A synergistic anti-dandruff composition and use thereof

Abstract

This invention relates to daily chemical products and discloses a synergistic anti-dandruff composition and its application. The anti-dandruff composition comprises the following raw materials in weight percentages: sodium lauryl ether sulfate 8.0-16.0%, cinnamaldehyde 1.0-3.0%, betaine 1.0-3.0%, and a solvent. The three raw materials in the anti-dandruff composition of this invention, when combined at specific concentrations, exhibit a synergistic effect in removing dandruff, forming a stable liquid crystal structure, thereby possessing excellent antibacterial ability, scalp cleansing ability, anti-inflammatory and antipruritic ability, moisturizing ability, and ability to promote scalp blood circulation.

Description

Technical Field

[0001] This invention relates to the field of daily chemical products, and more particularly to a synergistic anti-dandruff composition and its application. Background Technology

[0002] According to surveys, dandruff has become the second leading hair health problem in China, second only to hair loss. Approximately 60% of adults in my country suffer from dandruff to varying degrees. Currently, most chemical dandruff removers used in shampoos are broad-spectrum antibacterial agents, such as piroctone olamine, zinc pyrithione, and ketoconazole. Intermittent use can effectively inhibit the growth of bacteria and fungi, but long-term use can easily lead to a decrease in transepidermal moisture and lipids in the scalp, causing skin irritation and sensitization. The toxicity and safety of zinc pyrithione itself are also significant; the European Union banned its use as a dandruff remover in shampoos and conditioners in May 2022. With the rapid development of the anti-dandruff cosmetics market, new and highly effective dandruff-removing ingredients will inevitably emerge and be applied in cosmetics. The use and dosage of these ingredients not only affect the final efficacy and quality of cosmetics but also have a significant impact on consumer health. Therefore, researching and developing safe, gentle, and plant-based anti-dandruff products has a promising future.

[0003] Existing technologies also include numerous literatures on plant-based dandruff removal, all of which involve combinations of various plant extracts, including but not limited to aescin, soapberry seed extract, rhodiola rosea extract, lemongrass leaf oil, platycodon root extract, codonopsis root extract, cnidium monnieri extract, polygonum multiflorum extract, black sesame extract, Chinese cedar leaf extract, arborvitae leaf extract, salvia miltiorrhiza root extract, camellia seed extract, oat extract, black rice extract, tea tree essential oil, citronellol, and limonene alcohol. These combined solutions suffer from high costs, difficulty in controlling the purity of raw materials, and unsatisfactory dandruff removal effects.

[0004] Furthermore, the specific pathogenesis and biochemical changes of dandruff are not yet fully understood. Numerous studies report that excessive proliferation of Malassezia is a significant cause of dandruff, and a decrease or disappearance of Malassezia on the scalp directly reflects a reduction in dandruff. Shuster considers dandruff a Malassezia disease, while Pan Jingling and Wei Shiyu proposed that restrictive Malassezia is the dominant fungal species in dandruff. However, most current research on dandruff treatment efficacy uses the ability to inhibit Malassezia furfur as an indicator, neglecting the ability to inhibit restrictive Malassezia. Summary of the Invention

[0005] To address the aforementioned technical problems, this invention provides a synergistic anti-dandruff composition and its application. The three raw materials in this anti-dandruff composition, when combined in specific amounts, exhibit a synergistic effect in dandruff removal, forming a stable liquid crystal structure, thereby possessing excellent antibacterial ability, scalp cleansing ability, anti-inflammatory and antipruritic ability, moisturizing ability, and ability to promote scalp blood circulation.

[0006] The specific technical solution of this invention is as follows:

[0007] In a first aspect, the present invention provides a synergistic anti-dandruff composition comprising the following raw materials in weight percentages: sodium lauryl ether sulfate 8.0-16.0%, cinnamaldehyde 1.0-3.0%, betaine 1.0-3.0%, and solvent.

[0008] The anti-dandruff composition of this invention mainly includes cinnamaldehyde, betaine, and sodium lauryl ether sulfate. This anti-dandruff composition has excellent inhibitory ability against both Malassezia restricta and Malassezia furfur, thereby achieving excellent anti-dandruff effects. Through research, this invention has found that the combination of cinnamaldehyde, betaine, and sodium lauryl ether sulfate can have a significant synergistic effect in anti-dandruff and scalp care. This is because the composition forms a stable liquid crystal structure that can act evenly on the scalp. We found that compared with traditional anti-dandruff products, this liquid crystal structure has the following effects: (1) It can continuously interfere with the biofilm and metabolic processes of Malassezia cells, thereby inhibiting the growth and reproduction of Malassezia for a long time, reducing its number and activity, and thus reducing the generation of dandruff; (2) The presence of the liquid crystal structure is more conducive to the continuous penetration of active ingredients into the deep layers of the scalp, dissolving oil and... (3) The presence of liquid crystal structure is conducive to the better penetration of active ingredients into the scalp skin, inhibiting inflammatory response and the release of inflammatory cells, and relieving the itching symptoms caused by dandruff; (4) The presence of liquid crystal structure enables betaine to continuously provide the scalp with the required moisture and enhance the scalp's water retention capacity, preventing the scalp from drying out and flaking; (5) The presence of liquid crystal structure enables cinnamaldehyde to continuously increase the dilation of scalp capillaries and blood flow, promote scalp blood circulation, improve the scalp's nutritional supply and metabolic detoxification capacity, and good scalp blood circulation helps reduce the formation of dandruff.

[0009] In summary, the dandruff-reducing composition of the present invention has complex effects such as inhibiting fungal growth, anti-inflammatory and antipruritic, cleaning and dissolving oil, moisturizing and nourishing the scalp, and promoting scalp blood circulation, thereby reducing dandruff production and achieving scalp care from multiple angles.

[0010] It should be further noted that, through experiments, this invention has found that the above three raw materials are irreplaceable to a certain extent. The absence or replacement of any one of them will disrupt their interaction and balance, thereby leading to a deterioration in the dandruff removal effect.

[0011] The reason for choosing sodium lauryl ether sulfate in this invention is that, compared to other types of surfactants, it can form a denser and more viscoelastic interfacial film at the oil-water interface in the system of this invention, thereby better regulating the surface tension of the liquid crystal, promoting the orderly arrangement of liquid crystal molecules, and thus making the system more stable. Betaine is chosen in this invention because it can serve as a molecular additive for liquid crystal formation in the composition, playing a very important role in the formation, arrangement, and orientation of liquid crystal molecules. In the system, it is tightly bound to cinnamaldehyde through hydrogen bonds, forming a more orderly and well-organized liquid crystal structure within the micelles of sodium lauryl ether sulfate.

[0012] Furthermore, this invention also reveals that not all compositions of the above three raw materials in arbitrary proportions exhibit significant synergistic effects; rather, a certain content range is required. Specifically, sodium lauryl ether sulfate, as the primary emulsifier for liquid crystal formation, is susceptible to adverse effects if its concentration is too low, as this hinders complete emulsification of cinnamaldehyde and easily leads to unstable liquid crystal structures. Conversely, excessively high concentrations result in complete solubility of cinnamaldehyde, preventing liquid crystal formation and thus affecting the antibacterial effect. Betaine acts as an adjuvant in liquid crystal formation, enhancing the stability of the liquid crystal system through its aggregation network with the primary emulsifier. However, excessively low betaine concentrations lead to incomplete liquid crystal structure formation and system instability, while excessively high concentrations cause liquid crystal formation to occur too quickly, resulting in uneven particle size and compromising system stability. Excessively high cinnamaldehyde concentrations result in excessively close inter-liquid crystals with overly strong interactions, negatively impacting liquid crystal formation and stability. Conversely, excessively low concentrations allow for complete solubility by lauryl ether sulfate, preventing liquid crystal formation.

[0013] Preferably, sodium lauryl ether sulfate comprises 10.0-13.0%, cinnamaldehyde 1.5-2.5%, betaine 1.5-2.5%, and solvent. More preferably, sodium lauryl ether sulfate comprises 12.0%, cinnamaldehyde 1.5%, betaine 1.5%, and solvent.

[0014] Preferably, the solvent is water.

[0015] Preferably, the synergistic anti-dandruff composition further includes one or more of preservatives, pH adjusters, viscosity modifiers, hair conditioning agents, and fragrances.

[0016] Secondly, the present invention provides the application of a composition of sodium lauryl ether sulfate, cinnamaldehyde and betaine as an anti-dandruff ingredient in shampoos.

[0017] Preferably, the mass percentages of each ingredient in the composition in the shampoo are: sodium lauryl ether sulfate 8.0-16.0%, cinnamaldehyde 1.0-3.0%, and betaine 1.0-3.0%. More preferably, the composition is: sodium lauryl ether sulfate 10.0-13.0%, cinnamaldehyde 1.5-2.5%, and betaine 1.5-2.5%. Most preferably, the composition is: sodium lauryl ether sulfate 12.0%, cinnamaldehyde 1.5%, and betaine 1.5%.

[0018] Compared with the prior art, the beneficial effects of the present invention are:

[0019] (1) The dandruff-removing composition of the present invention has excellent inhibitory ability against both Malassezia restricta and Malassezia furfur, thereby achieving excellent dandruff removal effect.

[0020] (2) The cinnamaldehyde, betaine and sodium lauryl ether sulfate in the anti-dandruff composition of the present invention can have a synergistic effect when combined at a specific content, forming a stable liquid crystal structure, thereby having excellent antibacterial ability, scalp cleaning ability, anti-inflammatory and antipruritic ability, moisturizing ability and scalp blood circulation promotion ability. Attached Figure Description

[0021] Figure 1 The images show scalp photographs of some of the test subjects in Examples 1-5 and Comparative Examples 1-7.

[0022] Figure 2 These are microscope images of the compositions obtained in some of the embodiments and comparative examples. Detailed Implementation

[0023] The present invention will be further described below with reference to embodiments.

[0024] General Implementation Examples

[0025] A synergistic anti-dandruff composition comprises the following raw materials in weight percentages: sodium lauryl ether sulfate 8.0-16.0%, cinnamaldehyde 1.0-3.0%, betaine 1.0-3.0%, and solvent. Preferably, the composition includes sodium lauryl ether sulfate 10.0-13.0%, cinnamaldehyde 1.5-2.5%, betaine 1.5-2.5%, and solvent. More preferably, the composition includes sodium lauryl ether sulfate 12.0%, cinnamaldehyde 1.5%, betaine 1.5%, and solvent.

[0026] Preferably, the solvent is water. Preferably, the synergistic anti-dandruff composition further includes one or more of a preservative, pH adjuster, viscosity adjuster, hair conditioner, and fragrance.

[0027] The application of a composition of sodium lauryl ether sulfate, cinnamaldehyde, and betaine as an anti-dandruff ingredient in shampoos. Preferably, the mass percentages of each ingredient in the composition in the shampoo are: sodium lauryl ether sulfate 8.0-16.0%, cinnamaldehyde 1.0-3.0%, and betaine 1.0-3.0%. More preferably, sodium lauryl ether sulfate 10.0-13.0%, cinnamaldehyde 1.5-2.5%, and betaine 1.5-2.5%. Most preferably, sodium lauryl ether sulfate 12.0%, cinnamaldehyde 1.5%, and betaine 1.5%.

[0028] Specific Examples and Comparative Examples (I) To determine the optimal compound content among sodium lauryl ether sulfate, cinnamaldehyde, and betaine, the following experiments were conducted. For convenience, the following experiments are based solely on the inhibition rates against two Malassezia species. The experimental protocol and data are as follows:

[0029] (1) The amount of cinnamaldehyde and betaine added is 2% according to the empirical value. The antibacterial rate of sodium laureth sulfate at different addition amounts is compared, and the remainder is made up to 100% with water.

[0030] Table 1

[0031]

[0032] As shown in Table 1, the composition exhibits the best antibacterial rate against Malassezia furfur and Malassezia restriction when the sodium lauryl ether sulfate content is in the range of 8–16%. As the primary emulsifier for liquid crystal formation, sodium lauryl ether sulfate, if added in too low a concentration, hinders complete emulsification of cinnamaldehyde, resulting in an unstable liquid crystal structure; conversely, if added in too high a concentration, it leads to insufficient solubilization of cinnamaldehyde, preventing liquid crystal formation and thus affecting the antibacterial effect.

[0033] (2) Sodium lauryl ether sulfate 12%, cinnamaldehyde 2%, compare the antibacterial rate of betaine at different addition amounts, and make up the remainder with water to 100%.

[0034] Table 2

[0035]

[0036]

[0037] Table 2 shows that the composition exhibits the best antibacterial rate against Malassezia furfur and Malassezia restriction when the betaine content is in the range of 1-3%. Betaine acts as an auxiliary agent in the liquid crystal formation process. This auxiliary agent can improve the stability of the liquid crystal system by binding with the main emulsifier to form a coagulation network. If the amount of betaine added is too low, the liquid crystal structure will not form completely, leading to system instability; conversely, if the amount added is too high, the liquid crystal will form too quickly, resulting in uneven particle size and compromising the stability of the system.

[0038] (3) Sodium lauryl ether sulfate 12%, betaine 2%, compare the antibacterial rate of cinnamaldehyde at different addition amounts, and make up the remainder with water to 100%.

[0039] Table 3

[0040]

[0041] Table 3 shows that the composition exhibits the best antibacterial rate against Malassezia furfur and Malassezia restriction when the cinnamaldehyde content is in the range of 1-3%. When the concentration of cinnamaldehyde is too high, the liquid crystals are too close together, resulting in excessively strong interactions and negatively impacting the morphology and stability of the liquid crystals. When the concentration is too low, it will be completely solubilized by lauryl ether sulfate, preventing the formation of liquid crystals.

[0042] (4) Investigate the changes in antibacterial rate when one of the raw materials in the composition is outside the range, while the other two raw materials are within the range.

[0043] Table 4

[0044]

[0045]

[0046] As can be seen from the data in Table 4, the antibacterial effect is not ideal when any of the three raw materials is not within the preferred range of the present invention.

[0047] (ii) In vitro tests were conducted on the minimum inhibitory concentration, inhibition rate and inhibition zone of two Malassezia species for compositions with different formulations.

[0048] Table 5

[0049]

[0050]

[0051] Note: Since cinnamaldehyde is an oily liquid, it cannot be dissolved and dispersed in water alone or together with betaine without sodium lauryl ether sulfate. Therefore, Table 5 does not include cinnamaldehyde alone or a comparative ratio of cinnamaldehyde and betaine.

[0052] (1) Minimum inhibitory concentration (MIC) test method

[0053] Referring to and improving upon the agar dilution method in section 2.1.8.3 of the 2002 edition of the "Disinfection Technical Specifications," a 1% (w / w) antidandruff component was added to a blank shampoo sample without antidandruff. The shampoo was serially diluted to different concentrations (based on the mass of the antidandruff). Simultaneously, double-concentration culture media corresponding to two different Malassezia strains were prepared and sterilized. 9 ml of each serially diluted shampoo solution was placed in a petri dish, and 9 ml of double-concentration culture media (approximately 50°C) was added to the dish. After mixing and allowing it to solidify, one drop of the bacterial suspension was inoculated onto the surface of the culture medium containing the antidandruff, with 3-4 inoculations per dish. The dishes were incubated at 32°C for 7 days, and the results were observed. A lower MIC value indicates a stronger inhibitory effect on the bacteria.

[0054] Malassezia furfur (ATCC44344), Guangdong Provincial Microbial Culture Collection Center; Malassezia restricta (ATCC96810), purchased from the China Microbial Culture Collection Network; Sabouraud dextrose agar (SDA), BD Biosciences, USA; ox bile salts and nutrient broth, Guangdong Huankai Microbial Technology Co., Ltd.; polysorbate 40, Shanghai Aladdin Biochemical Technology Co., Ltd. The culture medium used for Malassezia furfur was Sabouraud dextrose agar supplemented with 1% Tween 40 and 0.5% ox bile salts; the culture medium used for Malassezia restricta was Sabouraud dextrose agar supplemented with 1% Tween 40.

[0055] Table 6

[0056] Malassezia furfur, ppm Malassezia, ppm Example 1 50 50 Example 2 45 45 Example 3 50 45 Example 4 45 50 Example 5 45 50 Example 6 50 50 Example 7 45 45 Comparative Example 1 130 150 Comparative Example 2 125 150 Comparative Example 3 130 145 Comparative Example 4 135 145 Comparative Example 5 130 155 Comparative Example 6 125 155 Comparative Example 7 130 130 Comparative Example 8 185 210

[0057] As shown in Table 6, compared to Comparative Examples 1-6, the MICs of Examples 1-7 against *Malassezia furfur* and *Malassezia restricta* were significantly lower. The reason for this is that the content of at least one ingredient in Comparative Examples 1-6 was outside the optimized range. This demonstrates that the significant synergistic effect of sodium lauryl ether sulfate, betaine, and cinnamaldehyde in the system of this invention requires maintaining a balance within a reasonable content ratio range. When the content of any ingredient disrupts this balance, it will significantly affect the effect.

[0058] Comparing Example 2 and Comparative Examples 7-8, the difference lies in the absence of cinnamaldehyde and betaine in the compositions of Comparative Examples 7-8, respectively. The results showed that the antibacterial activity of Comparative Examples 7-8 was significantly reduced compared to Example 2. This indicates that only through the synergistic effect of the three components can a lower MIC be achieved, resulting in a stronger inhibitory effect against the two Malassezia species.

[0059] (2) Evaluation of antibacterial rate

[0060] Referring to the suspension quantitative method in QB / T 2738-2012 "Evaluation Method for Antibacterial and Bacteriostatic Effects of Daily Chemical Products", the shampoo concentration was 50%, and the reaction time was 2 minutes. After the product test concentration sample solution and the added bacteria had reacted, 1 mL of the sample was directly taken into a petri dish for colony counting. At the same time, it was also serially diluted 10 times for viable bacteria counting. After solidification, the petri dish was inverted and incubated at 32℃ for 7 days. The antibacterial rate was then calculated. The higher the antibacterial rate, the better the inhibitory effect on bacteria.

[0061] Table 7

[0062] Malassezia furfur, % Restrictive Malassezia, % Example 1 >99.9 99.6 Example 2 >99.9 99.8 Example 3 >99.9 >99.9 Example 4 >99.9 >99.9 Example 5 >99.9 >99.9 Example 6 >99.9 >99.9 Example 7 >99.9 99.6 Comparative Example 1 45.6 34.7 Comparative Example 2 47.2 36.8 Comparative Example 3 45.3 35.1 Comparative Example 4 46.5 29.8 Comparative Example 5 48.3 37.2 Comparative Example 6 49.2 32.9 Comparative Example 7 45.4 37.3 Comparative Example 8 0 0

[0063] As shown in Table 7, compared to Comparative Examples 1-7, Examples 1-7 exhibited significantly better inhibition rates against Malassezia furfur and Malassezia restriction. In particular, Example 2, compared to Comparative Examples 7 and 8, demonstrates that only through synergistic interaction among the three components can a lower MIC be achieved, resulting in a stronger inhibitory effect against Malassezia. Comparative Examples 1-6 show that only when all three components are within the combined content range defined in this invention can the anti-dandruff composition exhibit a good synergistic inhibitory effect against Malassezia furfur and Malassezia restriction.

[0064] (3) Evaluation of inhibition zone

[0065] The experiment was conducted with reference to and improvements to section 2.1.8 of the 2002 edition of the "Disinfection Technical Specifications". Specific operating steps: Use a punch to cut qualitative filter paper into 6mm diameter circles. After autoclaving, dry them in an oven. Add 20µL of 50% shampoo solution to each circle of filter paper and dry in a 47℃ oven. Prepare a bacterial suspension of activated Malassezia. Add 1mL to the surface of the Malassezia culture medium, and shake the petri dish at multiple angles for 2-3 minutes to evenly distribute the bacterial suspension on the surface. Remove excess bacterial suspension from the petri dish, partially open the lid, and air dry the surface moisture on a clean bench. Use tweezers to pick up the dried filter paper containing the shampoo solution and place it firmly against the surface of the culture medium, 3-4 pieces per dish. Cover the petri dish and incubate at 32℃ for approximately 40 hours. Measure the diameter of the inhibition zone with calipers; if ≤7mm, no antibacterial effect is considered.

[0066] Table 8

[0067] Malassezia furfur, mm Restrictive Malassezia, mm Example 1 21.3 19.4 Example 2 22.1 19.6 Example 3 21.5 18.7 Example 4 22.3 19.1 Example 5 25.4 20.2 Example 6 20.5 18.9 Example 7 21.3 19.2 Comparative Example 1 8.1 7.6 Comparative Example 2 8.6 7.4 Comparative Example 3 8.2 7.6 Comparative Example 4 8.1 7.2 Comparative Example 5 9.3 7.9 Comparative Example 6 8.2 7.3 Comparative Example 7 8.6 7.3 Comparative Example 8 ≤7 ≤7

[0068] As shown in Table 8, compared to Comparative Examples 1-7, Examples 1-7 exhibited significantly better inhibition rates against *Malassezia furfur* and *Malassezia restricta*. In particular, Example 2, despite having the same cinnamaldehyde concentration as Comparative Example 7, lacked the synergistic effect of betaine, resulting in a significantly lower inhibition rate and weaker inhibitory effect against *Malassezia*. Comparative Example 8 showed very poor antibacterial effect when only sodium lauryl ether sulfate and betaine were present. Comparative Examples 1-6 demonstrate that only when all three components are within the combined content range defined in this invention can the anti-dandruff composition exhibit a good synergistic inhibitory effect against *Malassezia furfur* and *Malassezia restricta*.

[0069] (4) Consumer evaluation of dandruff removal

[0070] Shampoos from Examples 1-7 and Comparative Examples 1-7 were adjusted to suitable pH and viscosity. Seventy test subjects with dandruff and itchy scalp were selected, divided into groups of five. Following their usual habits, they used the shampoos from the Examples and Comparative Examples for 14 and 28 consecutive days. The degree of improvement in dandruff is shown in Table 9. Photos of the scalp and dandruff were taken using a VisioScan VC20 to assess their condition. Figure 1 .

[0071] Table 9

[0072]

[0073]

[0074] As shown in Table 9, compared to Comparative Examples 1-7, most test subjects experienced improvement in dandruff and scalp itching after continuous use of Examples 1-7 for 14 and 28 days. In particular, Example 2, compared to Comparative Example 7, had the same concentration of cinnamaldehyde but lacked the synergistic effect of betaine, resulting in poorer dandruff and itch relief. Comparative Example 8 showed very poor dandruff and itch relief when only sodium lauryl ether sulfate and betaine were present. Comparative Examples 1-7 demonstrate that the dandruff-reducing composition only exhibits good dandruff and itch relief effects within the combined content range specified in this invention.

[0075] from Figure 1 It can be seen that after 14 and 28 days of continuous use of the anti-dandruff compositions of each embodiment, the dandruff condition of the test subjects improved significantly (obvious dandruff was present on D0, and almost no dandruff was present on D14 and D28); while in the comparative examples, obvious dandruff was still observed on D14 and D28, indicating that the anti-dandruff effect was not ideal. Therefore, it is evident that the selection and content range of each raw material in the system of this invention have a significant impact on the anti-dandruff effect.

[0076] (5) Microscopic observation

[0077] The compositions obtained in Example 2, Comparative Examples 7, and 8 were observed under a microscope. Figure 2As can be seen, the composition obtained in Example 2 (top image) exhibits a clear liquid crystal structure under a microscope, while the liquid crystal structures in Comparative Example 7 (middle image) and Comparative Example 8 (bottom image) are not as obvious. This indicates that a uniform and stable liquid crystal structure can only be formed when sodium lauryl ether sulfate, cinnamaldehyde, and betaine are present simultaneously.

[0078] Unless otherwise specified, the raw materials and equipment used in this invention are all commonly used in the field; unless otherwise specified, the methods used in this invention are all conventional methods in the field.

[0079] The above description is merely a preferred embodiment of the present invention and is not intended to limit the present invention in any way. Any simple modifications, alterations, and equivalent transformations made to the above embodiments based on the technical essence of the present invention shall still fall within the protection scope of the present invention.

Claims

1. A synergistic antidandruff composition characterized in that made from the following raw materials in mass percent: sodium lauryl ether sulfate 8.0-16.0%, cinnamaldehyde 1.0-3.0%, betaine 1.0-3.0%, a solvent.

2. The synergistic antidandruff composition according to claim 1, wherein made from the following raw materials in mass percent: sodium lauryl ether sulfate 10.0-13.0%, cinnamaldehyde 1.5-2.5%, betaine 1.5-2.5%, a solvent.

3. The synergistic antidandruff composition according to claim 2, wherein made from the following raw materials in mass percent: sodium lauryl ether sulfate 12.0%, cinnamaldehyde 1.5%, betaine 1.5%, a solvent.

4. The synergistic antidandruff composition according to any one of claims 1 to 3, characterized in that: The solvent is water.

5. The synergistic antidandruff composition according to any one of claims 1 to 3, wherein: One or more of a preservative, a pH adjuster, a viscosity adjuster, a hair conditioner, and a fragrance are also added.

6. Use of the synergistic antidandruff composition of claim 1 as an antidandruff ingredient in the preparation of a shampoo.

7. Use according to claim 6, wherein: The mass percent of each raw material in the composition is: sodium lauryl ether sulfate 10.0-13.0%, cinnamaldehyde 1.5-2.5%, betaine 1.5-2.5%.

8. Use according to claim 7, wherein: The mass percent of each raw material in the composition is: sodium lauryl ether sulfate 12.0%, cinnamaldehyde 1.5%, betaine 1.5%.

9. The use according to claim 6, characterized in that: The solvent is water.

10. The use according to claim 6, characterized in that: One or more of a preservative, a pH adjuster, a viscosity adjuster, a hair conditioner, and a fragrance are also added. The mass percent of each raw material in the composition is: sodium lauryl ether sulfate 10.0-13.0%, cinnamaldehyde 1.5-2.5%, betaine 1.5-2.5%. The mass percent of each raw material in the composition is: sodium lauryl ether sulfate 12.0%, cinnamaldehyde 1.5%, betaine 1.5%. The solvent is water. One or more of a preservative, a pH adjuster, a viscosity adjuster, a hair conditioner, and a fragrance are also added.

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