[0081] application
[0082] The emulsion or foam of the present invention contains high concentration of alcohol, and thus can realize various uses of alcohol disinfectants, especially for killing pathogens such as various bacteria and viruses.
[0083] In addition, the emulsion or foam of the present invention also has the effect of moisturizing the skin and is very suitable for (but not limited to) skin disinfection.
[0084] The main advantages of the present invention include:
[0085] (1) The present invention provides a foaming agent with a high ethanol content. The foaming agent has a foamy appearance and has a temperature control property, that is, when the temperature on the body surface is 30°C or above, the foam quickly and evenly breaks and melts into a colorless transparent liquid. The foaming agent has all the advantages of a foaming agent, is easy to apply, and has a better feel in use, and is easy to be accepted and liked.
[0086] (2) The foam of the present invention can play a disinfecting role and has various advantages of ethanol disinfectants. At the same time, it can moisturize the skin, making up for the disadvantage of traditional ethanol disinfectants that easily cause dry skin, replenishing the oil dissolved by ethanol, moisturizing the skin, and playing a skin care role.
[0087] The present invention will be further described below in conjunction with specific implementation. It should be understood that these embodiments are only used to illustrate the present invention and are not intended to limit the scope of the present invention. The experimental methods in the following examples without specifying specific conditions are usually based on conventional conditions or the conditions recommended by the manufacturer. Unless otherwise stated, percentages and parts are calculated by weight.
[0088] Reagents
[0089] Hexadecanol: Jiangxi Alpha Hi-Tech Pharmaceutical Co., Ltd., purity > 99%;
[0090] Octadecanol: Jiangxi Alpha Hi-Tech Pharmaceutical Co., Ltd., purity >99%;
[0091] Food grade ethanol: Henan Xinheyang Alcohol Co., Ltd., content not less than 95% (V / V).
[0092] Medicinal anhydrous ethanol: Nanjing Chemical Reagent Co., Ltd., relative density 0.790-0.793.
[0093] Temperature control effect: The temperature control effect is characterized by whether melting occurs at 35°C and the melting time. The melting time unit is s / cm 3 , 20-60s indicates good thermal stability.
[0094] Foam quality: judged by the uniform density of the foam and the size of the bubbles. The foam is uniformly dense, uniform in size, has no large bubbles, and does not collapse quickly after being sprayed, which is considered to be of good quality.
[0095] Example 1
[0096] Preparation method: Heat 18g hexadecanol, 12g octadecyl alcohol, 14g fatty alcohol polyoxyethylene ether and 16g propylene glycol in a water bath to 70-80℃ and dissolve them, and stir them evenly to form an initial oil phase; add 700g ethanol to the dissolved initial oil phase and stir them evenly to form a mixed oil phase. Finally, add 240g purified water to the mixed oil phase in a water bath at about 40℃ and under stirring. Fill 40g into a 50mL aerosol aluminum can, seal it, and fill it with 3g propane and butane gas.
[0097] Example 2
[0098] 18 g of hexadecanol, 12 g of vaseline, 14 g of fatty alcohol polyoxyethylene ether, 16 g of propylene glycol, 700 g of ethanol and 240 g of purified water were prepared according to the method of Example 1.
[0099] Example 3
[0100] 18 g of vaseline, 12 g of octadecyl alcohol, 14 g of fatty alcohol polyoxyethylene ether, 700 g of ethanol, 16 g of propylene glycol and 240 g of purified water were prepared according to the method of Example 1.
[0101] Example 4
[0102] 18 g of hexadecanol, 12 g of liquid paraffin, 14 g of fatty alcohol polyoxyethylene ether, 700 g of ethanol, 16 g of propylene glycol and 240 g of purified water were prepared according to the method of Example 1.
[0103] Example 5
[0104] 18 g of liquid paraffin, 12 g of octadecyl alcohol, 14 g of fatty alcohol polyoxyethylene ether, 700 g of ethanol, 16 g of propylene glycol and 240 g of purified water were prepared according to the method of Example 1.
[0105] The above products were tested, and the results are shown in Table 1:
[0106] Table 1
[0107]
[0108] The results showed that the combination of cetyl alcohol and stearyl alcohol can produce good quality foam with good temperature control effect and application feel.
[0109] Example 6
[0110] 15 g of hexadecanol, 10 g of octadecyl alcohol, 5 g of cetostearyl alcohol, 14 g of fatty alcohol polyoxyethylene ether, 700 g of ethanol, 16 g of propylene glycol and 240 g of purified water were prepared according to the method of Example 1.
[0111] Example 7
[0112] 12 g of hexadecanol, 8 g of octadecyl alcohol, 10 g of behenyl alcohol, 14 g of fatty alcohol polyoxyethylene ether, 700 g of ethanol, 16 g of propylene glycol and 240 g of purified water were prepared according to the method of Example 1.
[0113] Example 8
[0114] 8 g of dodecanol, 16 g of hexadecanol, 6 g of octadecyl alcohol, 14 g of fatty alcohol polyoxyethylene ether, 700 g of ethanol, 16 g of propylene glycol and 240 g of purified water were prepared according to the method of Example 1.
[0115] Example 9
[0116] 18 g of hexadecanol, 12 g of stearyl alcohol, 14 g of polyoxyethylene lauryl ether, 700 g of ethanol, 26 g of propylene glycol and 230 g of purified water were prepared according to the method of Example 1.
[0117] The above three products were tested and compared, and the results are shown in Table 2:
[0118] Table 2
[0119] Test items Example 6 Example 7 Example 8 Example 9 Foam quality good good Good, and the foam is more delicate good Temperature control effect 40s 55s 20s 30s Apply feeling Good moisturizing Good moisturizing Good moisturizing Good moisturizing
[0120] The results show that adding other primary alcohols can also form products with good foam quality, good temperature control effect and good moisturizing effect. Different primary alcohols will have different effects on the temperature control effect. Adding dodecanol will make the foam more delicate and the temperature control effect better. Cetearyl alcohol will make the foam more delicate and uniform, and docosanol will make the foam softer.
[0121] Example 10
[0122] 22 g of hexadecanol, 8 g of octadecyl alcohol, 14 g of fatty alcohol polyoxyethylene ether, 700 g of ethanol, 16 g of propylene glycol and 240 g of purified water were prepared according to the method of Example 1.
[0123] Four volunteers were recruited to compare the effects (skin feel, moisturizing effect) of the product of Example 10 with the disposable gel and 75% alcohol spray on the market. The results are shown in Table 3:
[0124] Table 3
[0125]
[0126] The results of comparison of the use effects show that the foaming agent of the present invention not only contains ethanol content that can achieve a disinfection effect, but also can replenish the oil dissolved by ethanol, thereby moisturizing and protecting the skin and preventing problems such as dry skin and cracking caused by the foaming agent.
[0127] discuss
[0128] The concentration of ethanol in ethanol disinfectant must reach a relatively high concentration, preferably 70-80% (v / v). At the same time, ethanol is volatile and can be dangerous at high temperatures. Therefore, there are only two ways to add ethanol to the emulsion. One is to add ethanol after the emulsification is completed and the temperature is lowered; the other is to add ethanol before the emulsification reaction, but the emulsification reaction can only be carried out under low temperature conditions.
[0129] However, those skilled in the art know that when the amount of ethanol added to the emulsion exceeds 50% (v / v), the emulsification system is destroyed, the product is stratified and precipitated, and cannot be used. Therefore, ethanol needs to be added before the emulsification operation, i.e., low-temperature emulsification.
[0130] The addition of ethanol can reduce the system temperature in a large amount. Therefore, the oil phase components participating in the emulsification in the emulsification reaction must be able to maintain a stable state under a low temperature system. After a large number of screenings, the present invention finds that only the oil phase that is soluble in ethanol can maintain a stable state. Therefore, the primary condition for the selection of the oil phase component is that it can be soluble in ethanol. At the same time, since the components that can form a film at room temperature are mainly oil phase components, excellent film forming properties are also one of the conditions for the screening of the oil phase component. The present invention uses a specific two-component or three-component oil phase component, and further forms an emulsion suitable for preparing a foaming agent of the present invention by compounding with other components.
[0131] All documents mentioned in the present invention are cited as references in this application, just as each document is cited as reference individually. In addition, it should be understood that after reading the above teachings of the present invention, those skilled in the art can make various changes or modifications to the present invention, and these equivalent forms also fall within the scope defined by the claims attached to this application.
Claims
1. An emulsion, characterized in that Based on its total weight, the emulsion comprises: Ethanol 50-80 parts by weight; 2-10 parts by weight of oil phase components; 0.5-5 parts by weight of foaming and emulsifying ingredients; 0.1-20 parts by weight of alcohol solvent; and Purified water 5-40 parts by weight; And in the emulsion, the final content of ethanol is 70-75wt%; The foaming and emulsifying component is fatty alcohol polyoxyethylene ether; The alcohol solvent is selected from the group consisting of pentaerythritol, ethylene glycol, propylene glycol, glycerol, PEG200, PEG300, or a combination thereof; and The oil phase component comprises a combination of hexadecanol and stearyl alcohol, wherein (1) In the oil phase, the weight ratio of hexadecanol to stearyl alcohol is 1:0.3-0.7, the sum of hexadecanol and stearyl alcohol accounts for 60-85wt% of the total weight of the oil phase, and the oil phase components further include one or more substances selected from the group consisting of lauryl alcohol, tetradecanol, behenyl alcohol, or a combination thereof; or (2) The oil phase is a combination of hexadecanol and stearyl alcohol, wherein the weight ratio of hexadecanol to stearyl alcohol is 1:0.6-0.
7.
2. The emulsion according to claim 1, characterized in that The emulsion is composed of: 8g of dodecanol, 16g of hexadecanol, 6g of octadecyl alcohol, 14g of fatty alcohol polyoxyethylene ether, 700g of ethanol, 16g of propylene glycol and 240g of purified water.
3. The emulsion according to claim 1, characterized in that The foaming and emulsifying component is polyoxyethylene lauryl ether.
4. The emulsion according to claim 1, characterized in that The content of the oil phase component is 3 wt %, based on the total weight of the emulsion.
5. The emulsion according to claim 1, characterized in that The emulsion is composed of: 12 g of hexadecanol, 8 g of stearyl alcohol, 10 g of behenyl alcohol, 14 g of fatty alcohol polyoxyethylene ether, 700 g of ethanol, 16 g of propylene glycol and 240 g of purified water.
6. The emulsion according to claim 1, characterized in that The alcohol solvent is propylene glycol.
7. A foaming agent, characterized in that: The foaming agent is obtained by filling the emulsion according to any one of claims 1 to 6 and adding a propellant.
8. A method for preparing the emulsion according to any one of claims 1 to 6, characterized in that: The method steps include: (1) mixing the oil phase component, the foaming and emulsifying component, and the alcohol solvent to form an initial oil phase; (2) adding ethanol to the initial oil phase and mixing evenly to form a mixed oil phase; (3) Purified water is added to the mixed oil phase for emulsification to form a uniform emulsion.
9. A method for preparing a foaming agent as claimed in claim 7, characterized in that: The method comprises the steps of: providing the emulsion as claimed in any one of claims 1 to 6, filling and charging the propellant, thereby obtaining the foaming agent.
10. Use of the emulsion according to any one of claims 1 to 6 or the foaming agent according to claim 7 in the preparation of a disinfecting and moisturizing dual-effect temperature-controlled foam disinfectant.
Citation Information
Patent Citations
Pumped foam containing alcohol
CN101083908A
Temperature control foaming agent for external use, making method thereof and application thereof
CN104490782A
Novel foaming agent
CN107137352A
