Anterior-posterior segment synchronous imaging SS-OCT system integrated with optometry function

Abstract

The invention discloses an anterior-posterior segment synchronous imaging SS-OCT system integrated with an optometry function, which comprises an OCT module, an optical coherence tomography module and an optical coherence tomography module, an OCT scanning light beam with the central wavelength of 1060 nanometers is spatially divided into an anterior segment imaging light path for imaging cornea and a whole crystalline lens and a posterior segment imaging light path for imaging retina through a 45-degree light splitting reflecting mirror, and full-eye synchronous imaging of the anterior segment and the posterior segment is achieved at the same time in a scanning period. The optometry module comprises a collimation light source, an annular diaphragm, a semi-reflecting and semi-transmitting mirror, a focusing lens group arranged on one side of a reflecting surface of the semi-reflecting and semi-transmitting mirror, a second dichroscope and a CCD (Charge Coupled Device) arranged behind the focusing lens group which are sequentially arranged along a light path, and is used for dynamically measuring the refraction state of human eyes and feeding back diopter in real time by adopting an optometry method based on a collimation aperture; and the automatic alignment module is used for automatically adjusting the positions of the OCT module and the optometry module according to a positioning result by using a triangulation positioning camera technology so as to ensure that the to-be-detected human eyes are always in the optimal imaging position.

Description

Technical Field

[0001] The present invention relates to the technical field of optical imaging, and in particular to, but not limited to, an SS-OCT system for synchronous imaging of the anterior and posterior ocular segments with integrated optometry function. Background Art

[0002] Eyes are important visual organs of the human body. With the widespread use of electronic devices such as mobile phones and tablets, more and more children, adolescents and the elderly are facing the trouble of eye diseases, which has led to an increasing demand for eye examinations. Eye examinations are usually divided into vision examinations and eye disease screening. Among them, vision examinations mainly measure the refractive power of the eyes, which is often completed with the help of an ophthalmometer; while eye disease screening focuses on the health of the anterior and posterior segments of the eyes. Refractive power measurement is used to evaluate vision problems such as myopia, hyperopia and astigmatism, and its accuracy is directly related to the reasonable configuration of corrective lenses. Eye disease screening includes screening and monitoring of anterior segment diseases such as glaucoma and conjunctivitis, as well as posterior segment diseases such as macular degeneration and diabetic retinopathy. In clinical practice, optical coherence tomography (OCT) has become an important tool for eye disease screening. Due to its advantages of high resolution, fast imaging speed, non-contact and non-destructive, it is widely used for structural examination of the anterior and posterior segments of the eyes. Among them, the swept-source optical coherence tomography (SweptSource OCT, SS-OCT) system uses a swept-source light source to output narrow-linewidth lasers in time sequence, and reconstructs image depth information by Fourier transforming the spectral signal. Compared with time domain and spectral domain systems, it is more suitable for high-scattering samples, has higher sensitivity, imaging speed and signal-to-noise ratio, and has a simple system structure. It is widely used in the measurement of the eye axis and anterior segment.

[0003] Usually, optometry is required before fundus OCT examination. Optometry is to check the focusing of light in the eyeball. Taking the emmetropia as the standard, objects at infinity are imaged on the retina after passing through the corrective lens in front of the eye. The traditional computer ophthalmometer is an objective optometry device. Its principle is to use infrared light beams to pass through the cornea, lens and other eye structures, project them to the retina and return to the instrument. Finally, the CCD receives the light signal and converts it into an electrical signal. Then the effective signal is calculated through the integral formula to obtain the data of sphere, cylinder, axis position, etc., so as to determine the refractive power and provide accurate correction degree for the refractive error of the eye. However, traditional optometry instruments only have the function of refractive power detection and are not combined with OCT structural imaging. Therefore, when conducting an ophthalmic examination, it is often necessary to first undergo optometry and then perform OCT imaging, and the operation process is relatively complicated. At present, there is no integrated device that can perform both optometry and OCT imaging.

[0004] Existing OCT systems are mostly used for imaging the anterior or posterior segment of the eye separately. To achieve whole-eye imaging, it is usually necessary to switch the main scanning optical path of the OCT, or use a dual optical path and dual focus system to image the anterior and posterior segments of the eye respectively, or add a lens in front of the OCT probe to achieve imaging switching. However, these methods are complicated to operate and require adjustment of the reflector position of the reference arm, making it difficult to achieve synchronous imaging. Switching the main scanning optical path by moving the optical elements in the optical path will cause disturbances to the system. Therefore, how to achieve synchronous imaging of the anterior and posterior segments of the eye with minor modifications based on the existing OCT system is an urgent problem to be solved.

[0005] Currently, there are some ophthalmometers and ophthalmic OCT imaging devices, but their multifunctional integration and automation are limited. The devices usually lack precise automatic positioning functions and require operators to manually adjust the position multiple times to align the eye to be tested. This is inefficient and has poor repeatability, and relies on the operator's experience and proficiency. Summary of the invention

[0006] In view of this, an embodiment of the present invention provides an SS-OCT system for synchronous imaging of the anterior and posterior segments of the eye with integrated optometry function, aiming to solve the problems of separation of optometry and OCT imaging, low imaging efficiency, complicated operation process, and lack of precise automatic positioning function.

[0007] The technical solution of the embodiment of the present invention is achieved as follows:

[0008] In a first aspect, an embodiment of the present invention provides an SS-OCT system for synchronous imaging of the anterior and posterior ocular segments with integrated optometry function, comprising:

[0009] The OCT module uses a swept-frequency SS-OCT system, which uses a 45° beam splitter to split the OCT scanning beam with a central wavelength of 1060 nanometers into an anterior segment imaging optical path for imaging the cornea and the entire lens and a posterior segment imaging optical path for imaging the retina, thereby achieving synchronous imaging of the anterior and posterior segments of the entire eye in one scanning cycle;

[0010] The optometry module comprises a collimated light source, an annular aperture arranged in sequence along the optical path, a half-reflecting half-mirror and a focusing lens group arranged on one side of its reflecting surface, a second dichroic mirror and a CCD arranged behind the focusing lens group, and is used to dynamically measure the refractive state of the human eye by using an optometry method based on the collimated aperture and to provide real-time feedback of the refractive power;

[0011] The automatic alignment module includes an oblique-axis camera, a coaxial camera, a first dichroic mirror, and an eye-receiving objective lens, and is used to use a triangulated positioning camera technology to automatically adjust the positions of the OCT module and the optometry module according to the positioning results, so as to ensure that the human eye to be tested is always in the best imaging position.

[0012] In some embodiments, the OCT module includes: a swept frequency light source, a 90:10 fiber coupler, a first circulator, a reference arm module, a sample arm polarization controller, a reference arm polarization controller, a 50:50 fiber coupler, a balanced detector, an image signal acquisition card, a signal generator, a graphics workstation, a display, a second circulator, a sample arm module, and a human eye to be tested;

[0013] The sample arm module comprises a sample arm Y galvanometer, a sample arm X galvanometer, a sample arm optical fiber collimator, a first 45° beam splitter reflector, a second 45° beam splitter reflector, a posterior segment imaging flexion lens, a one-dimensional electric linear displacement platform, an eye-mounted objective lens, a posterior segment imaging optical path reflector group, and an anterior segment imaging optical path reflector group;

[0014] The reference arm module includes a third 45° beam splitting reflector, a first reference arm corresponding to the anterior segment imaging optical path, a reference arm fiber optic collimator, a reference arm Y galvanometer, a reference arm X galvanometer, and a second reference arm corresponding to the posterior segment imaging optical path.

[0015] In some embodiments, in the OCT module, a swept frequency light source is input into the sample arm optical path and the reference arm optical path respectively through a 90:10 optical fiber coupler; the light beam in the sample arm optical path is scanned by the sample arm optical fiber collimator, the sample arm X galvanometer, and the sample arm Y galvanometer in sequence, and then split by a first 45° beam splitter reflector, wherein the light beam irradiated to the upper reflection surface of the first 45° beam splitter reflector is focused to the retina through the posterior segment imaging optical path, and the light beam irradiated to the lower reflection surface of the first 45° beam splitter reflector is focused to the cornea through the anterior segment imaging optical path;

[0016] The posterior segment imaging optical path includes a posterior segment imaging optical path reflector group, a posterior segment imaging refractive lens, an upper reflective surface of a second 45° beam splitting reflector, and an eye-mounted objective lens; wherein the posterior segment imaging refractive lens is mounted on a one-dimensional electric linear displacement platform for horizontal position movement to achieve diopter adjustment; the anterior segment imaging optical path includes an anterior segment imaging optical path reflector group, a lower reflective surface of a second 45° beam splitting reflector 23, and an eye-mounted objective lens.

[0017] In some embodiments, the first reference arm includes a first beam returner and a first voice coil motor; the second reference arm includes a folding light path reflector, a second beam returner, and a second voice coil motor; the folding light path reflector is used to fold the light emitted from the reference arm collimator into the second beam returner; the first voice coil motor and the second voice coil motor are used to adjust the positions of the first beam returner and the second beam returner, respectively, so as to adjust the optical path difference between the reference arm module and the sample arm module, and perform axial motion compensation for the physiological movement of the eye.

[0018] In some embodiments, the reference arm Y galvanometer and the reference arm X galvanometer of the reference arm module, and the sample arm Y galvanometer and the sample arm X galvanometer of the sample arm module are controlled by a synchronization control signal to perform synchronous scanning with consistent scanning angles.

[0019] In some embodiments, in the optometry module, the collimated light source passes through the annular aperture to form a collimated aperture, which passes through the semi-transparent and semi-reflective mirror group in turn. 、 The second dichroic mirror is guided into the pupil of the human eye to be tested, and the human eye causes the collimated aperture to form a diffusion ring on the retina, and the diffusion ring is reflected back to the optometry module through the human eye, and is reflected again to the focusing lens group through the semi-transparent and semi-reflective mirror group; the focusing lens group is responsible for dynamically adjusting the focal length to collect the reflection ring image reflected back by the eye through the CCD; the reflection image distance is determined according to the change of the ring thickness of the reflection ring at different distances, and then the refractive power parameter of the human eye is solved by the calculation formula.

[0020] In some embodiments, the oblique-axis camera in the automatic alignment module is arranged below the eye-mounted objective lens, and its optical axis is at a preset angle to the optical axis of the eye-mounted objective lens, so as to capture oblique-angle images of the eye within a larger field of view and provide rough positioning information; the coaxial camera in the automatic alignment module is located behind the eye-mounted objective lens, and captures a forward coaxial image of the eye in a small field of view through the first dichroic mirror. After the optical axis is refracted by the first dichroic mirror, it becomes coaxial with the optical axis of the eye-mounted objective lens, so as to refine the positioning result and provide higher-precision eye alignment data; wherein, the first dichroic mirror is designed as a spectrometer that transmits 1060nm infrared light and reflects visible light, so as to guide the eye image to the coaxial camera, while ensuring that there is no interference in the optical path to achieve precise imaging.

[0021] In some embodiments, all components of the sample arm in the OCT module, all components of the optometry module, and all components of the automatic alignment module are encapsulated and fixed in an imaging probe, and the imaging probe is mounted on a three-dimensional electric displacement platform; when the system is in use, the position of the imaging probe is adjusted by moving the three-dimensional electric displacement platform to obtain the best imaging effect.

[0022] The beneficial effects brought about by the technical solution provided by the embodiment of the present invention include at least:

[0023] The SS-OCT system for synchronous imaging of the anterior and posterior segments of the eye with integrated optometry function provided by the present invention can simultaneously complete the eye refractive power measurement and high-resolution imaging of the anterior and posterior segments of the eye in one examination on the same instrument by integrating automatic optometry and OCT imaging functions, thereby significantly improving the convenience and efficiency of the examination. At the same time, by introducing a fully automatic alignment module, high-precision eye positioning and alignment are achieved, reducing the dependence of operators and manual operation steps, thereby improving the automation level of the system and the consistency of detection. The alignment module adopts triangulation camera technology, which can quickly and accurately capture the eye position and automatically adjust the position of the device to ensure the accuracy of the optometry and OCT imaging process. In addition, by using the voice coil motor in the reference arm, dynamic adjustment of the optical path difference is achieved to adapt to the axial movement of the eyeball, thereby improving the imaging quality and reliability. By performing OCT scanning at a wavelength of 1060nm, the present invention can simultaneously obtain the structural information of the anterior and posterior segments of the eye, realize the real synchronous imaging of the whole eye, and avoid the complexity of optical path switching or dual optical path system in traditional OCT systems. The present invention realizes an integrated, fully automatic, high-precision ophthalmic examination system by integrating innovative means such as optometry function, automatic alignment, and dynamic optical path difference compensation. The system is suitable for clinical diagnosis and portable application scenarios, and can significantly improve the efficiency and accuracy of ophthalmic examinations. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the following briefly introduces the drawings required for describing the embodiments. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative work, among which:

[0025] Figure 1 A schematic diagram of the system architecture of an SS-OCT system for synchronous imaging of the anterior and posterior ocular segments with integrated optometry function provided in an embodiment of the present invention;

[0026] Figure 2 A schematic diagram of the structure of an OCT module in the SS-OCT system for synchronous imaging of the anterior and posterior segments of the eye with integrated optometry function provided in an embodiment of the present invention;

[0027] Figure 3 A schematic diagram of the structure of an optical path for anterior segment imaging by an OCT module in an SS-OCT system for synchronous imaging of the anterior and posterior segments of the eye with an integrated optometry function provided in an embodiment of the present invention;

[0028] Figure 4 A schematic diagram of the structure of the optical path for realizing posterior segment imaging by an OCT module in the SS-OCT system for synchronous imaging of the anterior and posterior segments of the eye with an integrated optometry function provided in an embodiment of the present invention;

[0029] Figure 5A schematic diagram of the structure of an optometry module in an SS-OCT system for synchronous imaging of the anterior and posterior segments of the eye with an integrated optometry function provided in an embodiment of the present invention;

[0030] Figure 6 A schematic diagram of the structure of an automatic alignment module in an SS-OCT system for synchronous imaging of the anterior and posterior segments of the eye with an integrated optometry function provided in an embodiment of the present invention;

[0031] Figure 7 A schematic diagram of the overall structure of an SS-OCT system for synchronous imaging of the anterior and posterior ocular segments with integrated optometry function provided in an embodiment of the present invention;

[0032] Markings in the figure: 1-sweep frequency light source; 2-90:10 fiber coupler; 3-first circulator; 4-third 45° splitter reflector; 5-first reference arm, 51-first reflector, 52-first beam returner, 53-first voice coil motor; 6-reference arm fiber collimator; 7-reference arm Y galvanometer; 8-reference arm X galvanometer; 9-second reference arm, 91-second reflector, 92-second beam returner, 93-second voice coil motor; 10-sample arm polarization controller; 11-reference arm polarization controller; 12-50:50 fiber coupler; 13-balanced detector; 14-image signal acquisition card; 15-signal generator; 16-graphic workstation; 17-display; 18-second Circulator; 19-sample arm Y galvanometer; 20-sample arm X galvanometer; 21-sample arm fiber collimator; 22-first 45° beam splitter reflector; 23-second 45° beam splitter reflector; 24-posterior segment imaging flexure lens; 25-first dichroic mirror; 26-coaxial camera; 27-eye-mounting objective lens; 28-posterior segment imaging light path reflector group; 29-anterior segment imaging light path reflector group; 30-CCD; 31-focusing lens group; 32-half-reflecting half-mirror group; 33-annular aperture; 34-collimated light source; 35-second dichroic mirror; 36-sample arm module; 37-oblique axis camera; 38-human eye to be tested; 39 oblique axis camera focusing lens; 40-one-dimensional electric linear displacement platform. DETAILED DESCRIPTION

[0033] In order to make the purpose, technical scheme and advantages of the embodiments of the present invention clearer, the technical scheme in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are part of the embodiments of the present invention, rather than all the embodiments. The following embodiments are used to illustrate the present invention, but are not used to limit the scope of the present invention. Based on the embodiments in the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention.

[0034] In the following description, reference is made to “some embodiments”, which describe a subset of all possible embodiments, but it will be understood that “some embodiments” may be the same subset or different subsets of all possible embodiments and may be combined with each other without conflict.

[0035] It should be pointed out that the terms "first\second\third" involved in the embodiments of the present invention are only used to distinguish similar objects and do not represent a specific ordering of the objects. It can be understood that "first\second\third" can be interchanged in a specific order or sequence where permitted, so that the embodiments of the present invention described here can be implemented in an order other than that illustrated or described here.

[0036] It will be understood by those skilled in the art that, unless otherwise defined, all terms (including technical and scientific terms) used herein have the same meaning as those generally understood by those skilled in the art in the field to which the embodiments of the present invention belong. It should also be understood that terms such as those defined in general dictionaries should be understood to have meanings consistent with those in the context of the prior art, and will not be interpreted with idealized or overly formal meanings unless specifically defined as here.

[0037] Optical coherence tomography (OCT) is a non-invasive, high-resolution imaging technology that is superior to traditional imaging methods such as CT, MRI, and ultrasound. It is widely used to measure ophthalmic biological parameters such as corneal morphology, corneal thickness, anterior chamber angle, lens thickness, axial length, retinal three-dimensional structure, and retinal vascular distribution. Due to the limited coherence length of the light source in the OCT system and the inherent limitation of the imaging depth due to light attenuation caused by absorption and scattering inside non-transparent tissues, the imaging depth of the OCT system is usually less than 4mm, while the standard length of the human eye is 28-35mm. Therefore, imaging of the anterior segment (such as cornea, lens) and the posterior segment (retina) of the eye needs to be performed twice. Usually, imaging of the anterior segment requires focusing the OCT beam onto the corneal surface through a focusing lens, while imaging of the posterior segment requires parallelizing the beam and focusing it onto the retina through the human lens.

[0038] The embodiment of the present invention provides an SS-OCT system for synchronous imaging of the anterior and posterior ocular segments with integrated optometry function, and the system architecture diagram is shown in FIG. Figure 1 As shown, including:

[0039] The OCT module 101 adopts a swept frequency SS-OCT system, which divides the OCT scanning beam with a central wavelength of 1060 nanometers into an anterior segment imaging optical path for imaging the cornea and the entire lens and a posterior segment imaging optical path for imaging the retina through a 45° beam splitting reflector, thereby achieving synchronous imaging of the anterior segment and the posterior segment of the whole eye in one scanning cycle;

[0040] The optometry module 102 includes a collimated light source, an annular aperture arranged in sequence along the optical path, a half-reflecting half-mirror and a focusing lens group arranged on one side of its reflecting surface, a second dichroic mirror, and a CCD arranged behind the focusing lens group, and is used to dynamically measure the refractive state of the human eye using an optometry method based on the collimated aperture and provide real-time feedback of the refractive power;

[0041] The automatic alignment module 103 includes an oblique axis camera, a coaxial camera, a first dichroic mirror, and an eye-mounting objective lens, and is used to use triangulated positioning camera technology to automatically adjust the positions of the OCT module and the optometry module according to the positioning results to ensure that the human eye to be tested is always in the best imaging position.

[0042] Here, the present invention adopts a swept frequency OCT (SS-OCT) system, and through scanning spectrophotometry, image acquisition and image integration technology, the whole eye OCT B-scan image can be obtained simultaneously in one scanning cycle, and the whole eye synchronous imaging of the anterior segment and the posterior segment of the eye can be realized. The OCT module 101 uses a central wavelength 1060nm infrared swept frequency light source with a small scattering coefficient and a large penetration depth in the intraocular tissue, a sweep frequency speed of 200Kz, a tuning range greater than 105nm, a coherence length greater than 10mm, and a scanning depth of 3.7mm in the air. The wavelength of 1060nm can penetrate the eye tissue more deeply to obtain biological parameters such as corneal morphology, corneal thickness, anterior chamber angle, lens thickness, and retinal structure.

[0043] The optometry module 102 is integrated in the SS-OCT system, and determines the degree of vision problems (such as myopia, hyperopia, and astigmatism) by measuring the refractive power of the human eye. The optometry module adopts an optometry method based on a collimated aperture, using an infrared collimated light source, combined with an annular aperture and a focusing lens group, to dynamically measure the refractive state of the human eye and provide real-time feedback on the refractive power. In implementation, an infrared light beam is used to illuminate the eyeball, and the infrared light passes through the cornea and lens and then irradiates the retina, and then returns to the optical system, receives the signal through the CCD, and uses a calculation formula to solve the eye's refractive power parameters. The obtained refractive power information can be used to determine the refractive error, thereby providing support for the refractive correction of the eye. The optometry module 102 is integrated with the OCT module 101, and optometry and imaging can be performed simultaneously in the same system.

[0044] The automatic alignment module 103 adopts triangulated positioning camera technology, and realizes real-time monitoring and precise alignment of the human eye to be tested by configuring multiple high-precision cameras and intelligent positioning algorithms. The system automatically adjusts the position of the OCT module and the optometry module according to the positioning results to ensure that the human eye to be tested is always in the optimal imaging position. This module not only avoids the errors and inefficiencies of manual alignment, but also significantly improves the convenience of operation and the consistency of imaging. It includes the following key components: an oblique-axis camera, which is used to capture oblique-angle images of the eye within a larger field of view, provide rough positioning information, and lay the foundation for the system to quickly capture the eye position; a coaxial camera, which is used to refine the positioning results and provide higher-precision eye alignment data; a first dichroic mirror, which is used to guide the eye image to the coaxial camera, while ensuring that the optical path is free of interference to achieve precise imaging. The workflow is as follows:

[0045] Large field of view coarse positioning: The oblique axis camera captures the oblique angle image of the human eye to be tested within a large field of view, and preliminarily determines the position and direction of the eye by calculating the X-axis and Y-axis offsets between the center of the pupil of the human eye to be tested and the center of the eye-receiving objective lens. According to the X-axis and Y-axis offsets, the control device controls the three-dimensional electric displacement platform to move the imaging probe in the X-axis and Y-axis directions;

[0046] Fine positioning in a small field of view: The coaxial camera collects the positive coaxial image through the first dichroic mirror to further refine the position parameters of the eye and provide precise alignment information.

[0047] Automatically adjust the distance between the imaging probe and the eye to be tested (Z-axis adjustment): The system combines the data collected by the oblique camera and the coaxial camera, and calculates the optimal imaging distance between the imaging probe and the eye to be tested through the principle of triangulation. And automatically adjust the position of the OCT module and the optometry module.

[0048] In some embodiments, the OCT module includes: a swept light source, a 90:10 fiber coupler, a first circulator, a reference arm module, a sample arm polarization controller, a reference arm polarization controller, a 50:50 fiber coupler, a balanced detector, an image signal acquisition card, a signal generator, a graphics workstation, a display, a second circulator, a sample arm module and a human eye to be tested; the sample arm module includes a sample arm Y galvanometer, a sample arm X galvanometer, a sample arm fiber collimator, a first 45° beam splitter reflector, a second 45° beam splitter reflector, a posterior segment imaging flexure lens, a one-dimensional electric linear displacement platform, an eye-mounted objective lens, a posterior segment imaging light path reflector group, and anterior segment imaging light path reflector group; the reference arm module includes a third 45° beam splitter reflector, a first reference arm corresponding to the anterior segment imaging light path, a reference arm fiber collimator, a reference arm Y galvanometer, a reference arm X galvanometer, and a second reference arm corresponding to the posterior segment imaging light path.

[0049] like Figure 2The figure shows a schematic diagram of the structure of an OCT module in an SS-OCT system for synchronous imaging of the anterior and posterior segments of the eye with an integrated optometry function provided by an embodiment of the present invention. The OCT module is designed based on the swept-source light source (SS-OCT) technology and covers the imaging requirements of the anterior and posterior segments of the eye. Main components: 200kHz swept frequency light source 1, 90:10 fiber coupler 2, first circulator 3, reference arm module (including reference arm collimator 6, reference arm Y galvanometer 7, reference arm X galvanometer 8, third 45° beam splitter reflector 4, first reference arm 5, second reference arm 9), sample arm polarization controller 10, reference arm polarization controller 11, 50:50 fiber coupler 12, balanced detector 13, image signal acquisition card 14, signal generator 15, graphic workstation 16, display 17, second circulator 18, sample arm module 36 (including sample arm Y galvanometer 19, sample arm X galvanometer 20, sample arm fiber collimator 21, first 45° beam splitter reflector 22, second 45° beam splitter reflector 23, posterior segment imaging flexure lens 24, one-dimensional electric linear displacement platform 40, eye-mounted objective lens 27, posterior segment imaging light path reflector group 28, anterior segment imaging light path reflector group 29) and human eye to be tested 38.

[0050] Among them, the 90:10 fiber coupler 2 is used to divide the light beam of the swept frequency light source into two parts, which enter the reference arm light path and the sample arm light path respectively and receive the light beams returned by the reference arm light path and the sample arm light path; the light entering the sample arm light path is 90% of the light power of the light source, and the light entering the reference arm light path is 10% of the light power of the light source.

[0051] The circulator 3 spatially separates the incident light from the reflected light path. The light from the swept frequency light source 1 is split by the 90:10 fiber coupler 2, and is transmitted from port 1 to port 2 of the two circulators (the first circulator 3 and the second circulator 18), and then enters the sample arm module and the reference arm module respectively. The light reflected from the sample arm module and the light reflected from the reference arm module are respectively transmitted from port 2 to port 3 of the two circulators, and then meet at the 50:50 fiber coupler 12 to interfere.

[0052] The sample arm polarization controller 10 and the reference arm polarization controller 11 adjust the polarization states of the light beams of the sample arm module and the reference arm module by twisting the optical fiber.

[0053] The backscattered light of the sample arm module returns along the original path, interferes with the reflected light of the reference arm module, and is converted into an electrical signal by the balanced detector 13 and enters the image signal acquisition card 14. The A-trigger signal is a TTL signal emitted by the swept frequency light source 1 with the same sweep frequency cycle as the light source. The rising edge triggers the image signal acquisition card 14 to collect the OCT signal. After the acquisition is completed, it is uploaded to the graphic workstation 16 by the PCIe bus, and the OCT signal is resampled and Fourier transformed, and finally the OCT image is displayed in real time on the display 17.

[0054] The balanced detector 13 is used to receive the interference signal formed by the interference of the light beams returned by the reference arm module and the sample arm module, and convert it into an electrical signal;

[0055] The image signal acquisition card 14 is used to receive the electrical signal and process it.

[0056] The graphic workstation 16 is used to process the spectral signal through a series of signal processing such as Fourier transform and grayscale mapping, and display the OCT image on the display 17 in real time.

[0057] In some embodiments, in the OCT module, a swept frequency light source is input into the sample arm optical path and the reference arm optical path respectively through a 90:10 fiber coupler; the light beam in the sample arm optical path is scanned by the sample arm fiber collimator, the sample arm X galvanometer, and the sample arm Y galvanometer in sequence, and then split by the first 45° beam splitter reflector, wherein the light beam irradiated to the upper reflection surface of the first 45° beam splitter reflector is focused to the retina through the posterior segment imaging optical path, and the light beam irradiated to the lower reflection surface of the first 45° beam splitter reflector is focused to the cornea through the anterior segment imaging optical path; the posterior segment imaging optical path includes a posterior segment imaging optical path reflector group, a posterior segment imaging refractive lens, an upper reflection surface of a second 45° beam splitter reflector, and an eye-mounted objective lens; wherein the posterior segment imaging refractive lens is mounted on a one-dimensional electric linear displacement platform for horizontal position movement to achieve diopter adjustment; the anterior segment imaging optical path includes an anterior segment imaging optical path reflector group, a lower reflection surface of the second 45° beam splitter reflector 23, and an eye-mounted objective lens.

[0058] Here, if Figure 2As shown, the working principle of the OCT imaging module is as follows: the light output by the OCT frequency sweeping light source 1 is divided into two beams through the 90:10 fiber coupler 2 to provide light to the sample arm module 36 and the reference arm module; 90% of the light enters the sample arm module 36 through the first circulator 18, and 10% of the light enters the reference arm module through the second circulator 3. The reference arm module is a first reference arm 5 and a second reference arm 9 with two different optical path lengths, which correspond to the anterior segment imaging optical path and the posterior segment imaging optical path respectively. When the galvanometer scans the light beam to the lower reflection surface of the third 45° beam splitter reflector 4, the light beam is incident on the first reference arm 5, and when the galvanometer scans the light beam to the upper reflection surface of the third 45° beam splitter reflector 4, the light beam is incident on the second reference arm 9. Among them, the beam returner of the reference arm module reflects the light back along the original path, passes through the second circulator 3, and is incident on the 50:50 fiber coupler; the light beam incident on the sample arm module 36 passes through the first circulator 18, the sample arm collimator 21, the sample arm Y galvanometer 19, and the sample arm X galvanometer 20. When the two galvanometers scan the light beam to the lower reflection surface of the first beam splitting reflector 22, the light beam sequentially passes through the anterior segment reflector group 29, the lower reflection surface of the second beam splitting reflector 23, and the eye-connecting objective lens 27, and then is focused on the corneal surface of the eye. When the two galvanometers scan the light beam to the upper reflection surface of the first 45° beam splitting reflector 22, the light beam sequentially passes through the posterior segment reflector group 28, the posterior segment adjustment lens group 24, the upper reflection surface of the second 45° beam splitting reflector 23, and the eye-connecting objective lens 27, and then is incident on the eye, passes through the pupil, and is focused on the retina through the lens.

[0059] The light reflected by the eye returns along the original path and interferes with the light reflected by the reference arm module in the 50:50 fiber coupler 12. The interference light is transmitted to the balanced detector 13, and then the spectrum is collected by the image acquisition card 14. The spectrum signal is transmitted to the graphics workstation 16 for Fourier transform and other signal processing. Finally, the display 17 displays the OCT image of the sample under test.

[0060] like Figure 3 The structural diagram of the anterior segment imaging optical path shown in the figure shows that the light transmitted to the reference arm module enters the first reference arm. The light transmitted to the sample arm module passes through the sample arm fiber collimator 21 and is incident on the sample arm Y galvanometer 19 and the sample arm X galvanometer 20. Then, after being deflected by the galvanometer, the light beam is irradiated to the lower reflection surface of the first 45° beam splitter 22 and the lower reflection surface of the second 45° beam splitter 23, and is reflected by the anterior segment reflector group 29 and focused on the corneal surface of the eye after being connected to the eye objective lens 27.

[0061] like Figure 4The schematic diagram of the structure of the imaging optical path of the posterior segment of the eye is shown. The light transmitted to the reference arm module enters the second reference arm. The light transmitted to the sample arm module passes through the sample arm fiber collimator 21, and then is incident on the sample arm Y galvanometer 19 and the sample arm X galvanometer 20. Then, after being deflected by the galvanometer, the light beam is irradiated to the reflection surface on the first 45° beam splitting reflector 22 and the reflection surface on the second 45° beam splitting reflector 23, and passes through the posterior segment adjustment lens group 24, is reflected by the posterior segment reflector group 28, and enters from the pupil of the human eye after passing through the eye-mounted objective lens 27, and is focused on the retinal surface. The adjustment lens 24 is used to adjust the parallelism of the OCT measurement beam according to the different diopters of the human eye to be tested so that it is just focused on the retina of the human eye to be tested. Specifically, the adjustment lens is fixed on the one-dimensional electric linear displacement platform 40, and the parallelism of the beam is changed by moving the lens position back and forth to adapt to different diopters, so as to correct the patient's refractive error between ±12.6 and +9.9d.

[0062] In some embodiments, the first reference arm includes a first beam returner and a first voice coil motor; the second reference arm includes a folding light path reflector, a second beam returner, and a second voice coil motor; the folding light path reflector is used to fold the light emitted from the reference arm collimator into the second beam returner; the first voice coil motor and the second voice coil motor are used to adjust the positions of the first beam returner and the second beam returner, respectively, so as to adjust the optical path difference between the reference arm module and the sample arm module, and perform axial motion compensation for the physiological movement of the eye.

[0063] Here, if Figure 2 As shown, the first reference arm 5 includes a first reflector 51, a first beam returner 52, and a first voice coil motor 53. The second reference arm 9 includes devices of the same type as those used by the first reference arm (including a second reflector 91, a second beam returner 92, and a second voice coil motor 93), and the optical path is longer than that of the first reference arm 5. Through the application of the voice coil motor, dynamic adjustment of the optical path difference is achieved to adapt to the axial movement of the eyeball, thereby improving the imaging quality and reliability. By performing OCT scanning at a wavelength of 1060nm, the present invention can simultaneously obtain structural information of the anterior and posterior segments of the eye, realize true whole-eye synchronous imaging, and avoid the complexity of optical path switching or dual optical path systems in traditional OCT systems.

[0064] In the embodiment of the present invention, voice coil motors are added to the first reference arm and the second reference arm to quickly adjust the position of the corresponding beam returner and adjust the optical path difference to compensate for the axial movement of the eye. This innovative design effectively simplifies the operation process, improves imaging accuracy and efficiency, and is suitable for application in medical institutions and portable devices.

[0065] In some embodiments, the reference arm Y galvanometer and the reference arm X galvanometer of the reference arm module, and the sample arm Y galvanometer and the sample arm X galvanometer of the sample arm module are controlled by a synchronization control signal to perform synchronous scanning with consistent scanning angles.

[0066] Here, the reference arm Y galvanometer, the reference arm X galvanometer, the sample arm Y galvanometer, and the sample arm X galvanometer have the same structure, and are all composed of a reflector, a rotating shaft, and a galvanometer motor, wherein the galvanometer motor is connected to the rotating shaft, and the rotating shaft is connected to the reflector. By controlling the XY scanning galvanometer of the reference arm module and the XY scanning galvanometer of the sample arm module to scan synchronously, the scanning angles are consistent, so that when the light beam in the sample arm module passes through the posterior segment imaging optical path, the light beam in the reference arm module passes through the second reference arm, corresponding to a long optical path; when the light beam in the sample arm module passes through the anterior segment imaging optical path, the light beam in the reference arm module passes through the first reference arm, corresponding to a short optical path.

[0067] In practice, the scanning galvanometer (sample arm X galvanometer, sample arm Y galvanometer) is driven by a galvanometer driver, the galvanometer driver is connected to a galvanometer power supply, the galvanometer driver is connected to a signal generator, and the signal generator sends a scanning voltage signal to the galvanometer driver. By deflecting the scanning galvanometer at high speed, the spot of the OCT beam is scanned and moved.

[0068] In some embodiments, in the optometry module, the collimated light source passes through the annular aperture to form a collimated aperture, which passes through the semi-transparent and semi-reflective mirror group in turn. 、 The second dichroic mirror is guided into the pupil of the human eye to be tested, and the human eye causes the collimated aperture to form a diffusion ring on the retina, and the diffusion ring is reflected back to the optometry module through the human eye, and is reflected again to the focusing lens group through the semi-transparent and semi-reflective mirror group; the focusing lens group is responsible for dynamically adjusting the focal length to collect the reflection ring image reflected back by the eye through the CCD; the reflection image distance is determined according to the change of the ring thickness of the reflection ring at different distances, and then the refractive power parameter of the human eye is solved by the calculation formula.

[0069] like Figure 5 The figure shows a schematic diagram of the structure of an optometry module in an SS-OCT system for synchronous imaging of the anterior and posterior ocular segments with integrated optometry function provided by an embodiment of the present invention. The optometry module mainly comprises: a collimated light source 34, an annular aperture 33, a semi-reflective semi-mirror 32, a focusing lens group 31, a CCD 30, a second dichroic mirror 35 and a human eye to be tested 38.

[0070] The collimated light source 34 uses a collimated laser light source with a wavelength of 900-980nm, emitting circular collimated infrared light. The human eye is not sensitive to light within this infrared light wavelength range, which can effectively relax the ciliary muscle, making the test closer to the natural state. The selection of the annular aperture parameters takes into account the aperture's transmittance and measurement accuracy, ensuring that the system can accurately detect.

[0071] An annular aperture 33 is provided on the optical path in front of the collimated light source 34. The annular aperture 33 is a coated glass that allows the collimated aperture with a diameter of 3 mm to pass through. A semi-reflective half-mirror 32 and a second dichroic mirror 35 are provided in front of the annular aperture 33. The second dichroic mirror 35 can reflect 980nm light and transmit 1060nm light, and is used to inject the collimated aperture from the collimated light source 34 into the pupil of the human eye 38 to be tested; the splitting ratio of the semi-reflective half-mirror 32 is 1:1. A focusing lens group 31 is provided on one side of the reflecting surface of the semi-reflective half-mirror 32. The focusing lens group 31 is composed of a series of mutually parallel achromatic lenses, and the focal length of the lens group is changed by adjusting the lens spacing. A CCD 30 is provided behind the focusing lens group 31 to collect the annular collimated aperture image reflected back by the eye.

[0072] The collimated infrared light emitted by the collimated light source 34 passes through the annular aperture 33 to form a collimated aperture with a diameter of 3 mm and a ring thickness of about 0.5 mm; the collimated aperture passes through the half-reflecting half-mirror 32 and is captured by the reflection surface of the second dichroic mirror 35, and is reflected by the second dichroic mirror 35 into the pupil of the human eye to be tested, and is projected onto the retina through the lens. Then, the collimated aperture is reflected from the retina of the human eye to the reflection surface of the second dichroic mirror 35, and then reflected to the reflection surface of the half-reflecting half-mirror 32, and then incident on the focusing lens group 31, which focuses the reflected collimated aperture onto the CCD surface.

[0073] In implementation, the focal length is dynamically adjusted by moving the focusing lens group 31, and the CCD collects a series of collimated apertures, i.e., reflection ring images, at different distances relative to the human eye. The ring thickness of the collimated aperture is analyzed, and according to the change in the ring thickness of the reflection ring at different distances, the distance relative to the human eye at the narrowest point of the ring thickness is determined as the reflection image distance, and the refractive power is calculated by the reflection image distance. The specific calculation formula is S=-1 / d, wherein S is the refractive power and d is the reflection image distance.

[0074] In some embodiments, the oblique-axis camera in the automatic alignment module is arranged below the eye-mounted objective lens, and its optical axis is at a preset angle to the optical axis of the eye-mounted objective lens, so as to capture oblique-angle images of the eye within a larger field of view and provide rough positioning information; the coaxial camera in the automatic alignment module is located behind the eye-mounted objective lens, and captures a forward coaxial image of the eye in a small field of view through the first dichroic mirror. After the optical axis is refracted by the first dichroic mirror, it becomes coaxial with the optical axis of the eye-mounted objective lens, so as to refine the positioning result and provide higher-precision eye alignment data; wherein, the first dichroic mirror is designed as a spectrometer that transmits 1060nm infrared light and reflects visible light, so as to guide the eye image to the coaxial camera, while ensuring that there is no interference in the optical path to achieve precise imaging.

[0075] like Figure 6The figure shows a schematic diagram of the structure of an automatic alignment module in an SS-OCT system for synchronous imaging of the anterior and posterior segments of the eye with integrated optometry function provided by an embodiment of the present invention. The automatic alignment module uses an oblique axis camera and a coaxial camera in combination with a triangulation positioning algorithm to adjust the system optical path position in real time so that the human eye to be tested is in the best position. The main components include an oblique axis camera 37, a focusing lens 39 of the oblique axis camera, a coaxial camera 26, a first dichroic mirror 25, and an eye-receiving objective lens 27.

[0076] Among them, the oblique axis camera 37 is set below the eye-receiving objective lens 27, and forms a preset angle with the optical axis of the eye-receiving objective lens, and is used to capture oblique angle images of the eye within a larger field of view, provide rough positioning information, and lay the foundation for the system to quickly capture the position of the eye. According to the oblique angle eye image captured by the oblique axis camera 37, the pupil is automatically identified, the center coordinates of the pupil of the human eye to be tested are calculated, the position of the human eye 38 to be tested is calculated, and the offset of the X-axis and Y-axis movement of the three-dimensional mobile control unit is calculated according to the real coordinates of the pupil of the human eye 38 to be tested. According to the offset of the movement in the X-axis and Y-axis directions, the position of the mobile probe assembly (including the sample arm assembly, optometry module assembly and automatic alignment module assembly of the OCT module) of the three-dimensional mobile control unit in the X-axis and Y-axis directions is controlled.

[0077] The coaxial camera 26 is located behind the eye-mounted objective lens 27, and captures a coaxial image of the eye in a small field of view through the first dichroic mirror 25. After the optical axis is reflected by the first dichroic mirror 25, it becomes coaxial with the optical axis of the eye-mounted objective lens 27. The coaxial camera 26 is used to refine the positioning result and provide more accurate eye alignment data.

[0078] Among them, the first dichroic mirror 25 is designed as a spectroscope that transmits 1060nm infrared light and reflects visible light, and is used to guide the eye image to the coaxial camera 26 while ensuring that the optical path is free of interference to achieve accurate imaging.

[0079] After monitoring that the human eye 38 to be tested is placed directly in front of the eye-receiving objective lens 27, the coaxial camera 26 captures a small-field pupil image, and calculates the relative position of the human eye 38 to be tested relative to the center of the optical path based on the eye image captured by the coaxial camera 26. The three-dimensional mobile control unit adjusts the probe assembly based on the relative position of the human eye 38 to be tested relative to the center of the optical path to align the optical path with the center of the pupil.

[0080] Then, the image captured by the oblique camera 37 and the image captured by the coaxial camera 26 are combined with the triangulation positioning algorithm, and the three-dimensional mobile control unit is used to automatically adjust the imaging probe in the Z direction, where the Z direction refers to the direction perpendicular to the plane parallel to the eye to be tested 38. The triangulation positioning algorithm means that according to the preset setting, the intersection of the optical path center of the coaxial camera 26 and the optical path center of the oblique camera 37 is located at the center of the pupil, that is, when the center of the coaxial camera and the center of the oblique camera are both aligned with the center of the pupil, the probe is located at the best imaging position.

[0081] In some embodiments, all components of the sample arm in the OCT module, all components of the optometry module, and all components of the automatic alignment module are encapsulated and fixed in an imaging probe, and the imaging probe is mounted on a three-dimensional electric displacement platform; when the system is in use, the position of the imaging probe is adjusted by moving the three-dimensional electric displacement platform to obtain the best imaging effect.

[0082] The present invention proposes an SS-OCT system for synchronous imaging of the anterior / posterior segments with integrated optometry function, such as Figure 7 As shown, the overall structure includes the above-mentioned optometry module, OCT module, and automatic alignment module, which has the following significant beneficial effects:

[0083] 1) Functional integration and simplified operation process: The present invention integrates the optometry function and the OCT imaging function into the same device. Users do not need to frequently switch between different devices, which greatly simplifies the operation process, improves inspection efficiency, and reduces equipment configuration and maintenance costs.

[0084] 2) Synchronous imaging of the anterior and posterior segments, covering all detection needs: This invention adopts a new optical design based on a swept-frequency light source (SS-OCT), which breaks through the depth limitation of traditional OCT imaging and realizes synchronous imaging of the anterior and posterior segments of the eye. This design not only avoids the disturbance caused by optical path switching, but also significantly improves the speed and stability of imaging, meeting the comprehensive detection needs of the entire eye structure.

[0085] 3) Automatic alignment technology improves imaging efficiency and consistency: By configuring oblique axis cameras and coaxial cameras, combined with triangulation positioning algorithms and automatic adjustment mechanisms, rapid positioning and automatic alignment of the human eye to be tested are achieved. This avoids the errors and inefficiencies of traditional manual adjustments, improves the ease of use of the equipment and the consistency of imaging results, and significantly improves the clinical application value.

[0086] 4) Dynamic optical path adjustment to adapt to different axial lengths: The voice coil motor built into the reference arm module can quickly adjust the position of the beam returner and dynamically compensate for the optical path difference caused by the axial movement of the eye, ensuring that the system maintains high-quality imaging during long-term examinations and adapting to the detection needs of patients with different axial lengths.

[0087] 5) Dynamic adjustment of refractive power: When imaging the posterior segment of the eye, the posterior segment imaging refractive power adjustment lens in the optical path is fixed on a one-dimensional electric linear displacement platform. The parallelism of the OCT beam incident on the human eye can be adjusted by adjusting the position of the lens, thereby adapting to the detection of patients with different refractive powers.

[0088] 6) Non-invasive and highly comfortable design: This system uses an infrared light source with a central wavelength of 1060nm, which has good biological tissue penetration ability. At the same time, it avoids the discomfort that visible light stimulation may cause to patients, ensuring that the detection process is safe, comfortable and non-traumatic.

[0089] 7) Portability and wide applicability: The system is compactly designed and suitable for routine diagnostic applications in medical institutions. It also has the potential for portability and can be expanded into community screening or home testing equipment, significantly improving the early detection rate and diagnosis and treatment coverage of ophthalmic diseases.

[0090] It should be understood that "one embodiment" or "an embodiment" mentioned throughout the specification means that specific features, structures or characteristics related to the embodiment are included in at least one embodiment of the present invention. Therefore, "in one embodiment" or "in an embodiment" appearing throughout the specification does not necessarily refer to the same embodiment. In addition, these specific features, structures or characteristics can be combined in one or more embodiments in any suitable manner. It should be understood that in various embodiments of the present invention, the size of the serial number of the above-mentioned processes does not mean the order of execution. The execution order of each process should be determined by its function and internal logic, and should not constitute any limitation on the implementation process of the embodiment of the present invention. The serial numbers of the above-mentioned embodiments of the present invention are only for description and do not represent the advantages and disadvantages of the embodiments.

[0091] It should be noted that, in this article, the terms "include", "comprises" or any other variations thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device. In the absence of further restrictions, an element defined by the sentence "comprises a ..." does not exclude the existence of other identical elements in the process, method, article or device including the element.

[0092] In the several embodiments provided by the present invention, it should be understood that the disclosed devices and methods can be implemented in other ways. The device embodiments described above are only schematic. For example, the division of the units is only a logical function division. There may be other division methods in actual implementation, such as: multiple units or components can be combined, or can be integrated into another system, or some features can be ignored or not executed. In addition, the coupling, direct coupling, or communication connection between the components shown or discussed can be through some interfaces, and the indirect coupling or communication connection of the devices or units can be electrical, mechanical or other forms.

[0093] The units described above as separate components may or may not be physically separated, and the components displayed as units may or may not be physical units; they may be located in one place or distributed on multiple network units; some or all of the units may be selected according to actual needs to achieve the purpose of the embodiment of the present invention.

[0094] In addition, all functional units in the embodiments of the present invention may be integrated into one processing unit, or each unit may be separately used as a unit, or two or more units may be integrated into one unit; the above-mentioned integrated units may be implemented in the form of hardware or in the form of hardware plus software functional units.

[0095] The methods disclosed in the several method embodiments provided by the present invention can be arbitrarily combined without conflict to obtain new method embodiments.

[0096] The features disclosed in several method or device embodiments provided by the present invention can be arbitrarily combined without conflict to obtain new method embodiments or device embodiments.

[0097] The above is only an embodiment of the present invention, but the protection scope of the present invention is not limited thereto. Any person skilled in the art can easily think of changes or substitutions within the technical scope disclosed by the present invention, which should be included in the protection scope of the present invention. Therefore, the protection scope of the present invention should be based on the protection scope of the claims.

Claims

1. A SS-OCT system for synchronous imaging of the anterior and posterior segments of the eye with integrated optometry function, characterized in that: include: The optical coherence tomography (OCT) module uses a swept-frequency SS-OCT system to split the OCT scanning beam with a central wavelength of 1060 nanometers into an anterior segment imaging optical path for imaging the cornea and the entire lens and a posterior segment imaging optical path for imaging the retina through a 45° beam splitter, thereby achieving synchronous imaging of the entire eye, including the anterior and posterior segments, in one scanning cycle. The optometry module comprises a collimated light source, an annular aperture arranged in sequence along the optical path, a half-reflecting half-mirror and a focusing lens group arranged on one side of its reflecting surface, a second dichroic mirror and a CCD arranged behind the focusing lens group, and is used to dynamically measure the refractive state of the human eye by using an optometry method based on the collimated aperture and to provide real-time feedback of the refractive power; The automatic alignment module includes an oblique-axis camera, a coaxial camera, a first dichroic mirror, and an eye-receiving objective lens, and is used to use a triangulated positioning camera technology to automatically adjust the positions of the OCT module and the optometry module according to the positioning results, so as to ensure that the human eye to be tested is always in the best imaging position.

2. The system according to claim 1, characterized in that The OCT module includes: a swept frequency light source, a 90:10 fiber coupler, a first circulator, a reference arm module, a sample arm polarization controller, a reference arm polarization controller, a 50:50 fiber coupler, a balanced detector, an image signal acquisition card, a signal generator, a graphics workstation, a display, a second circulator, a sample arm module and a human eye to be tested; The sample arm module comprises a sample arm Y galvanometer, a sample arm X galvanometer, a sample arm optical fiber collimator, a first 45° beam splitter reflector, a second 45° beam splitter reflector, a posterior segment imaging flexion lens, a one-dimensional electric linear displacement platform, an eye-mounted objective lens, a posterior segment imaging optical path reflector group, and an anterior segment imaging optical path reflector group; The reference arm module includes a third 45° beam splitting reflector, a first reference arm corresponding to the anterior segment imaging optical path, a reference arm fiber optic collimator, a reference arm Y galvanometer, a reference arm X galvanometer, and a second reference arm corresponding to the posterior segment imaging optical path.

3. The system according to claim 2, characterized in that In the OCT module, a swept frequency light source is respectively input into the sample arm optical path and the reference arm optical path through a 90:10 optical fiber coupler; the light beam in the sample arm optical path is scanned by the sample arm optical fiber collimator, the sample arm X galvanometer, and the sample arm Y galvanometer in sequence, and then split by a first 45° beam splitting reflector, wherein the light beam irradiated to the upper reflection surface of the first 45° beam splitting reflector is focused to the retina through the posterior segment imaging optical path, and the light beam irradiated to the lower reflection surface of the first 45° beam splitting reflector is focused to the cornea through the anterior segment imaging optical path; The posterior segment imaging optical path comprises a posterior segment imaging optical path reflector group, a posterior segment imaging refractive lens, an upper reflective surface of a second 45° beam splitting reflector, and an eye-mounted objective lens; wherein the posterior segment imaging refractive lens is mounted on a one-dimensional electric linear displacement platform to move horizontally to achieve diopter adjustment; The anterior segment imaging optical path comprises an anterior segment imaging optical path reflector group, a lower reflective surface of a second 45° beam splitting reflector 23, and an eye-mounting objective lens.

4. The system according to claim 2, characterized in that The first reference arm includes a first beam returner and a first voice coil motor; the second reference arm includes a folding light path reflector, a second beam returner, and a second voice coil motor; the folding light path reflector is used to fold the light emitted by the reference arm collimator to the second beam returner; The first voice coil motor and the second voice coil motor are used to adjust the positions of the first beam returner and the second beam returner respectively, so as to adjust the optical path difference between the reference arm module and the sample arm module, and perform axial motion compensation for the physiological movement of the eye.

5. The system according to claim 2, characterized in that The reference arm Y galvanometer and the reference arm X galvanometer of the reference arm module, and the sample arm Y galvanometer and the sample arm X galvanometer of the sample arm module are controlled by a synchronous control signal to perform synchronous scanning with consistent scanning angles.

6. The system according to any one of claims 1 to 5, characterized in that: In the optometry module, the collimated light source passes through the annular aperture to form a collimated aperture, which passes through the semi-transparent and semi-reflective mirror group in turn. 、 The second dichroic mirror is guided into the pupil of the human eye to be tested, and the human eye causes the collimated aperture to form a diffusion ring on the retina, and the diffusion ring is reflected back to the optometry module through the human eye, and is reflected again to the focusing lens group through the semi-transparent and semi-reflective mirror group; The focusing lens group is responsible for dynamically adjusting the focal length to collect the reflection ring image reflected by the eye through the CCD; according to the change of the ring thickness of the reflection ring at different distances, the reflection image distance is determined, and then the diopter parameters of the human eye are solved through a calculation formula.

7. The system according to any one of claims 1 to 5, characterized in that: The oblique-axis camera in the automatic alignment module is arranged below the eye-mounted objective lens, and the optical axis is at a preset angle with the optical axis of the eye-mounted objective lens, so as to capture an oblique-angle image of the eye within a larger field of view and provide rough positioning information; The coaxial camera in the automatic alignment module is located behind the eye-mounted objective lens, and a forward coaxial image of the eye in a small field of view is captured through the first dichroic mirror. After the optical axis is refracted by the first dichroic mirror, it becomes coaxial with the optical axis of the eye-mounted objective lens, and is used to refine the positioning result and provide higher-precision eye alignment data. The first dichroic mirror is designed as a beam splitter that transmits 1060nm infrared light and reflects visible light, and is used to guide the eye image to the coaxial camera, while ensuring that there is no interference in the optical path to achieve precise imaging.

8. The system according to any one of claims 1 to 5, characterized in that: All components of the sample arm in the OCT module, all components of the optometry module, and all components of the automatic alignment module are encapsulated and fixed in an imaging probe, and the imaging probe is mounted on a three-dimensional electric displacement platform; when the system is in use, the position of the imaging probe is adjusted by moving the three-dimensional electric displacement platform to obtain the best imaging effect.

Images