A miticidal composition

Abstract

The present invention relates to a composition for controlling mites, which comprises a compound of formula (I) and at least one other compound (B). The composition for controlling mites according to the present invention has an excellent effect on controlling Tetranychidae, Eriophyidae, Ixodidae mites, their larvae and eggs. Compound of formula (I).

Description

TECHNICAL FIELD

[0001] The present application relates to a kind of acaricidal composition and its use for preventing or controlling mite, especially the use for preventing or controlling mite and its larva and egg. BACKGROUND

[0002] In recent years, the loss caused by phytophagous mites is more and more serious. Mites usually live in a hidden way or exist in a state of immobility in a safe place. Chemical control is an important means for preventing and controlling pests in agriculture. When chemical agents cannot guarantee complete coverage of leaves, its control effect on mites is limited. It is necessary to find acaricides that can penetrate into plants and then transfer to appropriate sites.

[0003] The compound of formula (I) is known from WO2011 / 078081. It is described therein that it can be used for controlling pests, mites, hygiene pests, stored product pests, clothing pests, house pests and the like harmful organisms on agricultural crops. In particular, it has excellent activity against mites which are harmful to agricultural crops, hygiene aspects.

[0004]

[0005] The compound of formula (I)

[0006] However, it is not known whether the compound of formula (I) in combination with specific insecticides can exert a synergistic effect for preventing or controlling harmful organisms, in particular mites and their larvae and eggs. SUMMARY

[0007] The present application aims to solve the above problems and provides an acaricidal composition.

[0008] The acaricidal composition of the present application is achieved by the following technical scheme:

[0009] An acaricidal composition, which comprises a compound of formula (I) and at least one other compound (B) selected from the following:

[0010] (B)-1 fluacrypyrim,

[0011] (B)-2 clofentezine,

[0012] (B)-3 chloropropylate,

[0013] (B)-4 amitraz,

[0014] (B)-5 diafenthiuron,

[0015] (B)-6 ethoxycarbazine,

[0016] (B)-7 afoxolaner.

[0017] The acaricidal composition of the present application has an activity which is significantly higher than the sum of the activities of the individual active ingredients. There is an unexpected, true synergistic effect, rather than merely an additive effect.

[0018] The synergistic effect is particularly pronounced when the compound of formula (I) and the other compound (B) are present in the acaricidal composition of the present application in a specific weight ratio. The weight ratio of the compound of formula (I) and the compound (B) in the composition can vary within a wide range.

[0019]

[0020] Preference is given to combinations of the compound of formula (I) with (B) -2- thiachopon, (B) -3- zeta-cyanidin, (B) -4-amitraz, (B) -5-butoxycarbene.

[0021] The acaricidal composition of the present application can be formulated into a form which can be adopted by a pesticide, such as an emulsifiable concentrate, a water-soluble suspension, an oil-soluble suspension, a dry powder for seed treatment, a suspension for seed treatment, a water-dispersible granule, a wettable powder, a suspoemulsion, a smoke, a coated granule, an extruded granule, an aqueous emulsion, a microcapsule suspension, a microcapsule suspension-suspension, a dry suspension, an ultra-low volume liquid, a soluble powder, a granule, an aerosol, and the like.

[0022] As the carrier used when a solid formulation is made, there can be used, for example, vegetable powder (e.g., soybean powder, starch, grain powder, wood powder, bark powder, sawdust, walnut shell powder, bran, cellulose powder, coconut shell, corn cob, and tobacco stem granules, residues after extracting plant essence, etc.), paper, sawdust, pulverized synthetic resin, etc., synthetic polymer of synthetic resin, clay (e.g., kaolin, bentonite, acid clay, etc.), talc, silica (e.g., diatomaceous earth, silica sand, mica, hydrous silicic acid, calcium silicate), activated carbon, natural mineral (pumice, attapulgite, and zeolite, etc.), calcined diatomaceous earth, sand, plastic medium (e.g., polyethylene, polypropylene, polyvinylidene chloride, etc.), inorganic mineral powder of potassium chloride, calcium carbonate, calcium phosphate, etc., chemical fertilizer of ammonium sulfate, ammonium phosphate, urea, ammonium chloride, etc., soil fertilizer, which can be used alone or in combination of two or more.

[0023] As the carrier used when a liquid formulation is made, there can be used, for example, water, isopropyl alcohol, butyl alcohol, ethylene glycol, methyl ethyl ketone, diisobutyl ketone, cyclohexanone, mineral oil, xylene, solvent naphtha, dimethylformamide, dimethyl sulfoxide, vegetable oil, animal oil, etc.

[0024] For the purpose of obtaining a uniform and stable form, a surfactant can be added at the time of formulation. For example, there can be mentioned, for example, a fatty alcohol polyoxyethylene ether, a polyoxyethylene alkyl aryl ether, a polyoxyethylene higher fatty acid ester, a phosphate ester of a polyoxyethylene alcohol or phenol, a fatty acid ester of a polyhydric alcohol, a naphthalene sulfonic acid polymer, a lignin sulfonate, a comb-like branched copolymer of a high molecule, a butyl naphthalene sulfonate, an alkyl aryl sulfonate, a sodium alkyl sulfosuccinate, an oil, a fatty alcohol condensed with ethylene oxide, a polyacrylate of an alkyl taurate, a protein hydrolysate, a suitable oligosaccharide or polymer, for example, based on ethylene monomer alone, acrylic acid, polyoxyethylene and / or polyoxypropylene, or a combination thereof with, for example, a (poly)alcohol or a (poly)amine.

[0025] Optionally, other additional components, for example, a protective colloid, a binder, a thickener, a thixotropic agent, a penetrant, a stabilizer, a masking agent, can also be contained at the time of formulation.

[0026] At the time of formulation of the composition of the present application, the content of the compound of formula (I) and the compound (B) is preferably 0.01 to 90% by weight, more preferably 0.05 to 85% by weight.

[0027] The acaricidal composition is used for the purpose of preventing or controlling mites and their larvae and eggs.

[0028] The acaricidal composition is used for the purpose of preventing or controlling mites of the families Tetranychidae, Eriophyidae, Ixodidae.

[0029] The acaricidal composition is used for the purpose of preventing or controlling Tetranychus urticae, Panonychus citri, Tetranychus cinnabarinus, Acaphis gossypii, Haemaphysalis longicornis.

[0030] The acaricidal composition is used for the purpose of treating seeds to prevent the seeds from being invaded by mites.

[0031] The acaricidal composition is used for the purpose of applying to soil and / or directly to soil in contact with the roots of a plant or soil suitable for the growth of a plant to prevent the invasion of soil mites.

[0032] A method for preventing or controlling mites and their larvae and eggs, the acaricidal composition is used for the purpose of target useful plants, target mites or their environment, the propagation material of target useful plants.

[0033] A method for preventing or controlling mites and their larvae and eggs, the acaricidal composition is applied to seeds, target useful plants or soil in which plants grow or soil suitable for the growth of plants.

[0034] A method for preventing or controlling mites and their larvae and eggs, the acaricidal composition is applied to soil and / or directly to soil in contact with the roots of a plant or soil suitable for the growth of a plant before germination, after germination or before and after germination of seeds.

[0035] The acaricidal composition of the present application not only includes a ready-to-use form which can be applied to the object to be treated by means of a suitable device such as a spraying or dusting device, but also includes a concentrated commercial composition which needs to be diluted before application to the object.

[0036] The acaricidal composition of the present application can be applied in the form of a combination of its active ingredient compounds or in the form of a combination of commercial preparations of appropriate dosages.

[0037] The acaricidal composition of the present application can be applied without dilution or after dilution with water.

[0038] The acaricidal composition of the present application has an effect of killing adult, nymph, larva and egg, and thus can be used for the control of pests, mites, sanitary pests, stored grain pests, clothing pests, and house pests attached to crops.

[0039] In particular, the acaricidal composition of the present application can effectively control mites and the like which are harmful to crops and sanitation. The acaricidal composition of the present application is suitable for the prevention or control of the following mites:

[0040] Tetranychidae: Tetranychus urticae, Tetranychus viennensis, Tetranychus cinnabarinus, Panonychus citri, Panonychus ulmi, Eotetranychus geniculatus, Eotetranychus pruni, Eotetranychus sexmanaculatus, Eotetranychus smithi, Eotetranychus uncatus, Eotetranychus boreus, Oligonychus hondoensis, Oligonychus ilicis, Oligonychus karamatus, Panonychus mori, Tenuipalpus zhizhilashviliae, Tetranychus kanzawai, Tuckerella pavoniformis, Brevipalpus lewisi, Brevipalpus obovatus, Brevipalpus phoenicis, Bryobia praetiosa, Bryobia rubrioculus, Dolichotetranychus floridanus, and the like;

[0041] Ixodidae: Haemaphyxalis longicornis, Haemaphysalis japonica, Boophilus microplus, Dermacentor reticulatus, Dermacentor taiwanensis, Haemaphysalis flava, Ixodes ovatus, Ixodes persulcatus, Dermacentor reticulatus, and the like;

[0042] Mites belonging to the family Eriophyidae: Calacarus carinatus, Aculops lycopersici, Aculops pelekassi, Aculus schlechtendali, Aceria paradianthi, Calepitrimerus vitis, Colomerus vitis, Epitrimerus pyri, Eriophes kuko, Aceria tulipae, Eriophyes chibaensis, Acaphylla theavagrans, Aculus fockeui, and the like;

[0043] Mites belonging to the family Astigmata: Acarus siro, Aleuroglyphus ovatus, Carpoglyphus lactis, Lardoglyphus konoi, Rhizoglyphus echinopus, Rhizoglyphus robini, Tyrophagus putrescentiae, Tyrophagus similis, and the like;

[0044] Mites belonging to the family Tarsonemidae: Phytonemus pallidus, Polyphagotarsonemus latus, Tarsonemus bilobatus, Tarsonemus waitei, and the like;

[0045] Mites belonging to the family Eupodidae: Penthaleus erythrocephalus, Penthaleus major, and the like;

[0046] In addition, there are also drug-resistant mites which are resistant to the mite-controlling agents known in the past.

[0047] The mite-controlling composition of the present application is particularly suitable for controlling mites belonging to the families Tetranychidae, Eriophyidae, Ixodidae, and their larvae and eggs.

[0048] The acaricidal composition of the present application is particularly suitable for use in the control of Tetranychus urticae, Panonychus citri, Panonychus mori, Bemisia argentifolii, Haemaphysalis longicornis and its larvae and eggs.

[0049] The acaricidal composition of the present application exhibits unexpectedly high preventive or control activity against mites and their larvae and eggs in the treatment of plants, seeds, soil in which plants grow. The plants can be exemplified by stems and leaves of plants, flowers of plants, fruits of plants, etc.

[0050] Due to the multi-generation and adaptability of mites, resistance to mites is developed in a relatively short period of time. The acaricidal composition of the present application has superior permeability and exhibits excellent control effect against mites and their larvae and eggs. The acaricidal composition of the present application has excellent control effect against mites and their larvae and eggs at a low dosage.

[0051] The acaricidal composition of the present application combines fast-acting and long-acting effects and allows effective pest control at a reduced dosage rate of the active ingredient. The acaricidal composition of the present application reduces or avoids adverse environmental or toxicological effects.

[0052] The acaricidal composition of the present application can be applied to seeds, plants, or soil in which plants grow or soil suitable for plant growth. The acaricidal composition of the present application can be applied in any desired manner, for example, seed coating, soil drenching, and / or direct furrow application, and / or foliar spraying.

[0053] Therefore, the present application provides a method for controlling mites and their larvae and eggs, comprising applying the acaricidal composition of the present application to seeds, target useful plants, or soil in which plants grow or soil suitable for plant growth.

[0054] The acaricidal composition of the present application can be applied to soil before germination, after germination, or before and after germination, and / or directly to soil in contact with plant roots or soil suitable for plant growth.

[0055] The method for preventing soil mites and protecting seedling roots and shoots from soil and foliar mites by contacting seeds with an effective amount of the acaricidal composition of the present application before sowing and / or after priming can also be used. Seeds treated with the acaricidal composition of the present application can be stored, managed, sown, and cultivated.

[0056] The acaricidal composition of the present application not only includes ready-to-use compositions that can be applied to plants, seeds, soil in which plants grow using suitable devices, but also includes commercially available concentrates that must be diluted with water before application.

[0057] The present application also provides a method for protecting useful crops from attack by mites and their larvae and eggs, which comprises applying the active ingredient compound of formula (I) in combination, separately or sequentially with the compound (B). In the case of separate application, the order usually has no influence on the result of the control measures.

[0058] The activity of the acaricidal composition of the present application is significantly higher than the sum of the activities of the individual active ingredients. There is an unexpected, true synergistic effect, not just an additive effect of the effects.

[0059] The synergistic effect is particularly pronounced when the compound of formula (I) and the other compound (B) are present in the acaricidal composition of the present application in a specific weight ratio. DETAILED DESCRIPTION

[0060] Biological test examples:

[0061] Test 1: Oviposition test against eggs of Panonychus citri

[0062] The technical material of the compound of formula (I) and the compound (B) is dissolved in acetone to prepare a single-agent stock solution, and then diluted with an aqueous solution containing 0.1% Tween-80 to the desired concentration.

[0063] The leafhoppers loaded with the same day mite eggs are taken, and the eggs on the leafhoppers are counted under a microscope. The leafhoppers are immersed in a certain concentration of the liquid medicine for 5-15 seconds, and then incubated in a humid environment. The treated mite eggs and leafhoppers are incubated under normal conditions. Each treatment is repeated 4 times, and a blank control is set. When the blank control is completely hatched, the eggs that have not hatched are considered dead. After the test is completed, the hatching inhibition rate is calculated.

[0064] Hatching inhibition rate = [(hatching rate of control eggs - hatching rate of treated eggs) / hatching rate of control eggs] x 100%

[0065] In addition, the theoretical hatching inhibition rate (%) can be calculated by the Colby formula. When the hatching inhibition rate (%) is higher than the theoretical hatching inhibition rate (%), the composition of the present application has a synergistic effect. The theoretical mortality rate (%) according to the Colby formula is shown in parentheses in Tables 1-6.

[0066] Table 1

[0067]

[0068] Table 2

[0069]

[0070] Table 3

[0071]

[0072] Table 4

[0073]

[0074] Table 5

[0075]

[0076] Table 6

[0077]

[0078] Formulation Example:

[0079] Example 1 40% compound of formula (I) + 5% tetrasul phermable powder

[0080] Compound of formula (I) 40%

[0081] tetrasul 5%

[0082] alkyl naphthalene sulfonate 5%

[0083] white carbon black 10%

[0084] kaolin make up to 100%

[0085] The above ingredients are mixed and ground through a micronizer to give 40% compound of formula (I) + 5% tetrasul phermable powder

[0086] Example 2 30% compound of formula (I) + 3% fenpyroxymate emulsifiable concentrate

[0087] Compound of formula (I) 30%

[0088] fenpyroxymate 3%

[0089] polyoxyethylene alkyl allyl ether 7%

[0090] calcium dodecylbenzene sulfonate 3%

[0091] dimethyl formamide 30%

[0092] Solvesso TM 200 make up to 100%

[0093] The above ingredients are mixed and stirred until a clear homogeneous phase is obtained to give 30% compound of formula (I) + 3% fenpyroxymate emulsifiable concentrate.

[0094] Example 3 12.5% compound of formula (I) + 12.5% amitraz emulsifiable concentrate

[0095] Compound of formula (I) 12.5%

[0096] amitraz 12.5%

[0097] Ethoxylated castor oil 3%

[0098] Calcium dodecylbenzenesulphonate 2%

[0099] N-methyl pyrrolidone 25%

[0100] Solvesso TM 200 q.s. to 100%

[0101] Mix the above ingredients and stir until a clear homogeneous phase is obtained to give a 12.5% of the compound of formula (I) + 12.5% formetanate emulsifiable concentrate.

[0102] Example 4 10% of the compound of formula (I) + 50% diafenthiuron water dispersible granules

[0103] The compound of formula (I) 10%

[0104] Diafenthiuron 50%

[0105] Sodium lignosulphonate 4%

[0106] Sodium dodecyl sulphate 3%

[0107] White carbon 6%

[0108] Kieselguhr q.s. to 100%

[0109] Mix the above ingredients and pass through an air-jet mill to give a wettable powder. Add a quantity of water and mix to extrude the material. Dry and sieve to give 10% of the compound of formula (I) + 50% diafenthiuron water dispersible granules.

Claims

1. The use of an acaricidal composition for the prevention or control of eggs of the citrus paris mite, characterized in that, The composition contains a compound of formula (I). ， And another compound (B) selected from the following: (B)-6 etoxazole, (B)-7 cyprodinil; the weight ratio of the compound of formula (I) and compound (B)-6 is 10:1 to 1:1; the weight ratio of the compound of formula (I) and compound (B)-7 is 10:1 to 2:

1.

2. The use according to claim 1, characterized in that, The weight ratio of compound (I) to compound (B)-6 is 5:1 to 1:

1.

3. The use according to claim 1, characterized in that, The weight ratio of compound (I) and compound (B)-6 is 2.5:1 to 1:

1.

4. The use according to claim 1, characterized in that, The weight ratio of compound (I) and compound (B)-7 is 8:1 to 2:

1.

5. The use according to claim 1, characterized in that, The weight ratio of compound (I) and compound (B)-7 is 4:1 to 2:

1.

6. The use according to claim 1, characterized in that, The acaricide composition of claim 1 is used on a target useful plant, a target mite or its environment, or the propagation material of the target useful plant.

7. The use according to claim 1, characterized in that, The acaricide composition of claim 1 is applied to seeds, the target useful plant, or the soil in which the plant grows or soil suitable for plant growth.

8. The use according to claim 1, characterized in that, The acaricide composition of claim 1 is applied to the soil before, after, or before and after seed germination and / or directly to the soil in contact with the plant roots or to soil suitable for plant growth.

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