64 results about "Perivalvular Leak" patented technology

The invention discloses an involvement type prosthetic heart valve stent with barbs and a preparation method thereof, and belongs to the technical field of involvement type medical devices. The stent is an elastic stent which can stretch or retract in a radial direction, and comprises a tubular structural part and a skirt-shaped open structural part; the diameter of the skirt-shaped open structural part is greater than that of the tubular structural part; the tubular structural part and the skirt-shaped open structural part are coaxially and fixedly connected; barks are also arranged in the stent; the barbs extend from the tubular structural structure to the skirt-shaped open structural part and are tilted to the outer side of the stent. The stent can extend and retract in the radial direction so as to facilitate the mounting, the transporting and the releasing in involvement treatment; the stent structure is matched with the physiological structure of a natural valve, has a certain self-positioning function, and is convenient to position and release quickly and accurately; the barbs can penetrate into the tissues around the valve after the heart valve is planted into a specific position so as to achieve a positioning effect; displacement and perivalvular leakage are not easily caused after the valve is released.

An oval valve for use in transcutaneous aortic (TAVI) or mitral valve implantation or for direct access valve implantation. The oval leaflet frame or stent provides a better seal with the oval native annulus to reduce perivalvular leaks. The valve leaflets are a bileaflet configuration to provide improved leaflet coaptation independent of the amount of ovality of the native valve annulus. The bileaflet configuration is less dependent upon the diameter and perimeter of the native valve annulus and provides leaflet coaptation without intravalvular leakage.

The invention discloses an artificial heart valve prosthesis and an artificial heart valve stent. The artificial heart valve stent comprises an outer-layer bracket and an inner-layer bracket, whereinthe inner-layer bracket is fixedly connected with the outer-layer bracket, the outer-layer bracket is provided with an outer-layer inflow channel structure and an outer-layer outflow channel structure, the outer-layer inflow channel structure and the outer-layer outflow channel structure are axially connected, the inner-layer bracket is provided with an inner-layer inflow channel structure and aninner-layer outflow channel structure and is located on the inner side of the outer-layer bracket in the radial direction, the inner-layer inflow channel structure and the inner-layer outflow channelstructure are connected in the axial direction, and an anchoring structure is arranged on the outer side of the inner-layer bracket. According to the artificial heart valve prosthesis and the artificial heart valve stent, the inner-layer bracket bears the artificial valve leaflet, and is high in rigidity and small in diameter, so that the area of the artificial valve leaflet can be reduced, the height required by the opening and closing movement of the valve leaflet is reduced, and the service life of the valve leaflet is prolonged; the outer-layer bracket is weak in relative rigidity, large in diameter and capable of preventing perivalvular leakage; and the anchoring structure is connected with the inner-layer bracket, and the anchoring force for preventing the prosthetic valve from moving is mainly borne by the inner-layer bracket with high rigidity, so that the service life of the stent is prolonged.

The invention discloses an intrusive type heart valve prosthesis and a preparation method thereof, and belongs to the technical field of intrusive type medical apparatuses. The intrusive type heart valve prosthesis comprises an elastic bracket, a covering film and at least two valves, wherein the elastic bracket can extend and retract along the radial direction, the covering film is sewed onto the inner wall or the outer wall of the bracket, the valves are arranged in a cavity of the bracket, the lower edge of each valve is sewed onto the covering film, the adjacent sides of the two adjacent valves are mutually spliced, and the side edges of the valves are sewed onto the bracket. The intrusive type heart valve prosthesis has the advantages that the function of natural valves can be well replaced; by adopting the elastic bracket, the valve structure can be conveniently loaded into a conveying device, and can also be conveniently released to the target position to be tightly combined with the surrounding tissues of the target position; the bracket is coated by the covering film, so the surrounding leakage of the valves is effectively prevented; the bionic degree of the sewing structure of the valve and the covering film is high, the natural valves can be well simulated, and the function of the natural valves is replaced; the structure is stable and firm, the durability and firmness are realized, the elastic extending and retracting requirements in the loading and release processes can be met, and the damage is avoided.

The invention discloses a support for an involvement type artificial cardiac valve and a preparation method thereof and belongs to the technical field of involvement type medical apparatus and instruments. The support is an elastic support capable of extending and contracting in the radial direction, the support comprises a tubular structure part and a skirt-shaped opening structure part, the diameter of the skirt-shaped opening structure part is larger than that of the tubular structure part, and the tubular structure part and the skirt-shaped opening structure part are fixedly connected in a coaxial mode. Due to the fact that the support is capable of extending and contracting in the radial direction, so that the support is convenient to install, convey and release in the involvement treatment, the support and a natural valve are fitted with each other in physiologic structure, the support has a certain self-location function, the support is convenient to locate and release rapidly and accurately, and displacement and perivalvular leakage are not prone to occurring after releasing.

An expandable member that is configured to engage an interior region of a prosthetic valve and capable of transitioning from a pre-deployment configuration at a pre-deployment temperature, where the expandable member is capable of being positioned in the valve at an interior valve region when the valve is disposed in a cardiovascular structure, to a post-deployment configuration when the expandable member is subjected to cardiovascular tissue temperature, where an outer surface region of the valve proximate the interior valve region is placed in intimate contact with host cardiovascular tissue of the cardiovascular structure at a first position and seals perivalvular leaks present at the first cardiovascular structure position.

The invention discloses a conveying system for an involvement type artificial cardiac valve and belongs to the technical field of involvement type medical apparatus and instruments. The conveying system comprises the involvement type artificial cardiac valve and a conveying device thereof, the functions of a natural valve can be well replaced with the valve, the blood can be effectively prevented from backflow through the valve, an elastic support is adopted, the support is convenient to install into the conveying device and release to the objective position rapidly for being combined with tissues around the objective position tightly, a wrapping film is adopted to wrap the support so that the perivalvular leakage can be prevented effectively, the sutured structure of the combination between valve leaflets and the wrapping film is high in bionic degree, the natural valve can be well simulated, the functions of the natural valve can be replaced, the structure is stable, firm and durable, and the valve can adapt to the elastic stretching requirements in the installing and releasing process so that the valve can not be damaged; the conveying device is simple in structure, convenient to use and high in releasing success rate, the valve is applicable to conveying-releasing strategies of the involvement type artificial cardiac valve in various ways, and the involvement type artificial cardiac valve can be released rapidly and accurately.

The invention relates to an aortic valve stent. The aortic valve stent comprises a stent body and a prosthetic valve connected to the stent body, the stent body is of a double-layer stent body and specifically comprises a balloon expanding stent body and a self-expanding stent body, the prosthetic valve is connected to the self-expanding stent body, and after the stent body is conveyed, the self-expanding stent body is located on the inner periphery of the balloon expanding stent body and tightly abuts against the balloon expanding stent body to the outer periphery; the balloon expanding stent body tightly abuts against the aortic valve of the human body to the outer periphery, and an anchoring structure is formed between the balloon expanding stent body and the self-expanding stent body. According to the stent with the prosthetic valve, through the double-layer design, the full expansion and fixation of the aortic valve are ensued, the shape and area in the stent are ensured, and meanwhile, the compliance and support strength of the stent are ensured; the occurrence of perivalvular leakage and central regurgitation is reduced, the diameter of the sheath is not increased, and the risks of vascular complications are avoided.

The invention relates to an aorta valve stent conveying system which comprises a push release device for conveying an aorta valve stent. Particularly, the aorta valve stent conveying system further comprises a special-shaped balloon catheter arranged at the front end of the push release device, the special-shaped balloon catheter comprises a balloon, the balloon is provided with a cylindrical connecting portion and a balloon expanding portion communicated with the cylindrical connecting portion, and the cylindrical connecting portion is connected with the front end of the push release device; according to the design of the balloon, after expansion, a positioning face is formed in the side, close to the cylindrical connecting portion, of the balloon expanding portion, when the aorta valve stent conveying system is in use, the balloon expanding portion of the balloon is located inside a left ventricle outflow tract and tightly fits the bottom of the human aorta valve through the positioning face, and the effects of positioning and reducing and/or resisting valve leakage are achieved.

The invention discloses a conveying device which comprises a guide tube assembly and a control assembly, wherein the control assembly is arranged at the rear end of the guide tube assembly; the control assembly comprises a first control mechanism; the first control mechanism comprises a hollow shell and a limiting unit; the limiting unit comprises a limiting part and a hollow accommodation part; the accommodation part is arranged in the shell; an axial groove and a circumferential groove are formed in the outer surface of the accommodation part; the limiting part penetrates through the shell and is accommodated in the axial groove or the circumferential groove, and then the shell can be axially moved or circumferentially rotated; and the limiting part is further driven by the shell to moveaxially or rotate circumferentially. By adopting the conveying device and a conveying system disclosed by the invention, a first control part is arranged, and a connecting guide tube in the guide tube assembly connected with an implant can be directly controlled to be rapidly switched to circumferential movement from axial movement, so that accurate and reliable implant release positions can be achieved, the implant can be tightly adhered to tissue, and the risk of perivalvular leakage can be reduced.

The invention relates to a heart valve prosthesis and a heart valve prosthesis system. The heart valve prosthesis comprises a valve frame and at least one protruding structure, the protruding structure comprises a protruding part, the protruding part is arranged on the valve frame and protrudes towards the outer side of the valve frame, and the protruding part is constructed to be capable of forming wrinkles when being compressed in the radial direction. After the artificial heart valve is implanted into the human body, the protruding parts in the protruding structures make corresponding contact with the autologous valve ring, the protruding parts can be subjected to the radial compression effect of the autologous valve ring, wrinkles formed by the protruding parts make contact with the autologous valve ring, the number of contact points of the protruding parts and the inner wall of the autologous valve ring can be increased, the adherence can be improved, and the size of the gap formed between the protruding part and the autologous valve ring is reduced, the flow speed of blood flowing through the gap can be reduced, protein in the blood is deposited in the gap, thrombus is formed, the gap can be blocked, and then perivalvular leakage is prevented.

A device (100) for medically sealing a perivalvular leak associated with implanted valves includes a bioresorbable tissue infiltratable sheet (116) for insertion through a perivalvular leak. A filament (122) extending through the sheet (116) is also provided which when pulled causes the sheet (116) to gather around the filament (122) on either side of the perivalvular leak. The gathered position of the sheet (116) may be secured by a series of stops and/or use of a capping member (200).

The invention discloses a novel double-layer occluder which includes an occluder body. A fixer is arranged at the upper end of the occluder body, and a connector is arranged at the lower end of the occluder body. The occluder body is connected to an external conveying steel cable through the connector, the occluder body includes an outer layer and an inner layer which are composed of metal wires,one of the ends of the metal wires of the inner layer and the outer layer are respectively fixed to the fixer, and the other of the ends of the metal wires of the inner layer and the outer layer are respectively fixed to the connector. The novel double-layer occluder has the advantages of good stability, high anatomical adaptability, not prone to hemolysis, and low valve influence, and the closureof paravalvular leak, patent ductus arteriosus and ventricular septal defect by a transcatheter intervention method is completed; the radial support force is high; the instrument structure is compact, red blood cells are not prone to passing, and occluder-related hemolysis is not prone to causing; after the instrument is deformed and fixed, residual parts on and below the paravalvular leak are few, the device is not close to an artificial valve, and the opening and closing of the artificial valve are not prone to influencing; and the damage to an approach blood vessel is small, and blood vessel complications are fewer.

A transcatheter prosthesis includes a stent, a prosthetic valve component, and an anti-paravalvular leakage component. The anti-paravalvular leakage component is coupled to the stent and includes an inner skirt, an outer wrap, a cavity, an opening, and a one-way valve. The inner skirt is disposed on an inner surface of the stent and has an inflow end and a downstream end. The outer wrap is disposed around an outer surface of the stent and has an inflow end coupled to the inflow end of the inner skirt and a downstream end. The cavity is formed between an outer surface of the inner skirt and an inner surface of the outer wrap. An opening is disposed between the inner skirt and the outer wrap. The one-way valve includes a flap at the opening configured to open to allow blood flow into the cavity but prevent blood flow out of the cavity.

A hybrid heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The hybrid heart valve includes a substantially non-expandable, non-compressible prosthetic valve member having a peripheral sealing ring and an expandable stent frame projecting from an inflow end, thereby enabling attachment to the annulus without sutures. The stent frame may be plastically-expandable and may have a thin fabric layer covering its entirety as well as secondary sealing structures around its periphery to prevent paravalvular leaking. Other sealing solutions include interactive steps at the time of valve implant to establish seals around the stent and especially between the stent and the sealing ring of the valve member.

The invention discloses a heart valve stent and a heart valve prosthesis. The heart valve stent comprises a stent main body, which comprises mutually connected grid structure units, wherein the stentmain body is divided into an inflow channel, a transition section and an outflow channel in the axial direction, the inflow channel, the transition section and the outflow channel are connected in sequence, the stent further comprises a limiting structure connected with the stent main body, and the limiting structure is distributed on the outflow channel or the transition section in the circumferential direction, and is provided with a first projection part for limiting the stent from moving from the inflow channel to the outflow channel. According to the invention, the limiting structure is arranged on the outflow channel of the stent, so that the stent can be prevented from moving towards the outflow channel under the scouring of blood flow; the inflow channel of the stent is arranged toadapt to the shape of the native tissue, and the outer skirt edge is arranged in the circumferential direction of the outer side of the inflow channel at the position attached to the native tissue, so that perivalvular leakage can be effectively prevented while the valve is prevented from moving towards the inflow channel; and the size of the inflow channel of the stent can be small so as to effectively prevent atrioventricular block, and the size of the outflow channel can be small so as to reduce the compression on the aorta.

The invention provides an implant conveying device and an implant conveying system. The implant conveying device comprises a conveying assembly, a first control bending pipe and a second control bending pipe. At least one part of the conveying assembly movably penetrates through the first control bending pipe in the axial direction of the first control bending pipe. The first control bending pipe and the conveying assembly movably penetrate through the second control bending pipe in the axial direction of the second control bending pipe and are used for extending out of the far end of the second control bending pipe; the first bending control pipe and the second bending control pipe are configured to control bending respectively; and the extension direction of the conveying assembly is changed along with the bending shapes of the first control bending pipe and the second control bending pipe. By means of the configuration, bending control is conducted on the bending control pipe in a segmented mode, large-angle bending control can be achieved, and the problems that an existing conveying device is difficult to control bending and small in bending control angle are solved. The implant can be safely and accurately released in a narrow space, and the problems of perivalvular leakage and the like in the operation process are reduced.

The invention provides an anchoring device of a heart valve prosthesis and a heart valve prosthesis system.The heart valve prosthesis system comprises the anchoring device and the heart valve prosthesis, the anchoring device comprises an anchoring section and a supporting section which are axially connected with each other, and the anchoring section is provided with an annular first cavity capable of containing the heart valve prosthesis; the supporting section is arranged on one side of the anchoring section in the axial direction, the supporting section comprises at least two elastic wires which are sequentially arranged in the circumferential direction of the anchoring section, one end of each elastic wire is connected with the anchoring section, and the other end of each elastic wire extends in the direction away from the anchoring section. According to the anchoring device, anchoring of the heart valve prosthesis can be achieved through the structure of the preset cavity, the anchoring device does not need to cross an original valve ring in the implanting process, and then perivalvular leakage can be effectively prevented after the heart valve prosthesis is implanted.

The balloon dilatation type interventional valve stent comprises a stent body, a valve leaflet and the wingspan skirt, the wingspan skirt is arranged on the outer side of an outflow channel, a traction suture is connected to the wingspan skirt, one side of the traction suture is connected with the wingspan skirt, and the other side of the traction suture is connected with a skirt on the side of an inflow channel. The traction sutures connected to the interiors of the skirt edges on the inflow channel side are gradually tensioned in the circumferential direction under the action of balloon expansionary force, so that the traction sutures in the wingspan skirt edges are tensioned, the wingspan skirt edges are folded in the axis direction of the stent body, and parts protruding outwards in the radial direction of the stent body are formed. Therefore, the perivalvular leakage is covered or blocked. The structure of the outflow channel is fully utilized, on the premise that the diameter of a conveying system is not increased, an available wingspan skirt structure is added, and the blocking effect of perivalvular leakage is greatly improved. In addition, due to the fact that flexible non-metal materials are used, damage to the heart cannot be increased by an additional structure.