A guide wire catheter device with drug administration function

Abstract

The application provides a guide wire and catheter device with a drug delivery function, and relates to the technical field of medical supplies. The guide wire and catheter device with the drug delivery function comprises a drug delivery guide wire and a catheter. The front end of the drug delivery guide wire is provided with a capsule, the capsule is filled with a medicament, and the capsule partially protrudes from the surface of the drug delivery guide wire. The catheter is provided with a penetration channel and a driving structure. The penetration channel is used for penetration of the drug delivery guide wire. The catheter is provided with a pressing member. The driving structure is used for driving the pressing member so that the pressing member breaks the capsule. The device can accurately control the amount of medicament reaching a lesion area while achieving medicament delivery.

Description

Technical Field

[0001] This application relates to the field of medical device technology, and in particular to a guidewire catheter device with drug delivery function. Background Technology

[0002] When treating internal cavities such as the intestines, it is sometimes necessary to deliver medication directly to the affected area so that the medication can be quickly absorbed, thereby improving the treatment effect. In clinical practice, a drug delivery catheter is typically used to perform this procedure.

[0003] Before administering medication, a delivery catheter is inserted into the cavity, with one end of the catheter inserted into the patient's body moved to the lesion area. The other end of the catheter is external and connected to a delivery pump. During medication administration, the delivery pump is activated, using it to deliver the medication via the delivery catheter to the lesion area.

[0004] Some lesions are located deep within the body, requiring longer drug delivery catheters (over 50cm). The length of the catheter determines the length of the drug flow path. If the catheter is too long, some drug will remain on the catheter wall during delivery, resulting in a significantly smaller amount reaching the lesion area than the pumped out. Healthcare professionals often rely on experience to determine the total amount of medication to deliver, but this is inaccurate: too much medication leads to waste and increases the patient's metabolic burden; too little medication affects treatment effectiveness. Summary of the Invention

[0005] The purpose of this application is to overcome the deficiencies of the prior art and provide a guidewire catheter device with drug delivery function to solve the problems in the prior art.

[0006] To address the aforementioned issues, this application provides a guidewire and catheter device with drug delivery function, comprising a drug delivery guidewire and a catheter. The front end of the drug delivery guidewire is provided with a capsule, which is filled with a drug, wherein the capsule portion protrudes from the surface of the drug delivery guidewire. The catheter is provided with an insertion channel and a driving structure; The insertion channel is used for the insertion of the drug delivery guidewire; The conduit is provided with a squeezing member, wherein the driving structure is used to drive the squeezing member so that the squeezing member ruptures the capsule.

[0007] In one possible implementation, the drive structure includes an airbag disposed around the conduit; The catheter includes a first tube section and a second tube section, and the airbag is located between the first tube section and the second tube section, wherein both the first tube section and the second tube section are fixedly connected to the airbag.

[0008] In one possible implementation, the airbag includes a first component and a second component that are sealed together, with an inflation space formed between the first component and the second component; The inner walls of the first component and the second component are disposed opposite to each other, wherein the outer wall of the second component faces the insertion channel; the second component is used to move toward the inside of the insertion channel when the airbag is filled with gas; The extrusion member is fixed to the outer wall of the second component and is located inside the insertion channel.

[0009] In one possible implementation, the elastic modulus of the first component is greater than that of the second component.

[0010] In one possible implementation, an inflation pipe is fixedly provided on the outer wall of the conduit; wherein the inflation pipe is connected to the inflation space, and the inflation pipe is used to inflate the inflation space with gas.

[0011] In one possible implementation, a sensing module is provided inside the insertion channel, and the drug delivery guidewire is provided with a mating part for being sensed by the sensing module. When the sensing module senses the mating part, the drug delivery guidewire is in a preset position relative to the catheter; The portion of the capsule that protrudes beyond the drug delivery guidewire is the extension portion; wherein, when the drug delivery guidewire is located at the preset position, the squeezing member is directly opposite the extension portion.

[0012] In one possible implementation, the sensing module includes a thin-film pressure sensor, and the mating portion includes a protrusion surrounding the outer wall of the drug delivery guidewire; wherein the mating portion is configured to be sensed by the sensing module by squeezing the sensing module.

[0013] In one possible implementation, the capsule is cylindrical, and the extruder includes a concave and arc-shaped extrusion surface for conforming to the outer surface of the capsule; there are multiple extruders arranged in a ring array.

[0014] In one possible implementation, a guidewire is also included for guiding the catheter.

[0015] In one possible implementation, the front end of the drug delivery guidewire is provided with an installation groove, and the capsule is embedded in the installation groove, wherein a portion of the capsule protrudes beyond the installation groove.

[0016] The beneficial effects of this application include: The guidewire-catheter device with drug delivery function proposed in this application includes a drug delivery guidewire and a catheter. A capsule containing a drug is disposed at the tip of the drug delivery guidewire, with the capsule portion protruding from the surface of the guidewire. When the tip of the catheter moves to the lesion area, a driving structure can drive a squeezing element, causing the capsule to rupture. After the capsule ruptures, the drug inside is released, allowing the lesion area to absorb the drug.

[0017] This device not only delivers the medication but also allows for more precise control of the dosage reaching the lesion area. Attached Figure Description

[0018] To more clearly illustrate the technical solutions of the embodiments of this application, the accompanying drawings used in the embodiments will be briefly introduced below. It should be understood that the following drawings only show some embodiments of this application and should not be regarded as a limitation of the scope. For those skilled in the art, other related drawings can be obtained based on these drawings without creative effort.

[0019] Figure 1 A schematic diagram of a drug delivery guidewire is shown; Figure 2 A schematic diagram of a catheter is shown; Figure 3 It shows Figure 2 Cross-sectional view of the tip of the middle conduit; Figure 4 This diagram illustrates the positional relationship between the drug delivery guidewire and the catheter when the guidewire is inserted into the catheter. Figure 5 A connection block diagram of a thin-film pressure sensor, a control module, and a display screen is shown. Figure 6 A schematic diagram of an extruded component is shown.

[0020] Explanation of key component symbols: 10-Drug delivery guidewire; 101-Matching part; 102-Conical part; 20-Catheter; 201-First tubular part; 202-Second tubular part; 21-Insertion channel; 211-Sensing module; 22-Drive structure; 221-First component; 222-Second component; 23-Extrusion piece; 231-Extrusion surface; 24-Inflation pipe; 25-Opening; 30-Capsule; 41-Thin-film pressure sensor; 42-Control module; 43-Display screen. Detailed Implementation

[0021] The embodiments of this application are described in detail below. Examples of these embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals denote the same or similar elements or elements having the same or similar functions throughout. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain this application, and should not be construed as limiting this application.

[0022] In the description of this application, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential", etc., indicating the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings, are only for the convenience of describing this application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this application.

[0023] Example See Figure 1 and Figure 2 In this embodiment, a guidewire catheter device with drug delivery function is proposed, including a drug delivery guidewire 10 and a catheter 20. The front end of the drug delivery guidewire 10 is provided with a capsule 30, which is filled with a drug. The capsule 30 protrudes from the surface of the drug delivery guidewire 10.

[0024] For mounting the capsule 30, the front end of the drug delivery guidewire 10 may be provided with a mounting groove, into which the capsule 30 is embedded, wherein a portion of the capsule 30 protrudes beyond the mounting groove. The capsule 30 and the mounting groove may be connected by an interference fit.

[0025] Capsule 30 may be a soft capsule. Capsule 30 may be made of materials such as gelatin that can be dissolved and absorbed by the intestines. The medication may be in liquid form.

[0026] In this embodiment, the catheter 20 is provided with an insertion channel 21 and a driving structure 22.

[0027] Insertion channel 21 is used to supply the insertion of the drug guide wire 10.

[0028] A squeezing element 23 is provided on the conduit 20. The driving structure 22 is used to drive the squeezing element 23 so that the squeezing element 23 ruptures the capsule 30. When the capsule 30 is ruptured, the medicine inside the capsule 30 will flow out.

[0029] In this embodiment, the drive structure 22 includes an airbag, which is disposed around the conduit 20.

[0030] like Figure 3 As shown, the catheter 20 includes a first tube section 201 and a second tube section 202, with an airbag located between the first tube section 201 and the second tube section 202. Both the first tube section 201 and the second tube section 202 are fixedly connected to the airbag. The first tube section 201 and the second tube section 202 can be fixedly connected to the airbag by means of laser welding or other methods.

[0031] In this embodiment, the airbag includes a first component 221 and a second component 222 that are sealed together, and an inflation space is formed between the first component 221 and the second component 222.

[0032] The first component 221 and the second component 222 are both arranged circumferentially around the conduit 20. Along the length of the conduit 20, the two ends of the first component 221 are correspondingly and sealingly connected to the two ends of the second component 222. Specifically, laser welding can also be used to achieve the connection between the first component 221 and the second component 222.

[0033] Reference Figure 3 The inner walls of the first component 221 and the second component 222 are arranged opposite to each other, and the inflation space is enclosed in the inner walls of the first component 221 and the second component 222.

[0034] The outer wall of the second component 222 faces the insertion channel 21, and the second component 222 may be partially or entirely located within the insertion channel 21. Specifically, the second component 222 is used to move toward the interior of the insertion channel 21 when the airbag is filled with gas, and specifically, to move toward the central axis of the insertion channel 21.

[0035] In order to compress the capsule 30, the extruder 23 is fixed to the outer wall of the second component 222 and located inside the penetration channel 21.

[0036] In this embodiment, the elastic modulus of the first component 221 is greater than that of the second component 222. For example, the ratio of the elastic moduli of the first component 221 to the second component 222 can be 10 to 100:1, and can be set as needed.

[0037] Since the elastic modulus of the first component 221 is greater than that of the second component 222, when gas is filled into the inflation space, the second component 222 will deform preferentially, thereby driving the extruder 23 to move.

[0038] To achieve inflation, an inflation pipe 24 is fixedly installed on the outer wall of the conduit 20. The inflation pipe 24 is connected to the inflation space and is used to fill the inflation space with gas. The maximum amount of gas that can be filled into the inflation space without the airbag rupturing can be determined through testing. In this embodiment, both the first component 221 and the second component 222 have sufficient strength so that the airbag will not rupture even when the second component 222 completely blocks the penetration channel 21 when gas is filled into the inflation space.

[0039] In this embodiment, a sensing module 211 is provided inside the insertion channel 21, and a mating part 101 for being sensed by the sensing module 211 is provided on the drug delivery guide wire 10.

[0040] When the sensing module 211 senses the mating part 101, the drug delivery guide wire 10 is in a preset position relative to the catheter 20.

[0041] The portion of capsule 30 that protrudes beyond the drug delivery guide wire 10 is called the extension. When the drug delivery guide wire 10 is in a preset position, the squeeze member 23 is directly opposite the extension.

[0042] In this embodiment, the guidewire catheter device with drug delivery function also includes a guidewire for guiding the catheter 20. The structure of the guidewire can be referred to in the prior art, and will not be described in detail here.

[0043] Reference Figures 1-4 To facilitate understanding, the following is a brief explanation of how to use the guidewire catheter device: First, guide the catheter 20 using a guide wire so that the catheter 20 is inserted into the patient's body and the tip of the catheter 20 is located in the lesion area. Withdraw the guidewire, and then insert the drug delivery guidewire into the catheter 20 through the insertion channel 21; The position of the drug delivery guidewire 10 is adjusted so that the sensing module 211 senses the mating part 101. When the sensing module 211 senses the mating part 101, the drug delivery guidewire 10 is in a preset position relative to the catheter 20. Gas is injected into the inflation space of the airbag through the inflation pipe 24, thereby causing the airbag to expand. Since the elastic modulus of the first component 221 is greater than that of the second component 222, the second component 222 will deform preferentially after the inflation space is filled with gas, thereby driving the extruder 23 to move. After the extruder 23 moves a certain distance, it will contact and act on the protrusion of the capsule 30. As gas is continuously filled in, the force exerted by the extruder 23 on the capsule 30 will increase, thereby causing the capsule 30 to be ruptured. As capsule 30 ruptures, the medication inside is released, allowing it to flow precisely to the affected area.

[0044] Figure 4 The image shown is a magnified view. In the actual product, the distance between the extruder 23 and the opening 25 at the front end of the catheter 20 is generally about 1 to 5 mm. Correspondingly, when the drug delivery guidewire 10 is in the preset position relative to the catheter 20, the distance between the capsule 30 and the opening 25 at the front end of the catheter 20 is very close, approximately 1 to 5 mm.

[0045] In this embodiment, when the airbag is inflated, the second component 222 will first come into contact with the conical portion 102 of the drug delivery guide wire 10. As the airbag continues to expand, the second component 222 will fit more and more tightly with the conical portion 102 and form a seal. In this way, when the capsule 30 ruptures, the backflow of the drug can be prevented.

[0046] Furthermore, when the air bladder inflates, the curvature of the second component 222 increases, which can serve as a guide, allowing the medication flowing out of the capsule 30 to flow along the second component 222 and through the opening 25 at the front end of the catheter 20, and finally out to the outside of the catheter 20, thereby accurately flowing to the lesion area.

[0047] Because capsule 30 is very close to opening 25, the amount of medication remaining in catheter 20 after capsule 30 ruptures will be very small, almost negligible. Furthermore, since the preset position is fixed, the path length of the medication within the catheter is also fixed. Therefore, personnel can accurately measure the amount of medication remaining in catheter 20 through experiments. Thus, by maintaining a certain amount of medication in capsule 30, the dosage of medication flowing to the lesion area can be accurately controlled. Additionally, by inflating a certain amount of gas into the inflation space, the second component 222 expands and compresses the medication within catheter 20, allowing the medication to be fully and quickly expelled from catheter 20.

[0048] In this embodiment, the sensing module 211 includes a thin-film pressure sensor 41, and the mating part 101 includes a protrusion. The thin-film pressure sensor 41 has a ring-shaped structure and is disposed around the inner wall of the conduit; the protrusion is disposed around the outer wall of the drug delivery guidewire 10. The mating part is used to be sensed by the sensing module 211 by squeezing it. When the drug delivery guidewire 10 is in a preset position relative to the catheter 20, the protrusion squeezes the thin-film pressure sensor 41, thereby causing the thin-film pressure sensor 41 to generate a pressure signal.

[0049] A conduit may be installed on the outside of the conduit 20, and the wiring inside the conduit is electrically connected to the thin-film pressure sensor 41 to realize the transmission of electrical energy and signals through the wiring.

[0050] Reference Figure 5 In this embodiment, the thin-film pressure sensor 41 is connected to a control module 42 via a circuit. The control module 42 is connected to a display screen 43. When the thin-film pressure sensor 41 generates a pressure signal, the pressure signal is transmitted to the control module 42 via the circuit. The control module 42 processes the pressure signal and transmits the processed data to the display screen 43. Thus, medical personnel can determine whether the protrusion is pressing against the thin-film pressure sensor 41 based on the displayed pressure value, and thereby determine whether the drug delivery guidewire 10 is in a preset position relative to the catheter 20. Specifically, when the detected pressure value is within a preset range, the drug delivery guidewire 10 is in the preset position relative to the catheter 20. The control module 42 can be a processor or a microcontroller, etc.

[0051] In this embodiment, the protrusion and the drug delivery guidewire 10 can be an integral structure. In other embodiments, the protrusion can also be fixed to the drug delivery guidewire 10 by welding or other means.

[0052] Reference Figure 1 and Figure 6 In this embodiment, the capsule 30 is cylindrical, and the extruder 23 includes a concave and arc-shaped extrusion surface 231, which is used to conform to the outer surface of the capsule 30. By providing the extrusion surface 231, the extruder 23 can better cooperate with the capsule 30, ensuring that the extruder 23 can stably transmit force to the capsule 30, thereby causing the capsule 30 to rupture. The capsule 30 can be manufactured by a pharmaceutical company and can be available in different length specifications. Different specifications of capsule 30 store different dosages of medication, so that when doctors prescribe medication, they can select different specifications of capsule 30 according to the patient's condition.

[0053] To ensure even force distribution, multiple extrusion members 23 can be provided and arranged in a ring array. For example, the number of extrusion members 23 can be three, four, etc. The extrusion members 23 can be fixed to the outer wall of the second component 222 by means of laser welding or other methods.

[0054] In the description of this specification, the references to terms such as "one embodiment," "some embodiments," "example," "specific example," or "some examples," etc., refer to specific features, structures, materials, or characteristics described in connection with that embodiment or example, which are included in at least one embodiment or example of this application. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples. Moreover, without contradiction, those skilled in the art can combine and integrate the different embodiments or examples described in this specification, as well as the features of different embodiments or examples.

[0055] Although embodiments of this application have been shown and described above, it is understood that the above embodiments are exemplary and should not be construed as limiting this application. Those skilled in the art can make changes, modifications, substitutions and variations to the above embodiments within the scope of this application.

Claims

1. A guidewire catheter device with drug delivery function, characterized in that, It includes a drug delivery guidewire and a catheter, wherein the front end of the drug delivery guidewire is provided with a capsule, the capsule is filled with a drug, and the capsule portion protrudes from the surface of the drug delivery guidewire; The catheter is provided with an insertion channel and a driving structure; The insertion channel is used for the insertion of the drug delivery guidewire; The conduit is provided with a squeezing member, wherein the driving structure is used to drive the squeezing member so that the squeezing member ruptures the capsule; The drive structure includes an airbag, which is arranged around the duct. The catheter includes a first tube section and a second tube section, and the airbag is located between the first tube section and the second tube section, wherein both the first tube section and the second tube section are fixedly connected to the airbag. The airbag includes a first component and a second component that are sealed together, and an inflation space is formed between the first component and the second component. The inner walls of the first component and the second component are disposed opposite to each other, wherein the outer wall of the second component faces the insertion channel; the second component is used to move toward the inside of the insertion channel when the airbag is filled with gas; The extrusion member is fixed to the outer wall of the second component and is located inside the insertion channel; A sensing module is provided inside the insertion channel, and a mating part is provided on the drug delivery guidewire for being sensed by the sensing module. When the sensing module senses the mating part, the drug delivery guidewire is in a preset position relative to the catheter; The portion of the capsule that protrudes beyond the drug delivery guidewire is the extension portion; wherein, when the drug delivery guidewire is located at the preset position, the squeezing member is directly opposite the extension portion.

2. The guidewire catheter device with drug delivery function according to claim 1, characterized in that, The elastic modulus of the first component is greater than that of the second component.

3. The guidewire catheter device with drug delivery function according to claim 1, characterized in that, An inflation pipe is fixedly installed on the outer wall of the conduit; wherein, the inflation pipe is connected to the inflation space, and the inflation pipe is used to fill the inflation space with gas.

4. The guidewire catheter device with drug delivery function according to claim 1, characterized in that, The sensing module includes a thin-film pressure sensor, and the mating part includes a protrusion that surrounds the outer wall of the drug delivery guidewire; wherein the mating part is used to be sensed by the sensing module by squeezing the sensing module.

5. The guidewire catheter device with drug delivery function according to claim 1, characterized in that, The capsule is cylindrical, and the extruder includes a concave and arc-shaped extrusion surface for adhering to the outer surface of the capsule; there are multiple extruders, which are arranged in a ring array.

6. The guidewire catheter device with drug delivery function according to claim 1, characterized in that, It also includes a guidewire for guiding the catheter.

7. The guidewire catheter device with drug delivery function according to claim 1, characterized in that, The front end of the drug delivery guidewire is provided with an installation groove, and the capsule is embedded in the installation groove, wherein the capsule portion protrudes outside the installation groove.

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