A method for continuous crystallization of azoxystrobin

Abstract

The application discloses a kind of azoxystrobin continuous crystallization method, belong to pesticide fungicide technical field.It includes the following steps: first crystallizer, second crystallizer, third crystallizer, fourth crystallizer head-to-tail sequentially interconnect, and from top to bottom are set, the crystal slurry in the crystallizer utilizes height difference self-flow discharge;First, the concentration is 25-30% mass concentration of butyl acetate solution containing azoxystrobin is carried out to crystal operation;After the crystal of butyl acetate solution containing azoxystrobin is precipitated, butyl acetate solution containing azoxystrobin is added to first crystallizer, temperature control is at 53-57 ℃ temperature, stays for a certain time;Then the crystal slurry is overflowed or pumped into second crystallizer, third crystallizer, fourth crystallizer in sequence and is cooled and crystallized, the crystal slurry in fourth crystallizer is overflowed or pumped into transfer tank or centrifuge, and the product is obtained after the crystal slurry is post-treated.The particle size uniformity of the crystalline crystal obtained by the continuous crystallization method provided by the application.

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