A method for preparing a phosphorus supplement injection

By adding stabilizers and antioxidants to the preparation method, the stability and irritation problems of toluidine sodium injection have been solved, expanding its application range and improving its efficacy, thus filling a gap in the domestic market.

CN117159460BActive Publication Date: 2026-06-19CHINA AGRI UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
CHINA AGRI UNIV
Filing Date
2023-09-19
Publication Date
2026-06-19

AI Technical Summary

Technical Problem

The application scope of existing technologies for tortidine sodium injection is limited, and there are issues with stability and irritation to animals. There is no related technology research and development in China.

Method used

A method for preparing phosphorus supplement injections, including the addition of stabilizers, antioxidants, preservatives, and acid-base regulators, followed by stirring, filtration, and sterilization steps, yields a toluidine sodium phosphate injection with reduced stability and irritation.

Benefits of technology

It expands the application range of sodium tropane, improves the stability of the injection under harsh conditions, reduces irritation to animals, and enhances efficacy and preservation properties.

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Abstract

This invention relates to a method for preparing a phosphorus supplement injection solution. The method includes the following steps: weighing purified water and an organic solvent, adding a stabilizer and a phosphorus supplement, stirring until completely dissolved, then adding a preservative and an antioxidant, stirring until homogeneous, adjusting the pH with an acid-base adjuster, bringing the purified water to a fixed volume, filtering, and sterilizing to obtain the phosphorus supplement injection solution. This invention fills a gap in the domestic market for phosphorus supplement injection solutions, exhibits good process reproducibility, and has broad application prospects.
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