An artificial valve device

Abstract

The present invention relates to the technical field of medical devices, and discloses an artificial valve device. The artificial valve device includes a stent, and the stent includes a first mesh structure layer, a second mesh structure layer, and a third mesh structure layer. The first mesh structure layer, the second mesh structure layer, and the third mesh structure layer are distributed in sequence along the direction from the blood outflow end to the blood flow inflow end. The length of the support rod portion of the first mesh structure layer, the length of the support rod portion of the second mesh structure layer, and the length of the support rod portion of the third mesh structure layer decrease in sequence. The artificial valve device also includes a valve, and the valve is connected to the stent. In the above manner, the present invention can improve the axial positioning performance of the artificial valve device and is conducive to preventing paravalvular leakage.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and in particular to an artificial valve device. Background Art

[0002] The aortic valve is a tricuspid valve located between the left ventricular outflow tract and the ascending aorta. The main function of the valve is to maintain efficient left ventricular ejection. Many pathological conditions affect the valve, resulting in various abnormalities. Aortic valve disease is a common disease in the clinical practice of cardiologists and cardiac surgeons, mainly due to its high incidence in the elderly population. Treatments for severe aortic valve disease include surgical repair or replacement of the valve. Standard surgical treatment strategies include aortic valve repair, valve protection techniques, and aortic valve replacement techniques.

[0003] Aortic valve disease includes aortic stenosis and aortic regurgitation, and in most cases, both coexist. Aortic stenosis accounts for the majority of aortic valve diseases, with an incidence of 1-2% in people over 65 years old and 4% in people over 85 years old.

[0004] The technical principle of transcatheter aortic valve replacement (TAVR) is to compress a fixed stent with an artificial valve sewn on it and load it into a delivery system, which is then delivered to the aortic valve along an access route (such as an artery) and released, squeezing the diseased aortic valve to the side of the artificial valve. The artificial aortic valve is then fixed at the aortic valve to replace the diseased aortic valve.

[0005] However, current artificial valve stents have poor sealing effects on the diseased area and a higher risk of paravalvular leakage. Summary of the Invention

[0006] In view of this, the main technical problem to be solved by the present invention is to provide an artificial valve device, which can improve the axial positioning performance of the artificial valve device and help prevent paravalvular leakage.

[0007] To solve the above technical problems, the present invention adopts a technical solution: providing an artificial valve device. The artificial valve device includes a stent, the stent having a blood flow inflow end and a blood flow outflow end, the blood flow inflow end and the blood flow outflow end being arranged relative to each other along a preset direction; the stent includes a first mesh structure layer, a second mesh structure layer, and a third mesh structure layer, the first mesh structure layer, the second mesh structure layer, and the third mesh structure layer being distributed in sequence from the blood flow outflow end to the blood flow inflow end; the first mesh structure layer, the second mesh structure layer, and the third mesh structure layer each include at least two support rods, the at least two support rods being distributed in sequence along a preset circumferential direction, wherein the length of the support rods of the first mesh structure layer, the length of the support rods of the second mesh structure layer, and the length of the support rods of the third mesh structure layer decrease in sequence, wherein the preset direction is perpendicular to the plane defined by the preset circumferential direction; the artificial valve device also includes a valve, which is connected to the stent.

[0008] In one embodiment of the present invention, the ratio of the length of the support rods of the first mesh structure layer, the length of the support rods of the second mesh structure layer, and the length of the support rods of the third mesh structure layer is 5-7:2-3:1-2.

[0009] In one embodiment of the present invention, the stent further includes a fourth mesh structure layer, which is closer to the blood flow inflow end relative to the third mesh structure layer, and includes at least two support rods.

[0010] In one embodiment of the present invention, the length of the support rods of the fourth network structure layer is greater than the length of the support rods of the third network structure layer.

[0011] In one embodiment of the present invention, the ratio of the support rod lengths of the first mesh structure layer, the second mesh structure layer, the third mesh structure layer, and the fourth mesh structure layer is 5-7.6:2-2.3:1:1.8.

[0012] In one embodiment of the present invention, the ratio of the length of the supporting rod portion of the second mesh structure layer to the length of the supporting rod portion of the third mesh structure layer is 2-3:1.

[0013] In one embodiment of the present invention, the first mesh structure layer, the second mesh structure layer and the third mesh structure layer all further include a connecting portion, and a connecting portion is provided between any two adjacent support rod portions in each mesh structure layer, and the connecting portion includes a first connecting rod portion and a second connecting rod portion connected; the first connecting rod portion and the second connecting rod portion connected in the first mesh structure layer form a first angle, the first connecting rod portion and the second connecting rod portion connected in the second mesh structure layer form a second angle, and the first connecting rod portion and the second connecting rod portion connected in the third mesh structure layer form a third angle.

[0014] In one embodiment of the present invention, the first angle, the second angle, and the third angle are all between 95° and 120°.

[0015] In one embodiment of the present invention, the second angle and the third angle are both greater than the first angle.

[0016] In one embodiment of the present invention, at least two connecting portions are provided between at least some of the adjacent two supporting rod portions in the first mesh structure layer.

[0017] The present invention has the following beneficial effects: Different from the prior art, the present invention provides an artificial valve device. The artificial valve device includes a stent, the stent comprising a first reticular structure layer, a second reticular structure layer, and a third reticular structure layer, wherein the first reticular structure layer, the second reticular structure layer, and the third reticular structure layer are sequentially arranged in a direction from the blood outflow end toward the blood inflow end. The lengths of the support rods of the first reticular structure layer, the support rods of the second reticular structure layer, and the support rods of the third reticular structure layer decrease in sequence.

[0018] In this way, during stent expansion, the first, second, and third support rods shorten in a step-by-step manner toward the blood outflow end. In particular, when a balloon dilatation catheter is used to deliver an artificial valve device, the stent is expanded using a balloon, with the first support rod expanding before the second and third support rods. This allows the second and third support rods to move sequentially toward the blood outflow end during stent expansion, achieving a step-by-step collapse. This not only effectively controls the collapse of the stent during expansion, which helps improve the stent's positioning performance, but also allows the stent portions where the second and third support rods are located to effectively fit within the affected area, thereby effectively preventing paravalvular leakage. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] The accompanying drawings are incorporated into and constitute a part of the specification, illustrate embodiments consistent with the present invention, and together with the description, serve to explain the principles of the present invention. In addition, these drawings and the description are not intended to limit the scope of the present invention in any way, but rather to illustrate the concept of the present invention for those skilled in the art by reference to specific embodiments.

[0020] Figure 1 1 is a schematic structural diagram of an embodiment of an artificial valve device of the present invention;

[0021] Figure 2 1 is a schematic diagram of the expanded structure of the first embodiment of the stent of the present invention;

[0022] Figure 3 is a schematic diagram of the deployed structure of the second embodiment of the stent of the present invention;

[0023] Figure 4 2 is a schematic diagram of the expanded structure of an embodiment of the first mesh structure layer of the present invention. DETAILED DESCRIPTION

[0024] To further clarify the objectives, technical solutions, and advantages of the present invention, the following will provide a clear and complete description of the technical solutions in the embodiments of the present invention, in conjunction with the embodiments of the present invention. It should be understood that the described embodiments are only a portion of the embodiments of the present invention, not all of them. All other embodiments derived by persons of ordinary skill in the art based on the embodiments of the present invention without inventive effort are within the scope of protection of the present invention. The following embodiments and features thereof may be combined with each other unless there is a conflict.

[0025] In order to solve the technical problem of poor axial positioning performance of artificial valve stents during expansion in the prior art, one embodiment of the present invention provides an artificial valve device. The artificial valve device includes a stent, the stent has a blood flow inflow end and a blood flow outflow end, and the blood flow inflow end and the blood flow outflow end are arranged relative to each other along a preset direction; the stent includes a first mesh structure layer, a second mesh structure layer and a third mesh structure layer, and the first mesh structure layer, the second mesh structure layer and the third mesh structure layer are distributed in sequence from the blood flow outflow end to the blood flow inflow end; the first mesh structure layer, the second mesh structure layer and the third mesh structure layer each include at least two support rods, and the at least two support rods are distributed in sequence along a preset circumferential direction, wherein the length of the support rod of the first mesh structure layer, the length of the support rod of the second mesh structure layer and the length of the support rod of the third mesh structure layer decrease in sequence, wherein the preset direction is perpendicular to the plane defined by the preset circumferential direction; the artificial valve device also includes a valve, and the valve is connected to the stent. The following is a detailed description.

[0026] See also Figure 1 , Figure 1 It is a structural schematic diagram of an embodiment of an artificial valve device of the present invention.

[0027] In one embodiment, the artificial valve device can be used in transcatheter aortic valve replacement, etc. Specifically, the artificial valve device can be compressed and loaded into a delivery system, and then delivered to the aortic valve along the access route and released at the aortic valve, so that the artificial valve device expands to squeeze the diseased aortic valve to the side of the artificial valve device, and then the artificial valve device is anchored at the aortic valve to replace the diseased aortic valve.

[0028] Specifically, the artificial valve device includes a stent 10 and a valve 20. The stent 10 is used to anchor the valve 20 to the patient's site. To accommodate transcatheter aortic valve replacement, the stent 10 of this embodiment is capable of both compression and expansion. Specifically, the stent 10 can be compressed for loading into a delivery system and expanded at the patient's site to anchor the stent 10 to the patient's site. The valve 20 is connected to the stent 10 and can be anchored to the patient's site along with the stent 10 to replace the diseased aortic valve.

[0029] Furthermore, the valve 20 can be connected to the stent 10 by suturing, welding, etc., wherein the suturing method will be described in detail below.

[0030] In one embodiment, the stent 10 has a blood flow inlet end A and a blood flow outlet end B, and the blood flow inlet end A and the blood flow outlet end B are arranged along a preset direction (eg, Figure 1 The support 10 includes a plurality of mesh structure layers (such as the first mesh structure layer, the second mesh structure layer, the third mesh structure layer, the fourth mesh structure layer, etc.) distributed layer by layer along a preset direction. The mesh structure layer includes a connecting portion 11 and at least two support rod portions 12. The at least two support rod portions 12 are arranged along a preset circumferential direction (such as Figure 1 As shown by the arrow O in the middle, the same below) are distributed in sequence, and a connecting portion 11 is provided between any two adjacent support rods 12. Among them, the preset direction is perpendicular to the plane defined by the preset circumferential direction.

[0031] like Figure 1 As shown, the valve 20 includes leaflets 21 and a skirt 22. The stent 10 is arranged along a preset circumferential direction to form a receiving area C. The leaflets 21 are arranged in the receiving area C to replace the diseased original heart valve. The skirt 22 is arranged at the blood flow inlet end A of the stent 10, and wraps the inner and outer sides of the blood flow inlet end A of the stent 10 to prevent paravalvular leakage. The valve 20 is connected to the stent 10 through a fixing hole. The connection method includes suturing, welding, bonding, etc. The fixing hole can be rectangular or circular, etc., which is not limited here. In one embodiment, the leaflets 21 are sutured to the stent 10.

[0032] For example, there are three leaflets 21, each leaflet 21 is provided with a protrusion adapted to the fixing hole, the protrusion of each leaflet 21 is inserted into the fixing hole, and each leaflet 21 is sutured to the stent 10 in sequence by suture thread. In this embodiment, the fixing portion 1212 has at least two fixing holes, and the leaflet 21 is sutured to the stent 10 through the at least two fixing holes. Figure 1 shown.

[0033] Furthermore, a gasket may be added during the suturing of the leaflet 21 and the fixing hole to expand the area of the suturing position, thereby facilitating the suturing operation. The skirt 22 and the stent 10 may be joined by one or more methods such as suturing with suture thread and welding.

[0034] The stent 10 can be made of a metal material. Optionally, the stent 10 can be made of at least one of stainless steel, cobalt-chromium alloy, and other materials. Preferably, the stent 10 can be made of MP35N alloy, which comprises 35% nickel, 35% cobalt, 20% chromium, and 10% molybdenum by weight. This reduces the material usage of the stent 10, helps reduce the compressed volume of the stent 10, and enables the stent 10 to have excellent pressure resistance, fatigue resistance, and corrosion resistance.

[0035] Furthermore, the stent 10 can be integrally formed from a metal tube by laser molding or welding. For example, the excess portion of a metal tube of appropriate specifications can be removed by laser cutting, leaving the metal stent 10. After removing residue through processes such as grinding and pickling, the stent 10 is heat treated to improve its mechanical properties. Of course, the stent 10 can also be electrochemically polished to achieve a smoother surface finish and enhanced biocompatibility, thereby improving the success rate of aortic valve replacement.

[0036] See also Figure 2 , Figure 2 1 is a schematic diagram of the expanded structure of the first embodiment of the stent of the present invention.

[0037] In one embodiment, the stent 10 may adopt a three-layer mesh structure design, that is, the stent 10 includes three mesh structure layers.

[0038] Specifically, the stent 10 includes a first mesh structure layer 15, a second mesh structure layer 16, and a third mesh structure layer 17. The first mesh structure layer 15, the second mesh structure layer 16, and the third mesh structure layer 17 are sequentially distributed along the direction from the blood outflow end B to the blood inflow end A.

[0039] The first mesh structure layer 15 includes a first connecting portion 151 and a first supporting rod portion 152. The first supporting rod portions 152 are sequentially spaced along a predetermined circumferential direction. A first connecting portion 151 is provided between any two adjacent first supporting rod portions 152. The first connecting portion 151 is located closer to the blood outflow end B relative to the first supporting rod portions 152. The second mesh structure layer 16 includes a second connecting portion 161 and a second supporting rod portion 162. The second supporting rod portions 162 are sequentially spaced along a predetermined circumferential direction. A second connecting portion 161 is provided between any two adjacent second supporting rod portions 162. The second connecting portion 161 is located closer to the blood outflow end B relative to the second supporting rod portions 162. The second connecting portion 161 connects to the first supporting rod portion 152. The third mesh structure layer 17 includes a third connecting portion 171 and a third support rod portion 172. The third support rod portions 172 are spaced apart in sequence along a preset circumferential direction. A third connecting portion 171 is provided between any two adjacent third support rod portions 172. The third connecting portion 171 is close to the blood flow outflow end B relative to the third support rod portion 172. The third connecting portion 171 is connected to the second support rod portion 162.

[0040] Furthermore, the stent 10 further includes a fourth connecting portion 181. A fourth connecting portion 181 is further provided between any two adjacent third support rods 172. The fourth connecting portion 181 is closer to the blood flow inflow end A relative to the third support rods 172.

[0041] Please continue reading Figure 2 In one embodiment, the length S2 of the second support rod portion 162 in the preset direction is greater than the length S3 of the third support rod portion 172 in the preset direction. Thus, during the expansion process of the stent 10, due to the larger size of the second support rod portion 162, the second support rod portion 162 moves less in the preset direction, which helps to ensure the positioning effect of the stent 10 during expansion, that is, to ensure that the stent 10 is accurately anchored to the patient's site, and can reduce the risk of the second support rod portion 162 deviating from the patient's site due to the larger movement of the second support rod portion 162.

[0042] Optionally, the ratio of the length S2 of the second support rod portion 162 in the preset direction to the length S3 of the third support rod portion 172 in the preset direction is 2-3:1. Thus, during the expansion of the stent 10, the movement of the second support rod portion 162 in the preset direction can be further controlled, further ensuring the positioning effect of the stent 10 during expansion.

[0043] Please continue reading Figure 2In one embodiment, the lengths of the support rods of the first mesh structure layer 15, the support rods of the second mesh structure layer 16, and the support rods of the third mesh structure layer 17 decrease in sequence. Specifically, the length S1 of the first support rod 152 in the predetermined direction, the length S2 of the second support rod 162 in the predetermined direction, and the length S3 of the third support rod 172 in the predetermined direction decrease in sequence.

[0044] Through the above-described method, during the expansion process of the stent 10, the first support rod portion 152, the second support rod portion 162, and the third support rod portion 172 shorten in a step-by-step manner toward the blood outflow end B. In particular, when a balloon dilatation catheter is used to deliver an artificial valve device, the stent 10 is expanded using a balloon, wherein the position of the first support rod portion 152 is expanded before the positions of the second support rod portion 162 and the third support rod portion 172. As the stent expands, the second support rod portion 162 and the third support rod portion 172 move sequentially toward the blood outflow end B, achieving a step-by-step collapse. In this way, not only can the collapse of the stent 10 during expansion be well controlled, which is conducive to improving the positioning performance of the stent 10, but it can also control the portion of the stent 10 where the second support rod portion 162 and the portion of the stent 10 where the third support rod portion 172 are located to effectively cooperate with the diseased area, thereby effectively preventing paravalvular leakage.

[0045] Furthermore, the ratio of the length S1 of the first support rod 152 in the preset direction, the length S2 of the second support rod 162 in the preset direction, and the length S3 of the third support rod 172 in the preset direction is 5-7:2-3:1-2. In this way, during the expansion process of the stent 10, the collapse of the stent 10 during expansion can be further controlled, further ensuring the positioning effect of the stent 10 during expansion.

[0046] See also Figure 3 , Figure 3 2 is a schematic diagram of the expanded structure of the second embodiment of the stent of the present invention.

[0047] In one embodiment, the stent 10 further includes a fourth reticular structure layer 18, which is located closer to the blood flow inflow end A than the third reticular structure layer 17. Specifically, the fourth reticular structure layer 18 includes fourth connecting portions 181 and fourth support rods 182. The fourth support rods 182 are sequentially spaced along a predetermined circumferential direction, with a fourth connecting portion 181 provided between any two adjacent fourth support rods 182. The fourth connecting portion 181 is located closer to the blood flow outflow end B than the fourth support rods 182, and is connected to the third support rods 172.

[0048] Furthermore, the stent 10 further includes a fifth connecting portion 191. A fifth connecting portion 191 is further provided between any two adjacent fourth support rods 182. The fifth connecting portion 191 is closer to the blood flow inflow end A relative to the fourth support rods 182.

[0049] In one embodiment, the length of the support rods of the fourth network structure layer 18 is greater than the length of the support rods of the third network structure layer 17. Specifically, the length S4 of the fourth support rods 182 of the fourth network structure layer 18 in the preset direction is greater than the length S3 of the third support rods 172 of the third network structure layer 17 in the preset direction.

[0050] In the above manner, since there is no obvious difference in the sizes of the third connecting portion 171 and the fourth connecting portion 181, the length of the fourth support rod portion 182 is greater than the length of the third support rod portion 172, that is, the single mesh area of the fourth mesh structure layer 18 is larger, which is beneficial to the expansion of the fourth mesh structure layer 18 to form a trumpet-like structure, and thus is beneficial to preventing paravalvular leakage.

[0051] Furthermore, the ratio of the length S1 of the first support rod 152 in the preset direction, the length S2 of the second support rod 162 in the preset direction, the length S3 of the third support rod 172 in the preset direction, and the length S4 of the fourth support rod 182 in the preset direction is 5-7.6:2-2.3:1:1.8. This facilitates the stepwise shortening of the first support rod 152, the second support rod 162, and the third support rod 172 toward the blood outflow end B, and also facilitates the expansion of the fourth mesh structure layer 18, thereby preventing paravalvular leakage.

[0052] Please continue reading Figure 2 In one embodiment, for the case where the stent 10 of the above embodiment includes the first mesh structure layer 15, the second mesh structure layer 16, and the third mesh structure layer 17, the first connecting rod portion and the second connecting rod portion of the first connecting portion 151 form a first angle θ1, the first connecting rod portion and the second connecting rod portion of the second connecting portion 161 form a second angle θ2, and the first connecting rod portion and the second connecting rod portion of the third connecting portion 171 form a third angle θ3. The first angle θ1, the second angle θ2, and the third angle θ3 are all between 95° and 120°.

[0053] The first angle θ1, the second angle θ2, and the third angle θ3 are the opening angles of the first connection portion 151, the second connection portion 161, and the third connection portion 171 after the stent 10 is expanded. Through the above-described method, the first angle θ1, the second angle θ2, and the third angle θ3 are reasonably set, which can ensure that the stent 10 has sufficient anchoring force to ensure that the stent 10 is reliably anchored in the patient's site, and can also ensure that the stent 10 has sufficient supporting force to reliably support the valve 20 in the patient's site.

[0054] Furthermore, both the second angle θ2 and the third angle θ3 are greater than the first angle θ1. As described above, when a prosthetic valve device is delivered using a balloon dilatation catheter, the first support rod portion 152 expands before the second support rod portion 162 and the third support rod portion 172. Therefore, the first support rod portion 152 does not need to have strong rigidity. A smaller first angle θ1 means that the first connecting portion 151 is less open, which helps weaken the rigidity of the first support rod portion 152 and facilitates the expansion of the portion of the stent 10 where the first support rod portion 152 is located.

[0055] It should be noted that the angle formed by the first connecting rod portion and the second connecting rod portion can be understood as the angle formed by the extension direction of the first connecting rod portion and the extension direction of the second connecting rod portion.

[0056] See also Figure 4 , Figure 4 2 is a schematic diagram of the expanded structure of an embodiment of the first mesh structure layer of the present invention.

[0057] In one embodiment, at least two connecting portions (i.e., first connecting portions 151) are provided between at least some of the adjacent support rods (i.e., first support rods 152) in the first mesh structure layer 15. In other words, compared to adjacent mesh structure layers, some of the first support rods 152 in the first mesh structure layer 15 of this embodiment are missing. This increases the area of individual meshes in the first mesh structure layer 15, facilitating percutaneous coronary intervention (PCI) procedures, for example, by facilitating the passage of instruments through the meshes in the first mesh structure layer 15.

[0058] Furthermore, in the present invention, unless otherwise expressly specified or limited, terms such as "connected," "connected," and "stacked" should be interpreted broadly. For example, they may refer to fixed or detachable connections, or integration; they may refer to direct connection or indirect connection through an intermediate medium; they may refer to internal communication between two elements or interaction between two elements. Those skilled in the art will understand the specific meanings of the above terms in the present invention based on specific circumstances.

[0059] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit it. Although the present invention has been described in detail with reference to the above embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the above embodiments, or replace some or all of the technical features therein with equivalents. However, these modifications or replacements do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of the present invention.

Claims

1. An artificial valve device, characterized in that: include: The stent has a blood flow inflow end and a blood flow outflow end, wherein the blood flow inflow end and the blood flow outflow end are arranged relative to each other along a preset direction; The stent comprises a first mesh structure layer, a second mesh structure layer and a third mesh structure layer, wherein the first mesh structure layer, the second mesh structure layer and the third mesh structure layer are sequentially distributed along a direction from the blood outflow end toward the blood inflow end; The first mesh structure layer, the second mesh structure layer, and the third mesh structure layer each include at least two support rods, and the at least two support rods are sequentially spaced apart along a preset circumferential direction, wherein the lengths of the support rods of the first mesh structure layer, the second mesh structure layer, and the third mesh structure layer decrease in sequence, and the preset direction is perpendicular to a plane defined by the preset circumferential direction; a valve connected to the stent; A fourth reticular structure layer, the fourth reticular structure layer is closer to the blood flow inflow end relative to the third reticular structure layer, the fourth reticular structure layer includes at least two support rod portions, and the length of the support rod portion of the fourth reticular structure layer is greater than the length of the support rod portion of the third reticular structure layer.

2. The artificial valve device according to claim 1, characterized in that The ratio of the length of the supporting rod portion of the first network structure layer, the length of the supporting rod portion of the second network structure layer, and the length of the supporting rod portion of the third network structure layer is 5-7:2-3:1-2.

3. The artificial valve device according to claim 1, characterized in that The ratio of the length of the support rod portion of the first mesh structure layer, the length of the support rod portion of the second mesh structure layer, the length of the support rod portion of the third mesh structure layer, and the length of the support rod portion of the fourth mesh structure layer is 5-7.6:2-2.3:1:1.

8.

4. The artificial valve device according to any one of claims 1 to 3, characterized in that: The ratio of the length of the supporting rod portion of the second network structure layer to the length of the supporting rod portion of the third network structure layer is 2-3:

1.

5. The artificial valve device according to any one of claims 1 to 3, characterized in that: The first mesh structure layer, the second mesh structure layer, and the third mesh structure layer each further include a connecting portion, wherein the connecting portion is provided between any two adjacent support rod portions in each mesh structure layer, and the connecting portion includes a first connecting rod portion and a second connecting rod portion that are connected to each other; The first connecting rod portion and the second connecting rod portion connected in the first mesh structure layer form a first angle, the first connecting rod portion and the second connecting rod portion connected in the second mesh structure layer form a second angle, and the first connecting rod portion and the second connecting rod portion connected in the third mesh structure layer form a third angle.

6. The artificial valve device according to claim 5, characterized in that The first angle, the second angle and the third angle are all between 95° and 120°.

7. The artificial valve device according to claim 5, characterized in that The second angle and the third angle are both greater than the first angle.

8. The artificial valve device according to any one of claims 1 to 3, characterized in that: At least two connecting portions are provided between at least some of the adjacent two supporting rod portions in the first mesh structure layer.

Images