A behavioral detection device for testing the herd behavior of mice

Abstract

The present invention belongs to the field of behavioral technology for testing mice, and particularly relates to a behavioral detection device for testing the herd behavior of mice, comprising a detection box body, a demonstration cavity for storing demonstration mice, and an experimental cavity for storing mice to be subjected to behavioral experiments, wherein the detection box body is divided into a left cavity and a right cavity, a left one-way electromagnetic door is provided between the demonstration cavity and the left cavity, a right one-way electromagnetic door is provided between the demonstration cavity and the right cavity, the experimental cavity and the demonstration cavity are separated by a front transparent observation plug plate, the experimental cavity is a narrow passage with an opening at the top, the left and right side panels, the back panel and the bottom panel of the experimental cavity are opaque, a limiting device is provided in the experimental cavity, and a motor installation box for placing a motor is provided on the left and right sides of the detection box body. The behavioral detection device has a simple structure, an easy-to-implement detection process, and can better explore the herd behavior of mice.

Description

Technical Field

[0001] The invention belongs to the technical field of behavioral testing of mice, and in particular relates to a behavioral testing device for testing the herd behavior of mice. Background Art

[0002] When we make decisions, we are often influenced by social norms, which leads to changes in cognition and even decision-making. This phenomenon has always been a research topic of interest to neuroscientists. In recent years, research on how social norms affect cognitive and decision-making neural mechanisms has become increasingly popular, and conformity, as a typical phenomenon of social norms affecting individual cognitive processes, has gradually attracted the attention of neuroscientists, who have begun to study the relevant neuroscience mechanisms behind it. Conformity is the behavior of matching attitudes, beliefs, and behaviors with group norms or like-minded people. This tendency to conform occurs in small groups and / or the entire society, and may be caused by subtle unconscious influences (susceptible psychological states) or direct and overt social pressure. The study of conformity behavior helps neuroscientists and related psychology researchers understand how the cognitive processes of individuals in society or groups are affected by group or social social norms, and finally affect other components in the group in turn.

[0003] As an emerging research direction, the study of the neuroscience of conformity is an excellent entry point to discover how social norms affect the neural mechanisms of cognition and decision-making. Based on related research, future studies can further explore how social influence affects perception and decision-making standards, so as to better understand the neural mechanisms behind high-level cognitive processes. These studies may help provide us with guidance on how to better manage personal decision-making and promote change and improvement in society.

[0004] In the past, most studies on the impact of social norms on cognition or decision-making were based on the use of non-invasive methods to collect data on human brain activity in a specific social task. However, in order to deeply study the neural mechanisms of these phenomena, neuroscience researchers need to directly observe or operate the nervous system, introduce more precise control environments and conditions, and eliminate interference factors. Using mice, rats, and monkeys to establish animal models similar to the research problems is the basis for neuroscience researchers to further explore the neural mechanisms of the herd phenomenon. Among them, mice, as an animal model, are widely used in neuroscience research. As mammals, mice are similar to the human nervous system, especially the structure and function of brain regions and neural circuits. Therefore, they can simulate human cognitive processes well. Compared with using large mammals or primates to establish models, using mice to establish models is cheaper and more suitable for some more economical research projects.

[0005] At the same time, in the study of neuroscience animal models, behavioral experiments are often the first step. Neuroscience researchers first observe and analyze the behavioral performance of animals to determine whether animals have high-level cognitive processes similar to those of humans, evaluate their cognitive functions, and then analyze related brain areas. However, based on the current behavioral research on mouse conformity, the existing technology does not have an experimental device for exploring mouse conformity.

[0006] As an emerging research direction, there is still a blank in the relevant experimental equipment for conformity behavior. In the past, the experimental equipment used to test the decision-making behavior of mice was complex in structure, difficult to use, and had high production costs. The corresponding maintenance costs were also high. The experimental schemes designed based on these devices often required a lot of time to train experimental mice. These problems caused neuroscience researchers to spend a lot of money and time in their research, which hindered the progress of the study of the neural mechanism of conformity behavior. Therefore, for standardized research experiments on conformity behavior, it is urgent to develop an experimental device with a simple structure, easy to use, and intuitive and reliable experimental schemes designed.

[0007] Therefore, it is extremely urgent to develop a behavioral detection device that is easy to train mice and is used to test the herd behavior of mice. Summary of the invention

[0008] The purpose of the present invention is to overcome the deficiencies of the prior art, and specifically discloses a behavioral detection device for testing the herd behavior of mice. The behavioral detection device has a simple structure, an easy detection process, and can better explore the herd behavior of mice.

[0009] In order to achieve the above technical objectives, the present invention is implemented according to the following technical solutions:

[0010] The behavioral detection device for testing the herd behavior of mice described in the present invention comprises a detection box body, a demonstration cavity for storing demonstration mice and an experimental cavity for storing mice to be subjected to behavioral experiments, the tops of the detection box body, the demonstration cavity and the experimental cavity are all open, the detection box body is divided into a left cavity and a right cavity, a left one-way electromagnetic door that can be opened one-way from the demonstration cavity to the left cavity is provided between the demonstration cavity and the left cavity, and a right one-way electromagnetic door that can be opened one-way from the demonstration cavity to the right cavity is provided between the demonstration cavity and the right cavity, the experimental cavity and the demonstration cavity are separated by a front transparent observation plug plate, the experimental cavity is a narrow and long channel with an opening on the top, the left and right side panels, the back plate and the bottom plate of the experimental cavity are opaque, a limiting device is provided in the experimental cavity, and a motor mounting box for placing a motor is provided on the left and right sides of the detection box body.

[0011] As a further improvement of the above technology, the limiting device in the experimental chamber is two limiting rods respectively fixed on the left and right inner walls of the experimental chamber. The limiting rods are fixed horizontally. The limiting device can better control the mice in the experimental chamber to move within a specified range and prevent the mice from jumping high and escaping.

[0012] As a further improvement of the above technology, the motor mounting box is in a U-shaped groove shape.

[0013] As a further improvement of the above technology, the left one-way electromagnetic door is movably hinged to the side door frame of the left cavity through hinges and reset springs and can be reset, and the right one-way electromagnetic door is movably hinged to the side door frame of the right cavity through a hinge chain and a reset spring and can be reset.

[0014] As a further improvement of the above technology, matrix-type flexible thin film pressure sensors are laid on the bottom of the detection box body, the bottom of the demonstration chamber and the bottom of the experimental chamber.

[0015] As a further improvement of the above technology, an electronic control device is also included, which is electrically connected to the motor, the left one-way electromagnetic door and the right one-way electromagnetic door, and is used to control the opening and closing actions of the left one-way electromagnetic door and the right one-way electromagnetic door of the detection box body, and is used to record the experimental data of the herd behavior at each operation time in the experiment. At the same time, a matrix flexible film pressure sensor is added, and the detailed behavioral data of the experimental target is transmitted to the computer in conjunction with optical sensors such as industrial cameras.

[0016] Compared with the prior art, the present invention has the following beneficial effects:

[0017] The behavioral detection device of the present invention has a simple structure and is easy to operate. It can obtain better behavioral experimental results in accordance with current behavioral norms, and can select the control mode and expand the control mechanism according to experimental requirements to facilitate future customization needs. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] The present invention is described in detail below with reference to the accompanying drawings and specific embodiments:

[0019] Figure 1 It is a structural schematic diagram (stereoscopic diagram) of the behavioral detection device of the present invention;

[0020] Figure 2 1 is a schematic diagram (top view) of the structure of the behavioral detection device of the present invention;

[0021] Figure 3 It is a schematic diagram of the structure of the left one-way electromagnetic door and the right one-way electromagnetic door in the present invention;

[0022] Figure 4 is the above Figure 3 A top view of

[0023] Figure 5 is the above Figure 3 An enlarged schematic diagram of the right one-way electromagnetic door;

[0024] Figure 6 It is a front view of the experimental chamber in the present invention. DETAILED DESCRIPTION

[0025] like Figures 1 to 6 As shown, the behavioral detection device for testing the herd behavior of mice of the present invention comprises a detection box body 1, a demonstration chamber 2 for storing demonstration mice and an experimental chamber 3 for storing mice to be subjected to behavioral experiments. The tops of the detection box body 1, the demonstration chamber 2 and the experimental chamber 3 are all open. The detection box body 1 is divided into a left cavity 11 and a right cavity 12. A left one-way electromagnetic door 4 is provided between the demonstration chamber 2 and the left cavity 11, which can be opened one-way from the demonstration chamber 2 to the left cavity 11. A There is a right one-way electromagnetic door 5 which can be opened one-way from the demonstration chamber 2 to the right cavity 12. The electromagnetic locks of the left one-way electromagnetic door 4 and the right one-way electromagnetic door 5 are correspondingly installed in the keyhole 20. The experimental chamber 3 and the demonstration chamber 2 are separated by a front transparent observation plug plate 31. The experimental chamber 3 is a narrow passage with an opening on the top. The left and right side panels 33, the back panel 32 and the bottom panel 34 of the experimental chamber 3 are all opaque. A limiting device is provided in the experimental chamber 3. The left and right sides of the detection box body 1 are provided with motor mounting boxes 7 for placing motors.

[0026] The limiting device in the experimental chamber 3 is two limiting rods 6 respectively fixed on the left and right inner walls of the experimental chamber 3. The limiting rods 6 are fixed horizontally. The limiting device can better limit the movement of mice in the experimental chamber 3 within a specified range to prevent mice from jumping high and escaping.

[0027] like Figure 1 As shown, in order to conveniently place the motor, the motor mounting box 7 is in a U-shaped groove.

[0028] like Figures 3 to 5 As shown, the left one-way electromagnetic door 4 is movably hinged to the side door frame 10 of the left cavity 11 through a hinge 8 and a reset spring 9 and can be reset. Similarly, the right one-way electromagnetic door 5 is movably hinged to the side door frame 10 of the right cavity 12 through a hinge chain 8 and a reset spring 9 and can be reset.

[0029] In addition, in order to achieve better experimental results, matrix flexible film pressure sensors are laid at the bottom of the detection box body 1, the bottom of the demonstration chamber 2 and the bottom of the experimental chamber 3, which can cooperate with optical sensors such as industrial cameras to transmit the detailed behavioral data of the experimental target to the computer.

[0030] The present invention also includes a control device, which is electrically connected to the motor, the left one-way electromagnetic door 4, and the right one-way electromagnetic door 5, and is used to control the opening and closing actions of the left one-way electromagnetic door 4 and the right one-way electromagnetic door 5 of the detection box body 1, and is used to record the experimental data of the herd behavior at each operation time in the experiment. At the same time, a matrix flexible film pressure sensor is added, and optical sensors such as industrial cameras are used to transmit the detailed behavioral data of the experimental target to a computer.

[0031] The following specifically describes the experimental process of the behavioral detection device for testing the herd behavior of mice according to the present invention:

[0032] (1) In the experiment, the one-way switch door is locked with an electromagnetic lock, and the mouse to be tested is placed in the experimental chamber 3 of the narrow passage, forcing it to only observe the front transparent observation plug plate 31. The front transparent observation plug plate 31 and the opaque black back plate 32 are used at the back of the narrow passage to ensure that the mouse is in the narrow passage and can observe the situation in front of it. After the experiment starts, the front transparent plug plate is pulled out for testing.

[0033] (2) During the experiment, a control device is used to manipulate the various components in the test box, and the control device will record the time of each operation in the experiment. In addition, the matrix-type flexible film pressure sensor laid on the bottom of the test box body 1, the bottom of the demonstration chamber 2, and the bottom of the experimental chamber 3 will return the pressure position data of the mouse. Combined with the data saved by optical sensors such as industrial cameras, it is convenient for subsequent experimental analysis. The entire experimental process is simple, fast, and easy to implement.

[0034] The present invention is not limited to the above-mentioned embodiments. Any changes or modifications to the present invention do not depart from the spirit and scope of the present invention. If these changes and modifications fall within the scope of the claims and equivalent technologies of the present invention, the present invention is also meant to include these changes and modifications.

Claims

1. A behavioral detection device for testing the herd behavior of mice, characterized in that: It includes a detection box body, a demonstration cavity for storing demonstration mice and an experimental cavity for storing mice to be subjected to behavioral experiments. The tops of the detection box body, the demonstration cavity and the experimental cavity are all open. The detection box body is divided into a left cavity and a right cavity. A left one-way electromagnetic door that can be opened one-way from the demonstration cavity to the left cavity is provided between the demonstration cavity and the left cavity. A right one-way electromagnetic door that can be opened one-way from the demonstration cavity to the right cavity is provided between the demonstration cavity and the right cavity. The experimental cavity and the demonstration cavity are separated by a front transparent observation plug-in plate. The experimental cavity is a narrow passage with an opening on the top. The left and right side panels, the back panel and the bottom panel of the experimental cavity are opaque. A limiting device is provided in the experimental cavity. Motor mounting boxes for placing motors are provided on the left and right sides of the detection box body.

2. The behavioral detection device for testing the herd behavior of mice according to claim 1, characterized in that: The limiting device in the experimental chamber is two limiting rods respectively fixed on the left and right inner side walls of the experimental chamber, and the limiting rods are fixed in the horizontal direction.

3. The behavioral detection device for testing the herd behavior of mice according to claim 1, characterized in that: The motor mounting box is in the shape of a U-shaped groove.

4. The behavioral detection device for testing the herd behavior of mice according to claim 1, characterized in that: The left one-way electromagnetic door is movably hinged to the side door frame of the left cavity through a hinge and a reset spring and can be reset. The right one-way electromagnetic door is movably hinged to the side door frame of the right cavity through a hinge chain and a reset spring and can be reset.

5. The behavioral detection device for testing the herd behavior of mice according to claim 1, characterized in that: The bottom of the detection box body, the bottom of the demonstration cavity and the bottom of the experimental cavity are all paved with matrix-type flexible film pressure sensors.

6. The behavioral detection device for testing the herd behavior of mice according to claim 5, characterized in that: A control device is also included, which is electrically connected to the motor, the left one-way electromagnetic door, and the right one-way electromagnetic door, and is used to control the opening and closing actions of the left one-way electromagnetic door and the right one-way electromagnetic door of the detection box body, and is used to record the experimental data of the herd behavior at each operation time in the experiment.

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