Valve stent and valve prosthesis

Abstract

The application relates to the technical field of medical devices, and provides a valve stent and a valve prosthesis, wherein the valve stent comprises a support main body for connecting artificial valve leaves and at least one abutting support group connected with the support main body, the abutting support group comprises a first abutting support and a second abutting support for abutting the same native valve leaf, and the first abutting support comprises an extension section located at the radial outer side of the support main body, having a gap in the radial direction with the support main body and having an overlapping area in the axial direction. Through the technical scheme, the elastic force of the valve stent can be improved, the valve stent is more easily attached to the native valve ring, and the problem of paravalvular leakage is reduced.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of medical devices, in particular to a valve stent and a valve prosthesis. BACKGROUND

[0002] Currently, the main transcatheter mitral valve replacement valve disclosed in the prior art or on the market is a cutting stent made of nickel-titanium alloy as a skeleton, and an artificial valve leaflet and a perivalvular sealing material are combined with the stent by sewing to form an artificial mitral valve.

[0003] Due to the soft texture of the native mitral valve annulus and atrial wall, which constantly changes with the heart pulse and other reasons, and the large left ventricular systolic pressure, the stent after transplantation and positioning is prone to displacement relative to the heart tissue or the stent deforms, resulting in that the stent no longer has good adhesion with the heart tissue. SUMMARY

[0004] The technical problem to be solved by the present application is to provide a valve stent and a prosthesis, which can improve the adhesion of the valve stent to the heart tissue.

[0005] In order to solve the above technical problems, the present application adopts the following technical solutions:

[0006] In a first aspect, the present application provides a valve stent, comprising: a support main body for connecting an artificial valve leaflet and at least one abutment body group connected with the support main body, the abutment body group comprising a first abutment body and a second abutment body for abutting the same native valve leaflet, the first abutment body comprising an extension segment located radially outside the support main body, having a gap in the radial direction with the support main body and having an overlapping area in the axial direction.

[0007] In the implementation process of the above technical solution, the valve stent comprises a support main body for connecting an artificial valve leaflet and at least one abutment body group connected with the support main body, the abutment body group comprises a first abutment body and a second abutment body for abutting the same native valve leaflet, which reduces the influence of the native valve leaflet on the fluid mechanics of the artificial valve leaflet, reduces the influence on the left ventricular outflow tract, and reduces the risk of left ventricular outflow tract obstruction; at the same time, the first abutment body comprises an extension segment located radially outside the support main body, having a gap in the radial direction with the support main body and having an overlapping area in the axial direction, so that the extension segment of the outer periphery of the valve stent can have a deformation space in the direction of the support main body, thus facilitating the absorption of the deformation caused by the heart pulse, thereby improving the stability and adhesion of the support main body. The extension segment has an overlapping area with the support main body in the axial direction, which can increase the adhesion area of the extension segment with the heart tissue, and also increase the elastic force of the extension segment, so that the valve stent is more easily adhered to the heart tissue.

[0008] As an implementation form, the first abutting branch body comprises two first connecting segments connected to the support body respectively, two radial extension segments extending radially from the first connecting segments relative to the support body, the extension segments extending upward from the radial extension segments respectively, and a convex segment connecting the top points of the two extension segments.

[0009] In the implementation process of the above technical solution, the first abutting branch body comprises two first connecting segments connected to the support body respectively, two radial extension segments extending radially from the first connecting segments relative to the support body, the extension segments extending upward from the radial extension segments respectively, and a convex segment connecting the top points of the two extension segments, so that the first abutting branch body forms a frame structure, thereby improving the clamping force of the clamped native leaflet and the stability of the structure. Meanwhile, since the first abutting branch body comprises the radial extension segments, gaps are formed between the extension segments and the first connecting segments, and further gaps are formed between the extension segments and the support body, thereby increasing the elastic force of the valve stent.

[0010] As an implementation form, the top point of the extension segment exceeds the middle part of the support body.

[0011] In the implementation process of the above technical solution, the top point of the extension segment exceeds the middle part of the support body, so that the length of the extension segment in the axial direction is increased as much as possible, which can improve the fitting area with the heart tissue and also improve the elastic force of the extension segment.

[0012] As an implementation form, the top point of the extension segment exceeds the convex segment for abutting against one side of the native leaflet.

[0013] In the implementation process of the above technical solution, since the convex segment needs to abut against one side of the native leaflet, the convex segment needs to have a certain height in the axial direction, and the top point of the extension segment exceeds the convex segment for abutting against one side of the native leaflet, so that the length of the extension segment in the axial direction is increased, and the elastic support force of the extension segment on the convex segment is also increased, so that the first abutting branch body is easily fitted with the heart tissue.

[0014] As an implementation form, the convex segment comprises two convex sub-segments extending obliquely to each other and a horizontal first abutting segment, two ends of the first abutting segment are connected to the two convex sub-segments respectively, one end of the extension segment is connected to the convex sub-segment, and the other end is connected to the radial extension segment, or;

[0015] The convex segment comprises two convex sub-segments extending obliquely to each other, one end of the extension segment is connected to the convex sub-segment, and the other end is connected to the radial extension segment.

[0016] In the implementation process of the above technical solution, the protruding section includes two mutually inclined extending protruding subsections and a horizontal first abutting section, the horizontally arranged first abutting section can increase the abutting area of the protruding section and the native leaflet, so as to improve the clamping force of the first abutting branch, or;

[0017] The protruding section includes two mutually inclined extending protruding subsections, one end of the extending section is connected with the protruding subsection, and the other end is connected with the radially extending section, so that the two protruding subsections form an abutting point, which cooperates with the second abutting branch to clamp the same native leaflet, and also reduces the recovery resistance of the valve stent.

[0018] As an implementation manner, the second abutting branch extends towards the radial outer side of the support main body and includes two second connecting sections extending towards each other and a horizontal second abutting section, two ends of the second abutting section are connected with the two second connecting sections respectively, or the second abutting branch extends towards the radial outer side of the support main body and includes two second connecting sections extending towards each other, one end of the two second connecting sections is connected with each other, and the other end is connected with the support main body respectively.

[0019] In the implementation process of the above technical solution, the second abutting branch extends towards the radial outer side of the support main body and includes two second connecting sections extending towards each other and a horizontal second abutting section, two ends of the second abutting section are connected with the two second connecting sections respectively, by arranging the horizontal second abutting section, the contact area with the native leaflet can be increased, so as to improve the stability between the second abutting branch and the native leaflet; or the second abutting branch includes two second connecting sections extending towards each other, one end of the two second connecting sections is connected with each other, and the other end is connected with the support main body respectively, so that the two second connecting sections form an abutting point, which cooperates with the first abutting branch to clamp the same native leaflet, and also reduces the recovery resistance of the valve stent.

[0020] As an implementation manner, the second abutting branch extends towards the radial outer side of the support main body and includes two second connecting sections extending towards each other and a horizontal second abutting section, two ends of the second abutting section are connected with the two second connecting sections respectively, or the second abutting branch extends towards the radial outer side of the support main body and includes two second connecting sections extending towards each other, one end of the two second connecting sections is connected with each other, and the other end is connected with the support main body respectively.

[0021] In the implementation process of the above technical solution, the second abutting branch body extends outward from the support main body by a distance greater than the distance by which the first abutting branch body extends outward from the support main body, so that the second abutting branch body can support one side of the native leaflet, facilitating the clamping of the native leaflet by the first abutting branch body and the second abutting branch body. At the same time, since the protruding sub-segment is inclined outward in the radial direction relative to the extending segment, the outward extension distance of the second abutting branch body is greater than the distance of the first abutting branch body, so that the second abutting segment of the second abutting branch body or the meeting position of the two second connecting segments can correspond to the first abutting segment of the first abutting branch body or the meeting position of the two protruding sub-segments, and the native leaflet can be clamped better.

[0022] As an implementation form, the support main body comprises a plurality of support units, and the plurality of support units enclose a channel for blood flow; wherein each of the support units comprises two first support bodies for connecting different artificial leaflets, respectively, and the vertical projections of the plurality of first support bodies are on the same radius circle.

[0023] In the implementation process of the above technical solution, the support main body comprises a plurality of support units, and the plurality of support units enclose a channel for blood flow; wherein each of the support units comprises two first support bodies for connecting different artificial leaflets, respectively, and the vertical projections of the plurality of first support bodies are on the same radius circle, so that the plurality of support units can be conveniently connected with the artificial leaflets, and the opening of the artificial leaflet can be enlarged.

[0024] As an implementation form, the valve stent comprises a plurality of second support bodies respectively connecting two first support bodies in the same support unit, and a space formed between the two first support bodies in the same support unit and the second support body can be covered by a sealing layer; the second support body is located in the upstream direction of the first support body; the two first support bodies in the same support unit extend in the downstream direction from both ends of the second support body, respectively, and the two first support bodies meet and connect.

[0025] In the implementation process of the above technical scheme, the valve stent comprises a plurality of second support bodies respectively connecting two first support bodies in the same support unit, and a space between the two first support bodies and the second support body in the same support unit is covered by the sealing layer, so that when the sealing layer is connected with the second support body and the two first support bodies respectively, the sealing space of the sealing layer is covered, thereby the sealing property of the perivalvular part of the valve stent can be enhanced, and the perivalvular leakage problem can be reduced; the second support body is located in the upstream direction of the first support body, so that the second support body can be anchored on the atrial side to improve the stability between the valve stent and the heart tissue; the two first support bodies in the same support unit extend from both ends of the second support body to the downstream direction respectively, and the two first support bodies are connected by converging, so that the two first support bodies in the same support unit gradually narrow toward the downstream direction, facilitating the connection with the artificial valve leaflet.

[0026] As an implementation manner, the second support body comprises two transition connection sections and an anchoring section, two ends of the anchoring section are connected with one end of the two transition connection sections respectively, the other end of the transition connection section is connected with the first support body, and the transition connection section and the anchoring section are arranged at an angle; the anchoring section comprises a protruding section protruding outward along the radial direction of the support main body and used for connecting with a delivery device.

[0027] In the implementation process of the above technical scheme, the second support body comprises two transition connection sections and an anchoring section, two ends of the anchoring section are connected with one end of the two transition connection sections respectively, the other end of the transition connection section is connected with the first support body, so that the two transition connection sections and the anchoring section surround a frame structure, can perform an anchoring function on the atrial side, and improve the stability between the valve stent and the heart tissue; meanwhile, the transition connection section and the anchoring section are arranged at an angle, so that the valve stent is more easily attached to the atrial side; and the anchoring section further comprises a protruding section protruding outward along the radial direction of the support main body and used for connecting with a delivery device, which can realize the anchoring function and the connection with the delivery device, so that the delivery device can conveniently deliver the valve stent.

[0028] As an implementation manner, one end of the two first support bodies in the same support unit is connected with one end of the two second abutting support bodies through a first connecting piece; one end of the two first abutting support bodies is connected through a first connecting piece.

[0029] In the implementation process of the above technical scheme, the first connecting piece can connect the two first support bodies and the two second abutting support bodies in the same support unit, so as to improve the stability of the valve stent; meanwhile, the first connecting piece can also connect the two first abutting support bodies, so as to realize the compactness of the structure of the valve stent.

[0030] In a second aspect, the application provides a valve stent, comprising: a support body for connecting artificial valve leaflets, and a plurality of abutment body groups connected to the support body, each abutment body group comprising a first abutment body and a second abutment body for abutting the same native valve leaflet, a containing space being formed between the plurality of abutment body groups, and the support body being located in the containing space, the first abutment body having a deformation space in the radial direction.

[0031] In the implementation process of the above technical solution, the valve stent comprises a support body for connecting artificial valve leaflets and a plurality of abutment body groups connected to the support body, each abutment body group comprising a first abutment body and a second abutment body for abutting the same native valve leaflet, a containing space being formed between the plurality of abutment body groups, and the support body being located in the containing space, the first abutment body having a deformation space in the radial direction.

[0032] As an implementation form, the abutment body groups extend radially outward toward the support body, and the support body is in contact with the heart tissue through the abutment body groups.

[0033] In the implementation process of the above technical solution, the abutment body groups extend radially outward toward the support body, and the support body is in contact with the heart tissue through the abutment body groups, so that the support body is not directly in contact with the heart tissue, and the abutment body groups serve to space the heart tissue from the support body, thereby reducing the influence of the native valve leaflet on the artificial valve leaflet on the support body through the abutment body groups, and improving the service life of the valve stent.

[0034] In a third aspect, the application provides a valve prosthesis, comprising the valve stent provided in the first aspect or the second aspect, artificial valve leaflets connected to the first support bodies, and a sealing layer connected to the two first support bodies and the second support body in the same support unit.

[0035] In the implementation process of the above technical solution, the artificial valve leaflets are tricuspid valves, which replace the opening and closing actions of the native mitral valve leaflets, and the sealing layer is connected to the two first support bodies and the second support body in the same support unit, which can be used to seal the gaps of the valve stent to enhance the sealing performance of the valve stent. BRIEF DESCRIPTION OF DRAWINGS

[0036] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings needed to be used in the embodiments of the present application will be briefly introduced as follows. It should be understood that the following drawings only show some of the embodiments of the present application, and therefore should not be considered as limiting the scope. For those skilled in the art, other related drawings can also be obtained without creative labor on the basis of these drawings.

[0037] Figure 1 Structure diagram of a valve prosthesis provided by the embodiments of the present application;

[0038] Figure 2 Structure diagram of a valve prosthesis provided by the embodiments of the present application from different perspectives;

[0039] Figure 3 Structure diagram of a valve prosthesis provided by different embodiments of the present application;

[0040] Figure 4 Structure diagram of a valve prosthesis provided by the embodiments of the present application from another perspective;

[0041] Figure 5 Structure diagram of a valve prosthesis implanted in a heart tissue provided by the embodiments of the present application.

[0042] Figure: 1 - support body; 11 - first support body; 12 - second support body; 121 - transition connecting section; 122 - anchoring section; 1221 - protruding section; 2 - abutment support group; 21 - first abutment support; 211 - protruding section; 2111 - protruding sub-section; 212 - extending section; 213 - first abutment section; 214 - first connecting section; 215 - radially extending section; 22 - second abutment support; 221 - second connecting section; 222 - second abutment section; 3 - first connecting member; 4 - second connecting member; 5 - artificial valve leaflet; 6 - sealing layer. DETAILED DESCRIPTION

[0043] The technical solutions in the embodiments of the present application will be described in detail below with reference to the drawings in the embodiments of the present application.

[0044] It should be noted that: similar reference numerals and letters represent similar items in the following drawings, and therefore, once an item is defined in one drawing, it does not need to be further defined and explained in subsequent drawings. Meanwhile, in the description of the present application, the terms "first", "second", etc. are only used for distinguishing description, and cannot be understood as indicating or implying relative importance.

[0045] In a first aspect, the embodiments of the present application provide a valve stent, which is simple in structure, uses a nickel-titanium wire as a raw material, can reduce production cost and improve safety, and has good elastic deformation force, can better fit the heart tissue, and reduce the problem of paravalvular leakage.

[0046] As shown in Figure 1 and 5 , the valve stent comprises a support body 1 for connecting an artificial valve leaflet 5 and at least one abutting body group 2 connected with the support body 1, the abutting body group 2 comprises a first abutting body 21 and a second abutting body 22 for abutting the same native valve leaflet, by arranging the abutting body group 2, the influence of the native valve leaflet on the fluid mechanics of the artificial valve leaflet 5 can be reduced, and the influence on the left ventricular outflow tract is also reduced, and the risk of left ventricular outflow tract obstruction is reduced; the first abutting body 21 comprises an extension segment 212 located on the radial outer side of the support body 1, having a gap in the radial direction with the support body 1 and having an overlapping area in the axial direction, so that the extension segment 212 on the outer periphery of the valve stent can have a deformation space in the direction of the support body 1, increasing the elastic force of the whole valve stent, when the extension segment 212 on the periphery is subjected to a force in the radial direction, the extension segment 212 can deform inward or outward in the radial direction, thus being beneficial to absorbing the deformation caused by the heart pulse, thereby improving the stability and fit of the support body 1. The extension segment 212 has an overlapping area with the support body 1 in the axial direction, which can increase the fit area of the extension segment 212 with the heart tissue, so that the valve stent is more easily fit with the heart tissue, and the problem of paravalvular leakage is reduced.

[0047] Optionally, the extension segment 212 has an overlapping area with the support body 1 in the axial direction, which means that the extension segment 212 extends in the axial direction of the valve stent, and the projection of the extension segment 212 in the direction of the support body 1 towards the support body 1 will make the projection of the part of the extension segment 212 projected on the support body 1 partially overlap with the support body 1.

[0048] Optionally, the valve stent is provided with three abutting body groups 2, so as to clamp the native valve leaflet from multiple directions.

[0049] Optionally, the support body 1 and the abutting body group 2 can use a nickel-titanium wire, which can reduce the production cost of the valve stent yoke and improve the safety of the valve stent compared with the nickel-titanium tube of the prior art.

[0050] Optionally, the first abutting body 21 is used for abutting the inner side of the native valve leaflet, and the second abutting body 22 is used for abutting the outer side of the native valve leaflet.

[0051] As shown in Figure 1As shown, as an embodiment, the first abutting branch 21 comprises two first connecting segments 214 connected with the support body 1 respectively and two radial extension segments 215 radially extended from the first connecting segments 214 relative to the support body 1, the extension segments 212 are extended upward from the radial extension segments 215 respectively, and the convex segment 211 is connected with the top points of the two extension segments 212, so that the first abutting branch 21 forms a frame structure to improve the clamping force of the clamped native leaflet and the stability of the structure; at the same time, since the first abutting branch 21 comprises the radial extension segments 215, the gap is formed between the extension segments 212 and the first connecting segments 214, and further the gap is formed between the extension segments 212 and the support body 1, so that the elastic force of the valve stent is increased.

[0052] As shown in the drawings, Figure 1 As an embodiment, the top point of the extension segment 212 exceeds the middle part of the support body 1, so that the extension segment 212 increases the length in the axial direction as much as possible, which can improve the fitting area with the heart tissue and also improve the elastic force of the extension segment 212.

[0053] As shown in the drawings, Figure 1 As an embodiment, the top point of the extension segment 212 exceeds the convex segment 211 for abutting the side of the native leaflet, since the convex segment 211 needs to abut the side of the native leaflet, the convex segment 211 needs to have a certain height in the axial direction, and the top point of the extension segment 212 exceeds the convex segment 211 for abutting the side of the native leaflet, so that the length of the extension segment 212 in the axial direction is increased, and the elastic support force of the extension segment 212 to the convex segment 211 is also increased, so that the first abutting branch 21 is easily fitted with the heart tissue.

[0054] As shown in the drawings, Figure 3 As an embodiment, the convex segment 211 comprises two convex sub-segments 2111 extending at an angle to each other and a horizontal first abutting segment 213, the two ends of the first abutting segment 213 are connected with the two convex sub-segments 2111 respectively, one end of the extension segment 212 is connected with the convex sub-segment 2111, and the other end is connected with the radial extension segment 215, the horizontally arranged first abutting segment 213 can increase the abutting area of the convex segment 211 with the native leaflet, so as to improve the clamping force of the first abutting branch 21.

[0055] As shown in the drawings, Figure 2 As an embodiment, the convex segment 211 comprises two convex sub-segments 2111 extending at an angle to each other, one end of the extension segment 212 is connected with the convex sub-segment 2111, and the other end is connected with the radial extension segment 215, so that the two convex sub-segments 2111 form an abutting point, which cooperates with the second abutting branch 22 to clamp the same native leaflet, and also reduces the recovery resistance of the valve stent.

[0056] As shown in Figure 1 As an implementation, the second abutting branch 22 extends towards the radial outer side of the support body 1, and includes two second connecting segments 221 extending obliquely towards each other and a horizontal second abutting segment 222, two ends of the second abutting segment 222 are connected with the two second connecting segments 221 respectively. By arranging the horizontal second abutting segment 222, the contact area with the native leaflet can be increased, so as to improve the stability between the second abutting branch 22 and the native leaflet.

[0057] As an implementation, the second abutting branch 22 extends towards the radial outer side of the support body 1, and includes two second connecting segments 221 extending obliquely towards each other and a horizontal second abutting segment 222, two ends of the second abutting segment 222 are connected with the two second connecting segments 221 respectively. By arranging the horizontal second abutting segment 222, the contact area with the native leaflet can be increased, so as to improve the stability between the second abutting branch 22 and the native leaflet.

[0058] As an implementation, the second abutting branch 22 extends towards the radial outer side of the support body 1, and includes two second connecting segments 221 extending obliquely towards each other and a horizontal second abutting segment 222, two ends of the second abutting segment 222 are connected with the two second connecting segments 221 respectively. By arranging the horizontal second abutting segment 222, the contact area with the native leaflet can be increased, so as to improve the stability between the second abutting branch 22 and the native leaflet.

[0059] As an implementation, the support body 1 includes a plurality of support units, and the plurality of support units enclose a channel for blood flow; wherein each support unit includes two first support bodies 11 for connecting different artificial leaflets 5 respectively, and the vertical projections of the plurality of first support bodies 11 are on the same radius circle, so that the plurality of support units can be conveniently connected with the artificial leaflets 5, and the opening of the artificial leaflets 5 is enlarged; and the covering efficiency and yield can also be improved.

[0060] As shown in Figure 1As shown, as an embodiment, the valve stent comprises a plurality of second support bodies 12 respectively connecting two first support bodies 11 in the same support unit, and a space between the two first support bodies 11 and the second support body 12 in the same support unit is covered and connected by the sealing layer 6, so that when the sealing layer 6 is connected with the second support body 12 and the two first support bodies 11 respectively, the space covered by the sealing layer 6 is covered, thereby the sealing of the perivalvular part of the valve stent can be enhanced, and the problem of perivalvular leakage can be reduced; the second support body 12 is located in the upstream direction of the first support body 11, so that the second support body 12 can be anchored on the atrial side to improve the stability between the valve stent and the heart tissue; the two first support bodies 11 in the same support unit extend from both ends of the second support body 12 to the downstream direction respectively, and the two first support bodies 11 are connected at the convergence, so that the two first support bodies 11 in the same support unit gradually narrow toward the downstream direction, facilitating the connection with the artificial valve leaflet 5.

[0061] Optionally, the upstream direction is the blood inflow end.

[0062] As shown in Figure 1 , 2 and 4, as an embodiment, the second support body 12 comprises two transition connection sections 121 and an anchoring section 122, both ends of the anchoring section 122 are connected with one end of the two transition connection sections 121 respectively, and the other end of the transition connection section 121 is connected with the first support body 11, so that the two transition connection sections 121 and the anchoring section 122 form a frame structure, which can perform the anchoring function on the atrial side to improve the stability between the valve stent and the heart tissue; at the same time, the transition connection section 121 and the anchoring section 122 are arranged at an angle, so that the valve stent is more easily attached to the atrial side; and the anchoring section 122 further comprises a protruding section 1221 protruding outward along the radial direction of the support body 1 for connecting with the delivery device, which can realize the anchoring function and the connection with the delivery device on the one hand, and can facilitate the delivery device to deliver the valve stent on the other hand.

[0063] As shown in Figure 2 and 5 , as an embodiment, the valve stent further comprises a plurality of first connecting pieces 3, which can connect the two first support bodies 11 in the same support unit and the two adjacent second abutting support bodies 22, so as to improve the stability of the valve stent; at the same time, the first connecting piece 3 can also connect the two adjacent first abutting support bodies 21, so as to realize the compactness of the structure of the valve stent.

[0064] Optionally, the two first support bodies 11 in the same support unit and the two adjacent second abutting support bodies 22 are arranged in parallel and connected by the first connecting piece 3, so that the valve stent can reduce the radial volume occupied in the contracted state.

[0065] As shown in Figure 2 Optionally, the valve stent comprises a plurality of second connecting members 4, two adjacent first support bodies 11 in two adjacent support units are connected to one side of the second connecting member 4 in parallel; two adjacent second support bodies 12 are connected to the other side of the second connecting member 4 in parallel, which improves the structural compactness of the valve stent, and reduces the occupied volume of the valve stent in the radial direction in the collapsed state of the valve stent, facilitating the delivery device to deliver.

[0066] Optionally, the first abutment support body 21 and the second abutment support body 22 are made of at least one metal wire. When the valve stent is made of one longitudinal material, the valve stent has high integrity and is easy to process. When the valve stent is made of multiple longitudinal materials, the two longitudinal materials connected by riveting pipes can be fixedly connected by riveting or welding. In addition, the connection between the two longitudinal materials can also be fixedly connected by welding or threaded connection.

[0067] As shown in Figure 1 In a second aspect, the application provides a valve stent, which comprises a support body 1 for connecting an artificial valve leaflet and a plurality of abutment support body groups 2 connected to the support body 1, each abutment support body group 2 comprises clamping the same native valve leaflet, reducing the influence of the native valve leaflet on the fluid mechanics of the artificial valve leaflet 5, reducing the influence on the left ventricular outflow tract, reducing the risk of left ventricular outflow tract obstruction; a plurality of abutment support body groups 2 form a containing space, the support body 1 is located in the containing space, so that there is a gap between the support body 1 and the abutment support body group 2, the abutment support body group 2 comprises a first abutment support body 21 and a second abutment support body 22, the first abutment support body 21 has a deformation space in the radial direction, thereby increasing the elasticity of the whole valve stent, making the valve stent more easily conform to the heart tissue and reducing the problem of paravalvular leakage.

[0068] As an embodiment, the abutment support body group 2 extends radially outwardly towards the support body 1, and the support body 1 is in contact with the heart tissue through the abutment support body group 2, so that the support body 1 is not directly in contact with the heart tissue, and the abutment support body group 2 is equivalent to spacing the heart tissue and the support body 1, reducing the influence of the native valve leaflet on the artificial valve leaflet 5 on the support body 1 through the abutment support body group 2, thereby improving the service life of the valve stent.

[0069] As shown in Figure 1 , 4In the third aspect, as shown in FIG. 5, the application provides a valve prosthesis, which comprises the valve stent provided in the first aspect or the second aspect, an artificial valve leaflet 5 connected with the first support body 11, and a sealing layer 6 connected with the two first support bodies 11 and the second support body 12 in the same support unit. The artificial valve leaflet 5 is a three-leafed valve, which replaces the opening and closing actions of the native mitral valve leaflet, and the sealing layer 6 connected with the two first support bodies 11 and the second support body 12 in the same support unit can be used to seal the gap of the valve stent, so as to strengthen the perivalvular sealing.

[0070] Optionally, the artificial valve leaflet 5 can be connected with the first support body 11 in a way of covering film or suturing.

[0071] The above merely provides the embodiments of the application, and is not used to limit the protection scope of the application. For those skilled in the art, the application can have various modifications and changes. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the application should be included in the protection scope of the application.

[0072] The above merely provides the embodiments of the application, and is not used to limit the protection scope of the application. For those skilled in the art, the application can have various modifications and changes. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the application should be included in the protection scope of the application.

[0073] It should be noted that, in the present document, the relative terms such as first and second, etc. are merely used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply that there is any such actual relationship or order between these entities or operations. Moreover, the terms “include”, “contain” or any other variant thereof are intended to cover non-exclusive inclusion, so that the process, method, article or device including a series of elements not only includes those elements, but also includes other elements not explicitly listed or inherent to such process, method, article or device. Without more limitation, the element defined by the statement “including a…” does not exclude the presence of another identical element in the process, method, article or device including the element.

Claims

1. A valve stent, characterized by, Comprise: A support body for connecting artificial valve leaflets and at least one abutment body group connected to the support body, the abutment body group comprising a first abutment body and a second abutment body for abutting the same native valve leaflet, the first abutment body comprising an extension located radially outside the support body, having a gap in the radial direction and an overlapping area in the axial direction with the support body; the extension is used to conform to the heart tissue, the first abutment body is used to abut the inner side of the native valve leaflet, and the second abutment body is used to abut the outer side of the native valve leaflet; The support body comprises a plurality of support units, which surround a channel for blood flow; Wherein each of the support units comprises two first support bodies for connecting different artificial valve leaflets respectively, One end of the two first support bodies in the same support unit is connected to one end of the two second abutment bodies through a first connecting piece; One end of the two first abutment bodies is connected through the first connecting piece.

2. The valve support of claim 1, wherein, The first abutment body comprises two first connecting segments connected to the support body respectively, two radial extension segments extending radially from the first connecting segments relative to the support body, the extension segments extending upward from the radial extension segments respectively, and a protruding segment connecting the apices of the two extension segments.

3. The valve stent of claim 1 or 2, wherein, The apices of the extension segments exceed the middle part of the support body.

4. The valve support of claim 2, wherein, The apices of the extension segments exceed the protruding segment for abutting one side of the native valve leaflet.

5. The valve support of claim 2, wherein, The protruding segment comprises two protruding sub-segments extending obliquely to each other and a horizontal first abutment segment, both ends of the first abutment segment are connected to the two protruding sub-segments respectively, one end of the extension segment is connected to the protruding sub-segment, and the other end is connected to the radial extension segment, or; The protruding segment comprises two protruding sub-segments extending obliquely to each other, one end of the extension segment is connected to the protruding sub-segment, and the other end is connected to the radial extension segment.

6. The valve support of claim 1 or 2, wherein, The second abutment body extends towards the radial outside of the support body, comprising two second connecting segments extending obliquely to each other and a horizontal second abutment segment, both ends of the second abutment segment are connected to the two second connecting segments respectively, or; The second abutment body extends towards the radial outside of the support body, comprising two second connecting segments extending obliquely to each other, one end of the two second connecting segments is connected to each other, and the other end is connected to the support body respectively.

7. The valve support of claim 1 or 2, wherein, The distance of the second abutment body extending outward along the support body is greater than the distance of the first abutment body extending outward along the support body.

8. The valve support of claim 1 or 2, wherein, The vertical projection of the plurality of first support bodies is on the same radius circle.

9. The valve support of claim 8, wherein, The valve stent comprises a plurality of second support bodies connecting the two first support bodies in the same support unit respectively, and a space between the two first support bodies in the same support unit and the second support body is covered by a sealable layer; The second support body is located in the upstream direction of the first support body; The two first support bodies in the same support unit extend in the downstream direction from both ends of the second support body respectively, and the two first support bodies are connected at the convergence.

10. The valve support of claim 9, wherein, The second support body comprises two transition connecting sections and an anchoring section, two ends of the anchoring section are connected with one end of the two transition connecting sections respectively, the other end of the transition connecting section is connected with the first support body, and the transition connecting section is arranged at an angle with the anchoring section. The anchoring section comprises a protruding section protruding outward along the radial direction of the support main body and used for connecting with a delivery device.

11. A valve stent, characterized by, The support main body and a plurality of abutting support body groups connected with the support main body are used to connect artificial valve leaflets, the abutting support body group comprises a first abutting support body and a second abutting support body used to abut the same native valve leaflet, a containing space is formed between the plurality of abutting support body groups, the support main body is located in the containing space, and the first abutting support body has a deformation space in the radial direction; The first abutting support body is used to abut the inner side of the native valve leaflet, and the second abutting support body is used to abut the outer side of the native valve leaflet; The support main body comprises a plurality of support units, and the plurality of support units surround a channel for blood flow; Each of the support units comprises two first support bodies used to connect different artificial valve leaflets respectively, One end of the two first support bodies in the same support unit is connected with one end of the two adjacent second abutting support bodies through a first connecting piece; One end of the two adjacent first abutting support bodies is connected through the first connecting piece.

12. The valve support of claim 11, wherein, The abutting support body group extends radially outward towards the support main body, and the support main body is in contact with the heart tissue through the abutting support body group.

13. A valve prosthesis, characterized in that, The valve stent comprises the valve stent according to any one of claims 1 to 12; An artificial valve leaflet connected with the first support body; A sealing layer connected with the two first support bodies and the second support body in the same support unit.

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