Tobacco antiviral protein gene nbsrc2 and its application in inhibiting tobacco virus infection
By overexpressing the tobacco antiviral protein gene NbSRC2 in tobacco, the environmental threats posed by chemical pesticides and the problems of viral diseases have been solved, achieving effective inhibition of TMV, CMV and PVY viruses and providing an environmentally friendly method for disease control.
CN119192310BActive Publication Date: 2026-06-16WEIFANG VOCATIONAL COLLEGE +1
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- WEIFANG VOCATIONAL COLLEGE
- Filing Date
- 2024-09-23
- Publication Date
- 2026-06-16
AI Technical Summary
⚠Technical Problem
Existing technologies are insufficient to effectively control tobacco viral diseases, the use of chemical pesticides poses a threat to the environment and organisms, and viral diseases cause huge economic losses.
⚗Method used
The tobacco antiviral protein gene NbSRC2 was used to construct an expression vector to overexpress it in tobacco, thereby inhibiting the infection of tobacco common mosaic virus (TMV), tobacco cucumber mosaic virus (CMV), and potato virus Y (PVY).
🎯Benefits of technology
The NbSRC2 protein can significantly inhibit viral infection, reduce viral expression in tobacco, reduce disease symptoms, provide an alternative to biopesticides, and reduce environmental pollution.
✦ Generated by Eureka AI based on patent content.
Smart Images
Figure CN119192310B_ABST
Abstract
The application discloses a tobacco antiviral protein gene NbSRC2 and application thereof in inhibiting plant virus infection of tobacco, and belongs to the technical field of biology and molecular biology. The amino acid sequence of the tobacco antiviral protein gene NbSRC2 is shown as SEQ ID NO: 2, and the nucleic acid sequence is shown as SEQ ID NO: 1. The application silences NbSRC2 through a VIGS technology, and the differences in virus coat protein CP mRNA, virus coat protein CP and virus infection symptoms all show that silencing NbSRC2 up-regulates the sensitivity of Nicotiana benthamiana to TMV infection and promotes the infection of the virus. Overexpression of NbSRC2 inhibits TMV infection. This shows that NbSRC2 can inhibit the infection of a plant virus, is a potential antiviral gene on tobacco, and can be applied as a potential antiviral protein, and further enriches the category of antiviral genes.
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