A structured light illumination multi-channel tomography system based on polarization interference

By employing polarization interference and phase modulation, the problems of mechanical phase shifting and customized phase masks in existing OS-SIM systems have been solved, enabling fast and flexible optical tomography, improving the system's versatility and imaging efficiency, and expanding the application bands.

CN117607114BActive Publication Date: 2026-06-12SHANGHAI JIAOTONG UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
SHANGHAI JIAOTONG UNIV
Filing Date
2023-11-30
Publication Date
2026-06-12

AI Technical Summary

⚠Technical Problem

In existing OS-SIM systems, the phase shifting of projection systems relies on mechanical movement, while interferometric systems require customized phase masks, and have low optical diffraction efficiency, high cost, and cannot flexibly adjust the structured light fringe period.

⚗Method used

A structured light illumination multichannel tomography system based on polarization interference is adopted. Optical phase shifting is achieved by using a polarized Michelson interference structure and a full-wave liquid crystal variable delay device. Sinusoidal structured light fringes are formed by polarization beam splitting and phase modulation, which reduces mechanical errors and improves the versatility of the system.

🎯Benefits of technology

It enables rapid and flexible adjustment of optical tomography, reduces mechanical errors and device costs, improves the versatility and imaging efficiency of the system, and expands the application band to near-infrared and visible light.

✦ Generated by Eureka AI based on patent content.

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Abstract

Disclosed is a polarization interference-based structured light illumination multi-channel tomographic imaging system, comprising a laser, a beam expander, a polarization interference, a beam shaping, a microscopic imaging, and a phase modulation module; the laser outputs linearly polarized light in a near-infrared band; the beam expander amplifies the beam diameter of the input laser; the polarization interference module divides the incident excitation light into two coherent outgoing lights based on a polarization type Michelson interference structure; the beam shaping module further modulates the diameter and beam spacing of the outgoing light; the microscopic imaging module receives the coherent light beams, is configured as two inclined parallel lights, and interferes at a sample focal plane, so as to form sinusoidal distributed structured light stripes at the sample focal plane, and obtain a fluorescence signal of the sample by structured light illumination excitation; and the phase modulation module can change the phase difference between the two coherent light beams based on the polarization characteristics of a full-wave liquid crystal variable retarder, so as to control the spatial movement of the structured light stripes, thereby realizing the acquisition of images at different phases.
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