Polytetrafluoroethylene barrier films, applications and methods of making

CN116850343BActive Publication Date: 2026-07-07SHENZHEN LANDO BIOMATERIALS
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
SHENZHEN LANDO BIOMATERIALS
Filing Date
2023-06-26
Publication Date
2026-07-07

AI Technical Summary

Technical Problem

In bone augmentation surgery, the amount of new bone cannot reach the expected level due to the low surface energy of the existing non-absorbable barrier membrane, poor tissue affinity, and difficulty for osteoblasts to adhere and grow.

Method used

A polytetrafluoroethylene barrier membrane is used, with polar groups on the membrane surface. It combines hydrophilic bioactive molecules such as collagen, chitosan or silk fibroin with the bioactive layer. Through plasma treatment and covalent bonding with cross-linking agents, the binding stability between the membrane and the bioactive layer and the adhesion of osteoblasts are improved.

Benefits of technology

It significantly increased the amount of new bone in bone augmentation surgery, enhanced the membrane's ability to maintain space, and improved the growth of osteoblasts.

✦ Generated by Eureka AI based on patent content.

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Abstract

The application provides a polytetrafluoroethylene barrier film and its application and preparation method, and belongs to the technical field of biomedical materials. The polytetrafluoroethylene barrier film comprises a film body and a bioactive layer on the surface of the film body; wherein the material of the film body comprises polytetrafluoroethylene, and the outer surface of the film body has a polar group; the material of the bioactive layer comprises a hydrophilic bioactive molecule. In the polytetrafluoroethylene barrier film provided by the application, the polar group on the outer surface of the polytetrafluoroethylene film body interacts with and effectively combines with the hydrophilic bioactive molecule, the combination stability between the film body and the bioactive layer is improved, the adhesion and growth of osteoblasts can be realized, and then the new bone mass during the bone augmentation surgery using the polytetrafluoroethylene barrier film is improved. In addition, the hydrophilic bioactive molecule can also endow the polytetrafluoroethylene barrier film with multifunctionality due to its characteristics.
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