A kind of reproductive promotion gilt compound feed and its preparation method and application

Abstract

The present invention provides a gilt feed for promoting reproduction, a preparation method and an application thereof, wherein the gilt feed for promoting reproduction comprises 80-110 parts of a base material, 1-2 parts of a calcium salt, 1-3 parts of a functional additive and 1-2 parts of a premix by weight; the functional additive comprises 10-30 parts of a plant extract, 0.01-0.1 parts of punicalagin and 0.01-0.1 parts of calendula officinalis by weight. The gilt feed provided by the present invention can stimulate the rapid maturation of the gilt's reproductive system, remove excess free radicals produced by the body, maintain the balance of the redox system in the body, avoid oxidative stress that damages the gilt's reproductive system, and can also timely initiate the gilt's first estrus, promote estrus in the gilt, and improve the fertility of the gilt.

Description

Technical Field

[0001] The invention belongs to the technical field of feed, and in particular relates to a reproductive promotion gilt compound feed, a preparation method and an application thereof. Background Art

[0002] In pig breeding and production, the breeding of reserve sows occupies an important position and is the basis and key part of the rapid development of the pig herd. Only by improving the reproductive capacity of reserve sows can the reproductive capacity of basic sows be guaranteed and the efficiency of the pig farm can be effectively improved.

[0003] The onset of puberty is an important sign that gilts have acquired reproductive capacity. The timely onset of puberty and good follicular development in gilts can effectively improve the reproductive performance of gilts. The sow reserve period is a process of continuous physical development until sexual maturity. During this stage, the rate of sexual maturity and the onset of puberty are very sensitive to nutritional regulation. The physiological state and nutritional metabolism of the body change significantly, which can easily induce the body to produce excessive free radicals. When the redox system in the gilt loses balance, oxidative stress will occur, and the ovaries of gilts are easily affected by oxidative stress, which will damage the development of pig ovaries and thus affect the onset of puberty in gilts.

[0004] At present, there are common problems in pig farming, such as gilts not coming into estrus or delayed estrus, which seriously affects the breeding efficiency of pig farms. Therefore, it is urgent to develop a gilt feed that promotes reproduction, so as to relieve oxidative stress in gilts, improve the antioxidant capacity of gilts, and start the first estrus of gilts in time. Summary of the invention

[0005] In view of the deficiencies of the prior art, the purpose of the present invention is to provide a reproductive promotion gilt compound feed and its preparation method and application. The gilt compound feed provided by the present invention can stimulate the rapid maturation of the gilt's reproductive system, remove excess free radicals produced by the body, maintain the balance of the body's redox system, avoid oxidative stress that damages the gilt's reproductive system, and can also timely start the gilt's puberty, promote gilt estrus, and improve the fertility of gilts.

[0006] In order to achieve the purpose of the invention, the present invention adopts the following technical solutions:

[0007] In a first aspect, the present invention provides a reproductive gilt compound feed, wherein the reproductive gilt compound feed comprises, by weight, 80-110 parts of a base material, 1-2 parts of a calcium salt, 1-3 parts of a functional additive, and 1-2 parts of a premix;

[0008] The functional additives include 10-30 parts of plant extract, 0.01-0.1 parts of punicalagin, and 0.01-0.1 parts of calendula officinalis by weight.

[0009] The base material may be 80, 90, 100 or 110 parts, the calcium salt may be 1, 1.2, 1.4, 1.6, 1.8 or 2 parts, the functional additive may be 1, 1.5, 2, 2.5 or 3 parts, the premix may be 1, 1.2, 1.4, 1.6, 1.8 or 2 parts, etc.; the plant extract may be 10, 15, 20, 25 or 30 parts. The amount of punicalagin can be 0.01, 0.02, 0.03, 0.04, 0.05, 0.06, 0.07, 0.08, 0.09 or 0.1, etc., the amount of phytosterol can be 0.01, 0.02, 0.03, 0.04, 0.05, 0.06, 0.07, 0.08, 0.09 or 0.1, etc., and other values ​​not listed within the above numerical range are equally applicable.

[0010] By using functional additives, the above-mentioned products can maintain an appropriate growth rate of gilts, maintain an appropriate back fat thickness, stimulate the rapid maturation of the reproductive system of gilts, and eliminate excess free radicals produced by the body, maintain the balance of the body's redox system, avoid oxidative stress that damages the reproductive system of gilts, and can also initiate the first estrus of gilts in a timely manner, promote estrus of gilts, and improve the reproductive capacity of gilts.

[0011] Preferably, the functional additives further include 20-40 parts by weight of wall materials, wherein the wall materials include sodium alginate and / or palmitic acid glyceride.

[0012] Preferably, the base material comprises any one of corn, soybean meal or fish meal, or a combination of at least two of them.

[0013] Preferably, the calcium salt comprises calcium.

[0014] Preferably, the plant extract comprises any one of a Belamcanda chinensis extract, a Plantago asiatica extract or a chamomile extract, or a combination of at least two thereof.

[0015] Preferably, the plant extract is a combination of Belamcanda chinensis extract, Plantago asiatica extract and Chamomile extract.

[0016] Plantago seed extract contains a variety of active ingredients such as polysaccharides, quercetin, flavonoids, phenylethanoid glycosides, volatile oils and alkaloids. It has the effects of anti-oxidative stress, exerting estrogen-like effects, regulating the body's immunity, reducing germ cell apoptosis, and repairing ovarian damage. It can stimulate the maturation of the reproductive system of gilts and initiate the first estrus of gilts in a timely manner.

[0017] Chamomile extract has multiple effects such as anti-inflammatory and antioxidant. It works synergistically with Belamcanda chinensis extract and Plantago seed extract to maintain the balance of the redox system of the gilt's body, stimulate the maturation of the gilt's reproductive system, initiate the gilt's puberty in a timely manner, and promote estrus in the gilt.

[0018] Belamcanda chinensis extract has multiple functions such as anti-inflammatory, antioxidant, antiviral, and hormone regulation. It can relieve the oxidative stress of the body of gilts, increase hormone levels, promote the development of follicles in gilts, and initiate estrus.

[0019] Combretin has anti-inflammatory, anti-oxidative stress, immune regulation and other effects. Adding Combretin to the gilt compound feed of the present invention can prevent the gilt from suffering from oxidative stress damage to the body, thereby affecting the follicle development and further affecting the reproduction of the gilt.

[0020] Punicalagin has anti-inflammatory, anti-oxidative stress, immune regulation and other effects. The addition of paeoniflorin to the gilt compound feed of the present invention can relieve the oxidative stress of the gilt body, improve the hormone level, promote the follicle development of the gilt, and initiate estrus.

[0021] The above functional additives are compounded with plant extracts, punicalagin and phytosterol, and the synergistic effects of Belamcanda chinensis extract, Plantago seed extract and Chamomile extract are used to effectively further improve the effect of the product.

[0022] Preferably, the mass ratio of the Belamcanda chinensis extract, Plantago asiatica extract and chamomile extract is (1-3):(2-4):(3-5), wherein the number of Belamcanda chinensis extract can be 1 part, 1.5 parts, 2 parts, 2.5 parts or 3 parts, the number of Plantago asiatica extract can be 2 parts, 2.5 parts, 3 parts, 3.5 parts or 4 parts, and the number of chamomile extract can be 3 parts, 3.5 parts, 4 parts, 4.5 parts or 5 parts, but are not limited to the values ​​listed above, and other values ​​not listed within the above numerical range are equally applicable.

[0023] Preferably, the premix comprises trace elements and vitamins.

[0024] In a second aspect, the present invention provides a method for preparing the above-mentioned reproductive promotion gilt compound feed, the preparation method comprising the following steps:

[0025] The base material is crushed, and then mixed with calcium salt, functional additives and premixes to obtain the reproductive-promoting gilt compound feed.

[0026] In a third aspect, the present invention also provides the use of the above-mentioned reproductive promotion gilt compound feed in piglet gilt breeding.

[0027] Compared with the prior art, the present invention has the following beneficial effects:

[0028] The present invention provides a reproductive promotion gilt compound feed, which can maintain a suitable growth rate of gilts, maintain a suitable back fat thickness, stimulate the rapid maturation of the reproductive system of gilts, remove excessive free radicals produced by the body, maintain the balance of the redox system in the body, avoid oxidative stress that damages the reproductive system of gilts, and timely initiate the first estrus of gilts, promote estrus of gilts, and improve the reproductive capacity of gilts. DETAILED DESCRIPTION

[0029] In order to further explain the technical means and effects adopted by the present invention, the technical solution of the present invention is further described below in conjunction with the preferred embodiments of the present invention, but the present invention is not limited to the scope of the embodiments.

[0030] In the following examples, the plantago extract was purchased from Shifang Hengruikang Biotechnology Co., Ltd.;

[0031] Belamcanda chinensis extract was purchased from Xi'an Tongze Biotechnology Co., Ltd.;

[0032] Chamomile extract was purchased from Baoji Xuhuang Biotechnology Co., Ltd.;

[0033] Punicalagin was purchased from Munster (Chengdu) Biotechnology Co., Ltd.;

[0034] Cherifoliin was purchased from Chengdu Desit Biotechnology Co., Ltd.

[0035] Preparation Example 1

[0036] This preparation example provides a functional additive, the specific ingredients are as follows (by weight):

[0037] 20 parts of plant extracts (belamcanda chinensis extract, plantain seed extract, chamomile extract, mass ratio 2:3:4), 0.05 parts of punicalagin, 0.05 parts of plantain glycoside, 30 parts of wall materials (sodium alginate, palmitic acid glyceride, mass ratio 1:4).

[0038] Mix the above ingredients.

[0039] Preparation Example 2

[0040] This preparation example provides a functional additive, the specific ingredients are as follows (by weight):

[0041] 10 parts of plant extracts (belamcanda chinensis extract, plantain seed extract, chamomile extract, mass ratio 1:2:3), 0.1 parts of punicalagin, 0.01 parts of plantain glycoside, 20 parts of wall materials (sodium alginate, palmitic acid glyceride, mass ratio 1:4).

[0042] Mix the above ingredients.

[0043] Preparation Example 3

[0044] This preparation example provides a functional additive, the specific ingredients are as follows (by weight):

[0045] 30 parts of plant extracts (belamcanda chinensis extract, plantain seed extract, chamomile extract, mass ratio 3:4:5), 0.01 parts of punicalagin, 0.1 parts of plantain glycoside, 40 parts of wall materials (sodium alginate, palmitic acid glyceride, mass ratio 1:4).

[0046] Mix the above ingredients.

[0047] Preparation Example 4

[0048] This preparation example provides a functional additive, and the specific ingredients are the same as those in Preparation Example 1, except that the Belamcanda chinensis extract is not added and the reduced portion is proportionally distributed to Plantago asiatica extract and chamomile extract.

[0049] Preparation Example 5

[0050] This preparation example provides a functional additive. The specific ingredients are the same as those in Preparation Example 1, except that the plantago seed extract is not added and the reduced portion is proportionally distributed to the Belamcanda chinensis extract and the chamomile extract.

[0051] Preparation Example 6

[0052] This preparation example provides a functional additive. The specific ingredients are the same as those in Preparation Example 1, except that chamomile extract is not added and the reduced portion is proportionally distributed to plantago seed extract and belamcanda chinensis extract.

[0053] Preparation Example 7

[0054] This preparation example provides a functional additive, and the specific ingredients are consistent with those in Preparation Example 1 except that no plant extract is added and the reduced portion is proportionally distributed to punicalagin and calendula officinalis.

[0055] Preparation Example 8

[0056] This preparation example provides a functional additive, and the specific ingredients are consistent with those in Preparation Example 1 except that punicalagin is not added and the reduced part is proportionally distributed to plant extracts and calendula officinalis.

[0057] Preparation Example 9

[0058] This preparation example provides a functional additive, and the specific ingredients are consistent with those in Preparation Example 1 except that phytosalidroside is not added and the reduced part is proportionally distributed to punicalagin and plant extract.

[0059] Example 1

[0060] This embodiment provides a reproductive promotion gilt compound feed, the specific ingredients (by weight) are as follows:

[0061] 70 parts of corn, 17 parts of soybean meal, 1.5 parts of calcium bicarbonate, 1.5 parts of fish meal, 2 parts of the functional additive provided in Preparation Example 1, and 1.5 parts of premix.

[0062] The ingredients of the premix are as follows: each Kg of feed contains: FeSO4·7H2O, 300 mg; CuSO4·5H2O, 10 mg; MnSO4·H2O, 50 mg; ZnSO4·7H2O, 500 mg; KI, 0.2 mg; NaSeO3, 0.5 mg; VB1, 1.5 mg; VB2, 10 mg; VK, 10 mg; VD3, 1000 IU; VB12, 30 μg; VE, 30 IU; VA, 10000 IU; choline chloride, 100 mg.

[0063] Preparation method: grind corn and soybean meal, mix them evenly with fish meal, functional additives, calcium bicarbonate and premix to obtain the product.

[0064] Embodiment 2-9

[0065] Examples 2-9 respectively provide a reproductive promotion gilt compound feed, and the specific ingredients are the same as those of Example 1 except that the functional additives provided in Preparation Example 1 are replaced with equal amounts of the functional additives provided in Preparation Examples 2-9.

[0066] The preparation method is similar to that of Example 1.

[0067] Effect test:

[0068] The experiment selected 90 non-estrus gilts with a body weight (100kg±5) and similar age (180±5), and randomly divided them into 10 treatment groups. The control group used conventional gilt feed, and the experimental groups were fed with the reproductive gilt compound feed provided in Examples 1-9. Each treatment had nine replicates, with one pig in each replicate, and the experiment lasted for 35 days.

[0069] Weight and backfat thickness

[0070] The weight of the gilts was measured at the beginning and end of the experiment, and the backfat thickness at point P2 was measured using a backfat meter. Based on the weight and backfat thickness data before and after the experiment, the average daily weight gain and backfat thickness difference were calculated. The results are as follows:

[0071]

[0072]

[0073] Detection and identification of puberty

[0074] During the experiment, the estrus of the sows was checked twice a day, morning and evening. The first day of estrus was recorded when the vulva of the sows was red and swollen, and thin mucus flowed out. After the experiment, the experimental pig group was continuously followed (until the gilts were 230 days old, and the gilts that had not yet started the first estrus were considered as anestrus sows), and the subsequent estrus status was recorded until the gilts of this batch were 230 days old, and the estrus rate was calculated (estrus rate (%) = 100% × number of gilts in estrus / number of gilts). The results are as follows:

[0075] Group Estrus rate during the test period (%) Total estrus rate (%) Control group 22.22％ 33.33％ Example 1 77.78％ 100.00％ Example 2 66.67％ 88.89％ Example 3 77.78％ 88.89％ Example 4 55.56％ 77.78％ Example 5 44.44％ 66.67％ Example 6 44.44％ 66.67％ Example 7 33.33％ 44.44％ Example 8 44.44％ 55.56％ Example 9 33.33％ 55.56％

[0076] Serum progesterone level measurement

[0077] On the morning of the 36th day of the experiment, before feeding, 10 mL of anterior vena cava blood was collected from each gilt, left to stand for 10 min, centrifuged at 3500 r / min for 10 min, and the serum was separated and stored at -20 degrees for later use.

[0078] Sow serum samples were taken and the progesterone content was determined using enzyme-linked immunosorbent assay (ELISA). The kit was purchased from Nanjing Jiancheng Biological Co., Ltd. and the determination method was strictly followed according to the instructions. The results are as follows:

[0079]

[0080]

[0081] Serum antioxidant index

[0082] The serum catalase, glutathione peroxidase (GSH-Px) activity, malondialdehyde (MDA) content, and total antioxidant capacity (T-AOC) in the above serum samples were detected using a kit (Nanjing Jiancheng Bioengineering Institute). The results are as follows:

[0083]

[0084] From the above results, it can be found that the product provided by the present invention can effectively maintain the appropriate growth rate of gilts, maintain the appropriate back fat thickness, stimulate the rapid maturation of the reproductive system of gilts, and can remove excess free radicals produced by the body, maintain the balance of the redox system in the body, avoid oxidative stress that damages the reproductive system of gilts, and can also timely initiate the first estrus of gilts, promote estrus of gilts, and improve the reproductive capacity of gilts; by comparing Examples 1 and 4-9, it can be found that the present invention can effectively further improve the effect of the product by compounding plant extracts, punicalagin and phytophthora indica, and using the synergistic effect of Belamcanda chinensis extract, Plantago seed extract and chamomile extract.

[0085] The applicant declares that the present invention uses the above-mentioned embodiments to illustrate the reproductive promotion gilt compound feed of the present invention and its preparation method and application, but the present invention is not limited to the above-mentioned embodiments, that is, it does not mean that the present invention must rely on the above-mentioned embodiments to be implemented. Those skilled in the art should understand that any improvement of the present invention, equivalent replacement of the raw materials of the product of the present invention, addition of auxiliary ingredients, selection of specific methods, etc., all fall within the protection scope and disclosure scope of the present invention.

[0086] The preferred embodiments of the present invention are described in detail above. However, the present invention is not limited to the specific details in the above embodiments. Within the technical concept of the present invention, a variety of simple modifications can be made to the technical solution of the present invention, and these simple modifications all belong to the protection scope of the present invention.

[0087] It should also be noted that the various specific technical features described in the above specific embodiments can be combined in any suitable manner without contradiction. In order to avoid unnecessary repetition, the present invention will not further describe various possible combinations.

Claims

1. A compound feed for promoting reproduction of gilts, characterized in that: The reproductive promotion gilt compound feed comprises, by weight, 80-110 parts of base material, 1-2 parts of calcium salt, 1-3 parts of functional additives and 1-2 parts of premix; The functional additives include 10-30 parts of plant extract, 0.01-0.1 parts of punicalagin, and 0.01-0.1 parts of calendula officinalis by weight; The plant extract is a combination of a Belamcanda chinensis extract, a Plantago asiatica extract and a Chamomile chamomile extract, and the mass ratio of the Belamcanda chinensis extract, the Plantago asiatica extract and the Chamomile chamomile extract is (1-3):(2-4):(3-5).

2. The reproductive promotion gilt compound feed according to claim 1, characterized in that: The base material comprises any one of corn, soybean meal or fish meal, or a combination of at least two of them.

3. The reproductive promotion gilt compound feed according to claim 1 or 2, characterized in that: The calcium salt includes calcium bicarbonate.

4. The reproductive promotion gilt compound feed according to claim 1, characterized in that: The functional additives also include 20-40 parts of wall materials by weight.

5. The reproductive promotion gilt compound feed according to claim 4, characterized in that: The wall material comprises sodium alginate and / or palmitic acid glyceride.

6. The reproductive promotion gilt compound feed according to claim 1, characterized in that: The premix includes trace elements and vitamins.

7. A method for preparing a reproductive promotion feed for gilts according to any one of claims 1 to 6, characterized in that: The preparation method comprises the following steps: The base material is crushed, and then mixed with calcium salt, functional additives and premixes to obtain the reproductive-promoting gilt compound feed.

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