Application of petroleum ether extract of isodon japonicus in preparation of medicine for treating non-small cell lung cancer

The petroleum ether extract of *Bungarus rotundus* root has solved the problem of large side effects of existing chemotherapy by inhibiting the proliferation of non-small cell lung cancer cells, inducing apoptosis and inhibiting metastasis, and providing a low-toxicity drug option for the treatment of non-small cell lung cancer.

CN117244001BActive Publication Date: 2026-05-29GUIZHOU UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
GUIZHOU UNIV
Filing Date
2023-09-20
Publication Date
2026-05-29

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Abstract

The application discloses application of a petroleum ether extract of Rhus copallinum L. in preparation of a medicine for treating non-small cell lung cancer. In the application, the petroleum ether extract of Rhus copallinum L. for treating non-small cell lung cancer is obtained by extracting roots of Rhus copallinum L. with a solvent petroleum ether. The petroleum ether extract can inhibit proliferation of non-small cell lung cancer cells through S phase arrest, can induce mitochondria-mediated apoptosis, and can inhibit migration and invasion, thereby exerting an antitumor biological effect, and has a prospect of research and development of a new antitumor medicine for treating non-small cell lung cancer.
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