A new coronavirus raman enhanced spectroscopy fingerprint detection device

Abstract

The application discloses a new coronavirus Raman enhanced spectrum fingerprint detection equipment, a detection workbench, a supporting shell is installed on the detection workbench, a detection display mechanism for detecting the new coronavirus is installed in the supporting shell, the detection display mechanism detects the new coronavirus in exhaled gas of a human body and timely displays, and the new coronavirus Raman enhanced spectrum fingerprint detection equipment utilizes the exhaled gas of the human body, if the exhaled gas contains the new coronavirus, the new coronavirus is mixed with a new coronavirus antibody in a filter, the virus is captured, a virus minute group with a special spectrum fingerprint is formed, the molecule group emits a special fingerprint spectrum under irradiation of a laser beam, the spectrum is amplified by a million times, is compared with a spectrum fingerprint stored by an instrument, whether the molecule group contains the new coronavirus can be rapidly judged, the exhaled gas of the human body to be detected is sucked out by a new coronavirus sterilization purifier of the instrument after sterilization, and the exhaled gas is discharged from the machine.

Description

Technical Field

[0001] This invention relates to the field of COVID-19 detection technology, specifically to a COVID-19 Raman-enhanced spectral fingerprint detection device. Background Technology

[0002] The novel coronavirus is a large family of viruses known to cause more serious illnesses such as the common cold, Middle East Respiratory Syndrome (MERS), and Severe Acute Respiratory Syndrome (SARS). The novel coronavirus is a new strain of coronavirus that has never been found in humans before.

[0003] In the process of nucleic acid detection, it is necessary to transfer the solution to be tested and observe the solution to obtain the test results. Most existing transfer processes use a pipette to pick up the solution to be tested and transfer it to the detection chip for detection. However, this method requires a complex mechanical structure to support its implementation. Even if it is implemented, there is still a problem that the transfer process cannot effectively overcome the problem of process contamination. To address this, we propose a Raman enhanced spectral fingerprint detection device for the novel coronavirus. Summary of the Invention

[0004] The purpose of this invention is to provide a Raman-enhanced spectral fingerprint detection device for the novel coronavirus, so as to solve the problems mentioned in the background art.

[0005] To achieve the above objectives, the present invention provides the following technical solution: a COVID-19 SARS-CoV-2 Raman-enhanced spectral fingerprint detection device, comprising:

[0006] The testing workbench is equipped with a support housing, and a detection display mechanism for detecting the novel coronavirus is installed inside the support housing. The detection display mechanism uses exhaled human gas to detect the novel coronavirus inside the gas and display it in a timely manner.

[0007] The tube outlet mechanism is used to replace the air blowing tube at the detection and display mechanism.

[0008] Preferably, the detection and display mechanism includes an antibody tank installed inside the support housing, and the antibody tank contains COVID-19 antibodies;

[0009] The top of the antibody tank is connected to a connecting tube, and the other end of the connecting tube is connected to a transfer cylinder;

[0010] The transfer cylinder is equipped with a filter mechanism inside, and a connecting mechanism is provided at the bottom of the transfer cylinder, which is connected to the air blowing pipe.

[0011] The transfer cylinder has a Raman detection probe running through it, and the Raman detection probe is electrically connected to a spectral fingerprint recognition and display via a signal transmission line. An air purification mechanism is provided on the top of the transfer cylinder.

[0012] Preferably, the filtration mechanism includes a filter installed inside the transfer cylinder, and the filter is used to filter the gas inside the transfer cylinder. Through the provided filtration mechanism, the gas inside the transfer cylinder is filtered.

[0013] Preferably, the connecting mechanism includes an inclined tube whose bottom is connected to the transfer cylinder, an installation tube connected to the top of the inclined tube, a switch closing mechanism on the installation tube, and the installation tube passes through one side of the supporting housing;

[0014] One end of the air blowing pipe is located inside the mounting pipe, and through the provided connecting mechanism, it connects the transfer cylinder and the support shell.

[0015] Preferably, the switch closing mechanism includes a closing shell that communicates with one end of the mounting tube, and the closing shell is in communication with the inclined tube;

[0016] The closed shell has a closing block inside, and a rubber pad is provided on the outside of the closing block. The closing block is connected to the inner wall of the closed shell through the rubber pad on the outside.

[0017] The top of the closing block is provided with a threaded hole, and a lifting screw is threadedly connected to the threaded hole. The top of the lifting screw passes through the top of the closing shell, and the top of the closing shell is provided with a driving component for driving the lifting screw. Through the provided switch closing mechanism, the function of opening and closing the installation tube is realized.

[0018] Preferably, the driving component includes a micro motor mounted on the top of the closed housing, and a first rotating gear is fixedly connected to the output end of the micro motor. A second rotating gear is meshed with the outer side of the first rotating gear, and the second rotating gear is fixedly sleeved on the top of the lifting screw. The driving component is provided to drive the lifting screw.

[0019] Preferably, the air purification mechanism includes an air purifier installed inside the support housing, and the air purifier is equipped with a positioning tube. The air purifier is connected to the top of the transfer cylinder through the positioning tube, thereby purifying the gas inside the transfer cylinder through the air purification mechanism.

[0020] Preferably, the tube outlet mechanism includes a support frame located on the top of the testing workbench, a placement shell is mounted on the support frame, and a closed cover is provided on the top of the placement shell;

[0021] The housing contains multiple air-blowing pipes, and the bottom of the housing has a first outlet. A pipe-discharging plate is slidably connected to the bottom of the first outlet. The pipe-discharging plate has a second outlet that communicates with the first outlet. A material-discharging plate is slidably connected to the bottom of the pipe-discharging plate, and the material-discharging plate has an opening. A pusher for driving the pipe-discharging plate is provided on the support frame. Through the provided pipe-discharging mechanism, the air-blowing pipes can be received.

[0022] Preferably, the bottom of the support frame is equipped with a receiving plate for receiving the falling air pipe, and one end of the receiving plate is provided with a limiting protrusion. The receiving plate serves to receive the air pipe.

[0023] This invention has at least the following beneficial effects:

[0024] This invention utilizes human exhaled air. If it contains the novel coronavirus, it mixes with the novel coronavirus antibody in a filter, capturing the virus and forming a viral molecular cluster with a special spectral fingerprint. This molecular cluster emits a special fingerprint spectrum under laser beam irradiation. This spectrum is magnified millions of times and compared with the spectral fingerprint stored in the instrument. This allows for rapid determination of whether the instrument contains the novel coronavirus molecular cluster. The detected human exhaled air is then absorbed and disinfected by the instrument's novel coronavirus sterilization and purification device before being cleanly discharged from the machine. Attached Figure Description

[0025] Figure 1 This is a schematic diagram of the overall structure of the present invention;

[0026] Figure 2 This is a schematic diagram of the detection workbench structure of the present invention;

[0027] Figure 3 This is a schematic diagram of the internal structure of the supporting shell of the present invention;

[0028] Figure 4 This is a schematic diagram of the antibody tank structure of the present invention;

[0029] Figure 5 For the present invention Figure 4 Enlarged structural diagram of region A in the middle;

[0030] Figure 6 This is a schematic diagram of the shell structure of the present invention;

[0031] Figure 7 This is a schematic diagram of the internal structure of the housing of the present invention;

[0032] Figure 8 This is a schematic diagram of the tube sheet structure of the present invention;

[0033] Figure 9 This is a schematic diagram of the receiving board structure of the present invention;

[0034] Figure 10 This is a schematic diagram of the Raman spectral fingerprint structure of the present invention.

[0035] In the diagram: 1-Detection workbench; 2-Support housing; 3-Detection display mechanism; 31-Antibody solution tank; 32-Connecting tube; 33-Transfer cylinder; 34-Filtering mechanism; 341-Filter; 35-Connecting mechanism; 351-Inclined tube; 352-Mounting tube; 36-Blowing tube; 37-Raman detection probe; 38-Spectral fingerprint recognition and display; 39-Air purification mechanism; 391-Air purifier; 392-Positioning tube; 4-Outlet tube mechanism; 41-Support frame; 41 1-Receiving plate; 42-Placement shell; 43-Closing cover plate; 44-Outlet tube plate; 45-Outlet plate; 46-Pushing component; 461-Electric push rod; 462-Push screw; 463-Rotating gear; 464-Gear chain; 465-Rotating motor; 5-Switch closing mechanism; 51-Closing shell; 52-Closing block; 521-Rubber pad; 53-Lifting screw; 54-Drive component; 541-Micro motor; 542-First rotating gear; 543-Second rotating gear. Detailed Implementation

[0036] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0037] Please see Figure 1-10 Example 1

[0038] A Raman enhanced spectroscopy fingerprint detection device for the novel coronavirus includes: a detection workbench 1, wherein the detection workbench 1 is a Raman detector workbench, and a table and chair for the person being tested are provided on the outside of the detection workbench 1, so that the person being tested can sit on the chair during the test; a support shell 2 is installed on the detection workbench 1, and a detection display mechanism 3 for detecting the novel coronavirus is installed inside the support shell 2; the detection display mechanism 3 uses the exhaled gas of the human body to detect the novel coronavirus in the gas and display it in a timely manner.

[0039] The test results show that the device 3 includes an antibody tank 31 installed inside the support housing 2, and the antibody tank 31 contains COVID-19 antibodies.

[0040] The top of the antibody liquid tank 31 is connected to a connecting tube 32, and the other end of the connecting tube 32 is connected to a transfer cylinder 33;

[0041] The intermediate transfer cylinder 33 is equipped with a filter mechanism 34, which includes a filter 341 installed inside the intermediate transfer cylinder 33. The filter 341 is used to filter the gas inside the intermediate transfer cylinder 33. The bottom of the intermediate transfer cylinder 33 is equipped with a connecting mechanism 35, which includes an inclined tube 351 whose bottom is connected to the intermediate transfer cylinder 33. The top of the inclined tube 351 is connected to an installation tube 352. The installation tube 352 is equipped with a switch closing mechanism 5, and the installation tube 352 passes through one side of the support housing 2. The switch closing mechanism 5 includes a closing shell 51 connected to one end of the installation tube 352, and the closing shell 51 is connected to the inclined tube 351.

[0042] The closed shell 51 has a closing block 52 inside, and a rubber pad 521 is provided on the outside of the closing block 52. The closing block 52 is connected to the inner wall of the closed shell 51 through the rubber pad 521 on the outside.

[0043] The top of the closing block 52 is provided with a threaded hole, and a lifting screw 53 is threadedly connected to the threaded hole. The top of the lifting screw 53 passes through the top of the closing shell 51, and the top of the closing shell 51 is provided with a driving component 54 for driving the lifting screw 53.

[0044] The drive unit 54 includes a micro motor 541 mounted on the top of the closed housing 51, and a first rotating gear 542 is fixedly connected to the output end of the micro motor 541. A second rotating gear 543 is meshed with the outer side of the first rotating gear 542, and the second rotating gear 543 is fixedly sleeved on the top of the lifting screw 53.

[0045] Specific implementation process: In this invention, when the tester blows gas into the transfer cylinder 33 using the air blowing tube 36, a pressure sensor is also provided inside the inclined tube 351 to detect the internal pressure. Subsequently, the micro motor 541 runs, further driving the first rotating gear 542 to drive the second rotating gear 543. While the second rotating gear 543 rotates, it drives the lifting screw 53 to rotate. While the lifting screw 53 rotates, it provides driving force to the closing block 52, further causing the closing block 52 to move down, thereby sealing the top of the inclined tube 351. After the Raman detection probe 37 completes the detection, the air purifier 391 is turned on, thereby purifying the air in the transfer cylinder 33 and the inclined tube 351.

[0046] One end of the air blowing pipe 36 is located inside the mounting pipe 352, and the connecting mechanism 35 is connected to the air blowing pipe 36;

[0047] A Raman detection probe 37 runs through the interior of the transfer cylinder 33, and the Raman detection probe 37 is electrically connected to a spectral fingerprint recognition and display 38 via a signal transmission line. An air purification mechanism 39 is provided on the top of the transfer cylinder 33. The air purification mechanism 39 includes an air purifier 391 installed inside the support housing 2, and a positioning tube 392 is installed on the air purifier 391. The air purifier 391 is connected to the top of the transfer cylinder 33 through the positioning tube 392, so that the positioning tube 392 purifies the gas inside the transfer cylinder 33 through the air purifier 391.

[0048] Specific implementation process: This invention utilizes human exhaled air. If it contains the novel coronavirus, it mixes with novel coronavirus antibodies within filter 341, capturing the virus and forming a viral molecular cluster with a unique spectral fingerprint. This molecular cluster, under laser beam irradiation, emits a special fingerprint spectrum, which is amplified millions of times. By comparing this spectrum with the spectral fingerprint stored in the instrument, it can be quickly determined whether or not it contains novel coronavirus molecular clusters. The detected human exhaled air is then absorbed and disinfected by the instrument's novel coronavirus sterilization and purification device before being cleanly discharged from the machine, as per the instruction manual. Figure 10 This is a Raman spectral fingerprint image.

[0049] The tube outlet mechanism 4 is used to replace the air blowing tube 36 at the detection display mechanism 3. The tube outlet mechanism 4 includes a support frame 41 located on the top of the detection workbench 1. A placement shell 42 is installed on the support frame 41, and a closing cover plate 43 is provided on the top of the placement shell 42.

[0050] The housing 42 contains multiple air blowing tubes 36. In this invention, the air blowing tubes 36 are disposable air blowing tubes 36. The bottom of the housing 42 is provided with a first outlet, and the bottom of the first outlet is slidably connected to an outlet plate 44. The outlet plate 44 is provided with a second outlet communicating with the first outlet. The bottom of the outlet plate 44 is slidably connected to a discharge plate 45, and the discharge plate 45 is provided with an opening. The support frame 41 is provided with a pusher 46 for driving the outlet plate 44. In this invention, the pusher 46 is preferably an electric push rod 461 mounted on the support frame 41. The outlet plate 44 can reciprocate relative to the bottom of the housing 42 by the telescopic movement of the output end of the electric push rod 461.

[0051] The bottom of the support frame 41 is equipped with a receiving plate 411 for receiving the falling air pipe 36, and one end of the receiving plate 411 is provided with a limiting protrusion.

[0052] Specific implementation process: When different people are being tested, since the air blowing pipe 36 is in contact with the mouth of the person being tested, after the previous person has finished using it, the used air blowing pipe 36 needs to be thrown into the trash can. At this time, by the operation of the pusher 46, the air blowing pipe 36 at the outlet plate 44 is further pushed to the opening of the discharge plate 45. Through the second outlet and the opening, it falls onto the receiving plate 411. The next person being tested then takes the air blowing pipe 36 that has fallen onto the receiving plate 411 and further inserts the air blowing pipe 36 into the installation pipe 352. The closing block 52 is then opened to blow gas into the transfer cylinder 33. Example 2

[0053] Based on Embodiment 1: The pusher 46 includes push screws 462 rotatably connected to both ends inside the support frame 41, and the two ends of the two outlet plates 44 are threaded onto the outside of the two push screws 462. A rotating gear 463 is fixedly connected to one end of the push screw 462 located outside the support frame 41, and a gear chain 464 is connected between the two rotating gears 463. A rotary motor 465 is mounted on the support frame 41 to drive the rotating gears 463. Further, the rotary motor 465 rotates forward and backward. The two rotating gears 463 rotate synchronously under the transmission of the gear chain 464, thereby causing the two push screws 462 to rotate synchronously. While the push screws 462 rotate, they provide driving force to the tube plate 44, which in turn enables the tube plate 44 to reciprocate between the placement shell 42 and the discharge plate 45. This allows the air blowing pipe 36, which has fallen to its second outlet, to be moved to the opening and then fall from the opening onto the receiving plate 411. This allows the air blowing pipe 36 to be replaced when different people are inspecting it.

[0054] It should be noted that, in this document, relational terms such as "first" and "second" are used only to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such process, method, article, or apparatus.

[0055] Although embodiments of the invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A Raman-enhanced spectral fingerprint detection device for the novel coronavirus, characterized in that, include: A detection workbench (1) is provided, on which a support housing (2) is installed. Inside the support housing (2) is a detection display mechanism (3) for detecting the novel coronavirus. The detection display mechanism (3) uses exhaled gas to detect the novel coronavirus inside the gas and displays it in a timely manner. A tube outlet mechanism (4) is provided for replacing the air blowing tube (36) at the detection display mechanism (3). The detection and display mechanism (3) includes an antibody liquid tank (31) installed inside the support shell (2), and the antibody liquid tank (31) contains COVID-19 antibodies; the top of the antibody liquid tank (31) is connected to a connecting pipe (32), and the other end of the connecting pipe (32) is connected to a transfer cylinder (33); the transfer cylinder (33) is provided with a filter mechanism (34), and the bottom of the transfer cylinder (33) is provided with a connecting mechanism (35), and the connecting mechanism (35) is connected to an air blowing pipe (36); a Raman detection probe (37) runs through the transfer cylinder (33), and the Raman detection probe (37) is electrically connected to a spectral fingerprint recognition and display (38) through a signal transmission line; the top of the transfer cylinder (33) is provided with an air purification mechanism (39); The connecting mechanism (35) includes an inclined tube (351) whose bottom is connected to the transfer cylinder (33), and an installation tube (352) connected to the top of the inclined tube (351). The installation tube (352) is provided with a switch closing mechanism (5), and the installation tube (352) passes through one side of the support housing (2). One end of the air blowing tube (36) is located inside the installation tube (352). A pressure sensor is also provided inside the inclined tube (351). The switch closing mechanism (5) includes a closing shell (51) connected to one end of the mounting tube (352), and the closing shell (51) is connected to the inclined tube (351); the closing shell (51) is provided with a closing block (52) inside, and a rubber pad (521) is provided on the outside of the closing block (52). The closing block (52) is connected to the inner wall of the closing shell (51) through the rubber pad (521) provided on the outside; the top of the closing block (52) is provided with a threaded hole, and a lifting screw (53) is threadedly connected to the threaded hole. The top of the lifting screw (53) penetrates the top of the closing shell (51), and the top of the closing shell (51) is provided with a driving component (54) for driving the lifting screw (53); The drive unit (54) includes a micro motor (541) mounted on the top of the closed shell (51), and a first rotating gear (542) is fixedly connected to the output end of the micro motor (541). A second rotating gear (543) is meshed with the outer side of the first rotating gear (542), and the second rotating gear (543) is fixedly sleeved on the top of the lifting screw (53). The tube outlet mechanism (4) includes a support frame (41) located on the top of the testing workbench (1), a placement shell (42) is installed on the support frame (41), and a closed cover plate (43) is provided on the top of the placement shell (42); multiple air blowing tubes (36) are stored inside the placement shell (42), and a first outlet is provided at the bottom of the placement shell (42), and an outlet plate (44) is slidably connected to the bottom of the first outlet. A second outlet is provided on the outlet plate (44) communicating with the first outlet. A discharge plate (45) is slidably connected to the bottom of the outlet plate (44), and an opening is provided on the discharge plate (45). A pusher (46) for driving the outlet plate (44) is provided on the support frame (41).

2. The COVID-19 SARS-CoV-2 Raman-enhanced spectral fingerprint detection device according to claim 1, characterized in that: The filtration mechanism (34) includes a filter (341) installed inside the transfer cylinder (33), and the filter (341) is used to filter the gas inside the transfer cylinder (33).

3. The COVID-19 SARS-CoV-2 Raman-enhanced spectral fingerprint detection device according to claim 1, characterized in that: The air purification mechanism (39) includes an air purifier (391) installed inside the support housing (2), and a positioning tube (392) is installed on the air purifier (391). The air purifier (391) is connected to the top of the transfer cylinder (33) through the positioning tube (392).

4. The COVID-19 SARS-CoV-2 Raman-enhanced spectral fingerprint detection device according to claim 1, characterized in that: The bottom of the support frame (41) is equipped with a receiving plate (411) for receiving the falling air pipe (36), and one end of the receiving plate (411) is provided with a limiting protrusion.

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