Liquid dosing transfer device

CN117861743BActive Publication Date: 2026-08-18SUZHOU LABYRINTH BIOTECH CO LTD
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Patent Information

Application Number
CN202311676025.9
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2023-12-07
Publication Date
2026-08-18
Estimated Expiration
2043-12-07

AI Technical Summary

Technical Problem

[0007]第三方面,液体转移的速度与活塞移动的速度相关,当活塞移动的较快时,压力变化较快,液体移动过程中容易混入空气,进而影响液体的转移量

Benefits of technology

[0030] Compared with the prior art, the beneficial effects of the embodiments of the present invention are as follows: the liquid storage chamber in the liquid storage tube is set in the installation port after sealing. When the piercing head of the piercing member pierces the wall of the liquid storage tube and extends into the liquid storage chamber, the volume of the piercing head increases, causing the air pressure inside the liquid storage chamber to rise. Therefore, the air pressure inside the liquid storage chamber is greater than the external atmospheric pressure. Consequently, the liquid in the liquid storage chamber flows into the second liquid channel under the action of the pressure difference. The outflowing liquid then flows along the second liquid channel and the first liquid channel, eventually flowing into the liquid metering tank. The flow of the liquid stops when the air pressure inside the liquid storage chamber equals the external atmospheric pressure, and at this time, the liquid metering tank is already full of liquid. Therefore, a preset volume of liquid is collected in the liquid metering tank, thereby achieving quantitative transfer of the liquid. It can be seen that the liquid metering transfer device provided by the embodiments of the present invention can achieve quantitative transfer of liquid without the use of a piston, improving the accuracy of quantitative transfer of liquid.

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Abstract

The present application relates to liquid quantitative transfer device, belong to liquid quantitative transfer technical field, liquid quantitative transfer device includes: installation mouth, liquid quantitative tank, liquid quantitative tank has preset volume, first liquid channel, first liquid channel is connected with installation mouth and liquid quantitative tank, liquid storage pipe, liquid storage pipe is detachably arranged in installation mouth, liquid storage pipe is internally provided with the liquid storage cavity that can be sealed, puncture piece, puncture piece is arranged in installation mouth, puncture piece has puncture head and second liquid channel, the entrance of second liquid channel is located on puncture head, the outlet of second liquid channel is communicated with first liquid channel, when the liquid storage cavity is sealed and liquid storage pipe is arranged in installation mouth, puncture head punctures the pipe wall of liquid storage pipe and stretches into the liquid storage cavity, the liquid in liquid storage cavity flows into liquid quantitative tank along second liquid channel and first liquid channel, and liquid quantitative tank is filled with liquid, so as to quantitatively measure liquid.
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Description

Technical Field

[0001] This invention relates to the field of liquid quantitative transfer technology, and in particular to liquid quantitative transfer devices. Background Technology

[0002] Nucleic acid testing requires the use of liquid quantitative transfer technology. Specifically, it involves quantitatively transferring the nucleic acid material extracted from the sample into the nucleic acid reaction system for PCR (Polymerase Chain Reaction) amplification. The purpose of quantitative transfer of nucleic acid material is to ensure successful PCR amplification, as too much or too little nucleic acid material will lead to PCR failure.

[0003] In existing technologies, samples are typically stored in a reservoir within a sample tube, and this reservoir is sealed after sample addition to prevent contact between the sample and outside air. Within the reservoir, nucleic acid substances are extracted by a preservation solution and stored in the sample tube in liquid form. During the transfer of nucleic acid substances from the sample tube, contact with outside air must also be avoided. Therefore, existing technologies often employ a puncture device inserted into the sample tube to transfer the nucleic acid substances. For example, the puncture device may have a liquid channel. When the puncture device is inserted into the reservoir, the inlet of the liquid channel is located within the reservoir, and the outlet is located within a liquid metering tank. By pulling the piston in the liquid metering tank, the air pressure in the liquid metering tank is lower than the air pressure in the sample tube. Under the influence of this pressure difference, the nucleic acid substances in the reservoir flow into the liquid metering tank along the liquid channel.

[0004] However, the method described above, which changes the air pressure by moving the piston, cannot accurately achieve quantitative liquid dispensing for the following reasons:

[0005] Firstly, due to the influence of machining precision, the piston's sealing performance may be poor. In particular, as the piston is continuously pulled in and out, the piston's sealing performance will inevitably decrease, and the sealing performance directly affects the pressure difference, which in turn affects the amount of liquid transferred.

[0006] Secondly, the amount of liquid entering the liquid metering tank depends on the distance the piston moves. Once the distance the piston moves deviates from the specified value, the amount of liquid will change accordingly.

[0007] Thirdly, the speed of liquid transfer is related to the speed of piston movement. When the piston moves faster, the pressure changes more rapidly, and air is more likely to be mixed in during the liquid transfer process, which in turn affects the amount of liquid transferred. Summary of the Invention

[0008] The purpose of this invention is to provide a liquid quantitative transfer device to improve the accuracy of liquid quantitative transfer.

[0009] To achieve the above objectives, embodiments of the present invention provide a liquid quantitative transfer device, comprising:

[0010] Installation port;

[0011] Liquid metering tank;

[0012] A first liquid channel, wherein the first liquid channel connects the mounting port and the liquid metering tank;

[0013] A liquid storage tube, which is detachably disposed in the mounting port, and has a sealable liquid storage chamber inside the liquid storage tube;

[0014] A puncture device is disposed in the installation port, the puncture device having a puncture head and a second liquid channel, the inlet of the second liquid channel being located on the puncture head, and the outlet of the second liquid channel communicating with the first liquid channel;

[0015] When the liquid storage chamber is sealed and the liquid storage tube is placed in the installation port, the puncture head can pierce the wall of the liquid storage tube and extend into the liquid storage chamber so that the liquid in the liquid storage chamber flows into the liquid metering tank along the second liquid channel and the first liquid channel.

[0016] In some embodiments, the volume of the puncture member extending into the reservoir is the volume of liquid flowing out of the reservoir.

[0017] In some embodiments, when the puncture member punctures the wall of the reservoir tube, the connection between the puncture member and the reservoir tube is sealed.

[0018] In some embodiments, the wall of the liquid storage tube is provided with a puncture channel extending toward the height direction of the liquid storage cavity, the puncture member has a puncture portion that can extend into the puncture channel, the puncture head is located at the end of the puncture portion, the puncture portion is adapted to the puncture channel, and after the puncture head extends into the puncture channel, the puncture portion seals the puncture channel.

[0019] In some embodiments, a sealing ring is provided on the puncture site, and when the puncture head punctures the wall of the fluid storage tube, the sealing ring is sealed to the puncture channel; and / or

[0020] After the puncture part is inserted into the puncture channel, the puncture part and the puncture channel are press-fitted together.

[0021] In some embodiments, the wall of the liquid storage tube is provided with a fragile area, and the puncture head is used to puncture the fragile area.

[0022] In some embodiments, the wall thickness of the reservoir tube corresponding to the vulnerable area is less than the wall thickness at other locations on the reservoir tube; and / or

[0023] The fragile area is higher than the bottom wall of the reservoir tube. Within the reservoir, the fragile area divides the reservoir into a lower chamber (lower in height) and an upper chamber (higher in height). If the fragile area breaks, the liquid in the upper chamber exits the reservoir, while the liquid in the lower chamber remains within the lower chamber; and / or

[0024] The wall of the liquid storage tube is provided with a puncture channel extending toward the liquid storage cavity, and the puncture member is at least partially able to extend into the puncture channel, with the vulnerable area located within the puncture channel; and / or

[0025] The puncture channel is located at the edge of the bottom wall of the reservoir tube.

[0026] In some embodiments, the puncture element is detachably disposed in the mounting port.

[0027] In some embodiments, the volume of the puncture member extending into the liquid storage cavity is greater than the sum of the volume of the first liquid channel, the volume of the second liquid channel, and the volume of the liquid metering tank, causing liquid to overflow from the liquid metering tank.

[0028] In some embodiments, the liquid metering transfer device further includes:

[0029] An overflow trough is located on one side of the liquid metering tank, and liquid overflowing from the liquid metering tank flows into the overflow trough.

[0030] Compared with the prior art, the beneficial effects of the embodiments of the present invention are as follows: the liquid storage chamber in the liquid storage tube is set in the installation port after sealing. When the piercing head of the piercing member pierces the wall of the liquid storage tube and extends into the liquid storage chamber, the volume of the piercing head increases, causing the air pressure inside the liquid storage chamber to rise. Therefore, the air pressure inside the liquid storage chamber is greater than the external atmospheric pressure. Consequently, the liquid in the liquid storage chamber flows into the second liquid channel under the action of the pressure difference. The outflowing liquid then flows along the second liquid channel and the first liquid channel, eventually flowing into the liquid metering tank. The flow of the liquid stops when the air pressure inside the liquid storage chamber equals the external atmospheric pressure, and at this time, the liquid metering tank is already full of liquid. Therefore, a preset volume of liquid is collected in the liquid metering tank, thereby achieving quantitative transfer of the liquid. It can be seen that the liquid metering transfer device provided by the embodiments of the present invention can achieve quantitative transfer of liquid without the use of a piston, improving the accuracy of quantitative transfer of liquid. Attached Figure Description

[0031] Figure 1This is a schematic diagram of a liquid quantitative transfer device provided in an embodiment of the present invention.

[0032] Figure 2 An exploded view of the liquid quantitative transfer device provided in an embodiment of the present invention from one perspective.

[0033] Figure 3 This is a schematic diagram of the bottom of the liquid storage tube provided in an embodiment of the present invention.

[0034] Figure 4 for Figure 3 Cross-sectional view at point AA.

[0035] Figure 5 for Figure 4 A schematic diagram of a fragile area on a liquid storage tube after it has been damaged.

[0036] Figure 6 A cross-sectional view showing the swab head positioned inside the reservoir tube.

[0037] Figure 7 This is a schematic diagram of the puncture device provided in an embodiment of the present invention.

[0038] Figure 8 for Figure 7 Cross-sectional view at point BB.

[0039] Figure 9 This is a schematic diagram of the puncture device and the fluid storage tube before and after puncture, provided in an embodiment of the present invention.

[0040] Figure 10 This is a schematic diagram of the side of the outer casing provided in an embodiment of the present invention.

[0041] Figure 11 A perspective view of the outer casing provided in an embodiment of the present invention.

[0042] Figure 12 This is a schematic diagram of the upper part of the liquid metering seat provided in an embodiment of the present invention.

[0043] Figure 13 This is a schematic diagram of the lower part of the liquid metering seat provided in an embodiment of the present invention.

[0044] Figure 14 This is a cross-sectional view of the liquid metering seat and the outer casing provided in an embodiment of the present invention, wherein the liquid metering seat is in a first position.

[0045] Figure 15 This is a cross-sectional view of the liquid metering seat and the outer casing provided in an embodiment of the present invention, wherein the liquid metering seat is in a second position.

[0046] In the picture:

[0047] 1. Outer shell; 11. Mounting port; 12. Mounting groove; 13. First liquid channel; 14. Displacement channel; 15. Second positioning post;

[0048] 2. Liquid metering seat; 21. Liquid metering tank; 22. Liquid inlet; 23. Overflow tank; 24. First annular groove; 25. First positioning post; 26. Positioning groove;

[0049] 3. Liquid reservoir tube; 31. Bottom wall; 32. Side wall; 321. Outer wall; 322. Inner wall; 33. Liquid reservoir cavity; 331. Lower chamber; 332. Upper chamber; 34. Puncture passage; 341. Opening; 35. Connecting wall; 36. Vulnerable area; 361. Central part; 362. Edge part; 37. Tube cap;

[0050] 4. Puncture element; 41. Puncture section; 411. Puncture head; 42. Mounting base; 43. Second fluid channel; 44. Second annular groove;

[0051] 5. Elastic elements;

[0052] 6. End caps;

[0053] 7. Swab head. Detailed Implementation

[0054] The technical solution of the present invention will be further described below with reference to the accompanying drawings and specific embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and not intended to limit it. Furthermore, it should be noted that, for ease of description, only the parts relevant to the present invention are shown in the accompanying drawings, not all of them.

[0055] This invention defines certain directional terms. Unless otherwise stated, the directional terms used, such as "up," "down," "left," "right," "inner," and "outer," are used for ease of understanding and therefore do not constitute a limitation on the scope of protection of this invention.

[0056] In this invention, unless otherwise explicitly specified and limited, "above" or "below" the second feature can include direct contact between the first and second features, or contact between the first and second features through another feature between them. Furthermore, "above," "over," and "on top" of the second feature includes the first feature directly above or diagonally above the second feature, or simply indicates that the first feature is at a higher horizontal level than the second feature. "Below," "below," and "under" the second feature includes the first feature directly below or diagonally below the second feature, or simply indicates that the first feature is at a lower horizontal level than the second feature.

[0057] In the description of this invention, unless otherwise explicitly specified and limited, the terms "connected," "linked," and "fixed" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components. Those skilled in the art can understand the specific meaning of the above terms in this invention based on the specific circumstances.

[0058] Figure 1 A schematic diagram of the liquid quantitative transfer device provided in this embodiment is shown. Figure 2 An exploded view of the liquid metering transfer device provided in this embodiment is shown. Figure 1 and Figure 2 As shown, the liquid metering transfer device includes a housing 1, a liquid metering seat 2, a puncture device 4, and a liquid storage tube 3. Figure 2 From the perspective shown in the outer casing 1, the right side of the outer casing 1 has an installation port 11, and the left side of the outer casing 1 has a transversely extending rightward displacement channel 14. The liquid storage tube 3 and the puncture member 4 are both located within the installation port 11, and the liquid metering seat 2 is located within the displacement channel 14. The liquid metering seat 2 is provided with a liquid metering groove 21. The outer casing 1 is also provided with a first liquid channel 13 (see...). Figure 11 The inlet of the first liquid channel 13 is located in the installation port 11, and the outlet of the first liquid channel 13 is connected to the liquid metering tank 21.

[0059] When using the liquid metering transfer device of this embodiment, the liquid storage tube 3 and the puncture member 4 need to be placed in the installation port 11, and the liquid storage tube 3 and the puncture member 4 are squeezed against each other (for example, the liquid storage tube 3 is moved toward the puncture member 4), so that the puncture member 4 punctures the tube wall of the liquid storage tube 3. The liquid storage chamber 33 inside the liquid storage tube 3 is connected to the first liquid channel 13 on the outer shell 1 through the second liquid channel 43 provided on the puncture member 4. Then, the liquid in the liquid storage chamber 33 can flow through the second liquid channel 43 and the first liquid channel 13 to enter the liquid metering tank 21. The liquid metering tank 21 has a preset volume. When the liquid metering tank 21 is filled with liquid, it means that a predetermined amount of liquid has been collected in the liquid metering tank 21, that is, the quantitative transfer of liquid is realized, and a certain amount of liquid in the liquid storage chamber 33 is transferred into the liquid metering tank 21.

[0060] It is understood that the positions of the mounting port 11 and the shifting channel 14 on the housing 1 are merely examples. In other embodiments, the positions of the mounting port 11 and the shifting channel 14 can be adjusted as needed. For example, the mounting port 11 may be located at... Figure 2 The shift channel 14 is located on the left or middle position of the outer shell 1, etc. Figure 2 The right side, front side, or rear side of the inner shell 1, etc.

[0061] The term "installation port 11" refers to the location on the outer shell 1 used for installing the puncture member 4 and the liquid storage tube 3. Any location that allows the puncture member 4 and the liquid storage tube 3 to be installed on the outer shell 1 is acceptable; the shape of the installation port 11 is not limited in this embodiment. Furthermore, it should be noted that although the puncture member 4 and the outer shell 1 can be detached from each other in this embodiment, in other embodiments, the puncture member 4 may be fixed to the outer shell 1 and cannot be separated from it. For example, the puncture member 4 and the outer shell 1 may be integrally molded, especially by injection molding.

[0062] Furthermore, the shifting channel 14 is not essential for achieving the function of quantitative liquid transfer. The purpose of setting the shifting channel 14 in this embodiment is to allow the liquid metering seat 2 to be moved after a predetermined amount of liquid has been collected in the liquid metering tank 21, so that the liquid metering tank 21 and the first liquid channel 13 are misaligned. The specific misalignment method will be described in detail later. In other embodiments, the purpose of quantitative liquid transfer can still be achieved even if the outer shell 1 does not have the shifting channel 14. In other embodiments, the liquid metering seat 2 can be fixed to the outer shell 1, so that it cannot move relative to the outer shell 1, or even be directly integrally formed with the outer shell 1. However, at least during the process of quantitative liquid transfer, the liquid metering tank 21 needs to be connected to the first liquid channel 13 so that when the puncture member 4 punctures the liquid storage tube 3, the liquid in the liquid storage chamber 33 can flow into the liquid metering tank 21.

[0063] The following describes the specific structures of the storage tube 3, the puncture device 4, the outer shell 1, and the liquid metering tank 21 in sequence, according to the direction in which the liquid flows from the storage chamber 33 into the liquid metering tank 21.

[0064] Figure 3 A schematic diagram of the bottom of the liquid storage tube 3 provided in this embodiment is shown. Figure 4 It shows Figure 3 Cross-sectional view at point AA. (Combined with...) Figure 3 and Figure 4As shown, the liquid storage tube 3 includes a tube body and a tube cap 37. The tube body is a hollow circular tube, thus forming a longitudinally spaced liquid storage cavity 33 inside the tube body. An opening 341 communicating with the liquid storage cavity 33 is provided at the upper part of the tube body, allowing liquid and sample to enter the liquid storage cavity 33. The tube cap 37 is located at the top of the tube body, closing the opening 341. When the tube cap 37 closes the opening 341, the liquid storage cavity 33 is sealed. Sealing means that external atmosphere cannot enter the liquid storage cavity 33, and similarly, gas inside the liquid storage cavity 33 cannot enter the atmosphere. Therefore, when a sample enters the liquid storage cavity 33, the tube cap 37 can be used to seal the liquid storage cavity 33, preventing the sample from contacting the outside air. Furthermore, once the tube cap 37 seals the liquid storage cavity 33, the gas pressure inside the liquid storage cavity 33 remains essentially unchanged because the volume occupied by the liquid and sample in the liquid storage cavity 33 remains essentially constant.

[0065] It should be noted that although the liquid storage chamber 33 is sealed by the cap 37 in this embodiment, in other embodiments, the liquid storage chamber 33 can also be sealed by providing an additional sealing element. For example, the cross-section of the sealing element can be adapted to the cross-section of the liquid storage chamber 33. After the sealing element is installed in the liquid storage chamber 33, the outer wall 321 of the sealing element is tightly connected to the inner wall of the liquid storage chamber 33, thereby achieving the sealing of the liquid storage chamber 33. As an example, the sealing element can be a sealing plug.

[0066] Of course, it is feasible to attach the seal to the tube cap 37, so that when the tube cap 37 is installed on the tube body, the seal will seal the liquid storage chamber 33. Understandably, the seal can also be installed separately from the tube cap 37.

[0067] like Figure 3 As shown, the tube body includes a bottom wall 31 and a side wall 32. The bottom wall 31 is located at the bottom of the tube body and is used to define the bottom of the liquid storage cavity 33. The side wall 32 is connected to the bottom wall 31. The side wall 32 is closed in the circumferential direction and extends upward toward the bottom wall 31, so that the tube body presents a tubular shape as a whole. The side wall 32 defines the side of the liquid storage cavity 33. The top of the side wall 32 forms an opening 341. The tube cap 37 covers the top of the side wall 32 to close the liquid storage cavity 33.

[0068] like Figure 3 As shown, a puncture channel 34 extending toward the liquid storage chamber 33 is provided on the bottom wall 31. In this embodiment, the puncture channel 34 extends longitudinally upward from the bottom wall 31, but in other embodiments, the puncture channel 34 may also be inclined.

[0069] like Figure 4As shown, the so-called puncture channel 34 is formed by the side wall 32. Specifically, the side wall 32 includes an outer wall 321 and an inner wall 322. The outer wall 321 serves as the outer surface of the tube body, and the inner wall 322 is located inside the outer wall 321. The two ends of the inner wall 322 in the circumferential direction are connected to the outer wall 321. The inner wall 322 and the outer wall 321 are spaced apart, so the channel formed between the inner wall 322 and the outer wall 321 is the puncture channel 34.

[0070] like Figure 4 As shown, the inner end of the puncture channel 34 ( Figure 4 A connecting wall 35 is provided at the upper middle part of the puncture channel 34, which separates the puncture channel 34 from the fluid storage chamber 33. When the connecting wall 35 is intact, the fluid storage chamber 33 and the puncture channel 34 are not connected, so the liquid in the fluid storage chamber 33 cannot enter the puncture channel 34. It should be noted that the connecting wall 35 can also be located in the middle of the puncture channel 34 or at any other location.

[0071] In addition, the connecting wall 35 is provided with a fragile area 36. The fragile area 36 is an area that can break when subjected to a certain pressure. Commonly, the fragile area 36 can be achieved by reducing the wall thickness, but it is not limited to this. The fragile area 36 can also be made of easily broken materials, such as glass.

[0072] When the puncture member 4 is inserted into the puncture channel 34 and comes into contact with the connecting wall 35, the fragile area 36 is subjected to pressure from the puncture member 4. When the pressure reaches a certain value, the fragile area 36 will break, thereby forming an opening 341 in the puncture channel 34 that connects the liquid storage chamber 33 and the puncture channel 34. The liquid in the liquid storage chamber 33 can flow out from the liquid storage chamber 33 and flow into the second liquid channel 43 on the puncture member 4.

[0073] like Figure 4 As shown, in this embodiment, the fragile area 36 is located at the edge of the connecting wall 35. The fragile area 36 includes a central portion 361 and an edge portion 362. The edge portion 362 is located at the edge of the central portion 361 and is connected to the wall of the puncture channel 34. The wall thickness of the edge portion 362 is less than the thickness of the central portion 361, making the strength of the edge portion 362 less than that of the central portion 361. Therefore, when the fragile area 36 is subjected to pressure, the edge portion 362 cracks first, and eventually the entire connecting wall 35 falls off, thereby forming an opening 341 (see...). Figure 5 ).

[0074] It should be noted that the vulnerable area 36 can also be located in other positions of the connecting wall 35, such as the central position of the connection. In this case, when the vulnerable area 36 is damaged, the connecting wall 35 will not fall off completely, but a part of it will still remain connected to the wall of the puncture channel 34.

[0075] like Figure 4 As shown, in this embodiment, the connecting wall 35 is positioned higher than the bottom wall 31, creating a height difference between them. The liquid storage chamber 33 is divided into a lower chamber 331 below the connecting wall 35 and an upper chamber 332 above it. When the fragile area 36 on the connecting wall 35 breaks, only the liquid in the upper chamber 332 can flow out, while the liquid in the lower chamber 331 remains inside. This arrangement is intended to prevent the discharge of residues, impurities, and other substances that may be present in the sample. These substances have a relatively high density and will therefore be closer to the bottom wall 31, thus residing in the lower chamber 331, preventing their discharge when the fragile area 36 of the connecting wall 35 breaks.

[0076] Of course, in other embodiments, the connecting wall 35 may also be flush with the bottom wall 31. In this case, the puncture channel 34 may not be provided, and the connecting wall 35 may be part of the bottom wall 31, that is, the vulnerable area 36 is located on the bottom wall 31.

[0077] It should be noted that it is advantageous to set up a puncture channel 34 and place the connecting wall 35 inside the puncture channel 34, because when the shape of the puncture member 4 is adapted to the puncture channel 34, the puncture channel 34 can be sealed. That is to say, when the puncture member 4 punctures the vulnerable area 36, ​​the outside air cannot enter the liquid storage chamber 33 through the gap between the puncture channel 34 and the puncture member 4. Therefore, at the moment the vulnerable area 36 is punctured, the liquid storage chamber 33 is still sealed, thereby ensuring that the liquid in the liquid storage chamber 33 will not come into contact with the outside air.

[0078] Since the liquid storage chamber 33 is sealed, once the puncture member 4 is inserted into the liquid storage chamber 33, the sum of the volumes of liquid and solid in the liquid storage chamber 33 increases, thereby reducing the space occupied by gas, which causes the gas pressure in the liquid storage chamber 33 to rise. Under the action of pressure difference, the liquid in the liquid storage chamber 33 will flow into the second liquid channel 43.

[0079] If the seal between the puncture channel 34 and the puncture member 4 is good enough, the volume of the puncture member 4 extending into the liquid storage chamber 33 will be equal to the volume of liquid flowing out of the liquid storage chamber 33. Based on this principle, the amount of liquid flowing out of the liquid storage chamber 33 can be controlled more precisely. For example, the volume of the puncture member 4 extending into the liquid storage chamber 33 can be determined based on the sum of the volumes of the liquid metering tank 21, the first liquid channel 13, and the second liquid channel 43. When the volume of the puncture member 4 extending into the liquid storage chamber 33 equals the sum of these three volumes, the liquid metering tank 21 is exactly filled with liquid, thus achieving quantitative liquid transfer. Of course, the volume of the puncture member 4 extending into the liquid storage chamber 33 can be slightly larger to ensure that some liquid in the liquid metering tank 21 overflows, thus enabling more precise measurement of the liquid volume.

[0080] like Figure 4 As shown, in this embodiment, the puncture channel 34 is located at the edge of the bottom wall 31, thus the lower chamber 331 adjacent to the puncture channel 34 has a larger radial width to accommodate the swab head 7 (see...). Figure 6 By placing the puncture channel 34 at the edge of the bottom wall 31, the swab head 7 can still be compatible without increasing the diameter and / or length of the tube body. Of course, this embodiment does not exclude placing the puncture channel 34 at other locations on the bottom wall 31, as long as the volume of the tube body can ensure that the swab head 7 can be placed in the liquid storage chamber 33.

[0081] Figure 7 A perspective view of the puncture device 4 provided in this embodiment is shown. Figure 8 It shows Figure 7 Cross-sectional view at point BB. (See diagram below.) Figure 7 and Figure 8 As shown, the puncture device 4 includes a puncture part 41 and a mounting base 42. The mounting base 42 can be installed into the mounting port 11. The puncture part 41 is located on the top of the mounting base 42, so that the puncture part 41 faces upward towards the mounting port 11. In this way, when the liquid storage tube 3 is installed downward into the mounting port 11, the puncture channel 34 at the bottom of the liquid storage tube 3 can be easily aligned with the puncture part 41, and the vulnerable area 36 can be easily punctured by applying downward pressure to the liquid storage tube 3.

[0082] like Figure 2 As shown, an installation slot 12 is provided in the installation port 11. The shape of the installation slot 12 is adapted to the shape of the mounting base 42, so that when the mounting base 42 is installed in the installation slot 12, the piercing member 4 can be securely installed in the installation port 11.

[0083] like Figure 7 and 8As shown, the top of the puncture section 41 is the puncture head 411, and the inlet of the second liquid channel 43 is located on the puncture head 411. Once the puncture head 411 enters the liquid storage chamber 33, it means that the liquid in the liquid storage chamber 33 can enter the second liquid channel 43. The outlet of the second liquid channel 43 is located at the bottom of the puncture member 4, thereby communicating with the inlet of the first liquid channel 13 in the mounting groove 12. It should be noted that in other embodiments, the outlet position of the second liquid channel 43 can be adjusted according to actual needs. For example, the outlet of the second liquid channel 43 can also be located on the side of the puncture member 4.

[0084] like Figure 7 and Figure 8 As shown, in this embodiment, a second annular groove 44 is provided at the middle position of the puncture member 4. A sealing ring (not shown) is installed on the second annular groove 44. In this embodiment, when the puncture head 411 extends into the puncture channel 34, the sealing ring is tightly connected to the puncture channel 34, thereby sealing the connection between the puncture member 4 and the puncture channel 34. Of course, in other embodiments, a sealing ring may not be provided, and the shape of the puncture part 41 may be slightly larger than that of the puncture channel 34, so that after the puncture part 41 extends into the puncture channel 34, they are squeezed together to achieve a seal.

[0085] Figure 9 The diagram shows the puncture device 4 and the fluid reservoir 3 before and after puncture, as provided in this embodiment. Figure 9 As shown, the puncture procedure is as follows:

[0086] Before puncture, the puncture element 4 is generally located in the mounting port 11 and remains relatively stationary with respect to the outer casing 1;

[0087] When puncture is required, insert the reservoir tube 3 into the installation port 11 and align the puncture channel 34 at the bottom of the reservoir tube 3 with the puncture part 41.

[0088] Next, move the liquid storage tube 3 downward so that the puncture part 41 extends into the puncture channel 34;

[0089] As the liquid storage tube 3 continues to move downwards, the sealing ring on the puncture component 4 forms a sealing structure with the puncture channel 34.

[0090] Continue moving the reservoir tube 3 downwards until the puncture head 411 at the top of the puncture piece 4 abuts against the connecting wall 35;

[0091] Continue moving the liquid storage tube 3 downwards, the piercing head 411 pierces the vulnerable area 36 on the connecting wall 35, thereby entering the liquid storage cavity 33 and connecting the liquid storage cavity 33 with the second liquid channel 43.

[0092] Figure 10 A side view of the housing 1 provided in this embodiment is shown. Figure 11 A perspective view of the housing 1 provided in this embodiment is shown, and Figure 10 and Figure 11 The internal structure of the outer casing 1 is shown in dashed lines. For example... Figure 10 and Figure 11 As shown, the first liquid channel 13 is disposed inside the housing 1, with its inlet located in the mounting port 11 and its outlet located within the displacement channel 14. More specifically, in this embodiment, the inlet of the first liquid channel 13 is oriented upwards to facilitate direct connection with the outlet of the second liquid channel 43 in the puncture member 4. The outlet of the first liquid channel 13 is located on the lower surface of the displacement channel 14 to facilitate direct communication with the liquid metering tank 21 on the liquid metering seat 2. This design allows the liquid to enter the liquid metering tank 21 slowly from the bottom, preventing liquid from dripping downwards into the liquid metering tank 21 and causing liquid spillage and loss.

[0093] Figure 12 A schematic diagram of the upper part of the liquid metering seat 2 provided in this embodiment is shown. Figure 13 A schematic diagram of the bottom of the liquid metering seat 2 is shown. Figure 12 and Figure 13 As shown, a liquid metering seat 2 is provided with a liquid metering tank 21. The bottom of the liquid metering tank 21 is provided with a liquid inlet 22. The liquid inlet 22 can be directly connected to the outlet of the first liquid channel 13. In this way, the liquid enters the liquid metering tank 21 from the liquid inlet 22 without causing liquid splashing. Instead, the liquid metering tank 21 is slowly filled from bottom to top, ensuring that there is no loss of liquid entering the liquid metering tank 21 unless it overflows from the top of the liquid metering tank 21. This indicates that the liquid in the liquid metering tank 21 has reached the required volume.

[0094] like Figure 12 As shown, the liquid metering seat 2 is also provided with an overflow groove 23. The overflow groove 23 is located on one side of the liquid metering tank 21. When the liquid overflows from the liquid metering tank 21, it flows into the overflow groove 23. Therefore, it can be determined whether the liquid metering tank 21 is full by observing whether there is liquid in the overflow groove 23.

[0095] As mentioned above, a displacement channel 14 is provided in the outer casing 1, and the liquid metering seat 2 is located within the displacement channel 14. In this embodiment, the liquid metering seat 2 can move within the displacement channel 14, thereby having a first position and a second position. Specifically, as... Figure 14 As shown, the liquid metering seat 2 is in the first position at this time. It can be clearly observed that the inlet 22 is directly connected to the outlet of the first liquid channel 13, and the liquid can flow into the liquid metering tank 21 through the first liquid channel 13. Figure 15As shown, the liquid metering seat 2 is in the second position at this time. It can be clearly observed that the liquid inlet 22 is misaligned with the outlet of the first liquid channel 13, and the liquid cannot enter the liquid metering tank 21. When the liquid overflows from the liquid metering tank 21, the liquid metering seat 2 can be moved from the first position to the second position.

[0096] In this embodiment, the outer end of the shift channel 14 ( Figure 14 An end cap 6 is provided at the left end of the liquid metering seat 2, which confines the liquid metering seat 2 within the shift channel 14 and prevents it from falling out of the outer end of the shift channel 14. Specifically, the end cap 6 has a blocking portion extending toward the shift channel 14. The presence of the blocking portion properly seals the outer end of the shift channel 14, so that the liquid metering seat 2, whose shape is adapted to the shift channel 14, cannot leave the shift channel 14.

[0097] The end cap 6 is provided with a through hole, through which an external operating mechanism can move the liquid metering seat 2, thereby allowing the liquid metering seat 2 to move back and forth between the first position and the second position.

[0098] like Figure 14 As shown, an elastic element 5 (e.g., a spring) can also be provided between the liquid metering seat 2 and the outer casing 1, so that the liquid metering seat 2 can be in the second position in the initial state. When it is necessary to transfer the liquid, the push rod in the operating mechanism can be extended into the displacement channel 14 through the through hole of the end cover 6, and the liquid metering seat 2 can be pushed to the first position by the push rod. After the push rod leaves the displacement channel 14, the liquid metering seat 2 returns to the second position under the elastic force of the elastic element 5.

[0099] To facilitate the fixing of the elastic element 5, a first positioning post 25 can be set on the liquid metering seat 2, and a second positioning post 15 can be set on the outer shell 1. One end of the elastic element 5 is fitted on the first positioning post 25, and the other end of the elastic element 5 is fitted on the second positioning post 15.

[0100] In addition, a positioning groove 26 can be opened on the outer periphery of the first positioning post 25 so that the first positioning post 25 is located in the positioning groove 26, thereby reducing the length of the first positioning post 25 extending beyond the liquid metering seat 2, and making the liquid metering seat 2 miniaturized.

[0101] The foregoing description of embodiments of the present invention, through which those skilled in the art are able to implement or use the present invention, will be readily apparent to those skilled in the art. Various modifications to these embodiments will be readily apparent to those skilled in the art. The general principles defined herein may be implemented in other embodiments without departing from the spirit or scope of the invention. Therefore, the present invention is not to be limited to the embodiments shown herein, but is to be accorded the widest scope consistent with the principles and novelty disclosed herein.

Claims

1. A liquid quantitative transfer device, comprising: Installation port (11); Liquid metering tank (21); The first liquid channel (13) connects the mounting port (11) and the liquid metering tank (21). The liquid storage tube (3) is detachably disposed in the installation port (11). The liquid storage tube (3) has a sealable liquid storage cavity (33) inside. The wall of the liquid storage tube (3) has a puncture channel (34) extending toward the height direction of the liquid storage cavity (33). A puncture member (4) is disposed in the mounting port (11). The puncture member (4) has a puncture head (411) and a second liquid channel (43). The inlet of the second liquid channel (43) is located on the puncture head (411), and the outlet of the second liquid channel (43) is connected to the first liquid channel (13). The puncture member (4) has a puncture part (41) that can extend into the puncture channel (34). The puncture head (411) is located at the end of the puncture part (41). The puncture part (41) is adapted to the puncture channel (34). After the puncture head (411) extends into the puncture channel (34), the puncture part (41) seals the puncture channel (34). When the liquid storage chamber (33) is sealed and the liquid storage tube (3) is disposed in the mounting port (11), the puncture head (411) can puncture the wall of the liquid storage tube (3) and extend into the liquid storage chamber (33) so that the liquid in the liquid storage chamber (33) flows into the liquid metering tank (21) along the second liquid channel (43) and the first liquid channel (13). When the puncture member (4) punctures the wall of the liquid storage tube (3), the connection between the puncture member (4) and the liquid storage tube (3) is sealed. The volume of the puncture member (4) extending into the liquid storage chamber (33) is the volume of liquid flowing out of the liquid storage chamber (33). The wall of the liquid storage tube (3) is provided with a fragile area (36), which is located in the puncture channel (34). The puncture head (411) is used to puncture the fragile area (36). The fragile area (36) is higher than the bottom wall (31) of the liquid storage tube (3). The fragile area (36) divides the liquid storage cavity (33) into a lower chamber (331) with a height lower than the fragile area (36) and an upper chamber (332) with a height higher than the fragile area (36). After the fragile area (36) is damaged, the liquid in the upper chamber (332) leaves the liquid storage cavity (33), and the liquid in the lower chamber (331) remains in the lower chamber (331).

2. The liquid dosing transfer device of claim 1, wherein, A sealing ring is provided on the puncture section (41). When the puncture head (411) punctures the wall of the liquid storage tube (3), the sealing ring is sealed to the puncture channel (34); and / or After the puncture part (41) extends into the puncture channel (34), the puncture part (41) and the puncture channel (34) are press-fitted.

3. The liquid quantitative transfer device according to claim 1, wherein, The wall thickness of the liquid storage tube (3) corresponding to the location of the fragile area (36) is less than the wall thickness at other locations on the wall of the liquid storage tube (3); and / or The puncture channel (34) is located at the edge of the bottom wall (31) of the reservoir tube (3).

4. The liquid quantitative transfer device according to claim 1, wherein, The puncture member (4) is detachably disposed in the mounting port (11).

5. The liquid metering transfer device according to any one of claims 1 to 4, wherein, The volume of the puncture device (4) extending into the liquid storage cavity (33) is greater than the sum of the volume of the first liquid channel (13), the volume of the second liquid channel (43), and the volume of the liquid metering tank (21), causing the liquid to overflow from the liquid metering tank (21).

6. The liquid metering transfer device according to claim 5, wherein, The liquid quantitative transfer device further includes: Overflow tank (23) is located on one side of liquid metering tank (21), and liquid overflowing from liquid metering tank (21) flows into overflow tank (23).

Citation Information

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