A gas phase aminolysis control system and control method

Abstract

The application discloses a kind of gas phase ammonolysis control system and control method, it is related to ammonolysis control technical field, including parameter setting module, controller, temperature regulator and pressure regulator;Controller is used to compare and analyze the internal temperature of reaction kettle with preset parameter, to drive temperature regulator to adjust the internal temperature of reaction kettle;When receiving heating signal, temperature regulator is used to carry out temperature regulation index analysis in combination with external environment temperature and the internal temperature of reaction kettle, and the valve opening of heat conducting oil valve is determined according to temperature regulation index auxiliary;Effectively improve temperature control precision and smoothness, reduce heat energy loss and reduce production cost;Pressure regulator is used to carry out pressure regulation index analysis in combination with the internal pressure of reaction kettle and ammonolysis correlation parameter, to facilitate analysis to obtain the best intake flow of reaction kettle;Make ammonia gas can enter into reaction kettle with suitable speed, effectively improve pressure control precision and smoothness, improve ammonolysis reaction safety.

Description

Technical Field

[0001] This invention relates to the field of ammonia hydrolysis control technology, specifically a gas-phase ammonia hydrolysis control system and control method. Background Technology

[0002] Oligonucleotide chemical synthesis began in the late 1940s. By the 1960s and 1970s, the methods for oligonucleotide chemical synthesis had been continuously improved, gradually forming the solid-phase phosphoramidite method that is widely used today and has achieved automated synthesis. The synthesized oligonucleotides need to be cleaved under the alkaline conditions of ammonia to remove the protecting groups on the bases and to cleave the synthesized oligonucleotides from the solid support to obtain the synthesized oligonucleotides.

[0003] Current ammonolysis methods mainly include ammonia water ammonolysis, electrically heated ammonia gas-phase ammonolysis, and microwave heating ammonolysis, among others. Ammonia water ammonolysis has a low throughput, and its efficiency is affected by low ammonia concentration, resulting in unstable efficiency. Microwave heating methods suffer from uncontrollable temperature and unstable ammonolysis quality. Electrically heated gas-phase ammonolysis exhibits poor temperature stability, with temperature fluctuations reaching approximately 10°C. Existing commonly used ammonolysis methods, such as ammonia water ammonolysis, generally require 8-12 hours of ammonolysis, and the ammonia concentration can deviate significantly. Electrically heated gas-phase ammonolysis suffers from large temperature fluctuations and requires approximately 2-2.5 hours of ammonolysis time. Based on these shortcomings, this invention proposes a gas-phase ammonolysis control system and method. Summary of the Invention

[0004] The present invention aims to solve at least one of the technical problems existing in the prior art. To this end, the present invention proposes a gas-phase ammonium hydrolysis control system and control method.

[0005] To achieve the above objectives, an embodiment of the first aspect of the present invention provides a gas phase ammonium hydrolysis control system, applied to a gas phase ammonium hydrolysis device, comprising a parameter setting module, a temperature acquisition module, a temperature regulator, a pressure acquisition module, and a pressure regulator;

[0006] The gas phase ammonolysis device includes an ammonia cylinder, a reaction vessel, and a heat transfer oil valve; the ammonia cylinder and the reaction vessel are connected by an inlet pipe, and the inlet pipe is equipped with an inlet valve;

[0007] The parameter setting module is used by the user to set preset parameters; the preset parameters include reaction temperature range (W2-W3), temperature setpoint, pressure setpoint, temperature correction factor, and pressure correction factor;

[0008] The temperature acquisition module is used to acquire the internal temperature of the reactor in real time and transmit the internal temperature of the reactor to the controller; the controller is used to compare and analyze the internal temperature of the reactor with preset parameters, thereby driving the temperature regulator to adjust the internal temperature of the reactor.

[0009] When a heating signal is received, the temperature regulator is used to perform temperature regulation index WZ analysis by combining the external ambient temperature and the internal temperature TN of the reactor, and to assist in determining the valve opening of the heat transfer oil valve based on the temperature regulation index WZ; when the internal temperature of the reactor reaches the set temperature TS, the temperature regulator drives the heat transfer oil valve to close and generates a temperature compliance signal to the controller.

[0010] In response to the temperature reaching the target signal, the controller opens the ammonia cylinder and the inlet valve; the pressure acquisition module collects the internal pressure of the reactor in real time and transmits the internal pressure of the reactor to the controller;

[0011] When the internal pressure of the reactor is lower than the pressure set value, a pressurization signal is generated; the pressure regulator is used to control the valve opening of the inlet valve to regulate the internal pressure of the reactor.

[0012] The pressure regulator is used to perform pressure regulation index YZ analysis by combining the internal pressure of the reactor and the ammonia decomposition correlation parameters, so as to analyze and determine the optimal gas inlet flow rate Lt of the reactor.

[0013] The pressure regulator is used to adaptively adjust the valve opening of the inlet valve according to the optimal inlet flow rate Lt; when the internal pressure of the reactor reaches the pressure set value MS or is within the pressure correction range, the pressure regulator controls the inlet valve to close and generates a pressure compliance signal to the controller.

[0014] Furthermore, the specific analysis process of the temperature regulator is as follows:

[0015] Obtain the external ambient temperature and label it as TW; compare the internal temperature TN of the reactor with the reaction temperature range (W2-W3); if TN is lower than the reaction temperature range (W2-W3), the temperature regulation index WZ is calculated as follows: WZ=b1×(W2-TN)×W3 / W2+b2×(TS-TN)×W2 / TW; where b1 and b2 are preset coefficient factors;

[0016] If TN is within the reaction temperature range (W2-W3), the temperature regulation index WZ can be calculated using the formula WZ=b2×(TS-TN)×W2 / TW;

[0017] Set valve opening thresholds for several heat transfer oil valves, each valve opening threshold corresponding to a preset temperature regulation index range; match the temperature regulation index WZ with all preset temperature regulation index ranges to obtain the corresponding valve opening threshold and mark it as Fm;

[0018] The temperature regulator is used to drive and control the opening degree of the heat transfer oil valve to Fm, thereby heating the inside of the reactor.

[0019] Furthermore, the specific analysis process of the controller is as follows:

[0020] The internal temperature of the reactor is acquired and marked as TN; the temperature setpoint is marked as TS; the temperature correction factor is marked as Xs; when the internal temperature TN is lower than the reaction temperature range (W2-W3) or (TS-TN) / TS≥Xs, a heating signal is generated;

[0021] After receiving the heating signal, the controller drives the temperature regulator to heat the inside of the reactor until the internal temperature of the reactor reaches the set temperature value.

[0022] Furthermore, the specific analysis process of the pressure regulator is as follows:

[0023] Obtain the internal pressure of the reactor and label it as M1; label the pressure setpoint as MS; label the pressure correction coefficient as Mx; obtain the ammonia decomposition related parameters of the reactor, and label the ammonia inlet concentration, liquid level, water temperature, and humidity as M2, M3, M4, and M5 respectively; calculate the pressure regulation index YZ using the formula YZ=f×[(MS-M1)+(M5×b3)] / (M2×b4+M3×b5+M4×b6), where b3, b4, b5, and b6 are preset coefficient factors; f is the preset equilibrium coefficient;

[0024] The optimal inlet flow rate of the reactor is determined to be Lt based on the pressure regulation index YZ; specifically, the database contains a pre-stored mapping table between the pressure regulation index range and the inlet flow rate threshold.

[0025] Based on the mapping table, determine the intake flow rate threshold corresponding to the pressure regulation index YZ and mark it as the optimal intake flow rate Lt.

[0026] Furthermore, it also includes a parameter acquisition module; the parameter acquisition module is used to acquire the ammonia decomposition related parameters of the reactor and transmit the ammonia decomposition related parameters to the controller; the ammonia decomposition related parameters include ammonia gas inlet concentration, liquid level, water temperature and humidity; wherein, the pressure correction range is MS×(1-Mx)—MS×(1+Mx).

[0027] Furthermore, a heat transfer oil valve is connected to the lower end of the reactor, which is used to conduct heat to the inside of the reactor; a pressure gauge and a PT100 thermocouple are installed inside the reactor; the pressure gauge is used to detect the internal pressure of the reactor in real time, and the PT100 thermocouple is used to detect the internal temperature of the reactor in real time, and the detected temperature information is displayed in real time through a temperature display table.

[0028] Furthermore, during the use of the gas phase ammonolysis device, the required ammonia pressure and temperature inside the reactor are first set; the reactor is heated to the set temperature through the heat transfer oil valve, and then water is added into the reactor; the sample plate to be ammonolyzed is placed on the sample rack, and the sample rack is placed into the reactor.

[0029] Then, open the ammonia cylinder and the inlet valve to introduce ammonia into the reactor. Once the pressure inside the reactor reaches the set pressure, close the inlet valve. Then, keep the reactor warm for 1 hour to complete the sample ammonolysis operation. Finally, open the exhaust valve to release excess ammonia, remove the ammonolyzed sample, and the sample ammonolysis is complete.

[0030] Furthermore, a method for controlling gas-phase ammonolysis includes the following steps:

[0031] Step 1: Users set preset parameters in the system's HMI interface through the parameter setting module;

[0032] Step 2: The internal temperature of the reactor is adjusted by controlling the valve opening of the heat transfer oil valve through a temperature regulator; specifically, the temperature regulator is used to perform temperature regulation index WZ analysis by combining the external ambient temperature and the internal temperature TN of the reactor, and to determine the valve opening of the heat transfer oil valve based on the temperature regulation index WZ.

[0033] Step 3: When the internal temperature of the reactor reaches the set temperature TS, the temperature regulator drives the heat transfer oil valve to close and generates a temperature compliance signal to the controller; the controller is used to open the ammonia cylinder and the inlet valve to introduce ammonia into the reactor.

[0034] Step 4: Adjust the internal pressure of the reactor by controlling the opening of the inlet valve through the pressure regulator; when the internal pressure of the reactor reaches the pressure set value MS or is within the pressure correction range, the pressure regulator controls the inlet valve to close.

[0035] Compared with the prior art, the beneficial effects of the present invention are:

[0036] 1. The parameter setting module of this invention is used by the user to set preset parameters; the temperature acquisition module is used to acquire the internal temperature of the reactor in real time and transmit the internal temperature of the reactor to the controller; the controller is used to compare and analyze the internal temperature of the reactor with the preset parameters, thereby driving the temperature regulator to adjust the internal temperature of the reactor; when a heating signal is received, the temperature regulator is used to perform temperature regulation index WZ analysis by combining the external ambient temperature and the internal temperature TN of the reactor, and to assist in determining the valve opening of the heat transfer oil valve based on the temperature regulation index WZ; effectively improving the temperature control accuracy and stability, reducing heat loss and lowering production costs;

[0037] 2. The pressure acquisition module of this invention acquires the internal pressure of the reactor in real time; when the internal pressure of the reactor is lower than the pressure set value, a pressurization signal is generated; the pressure regulator is used to perform pressure regulation index YZ analysis by combining the internal pressure of the reactor and the ammonia decomposition correlation parameters, so as to analyze and obtain the optimal gas inlet flow rate Lt of the reactor; the pressure regulator is used to adaptively adjust the valve opening of the gas inlet valve according to the optimal gas inlet flow rate Lt, so that ammonia can enter the reactor at a suitable speed, effectively improving the pressure control accuracy and stability, and improving the safety of the ammonia decomposition reaction. Attached Figure Description

[0038] To more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0039] Figure 1 This is a system block diagram of a gas-phase ammonium hydrolysis control system according to the present invention.

[0040] Figure 2 This is a schematic diagram illustrating the principle of a gas-phase ammonolysis control method according to the present invention. Detailed Implementation

[0041] The technical solution of the present invention will be clearly and completely described below with reference to the embodiments. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0042] like Figures 1 to 2 As shown, a gas phase ammonium hydrolysis control system is applied to a gas phase ammonium hydrolysis device, including a parameter setting module, a temperature acquisition module, a controller, a temperature regulator, a pressure acquisition module, a parameter acquisition module, a pressure regulator, and a database.

[0043] The gas phase ammonolysis unit includes an ammonia cylinder, a reactor, and a heat transfer oil valve; the ammonia cylinder and the reactor are connected by an inlet pipe, and an inlet valve is installed on the inlet pipe;

[0044] A heat transfer oil valve is connected to the lower end of the reactor, which is used to conduct heat to the inside of the reactor. A pressure gauge and a PT100 thermocouple are installed inside the reactor. The pressure gauge is used to detect the internal pressure of the reactor in real time, and the PT100 thermocouple is used to detect the internal temperature of the reactor in real time. The detected temperature information is displayed in real time through a temperature display table.

[0045] The parameter setting module is used by the user to set preset parameters in the system's HMI interface; the preset parameters include reaction temperature range (W2-W3), temperature setpoint, pressure setpoint, temperature correction factor, and pressure correction factor; in this embodiment, W2-W3 is 45℃~100℃; the temperature setpoint is within the range of W2-W3;

[0046] The temperature acquisition module is connected to the temperature display meter to read the temperature information displayed on the temperature display meter and transmit the read temperature information to the controller; the controller is used to obtain the preset parameters set by the user in the parameter setting module, and compare and analyze the preset parameters with the temperature information read by the temperature acquisition module, thereby driving the control temperature regulator to adjust the internal temperature of the reactor.

[0047] The specific analysis process of the controller is as follows:

[0048] Obtain the internal temperature of the reactor and label it TN; label the temperature setpoint as TS; label the temperature correction factor as Xs; for example, Xs is set to 1.5%;

[0049] When the internal temperature TN is lower than the reaction temperature range (W2-W3) or (TS-TN) / TS≥Xs, a heating signal is generated; after receiving the heating signal, the controller drives the temperature regulator to heat the inside of the reactor until the internal temperature of the reactor reaches the set temperature value.

[0050] The temperature controller is used to control the valve opening of the heat transfer oil valve to regulate the internal temperature of the reactor. When a heating signal is received, the temperature controller performs a temperature regulation index (WZ) analysis by combining the external ambient temperature and the internal temperature (TN) of the reactor, and determines the valve opening of the heat transfer oil valve based on the temperature regulation index (WZ). The specific analysis process is as follows:

[0051] Obtain the external ambient temperature and label it as TW; compare the internal temperature TN of the reactor with the reaction temperature range (W2-W3); if TN is lower than the reaction temperature range (W2-W3), the temperature regulation index WZ is calculated as follows: WZ=b1×(W2-TN)×W3 / W2+b2×(TS-TN)×W2 / TW; where b1 and b2 are preset coefficient factors;

[0052] If TN is within the reaction temperature range (W2-W3), the temperature regulation index WZ can be calculated using the formula WZ=b2×(TS-TN)×W2 / TW;

[0053] Set valve opening thresholds for several heat transfer oil valves, each valve opening threshold corresponding to a preset temperature regulation index range; the larger the temperature regulation index, the larger the corresponding valve opening threshold; match the temperature regulation index WZ with all preset temperature regulation index ranges to obtain the corresponding valve opening threshold and mark it as Fm;

[0054] The temperature regulator is used to drive and control the valve opening of the heat transfer oil valve to reach Fm, thereby heating the inside of the reactor, effectively improving the accuracy and stability of temperature control, reducing heat loss and lowering production costs;

[0055] When the internal temperature of the reactor reaches the set temperature TS, the temperature regulator drives the heat transfer oil valve to close and generates a temperature compliance signal to the controller.

[0056] Upon receiving a temperature compliance signal, the controller opens the ammonia cylinder and the inlet valve, introducing ammonia into the reactor; the pressure acquisition module reads the pressure information displayed on the pressure gauge and transmits the read pressure information to the controller.

[0057] The parameter acquisition module is used to collect the ammonia hydrolysis-related parameters of the reactor and transmit these parameters to the controller. The ammonia hydrolysis-related parameters include ammonia gas inlet concentration, liquid level, water temperature, humidity, etc.

[0058] The controller compares and analyzes the received pressure information with preset parameters, thereby driving the control pressure regulator to adjust the internal pressure of the reactor; when the internal pressure of the reactor is lower than the pressure set value, a pressurization signal is generated; the pressure regulator controls the valve opening of the air inlet valve to adjust the internal pressure of the reactor.

[0059] When a pressurization signal is received, the pressure regulator performs pressure regulation index YZ analysis by combining the internal pressure of the reactor and ammonolysis correlation parameters, in order to determine the optimal inlet flow rate of the reactor; the specific analysis process is as follows:

[0060] Obtain the internal pressure of the reactor and label it M1; label the pressure setpoint as MS; label the pressure correction factor as Mx;

[0061] The ammonia decomposition correlation parameters of the reactor are obtained, and the ammonia gas inlet concentration, liquid level, water temperature, and humidity are labeled as M2, M3, M4, and M5 respectively. The pressure regulation index YZ is calculated using the formula YZ=f×[(MS-M1)+(M5×b3)] / (M2×b4+M3×b5+M4×b6), where b3, b4, b5, and b6 are preset coefficient factors; f is a preset equilibrium coefficient.

[0062] The optimal inlet flow rate of the reactor is determined to be Lt based on the pressure regulation index YZ; specifically:

[0063] The database contains a pre-stored mapping table between the pressure regulation index range and the intake flow rate threshold;

[0064] Based on the mapping table, determine the intake flow rate threshold corresponding to the pressure regulation index YZ and mark it as the optimal intake flow rate Lt;

[0065] The pressure regulator is used to adaptively adjust the valve opening of the inlet valve according to the optimal inlet flow rate Lt, so that ammonia gas can enter the reactor at a suitable rate, effectively improving the accuracy and stability of pressure control and enhancing the safety of the ammonium hydrolysis reaction.

[0066] When the internal pressure of the reactor reaches the pressure setpoint MS or is within the pressure correction range, the pressure regulator controls the inlet valve to close and generates a pressure compliance signal to the controller; wherein, the pressure correction range is MS×(1-Mx)-MS×(1+Mx); for example, Mx is 2%;

[0067] During the operation of the gas phase ammonium hydrolysis apparatus, first set the required ammonia pressure and temperature inside the reactor; heat the reactor to the set temperature through the heat transfer oil valve, then add clean water into the reactor; place the sample plate to be ammonized on the sample rack, and then place the sample rack into the reactor;

[0068] Then, open the ammonia cylinder and the inlet valve to introduce ammonia into the reactor. Once the pressure inside the reactor reaches the set pressure, close the inlet valve. Then, maintain the temperature for 1 hour to complete the sample ammonolysis operation. Finally, open the exhaust valve to release excess ammonia, remove the ammonolyzed sample, and the sample ammonolysis is complete. Multiple sample plates can be placed on the sample rack at the same time, allowing for simultaneous ammonolysis of multiple sample plates. This convenient operation greatly improves the speed and quality of subsequent purification of synthesized oligonucleotide products.

[0069] A gas-phase ammonolysis control method, applied to the aforementioned gas-phase ammonolysis control system, includes:

[0070] Step 1: Users set preset parameters in the system's HMI interface through the parameter setting module;

[0071] Step 2: The internal temperature of the reactor is adjusted by controlling the valve opening of the heat transfer oil valve through a temperature regulator; specifically, the temperature regulator is used to perform temperature regulation index WZ analysis by combining the external ambient temperature and the internal temperature TN of the reactor, and the valve opening of the heat transfer oil valve is determined based on the temperature regulation index WZ.

[0072] Step 3: When the internal temperature of the reactor reaches the set temperature TS, the temperature regulator drives the control of the heat transfer oil valve to close and generates a temperature compliance signal to the controller; the controller is used to open the ammonia cylinder and the inlet valve to introduce ammonia into the reactor.

[0073] Step 4: Adjust the internal pressure of the reactor by controlling the opening of the inlet valve through the pressure regulator; when the internal pressure of the reactor reaches the pressure set value MS or is within the pressure correction range, the pressure regulator controls the inlet valve to close.

[0074] The above formulas are all numerical calculations after removing dimensions. The formulas are obtained by software simulation based on a large amount of data and are closest to the real situation. The preset parameters and preset thresholds in the formulas are set by those skilled in the art according to the actual situation or obtained by simulation based on a large amount of data.

[0075] In the description of this specification, references to terms such as "an embodiment," "example," "specific example," etc., indicate that a specific feature, structure, material, or characteristic described in connection with that embodiment or example is included in at least one embodiment or example of the invention. In this specification, illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples.

[0076] The preferred embodiments of the present invention disclosed above are merely illustrative of the invention. These preferred embodiments do not exhaustively describe all details, nor do they limit the invention to any specific implementation. Clearly, many modifications and variations can be made based on the content of this specification. This specification selects and specifically describes these embodiments to better explain the principles and practical applications of the invention, thereby enabling those skilled in the art to better understand and utilize the invention. The invention is limited only by the claims and their full scope and equivalents.

Claims

1. A gas-phase ammonolysis control system, applied to a gas-phase ammonolysis device, characterized in that, It includes a parameter setting module, a temperature acquisition module, a temperature regulator, a pressure acquisition module, and a pressure regulator; The gas phase ammonolysis device includes an ammonia cylinder, a reaction vessel, and a heat transfer oil valve; the ammonia cylinder and the reaction vessel are connected by an inlet pipe, and the inlet pipe is equipped with an inlet valve; The parameter setting module is used by the user to set preset parameters; the preset parameters include reaction temperature range W2-W3, temperature set value, pressure set value, temperature correction coefficient, and pressure correction coefficient; The temperature acquisition module is used to acquire the internal temperature of the reactor in real time and transmit the internal temperature of the reactor to the controller; the controller is used to compare and analyze the internal temperature of the reactor with preset parameters, thereby driving the temperature regulator to adjust the internal temperature of the reactor. The specific analysis process of the controller is as follows: The internal temperature of the reactor is acquired and marked as TN; the temperature setpoint is marked as TS; the temperature correction factor is marked as Xs; when the internal temperature TN is lower than the reaction temperature range W2-W3 or (TS-TN) / TS≥Xs, a heating signal is generated; After receiving the heating signal, the controller drives the temperature regulator to heat the inside of the reactor until the internal temperature of the reactor reaches the set temperature value. When a heating signal is received, the temperature regulator is used to perform temperature regulation index WZ analysis by combining the external ambient temperature and the internal temperature TN of the reactor. The specific analysis process is as follows: Obtain the external ambient temperature and label it as TW; compare the internal temperature TN of the reactor with the reaction temperature range W2-W3; if TN is lower than the reaction temperature range W2-W3, the temperature regulation index WZ is calculated as follows: WZ=b1×(W2-TN)×W3 / W2+b2×(TS-TN)×W2 / TW; where b1 and b2 are preset coefficient factors; If TN is within the reaction temperature range W2-W3, the temperature regulation index WZ can be calculated using the formula WZ=b2×(TS-TN)×W2 / TW. Set valve opening thresholds for several heat transfer oil valves, each valve opening threshold corresponding to a preset temperature regulation index range; match the temperature regulation index WZ with all preset temperature regulation index ranges to obtain the corresponding valve opening threshold and mark it as Fm; The temperature regulator is used to drive and control the valve opening of the heat transfer oil valve to reach Fm, thereby heating the inside of the reactor. When the internal temperature of the reactor reaches the set temperature TS, the temperature regulator drives the heat transfer oil valve to close and generates a temperature compliance signal to the controller. In response to the temperature reaching the target signal, the controller opens the ammonia cylinder and the inlet valve; the pressure acquisition module collects the internal pressure of the reactor in real time and transmits the internal pressure of the reactor to the controller; When the internal pressure of the reactor is lower than the pressure set value, a pressurization signal is generated; the pressure regulator is used to control the valve opening of the inlet valve to regulate the internal pressure of the reactor. The pressure regulator is used to perform pressure regulation index YZ analysis by combining the internal pressure of the reactor and the ammonia decomposition correlation parameters, so as to analyze and determine the optimal gas inlet flow rate Lt of the reactor. The specific analysis process of the pressure regulator is as follows: Obtain the internal pressure of the reactor and label it as M1; label the pressure setpoint as MS; label the pressure correction coefficient as Mx; obtain the ammonia decomposition related parameters of the reactor, and label the ammonia inlet concentration, liquid level, water temperature, and humidity as M2, M3, M4, and M5 respectively; calculate the pressure regulation index YZ using the formula YZ=ƒ×[(MS-M1)+(M5×b3)] / (M2×b4+M3×b5+M4×b6), where b3, b4, b5, and b6 are all preset coefficient factors; ƒ is the preset balance coefficient; The optimal inlet flow rate of the reactor is determined to be Lt based on the pressure regulation index YZ; specifically, the database contains a pre-stored mapping table between the pressure regulation index range and the inlet flow rate threshold. Based on the mapping table, determine the intake flow rate threshold corresponding to the pressure regulation index YZ and mark it as the optimal intake flow rate Lt; The pressure regulator is used to adaptively adjust the valve opening of the inlet valve according to the optimal inlet flow rate Lt; when the internal pressure of the reactor reaches the pressure set value MS or is within the pressure correction range, the pressure regulator controls the inlet valve to close and generates a pressure compliance signal to the controller.

2. The gas-phase ammonia electrolysis control system according to claim 1, characterized in that, It also includes a parameter acquisition module; the parameter acquisition module is used to acquire the ammonia decomposition related parameters of the reactor and transmit the ammonia decomposition related parameters to the controller; the ammonia decomposition related parameters include ammonia gas inlet concentration, liquid level, water temperature and humidity; wherein, the pressure correction range is MS×(1-Mx)—MS×(1+Mx).

3. The gas-phase ammonia hydrolysis control system according to claim 1, characterized in that, The lower end of the reactor is connected to a heat transfer oil valve, which is used to conduct heat to the inside of the reactor. The reactor is equipped with a pressure gauge and a PT100 thermocouple. The pressure gauge is used to detect the internal pressure of the reactor in real time, and the PT100 thermocouple is used to detect the internal temperature of the reactor in real time. The detected temperature information is displayed in real time through a temperature display table.

4. A gas-phase ammonia hydrolysis control system according to claim 3, characterized in that, During the use of the gas phase ammonium hydrolysis device, the required ammonia pressure and temperature in the reactor are first set; the reactor is heated to the set temperature through the heat transfer oil valve, and then water is added to the reactor; the sample plate to be ammonium hydrolyzed is placed on the sample rack, and the sample rack is placed into the reactor. Then open the ammonia cylinder and the inlet valve to introduce ammonia into the reactor. Once the pressure inside the reactor reaches the set pressure, close the inlet valve. Then keep it warm for 1 hour to complete the ammonolysis of the sample; finally, open the exhaust valve to release excess ammonia gas, take out the ammonolyzed sample, and the ammonolysis of the sample is complete.

5. A gas-phase ammonolysis control method, applied to a gas-phase ammonolysis control system as described in any one of claims 1-4, characterized in that, Includes the following steps: Step 1: Users set preset parameters in the system's HMI interface through the parameter setting module; Step 2: The internal temperature of the reactor is adjusted by controlling the valve opening of the heat transfer oil valve through a temperature regulator; specifically, the temperature regulator is used to perform temperature regulation index WZ analysis by combining the external ambient temperature and the internal temperature TN of the reactor, and to determine the valve opening of the heat transfer oil valve based on the temperature regulation index WZ. Step 3: When the internal temperature of the reactor reaches the set temperature TS, the temperature regulator drives the heat transfer oil valve to close and generates a temperature compliance signal to the controller; the controller is used to open the ammonia cylinder and the inlet valve to introduce ammonia into the reactor. Step 4: Adjust the internal pressure of the reactor by controlling the opening of the inlet valve through the pressure regulator; when the internal pressure of the reactor reaches the pressure set value MS or is within the pressure correction range, the pressure regulator controls the inlet valve to close.

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