A Maikang ointment patch and a patch making method thereof

By preparing the Maikang plaster, a combination of traditional Chinese medicines such as Scutellaria baicalensis, clove, turtle shell, Panax notoginseng, and cinnamon twig was used to solve the treatment problem of phlebitis, especially indurated thrombophlebitis, and achieved significant swelling reduction and pain relief effects.

CN118416126BActive Publication Date: 2026-07-07QUANZHOU ZHENGGU HOSPITAL

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
QUANZHOU ZHENGGU HOSPITAL
Filing Date
2024-05-10
Publication Date
2026-07-07

AI Technical Summary

Technical Problem

There is a lack of effective treatments for phlebitis, especially indurated thrombophlebitis or grade 3 and 4 phlebitis, in the current technology.

Method used

Using Chinese medicinal materials such as Scutellaria baicalensis, clove, turtle shell, Panax notoginseng, and cinnamon twig, the raw materials are processed, ground, extracted and mixed to make Maikang plaster, which is used to relieve the symptoms of phlebitis.

Benefits of technology

Through the efficacy of the combination of traditional Chinese medicine, it achieves the effects of softening and dispersing nodules, reducing swelling and relieving pain in phlebitis, significantly reducing the grade of phlebitis, and curing grade 3 and 4 phlebitis.

✦ Generated by Eureka AI based on patent content.

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Abstract

The application discloses a pulse Kang ointment patch, which has the functions of harmonizing qi and blood, softening and resolving hard masses, and eliminating swelling and relieving pain, and is used for hard knot thrombus type phlebitis or grade III and IV phlebitis; the pulse Kang ointment patch is prepared from the following traditional Chinese medicinal raw materials: Huangqi, mother clove, Biejia, Sanqi, Guizhi and auxiliary materials; a pulse Kang ointment patch preparation method comprises the following steps: steps 1, weighing appropriate amount of the traditional Chinese medicinal raw materials for preparing the pulse Kang ointment patch; steps 2, treating the weighed traditional Chinese medicinal raw materials for preparing the pulse Kang ointment patch; steps 3, grinding the treated traditional Chinese medicinal raw materials for preparing the pulse Kang ointment patch into powder; steps 4, extracting medicinal oil from the ground traditional Chinese medicinal raw material powder for preparing the pulse Kang ointment patch; and steps 5, uniformly mixing the medicinal oil and the auxiliary materials to prepare the pulse Kang ointment.
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Description

Technical Field

[0001] This invention relates to the field of PulseKang plaster technology, and in particular to a PulseKang plaster and its manufacturing method. Background Technology

[0002] Phlebitis refers to acute aseptic inflammation of veins. Due to stimulation of the vessel wall by various factors, the vessel wall becomes inflamed, resulting in local pain, redness, heat, and edema. In severe cases, the vein may show cord-like or even induration-like inflammatory changes. Clinical manifestations are as follows: Grade 0: Asymptomatic; Grade 1: Redness at the infusion site with or without pain; Grade 2: Pain at the infusion site with redness and / or edema; Grade 3: Pain at the infusion site with redness and / or edema, and palpable cord-like venous structures; Grade 4: Pain at the infusion site with redness and / or cord-like structures, and palpable cord-like venous structures >1 inch (2.5 cm) in length, with or without purulent discharge. This paper proposes a patch called "Maikang Ointment" and its preparation method to treat and relieve indurated thrombophlebitis or grade 3 and 4 phlebitis. Summary of the Invention

[0003] The purpose of this invention is to address the shortcomings of the prior art as described in the background section, and to propose a pulse ointment patch and its manufacturing method.

[0004] To achieve the above objectives, the present invention adopts the following technical solution:

[0005] A type of Maikang plaster includes the following traditional Chinese medicine raw materials for making Maikang plaster: Scutellaria baicalensis, clove, turtle shell, Panax notoginseng, cinnamon twig and excipients.

[0006] A method for manufacturing a PulseKang plaster includes the following steps:

[0007] Step 1: Weigh out an appropriate amount of the Chinese herbal raw materials for making the Maikang plaster.

[0008] Step 2: Take the prepared Chinese herbal raw materials for making Maikang plaster and process them symmetrically;

[0009] Step 3: Grind the processed Chinese herbal raw materials for making Maikang plaster into powder;

[0010] Step 4: Extract medicinal oil from the ground Chinese herbal raw material powder used to make Maikang plaster;

[0011] Step 5: Mix the medicinal oil and excipients evenly to prepare the Pulse Health Ointment.

[0012] As a preferred embodiment of the present invention, in step 1, 20g of Scutellaria baicalensis, 20g of clove, 20g of turtle shell, 15g of Panax notoginseng, and 15g of cinnamon twig are weighed out.

[0013] As a preferred embodiment of the present invention, Steps2-1: Clean the weighed Chinese herbal raw materials for making Maikang plaster;

[0014] Step 2-2: Dry the cleaned Chinese herbal raw materials for making Maikang plaster.

[0015] As a preferred embodiment of the present invention, Steps 2-2-1, cutting the cleaned Chinese herbal raw materials for making the Maikang plaster into slices before drying helps to ensure even drying.

[0016] As a preferred embodiment of the present invention, in Steps 3, the dried, sheet-like Chinese herbal raw materials for making the Maikang plaster are ground into powder in a grinder or a high-speed blender.

[0017] As a preferred embodiment of the present invention, in Steps4, the powdered Chinese herbal raw materials for making the Maikang plaster are poured into an extractor and mixed with vegetable oil. The extractor is then used to extract the medicinal oil and separate the medicinal oil from the precipitate.

[0018] As a preferred embodiment of the present invention, Steps 5-1: The medicinal oil and the precipitate are poured into a concentration pot for concentration treatment. The medicinal oil is concentrated to remove excess water and impurities, and the precipitate is concentrated to form a medicinal mud.

[0019] Step 5-2: Place the concentrated medicinal oil and medicinal mud in a mixer and add excipients, then mix well to prepare the Maikang plaster.

[0020] As a preferred embodiment of the present invention, the patch is placed in a cool, ventilated place, avoiding direct sunlight, to allow for natural aging and maturation, thereby ensuring the quality and efficacy of the patch.

[0021] Compared with the prior art, the beneficial effects of the present invention are as follows:

[0022] In this application: Scutellaria baicalensis clears heat and dries dampness, drains fire and detoxifies; Clove warms the middle and dispels cold, promotes qi and relieves pain; Turtle shell reduces fever and eliminates steaming, softens hardness and dissipates nodules; Panax notoginseng has the effects of promoting blood circulation and removing blood stasis, reducing swelling and relieving pain; Cinnamon twig warms and unblocks the meridians, promotes blood circulation and dispels wind; when prepared with petroleum jelly, the combined effects of these drugs are to harmonize qi and blood, soften hardness and dissipate nodules, reduce swelling and relieve pain, and are used for induration thrombophlebitis or grade III and IV phlebitis. Attached Figure Description

[0023] Figure 1 Implementation Case Statistics Table Detailed Implementation

[0024] The invention will be more readily understood by referring to the following detailed description of preferred embodiments and included examples. Unless otherwise specified, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention pertains. In case of conflict, the definitions in this specification shall prevail.

[0025] As used herein, the terms “prepared from” and “comprising” are synonymous. The terms “comprising,” “including,” “having,” “containing,” or any other variations thereof, as used herein, are intended to cover non-exclusive inclusion. For example, a composition, step, method, article, or apparatus that includes the listed elements is not necessarily limited to those elements, but may include other elements not expressly listed or elements inherent to such composition, step, method, article, or apparatus.

[0026] The conjunction "composed of..." excludes any unspecified elements, steps, or components. If used in a claim, this phrase makes the claim closed, excluding materials other than those described, except for associated conventional impurities. When the phrase "composed of..." appears in a clause of the body of a claim rather than immediately following it, it limits only the elements described in that clause; other elements are not excluded from the claim as a whole.

[0027] When a quantity, concentration, or other value or parameter is expressed as a range, a preferred range, or a range defined by a series of upper and lower preferred values, this should be understood as specifically disclosing all ranges formed by any pair of any upper or preferred value with any lower or preferred value, regardless of whether the range is disclosed individually. For example, when the range “1 to 5” is disclosed, the described range should be interpreted as including the ranges “1 to 4”, “1 to 3”, “1 to 2”, “1 to 2 and 4 to 5”, “1 to 3 and 5”, etc. When numerical ranges are described herein, unless otherwise stated, the range is intended to include its endpoints and all integers and fractions within that range.

[0028] The singular form includes the plural objects of discussion, unless the context clearly indicates otherwise. "Optional" or "any one" means that the matter or event described thereafter may or may not occur, and the description includes both the possibility that the event occurs and the possibility that the event does not occur.

[0029] Approximate terms used in the specification and claims to modify quantities indicate that the invention is not limited to that specific quantity, but also includes acceptable modifications close to that quantity that do not alter the relevant essential function. Correspondingly, the use of "about," "approximately," etc., to modify a numerical value means that the invention is not limited to that precise value. In some instances, approximate terms may correspond to the precision of the instrument used to measure the value. In this application's specification and claims, scope definitions can be combined and / or interchanged, unless otherwise stated, these scopes include all subscopes contained therein.

[0030] Furthermore, the indefinite articles “a” and “an” preceding the elements or components of this invention do not impose any limitation on the quantity requirement (i.e., the number of times) of the elements or components. Therefore, “an” or “a” should be interpreted as including one or at least one, and the singular form of an element or component also includes the plural form, unless the quantity clearly refers to the singular form.

[0031] The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments.

[0032] Example 1

[0033] A type of Maikang plaster includes the following traditional Chinese medicine raw materials for making Maikang plaster: Scutellaria baicalensis, clove, turtle shell, Panax notoginseng, cinnamon twig and excipients.

[0034] Example 2

[0035] A method for manufacturing a PulseKang plaster includes the following steps:

[0036] Step 1: Weigh out an appropriate amount of the Chinese herbal raw materials for making the Maikang plaster.

[0037] Step 2: Take the prepared Chinese herbal raw materials for making Maikang plaster and process them symmetrically;

[0038] Step 3: Grind the processed Chinese herbal raw materials for making Maikang plaster into powder;

[0039] Step 4: Extract medicinal oil from the ground Chinese herbal raw material powder used to make Maikang plaster;

[0040] Step 5: Mix the medicinal oil and excipients evenly to prepare the Pulse Health Ointment.

[0041] Example 3

[0042] A method for manufacturing a PulseKang plaster includes the following steps:

[0043] Step 1: Weigh out the following Chinese herbal raw materials for making the Maikang plaster: 20g of Scutellaria baicalensis, 20g of clove, 20g of turtle shell, 15g of Panax notoginseng, and 15g of cinnamon twig.

[0044] The second step is to clean and slice the weighed Chinese herbal raw materials for making the Maikang plaster.

[0045] The third step is to dry the sliced ​​Chinese herbal raw materials used to make the Maikang plaster.

[0046] The fourth step is to grind the dried, sheet-like Chinese herbal raw materials used to make the Maikang plaster into powder using a grinder or a high-speed blender.

[0047] Step 5: Pour the obtained Chinese herbal raw material powder for making Maikang plaster into the extractor, add vegetable oil and mix well. Use the extractor to extract the medicinal oil and separate the medicinal oil from the precipitate.

[0048] Step 6: Pour the medicinal oil and sediment into a concentration pot for concentration treatment. The medicinal oil is concentrated to remove excess water and impurities, and the sediment is concentrated to form medicinal mud.

[0049] Step 7: Place the concentrated medicinal oil and medicinal mud in a mixer and add excipients, then mix well to prepare the Maikang plaster.

[0050] Step 8: Place the patch in a cool, ventilated place, avoiding direct sunlight, to allow it to age and deteriorate naturally, thus ensuring the quality and effectiveness of the patch.

[0051] The effects of each Chinese herbal raw material are as follows:

[0052] Scutellaria baicalensis: It has the effects of purging excess heat, removing damp heat, stopping bleeding, and calming the fetus. It is mainly used to treat high fever and thirst, lung heat cough, damp heat diarrhea, jaundice, urinary tract infection, vomiting, epistaxis, metrorrhagia, metrorrhagia, red and swollen eyes, threatened abortion, carbuncles and boils. Processing: 1. Scutellaria baicalensis: Remove impurities and residual stems, soak in cold water or briefly soak in boiling water, then slice and sun-dry. Take care to avoid excessive sun exposure and reddening. 2. Wine-processed Scutellaria baicalensis: Spray the slices with rice wine, mix well, stir-fry over low heat, remove and dry. Use 10-15 catties of rice wine for every 100 catties of Scutellaria baicalensis. 3. Stir-fried Scutellaria baicalensis: Stir-fry the slices over low heat until the surface is slightly charred, remove and cool. 4. Charred Scutellaria baicalensis: Stir-fry the slices over high heat until the surface is charred brown and the edges are black, but retain its properties. Spray with water, remove and sun-dry.

[0053] Clove: It has the effects of warming the middle and dispelling cold, regulating qi and relieving pain. It is mainly used to treat sudden heart pain, stomach cold and vomiting, wind-cold toothache, loose teeth, halitosis, cold vulva in women, and inguinal hernia in children. Processing: Harvest the fruit when it is ripe and dry it in the sun.

[0054] Turtle shell: It has the effects of nourishing yin and clearing heat, calming the liver and extinguishing wind, softening hardness and dispersing nodules. It is mainly used to treat fever and bone steaming, yin deficiency and wind stirring, malaria, abdominal masses, amenorrhea and metrorrhagia, and infantile convulsions. Processing: Soak turtle shell in water, remove the skin and flesh, wash it clean, and dry it in the sun. Vinegar turtle shell: First, put clean sand into a pot and heat it. Then add clean turtle shell and stir-fry until the surface is slightly yellow. Take it out and sift out the sand. Soak it briefly in a vinegar basin. Take it out, rinse it with water, and dry it in the sun. For every 100 catties of turtle shell, use 30 catties of vinegar.

[0055] Panax notoginseng: It has the effects of stopping bleeding, dispersing blood stasis, reducing swelling, and relieving pain. It is mainly used to treat hematemesis, hemoptysis, epistaxis, hematochezia, bloody dysentery, metrorrhagia, abdominal masses, postpartum hemorrhage, lochia retention, traumatic blood stasis, external bleeding, and carbuncles and boils. Processing: Dig up the tubers, wash off the soil and place them according to size. Sun-dry or bake at 36-38℃ for 2 to 3 days. When they are about 60% dry, cut off the branch roots, fibrous roots and rhizomes separately, and sun-dry or bake them separately for 2 to 3 days. Rub them or put them in a rotating drum to make them rub against each other. Take them out and sun-dry or bake them again. Repeat this process 4 to 5 times. For the last time, you can add some dragon's beard grass or green beans until the tubers are smooth, round and dry.

[0056] Cinnamon twigs: They have the effects of inducing sweating and relieving muscle tension, warming the meridians and promoting blood circulation. They are mainly used to treat wind-cold syndrome, soreness and pain in the shoulders, back and limbs, chest pain and phlegm retention, amenorrhea and abdominal masses. Preparation: Tender branches are cut in July and August, cut into small sections about 15 to 100 cm long, and dried in the sun.

[0057] Use cases:

[0058] Case 1: Li Xinxin, male, 54 years old. Symptoms: Grade III phlebitis developed in the forearm after long-term intravenous infusion at another hospital. Pain and edema occurred at the injection site, and nodules and cord-like changes were palpable in the vein. After using Maikang ointment once a day for 10 times, the swelling, pain, nodules and cord-like changes in the affected area disappeared. After the medication, the phlebitis grade dropped to grade 0, and he was cured.

[0059] Case 2: Ye Junying, male, 55 years old. Symptoms: Grade III phlebitis after insertion of a 24-gauge indwelling needle in the forearm. Pain and edema occurred at the injection site, and induration and cord-like changes were palpable in the vein. After using Maikang ointment once a day for 7 days, the swelling, pain and induration at the affected site disappeared, and the phlebitis grade dropped to grade 0. He was cured.

[0060] Case 3: Long Luoyang, male, 39 years old. Symptoms: Grade III phlebitis after insertion of a 20-gauge indwelling needle in the forearm. Pain and edema occurred at the injection site, and induration and cord-like changes were palpable in the vein. He used Maikang ointment once a day. After 5 applications, the swelling, pain and induration at the affected site disappeared. After the medication, the phlebitis grade dropped to grade 0, and he was cured.

[0061] The examples described herein are merely illustrative, intended to explain some features of the methods described herein. The appended claims are intended to claim the broadest possible scope, and the embodiments presented herein are merely illustrative of selected implementations based on combinations of all possible embodiments. Therefore, the applicant intends that the appended claims are not limited by the selection of examples illustrating the features of the invention. Some numerical ranges used in the claims also include sub-ranges within them, and variations within these ranges should be interpreted, where possible, as covered by the appended claims.

Claims

1. A pulse-relieving plaster for treating phlebitis, characterized in that, It is composed of the following Chinese herbal raw materials and excipients: 20g of Scutellaria baicalensis, 20g of clove, 20g of turtle shell, 15g of Panax notoginseng, and 15g of cinnamon twig. The excipients are petrolatum or vegetable oil.

2. The method for preparing a pulse-clearing plaster for treating phlebitis according to claim 1, characterized in that, Includes the following steps: Step 1: Weigh out 20g of Scutellaria baicalensis, 20g of clove, 20g of turtle shell, 15g of Panax notoginseng, and 15g of cinnamon twig; Step 2: After cleaning the weighed Chinese medicinal materials, slice them and dry them; Step 3: Grind the dried flake raw materials into powder using a grinder or blender; Step 4: Pour the powder into the extractor, add vegetable oil and mix well to extract the medicinal oil and separate the precipitate; Step 5: Concentrate the medicinal oil to remove impurities, concentrate the precipitate into a medicinal paste, mix the two with the excipients evenly, and prepare the Maikang plaster. Step 6: Place the Pulse Health Plaster in a cool, ventilated place to age.