Vaccine negative pressure sealing bottle for pig farm breeding

Abstract

This invention relates to a negative pressure sealing bottle for pig farm vaccines, belonging to the field of animal husbandry technology. It includes a bottle body and a stopper. The upper part of the bottle body has a narrowed neck. The stopper consists of an upper plate, a silicone capsule, and a lower plate. The upper plate is fixed to the surface of the silicone capsule, and the other surface of the silicone capsule is fixed to the lower plate. An injection hole for inserting a needle is provided on the upper plate. This invention utilizes the principle of negative pressure to seal the mouth of the glass bottle containing the vaccine. It is simple to operate and easy to open when using the vaccine. After the negative pressure sealing stopper has been sealed for a period of time, outside air enters the silicone capsule cavity through the gaps between the silicone molecules, reducing the negative pressure inside the silicone capsule cavity and bringing it closer to equilibrium with the external atmospheric pressure. Loosening the bottom stopper seals the bottle mouth, allowing users to easily determine if the vaccine has expired. This device can effectively preserve vaccines for a long time, facilitates user judgment of vaccine expiration, and is easy to open when using the vaccine. It is highly operable, simple to manufacture, low in cost, and has significant effects.

Description

Technical Field

[0001] This invention belongs to the field of animal husbandry technology, and mainly relates to negative pressure sealing bottles for vaccines used in pig farms. Background Technology

[0002] Since the 1990s, China's pig industry has undergone tremendous changes, with large-scale, intensive pig production systems gradually replacing the family-based farming model. Currently, the main threats to the pig industry are unstable pig prices, infectious diseases, and diseases in breeding sows. Therefore, the use of vaccines is becoming increasingly widespread, with a large number of vaccines being applied to pig production each year. However, most commercially available vaccines are packaged in glass containers, typically sealed with aluminum or tinplate caps, making them difficult to open and prone to causing cuts. For example, injections are also prone to causing cuts. Lactation bottles with rubber stoppers and aluminum caps are extremely difficult to open without special tools. Furthermore, vaccines are generally expensive, and because they are intended for pigs, many people believe that simply injecting them will prevent disease. Therefore, it is difficult to identify whether the vaccine is within its expiration date, leading to the use of expired vaccines in production. Once the vaccine's efficacy decreases, it can severely impact production. Summary of the Invention

[0003] The present invention aims to overcome the shortcomings of the prior art and provides a negative pressure sealing bottle for vaccines used in pig farms. By using the principle of negative pressure, the mouth of the glass bottle containing the vaccine is sealed with a negative pressure sealing bottle stopper. The negative pressure generated during the manufacturing of the silicone capsule inside the negative pressure sealing bottle stopper can then plug and seal the bottle mouth.

[0004] The present invention relates to a negative pressure sealing bottle for pig farm vaccines, comprising a bottle body and a stopper. The upper part of the bottle body is a narrowed bottle mouth. The stopper is composed of an upper stopper plate, a silicone capsule, and a lower stopper plate. The silicone capsule is a hollow capsule structure. The upper stopper plate is fixed to the surface of the silicone capsule, and the other surface of the silicone capsule, which is symmetrical to the upper stopper plate, is fixed to the lower stopper plate. An injection hole for inserting a needle is provided at the center of the upper stopper plate.

[0005] As a further improvement of the present invention, the silicon capsule is formed by a cavity consisting of a silicon capsule sidewall, a top wall, and a bottom wall. The silicon capsule sidewall has a structure that is thick in the middle and thin at the top and bottom ends, and the top wall and bottom wall have the same thickness.

[0006] As a further improvement of the present invention, the lower surface of the upper plate of the bottle stopper is fixed to the top wall of the silicone capsule, and the upper surface of the lower plate of the bottle stopper is fixed to the bottom wall of the silicone capsule.

[0007] As a further improvement of the present invention, the diameter of the upper plate of the bottle stopper is larger than the inner diameter of the bottle mouth, and the diameter of the lower plate of the bottle stopper is smaller than the inner diameter of the bottle mouth.

[0008] As a further improvement of the present invention, the upper plate of the bottle stopper is made of plastic, copper, stainless steel or aluminum alloy, and has a thickness of 1-2 mm.

[0009] As a further improvement of the present invention, the lower plate of the stopper is made of plastic, copper, stainless steel or aluminum alloy, and has a thickness of 1-2 mm.

[0010] As a further improvement of the present invention, the bottle body is made of glass and has a thickness of 0.5-2 mm.

[0011] This invention relates to a negative pressure sealing bottle for pig farm vaccines. Its structure is rationally designed, utilizing the principle of negative pressure to seal the glass bottle containing the vaccine with a stopper. Operation is simple and convenient, and it is also easy to open when using the vaccine. Because of the gaps between the silicone molecules, after a period of sealing, outside air enters the silicone capsule cavity through these gaps, gradually reducing the negative pressure inside the capsule until it reaches equilibrium with the external atmospheric pressure. This allows the stopper to loosen, enabling users to determine if the vaccine is expired and preventing the sale of expired vaccines. This device effectively preserves vaccines over a long period, allows users to easily determine expiration dates, and is easy to open when using the vaccine. It is highly operable, simple to manufacture, low in cost, and has significant effects. Attached Figure Description

[0012] Figure 1 This is a cross-sectional view of the present invention;

[0013] Figure 2 This is a schematic diagram of the bottle stopper structure of the present invention;

[0014] Figure 3 This is a cross-sectional view of the bottle stopper of the present invention. Implementation

[0015] The present invention relates to a negative pressure sealing bottle for pig farm vaccines, comprising a bottle body 1 and a stopper 2. The bottle body 1 is made of glass with a thickness of 0.5-2 mm. The upper part of the bottle body 1 has a narrowed mouth. The upper surface of the bottom of the bottle body 1 is concave downwards, with the maximum concavity at its center and a depth of 1-2 mm, which facilitates the complete removal of the vaccine. The lower surface of the bottom of the bottle body 1 is concave upwards, with the maximum concavity at its center and a depth of 0.5-1 mm, which increases the stability of the bottle body 1 when it is placed.

[0016] The bottle stopper 2 is composed of an upper stopper plate 3, a silicone capsule 4, and a lower stopper plate 5. The upper stopper plate 3 is made of plastic, copper, stainless steel, or aluminum alloy, with a thickness of 1-2 mm and a diameter larger than the inner diameter of the bottle mouth of the bottle body 1. The lower surface of the upper stopper plate 3 is adhered to the top wall of the silicone capsule 4 with adhesive. A pin injection hole 6 with a diameter of 0.5-1 mm is provided at the center of the upper stopper plate 3. The silicone capsule 4 is a hollow capsule structure, consisting of the surrounding silicone capsule side walls 7, top wall, and bottom wall. The cavity formed is a silicone capsule cavity 8. The sidewall 7 of the silicone capsule is made of silicone, which is soft and elastic. It has a structure that is thick in the middle and thin at the top and bottom ends. The thickness in the middle is 1-5 mm and the thickness at the top and bottom ends is 0.5-1 mm. The thickness of the top wall and the bottom wall is the same, both being 0.5-1 mm. The lower stopper plate 5 is made of plastic, copper, stainless steel or aluminum alloy, with a thickness of 1-2 mm and a diameter smaller than the inner diameter of the bottle mouth of the bottle body 1. The upper surface of the lower stopper plate 5 is adhered to the bottom wall of the silicone capsule 4 with adhesive.

[0017] Instructions for use: First, fill a certain amount of swine disease prevention vaccine into bottle 1. Insert bottle stopper 2 into the bottle opening of bottle 1, so that the lower surface of the upper plate 3 of the stopper rests against the upper end of the bottle opening of bottle 1. Then, insert the syringe needle through the injection hole 6 and puncture the top wall of the silicone capsule 4, connecting the syringe cavity with the silicone capsule cavity 8. Use the syringe to extract the air from the silicone capsule cavity 8. Because the diameter of the upper plate 3 of the stopper is larger than the inner diameter of the bottle opening, it can prevent the entire stopper 2 from collapsing into the bottle opening. And because the diameter of the lower plate 5 of the stopper is smaller than the inner diameter of the bottle opening, the bottom wall of the silicone capsule 4 will move the lower plate 5 of the stopper upwards during the process of the syringe extracting air. Because the side wall 7 of the silicone capsule is thick in the middle and gradually thins from the middle to the upper and lower sides respectively, the lower plate of the stopper... During the upward movement of stopper 5, the thinner silicone capsule sidewall 7 fills the space between the lower stopper plate 5 and the inner wall of the bottle mouth. The less gas in the silicone capsule cavity 8, the lower the air pressure, creating a pressure difference with the external atmospheric pressure. The greater the upward movement of the lower stopper plate 5, the more silicone capsule sidewall 7 fills the space between the lower stopper plate 5 and the inner wall of the bottle mouth, resulting in a stronger sealing force and a tighter seal. This makes the stopper 2 a stopper that can seal the bottle mouth with negative pressure. After the air in the silicone capsule cavity 8 is evacuated to a certain extent, the syringe is pulled out, and the injection hole 6 of the needle is sealed with adhesive. The part of the silicone capsule sidewall 7 that is squeezed between the lower stopper plate 5 and the inner wall of the bottle mouth forms an outward-flowing adhesive wall, which firmly seals the gap between the lower stopper plate 5 and the inner wall of the bottle mouth, completing the sealing of the bottle body 1.

[0018] When it is necessary to use the vaccine in bottle 1 and remove the stopper 2 from the bottle opening, a syringe filled with air can be inserted through the air injection hole 6. The needle tip pierces the top wall of the silicone capsule 4 and enters the silicone capsule cavity 8. Then, push the syringe handle to inject air into the silicone capsule cavity 8, filling the silicone capsule cavity 8 with air. This causes the lower plate 5 of the stopper to move down, the negative pressure to disappear, and the outflowing rubber wall to shrink, thus allowing the stopper 2 to be easily pulled out without obstruction, and the vaccine in bottle 1 can then be used.

[0019] The vaccines mentioned above are inactivated vaccines, attenuated vaccines, monovalent vaccines, multivalent vaccines, mixed vaccines, homologous vaccines, heterologous vaccines, subunit vaccines, live vector vaccines, gene-deleted vaccines, and nucleic acid vaccines used to prevent and treat swine diseases. Examples include inactivated foot-and-mouth disease vaccines for swine, attenuated live vesicular swine disease vaccines for swine, inactivated porcine circovirus vaccines for swine circovirus disease, gene-deleted marker vaccines or inactivated vaccines for swine pseudorabies, wet or freeze-dried vaccines for swine fever, oral attenuated live swine pneumonia vaccines for swine pneumonia, and multivalent Escherichia coli vaccines for swine coli infection.

Claims

1. A negative pressure sealed bottle for vaccines used in pig farms, comprising a bottle body (1) and a stopper (2), wherein the upper part of the bottle body (1) is a narrowed bottle mouth, characterized in that... The bottle stopper (2) is composed of an upper stopper plate (3), a silicone capsule (4), and a lower stopper plate (5). The silicone capsule (4) is a hollow capsule structure. The upper stopper plate (3) is fixed to the surface of the silicone capsule (4), and the other surface of the silicone capsule (4) is fixed to the lower stopper plate (5). The upper stopper plate (3) has a needle injection hole (6) at its center. The silicone capsule (4) is formed by the cavity of the silicone capsule sidewalls (7), top wall, and bottom wall. The silicone capsule sidewalls (7) are thick in the middle and thin at the top and bottom. The top wall and bottom wall have the same thickness. The lower surface of the upper stopper plate (3) is fixed to the top wall of the silicone capsule (4), and the upper surface of the lower stopper plate (5) is fixed to the bottom wall of the silicone capsule (4). The bottle body (1) is made of glass and has a thickness of 0.5-2 mm. When in use, insert the syringe needle into the injection hole (6) and puncture the top wall of the silicone capsule (4) so ​​that the inner cavity of the syringe is connected to the silicone capsule cavity (8). Use the syringe to draw out the air in the silicone capsule cavity (8). The bottom wall of the silicone capsule (4) will move the lower stopper plate (5) upward. After the air in the silicone capsule cavity (8) is drawn to a certain extent, pull out the syringe and seal the injection hole (6) with adhesive. The side wall (7) of the silicone capsule is squeezed to the part between the lower stopper plate (5) and the inner wall of the bottle mouth to form an outward adhesive wall, which firmly seals the gap between the lower stopper plate (5) and the inner wall of the bottle mouth, thus completing the sealing of the bottle body (1). After the negative pressure sealing stopper has been sealed for a period of time, outside air will enter the silicone capsule cavity through the gaps between the silicone molecules, gradually reducing the negative pressure inside the silicone capsule cavity until it tends to balance with the outside atmospheric pressure. Finally, the bottom stopper is loosened from the bottle opening to determine whether the vaccine has expired.

2. The negative pressure sealing bottle for pig farm vaccines according to claim 1, characterized in that... The diameter of the upper stopper plate (3) is greater than the inner diameter of the bottle mouth, and the diameter of the lower stopper plate (5) is smaller than the inner diameter of the bottle mouth.

3. The negative pressure sealing bottle for pig farm vaccines according to claim 1, characterized in that... The bottle stopper plate (3) is made of plastic, copper, stainless steel or aluminum alloy, and has a thickness of 1-2 mm.

4. The negative pressure sealing bottle for pig farm vaccines according to claim 1, characterized in that... The lower stopper plate (5) is made of plastic, copper, stainless steel or aluminum alloy, and has a thickness of 1-2 mm.

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