Systems, devices, and methods for viral monitoring in effluent

By using a graphene-based field-effect transistor biosensor, the high cost and time-consuming nature of existing wastewater monitoring methods have been solved, enabling low-cost and continuous viral load monitoring, supporting rapid identification of infection trends, and suitable for public health management during the COVID-19 pandemic.

CN116724227BActive Publication Date: 2026-06-19莫顿 M 莫瓦
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
莫顿 M 莫瓦
Filing Date
2021-09-27
Publication Date
2026-06-19

AI Technical Summary

Technical Problem

Existing wastewater monitoring methods are expensive, time-consuming, and require professional personnel, making it difficult to achieve rapid and continuous monitoring of viral load, especially during the COVID-19 pandemic, and unable to provide timely and accurate data support for infection trends.

Method used

Employing a graphene-based field-effect transistor biosensor, the device detects viruses in effluent through a fluid channel, utilizes a capture protein to bind the virus, monitors changes in electrical conductivity in real time, and automatically transmits the monitoring results. The device requires no sampling or manual intervention.

Benefits of technology

It enables low-cost, continuous, and automated virus monitoring, which can promptly identify potential infection hotspots and support rapid response to public health policies.

✦ Generated by Eureka AI based on patent content.

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Abstract

This disclosure relates to a system for monitoring viruses in effluent, the system comprising: a biosensor including: a graphene-based field-effect transistor having a capture protein coupled thereto, the capture protein being configured to bind a virus; and a fluid channel disposed above the graphene-based field-effect transistor such that fluid of the effluent flows through the graphene-based field-effect transistor; and a processing circuit system configured to: apply a gate voltage to the graphene-based field-effect transistor; measure a conductance across the graphene-based field-effect transistor, the conductance reflecting the amount of virus bound to the capture protein; compare the measured conductance with a threshold conductance; and transmit information indicating the presence of the virus in the effluent to a computing device and when the comparison indicates that the measured conductance meets the threshold conductance. In some embodiments, the capture protein may be a SARS-CoV-2 spike antibody.
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