37 results about "Retinal imaging" patented technology

The application discloses a diopter-adjustable and real-time retina imaging detection simulation eye, comprising: an emulated cornea, an emulated lens and an adjustable vitreous structure arranged in sequence along an optical axis; the adjustable vitreous structure comprises: a vitreous cavity filled with an emulated vitreous, a curved retina arranged at the end of the vitreous cavity, and a micrometer adjustment system for driving the curved retina to move forward and backward along the optical axis; the foveal region of the curved retina is integrated with an attenuation module and an imaging module, which are used for collecting a light spot image on the foveal region in real time; the simulation eye further comprises an analysis module electrically connected with the imaging module, and the analysis module is configured to process the collected light spot image to extract optical parameters on the curved retina.

Optical coherence tomography (OCT) data can be analyzed with neural networks trained on OCT data and known clinical outcomes to make more accurate predictions about the development and progression of retinal diseases, central nervous system disorders, and other conditions. The methods take 2D or 3D OCT data derived from different light source configurations and analyze it with neural networks that are trained on OCT images correlated with known clinical outcomes to identify intensity distributions or patterns indicative of different retina conditions. The methods have greater predictive power than traditional OCT analysis because the invention recognizes that subclinical physical changes affect how light interacts with the tissue matter of the retina, and these intensity changes in the image can be distinguishable by a neural network that has been trained on imaging data of retinas.

The application belongs to the technical field of vision care, and provides a kind of intelligent glasses, glasses box and vision training method, intelligent glasses include: frame mechanism;Lens mechanism, it includes left mirror unit, right mirror unit and pupil distance adjusting unit, left mirror unit, right mirror unit are connected with pupil distance adjusting unit to realize lens pupil distance adjusting function;Drive mechanism is connected with pupil distance adjusting unit to realize zoom vision training function.The intelligent glasses provided by the application is simple in appearance, light in quality, can replace daily ordinary corrective glasses for use, can improve the user's retinal imaging quality by adjusting the lens pupil distance, reduce the eye fatigue, at the same time, the lens can be driven to reciprocate to realize zoom vision training function, effectively exercise ciliary muscle, improve the accommodation ability and acuity of ciliary muscle, play the effect of preventing and treating myopia and amblyopia, the vibration is weak, avoid the phenomenon of dizziness and discomfort produced in the training process, improve the user experience and vision training effect of wearer.

A retinal camera and related methods of use are described. In an example, the retinal camera comprises a lens tube; a face rest shaped to steady a face of a user when the face is placed against the face rest; a light baffle positioned to conceal internal components of the retinal imaging system, wherein the light baffle defines a slit; and an alignment indicator positioned to be visible through the slit when an eye of the face is within an initial alignment zone of the retinal imaging system. In an example, the face rest defines a horizontal axis, and wherein the slit is parallel to the horizontal axis. In an example, the slit is positioned to align with a line between two eyes of the user when the face is placed against the face rest.

A low-cost line-field parallel swept-source optical coherence tomography (OCT) system suitable for home monitoring of diabetic retinopathy and other disease states including macular degeneration is disclosed. The system includes a tunable laser coupled to an interferometer and a line-scan detector, and a single-board computer configured to control laser tuning and acquire interference data. A fixation target display is positioned to project an image to a patient's eye, and is moved in discrete steps orthogonal to the projected OCT scanline to acquire multiple B-scans at different retinal positions without mechanical beam scanning. The fixation target movement enables cross-sectional or volumetric retinal imaging using a single fixed OCT scanline, reducing system complexity and cost. The single-board computer processes line-field interferograms into depth-resolved profiles, displays images, and controls fixation target positioning. The system enables early detection and monitoring of diabetic macular edema and other retinal complications in a compact, patient-operable configuration.

A compact confocal scanning laser ophthalmoscope comprising a MEMS scan mirror with a compact scan head, for use with small animal subjects. The scan head is connected to the source, detector and control electronics by flexible optical and electrical umbilicals and includes a zoom lens to provide both a wide field of view and high resolution imaging of the retina using a range of imaging modalities.

The invention discloses a spectacle lens and glasses, and relates to the technical field of myopia prevention and control. The spectacle lens comprises a lens body and a grid lattice structure, the lens body is provided with a central optical area arranged in the optical center of the lens body and a peripheral optical area arranged around the central optical area, and the grid lattice structure is arranged on the surface of the lens body and at least partially arranged in the peripheral optical area. The grid lattice structure comprises a plurality of discretely-distributed structural units and linear connecting parts for connecting every two adjacent structural units, the structural units are point-shaped protrusions or point-shaped grooves and used for forming nodes of the grid lattice structure, and the linear connecting parts are linear protrusions or linear grooves and used for connecting the adjacent structural units to form a grid layout. The grid lattice structure can generate a continuous and uniform scattering effect on light passing through the peripheral optical area, and the imaging contrast ratio of retina imaging can be effectively reduced, so that the growth of an eye axis is slowed down, and the development of myopia is effectively controlled.

Systems and relative method of monitoring the state of a subject's retinal disease employ remote based OCT imaging of a subject's retina. A method includes receiving optical coherence tomography (OCT) image data of a retina of a subject for each of a series of OCT imaging sessions of the retina. The OCT image data of the retina is processed to determine a series of measured extent values. Each of the one or more measured extent values is indicative of a respective extent of the retinal disease.

The utility model discloses an optical lens for myopia control and myopia glasses, comprising a front surface and a rear surface which are correspondingly arranged, at least one of the front surface and the rear surface is formed by overlapping a waveform surface topological structure with a base plane contour, the wave-shaped surface topological structure forms a smooth and continuous wave-shaped structure on the whole optical lens along the center of the optical lens to the radial direction. According to the utility model, a smoothly changing positive degree signal is formed on the surface of the optical lens, mutation in retina imaging is avoided, and on the basis of correcting myopia, the optical lens provides positive degree and provides a stable defocus signal in a peripheral visual field area, so that the growth of the retina can be stably inhibited, and the purpose of slowing down the myopia progress is achieved.

The invention discloses a point diffusion scattering lens film layer, and belongs to the technical field of lens film layers, the film layer is attached to the surface of a common single-light spectacle lens, and a plurality of point diffusion scattering microstructures are arranged on the film layer. The point diffusion scattering microstructure is innovatively introduced, the retina imaging contrast ratio is reduced, meanwhile, the visual experience and the application range are optimized, a more efficient and flexible solution is provided for myopia prevention and control, the film layer is easy to replace, the lens does not need to be replaced, and the expenditure cost is reduced.

Various implementations disclosed herein include devices, systems, and methods that track an eye characteristic (e.g., gaze direction, eye orientation, etc.). For example, an example process may include producing light that reflects off a retina of an eye, receiving an image of a portion of the retina from an image sensor, the image corresponding to a plurality of reflections of the light scattered from the retina of the eye, obtaining a representation of the eye corresponding to a first accommodative state, the representation representing at least some of the portion of the retina, and tracking an eye characteristic based on a comparison of the image of the portion of the retina with the representation of the eye.

The invention belongs to the technical field of ophthalmic optics, and relates to a microstructure myopia prevention and control lens and a design method thereof.The microstructure myopia prevention and control lens comprises a mother lens and a negative microlens array, and the mother lens comprises a central bright vision area and a regulation and control area; the negative micro lens array is arranged on the surface of the regulation and control area of the mother lens and comprises a plurality of even-order aspheric negative lenses arranged in an array mode, and the main curvature of each even-order aspheric negative lens changes from a negative value to a positive value from the center to the edge. According to the micro-structure lens with the even-order aspheric negative lens with the main curvature changing from the negative value to the positive value from the center to the edge, the light deflection angle of most of the area surrounding the center on the micro-structure can be increased, so that the aberration of medium-aperture and small-aperture light passing through the micro-structure is increased; the inhibition effect of the lens on the retina imaging contrast in a low-frequency band is further improved, the retina imaging contrast is reduced to be maximized under the condition of the same microstructure rise, and therefore the optimal effect of inhibiting the myopia progress is achieved.

Disclosed are example embodiments of a system of retinal three-dimensional (3D) imaging. The system of retinal 3D imaging includes an image sensor within a light path and a reimaging corrective optics module within the light path. The system of retinal 3D imaging also includes an objective lens in the light path and a baffle-and-illumination module in the light path. In an aspect, the reimaging corrective optics module is in front of the image sensor, the objective lens is in front of the reimaging corrective optics module, and the baffle-and-illumination module is between the objective lens and the reimaging corrective optics module.

A technique and apparatus for performing a visual field test on an eye includes sequentially presenting visual stimuli to the eye on a display. A first fixation target is presented on display in a first position offset from a center of the display, such as while presenting first visual stimuli on the display for measuring a visual function sensitivity of the eye contemporaneously with presenting the first fixation target. A response of the eye to the first visual stimuli is registered. A second fixation target is presented on the display in a second position offset from the center of the display, wherein the second position is different than the first position, such as while presenting second visual stimuli on the display for measuring a visual function sensitivity of the eye contemporaneously with presenting the second fixation target. A response of the eye to the second visual stimuli is registered.

This invention discloses a dual-optical-path whole-eye screening system and imaging method based on transient pulse illumination, belonging to the field of optical imaging and medical device technology. The system includes an illumination module, a beam splitting module, a fundus imaging optical path, an anterior segment imaging optical path, and an intelligent focusing algorithm module. The fundus imaging optical path utilizes a 4f relay lens group and a displacement compensation lens group to achieve retinal imaging; the anterior segment imaging optical path uses the red reflection principle to perform backlight imaging of the lens and anterior segment. The system, in conjunction with transient pulse illumination, under non-mydriatic semi-dark field conditions, utilizes the time difference of the human eye's pupillary constriction response to simultaneously acquire clear fundus and anterior segment images in a single exposure. This invention also proposes a dual-spectrum precise focusing algorithm based on a spatiotemporal hybrid attention mechanism. It extracts spatial features through a residual network and fuses temporal features using a long short-term memory network. Even with unknown individual refractive index distributions, it accurately predicts the optimal focus position for visible light based on near-infrared image sequences, solving the imaging quality problem caused by longitudinal chromatic aberration and reducing screening costs and operational complexity.

Systems and methods for generating a blood flow pattern of a target area of a subject in real time are provided. The approach involves receiving a video stream or sequence of multispectral images from a medical imaging device, such as an endoscope, retinal imaging device, or skin tissue sensor. The system identifies a region of interest (ROI) and decomposes the image data into pixel-level optical intensity data comprising individual spectral components, including visible (RGB), infrared (IR), or ultraviolet (UV) values. By analyzing temporal variations specifically calculating the statistical variance or standard deviation of these components the system detects pulsatile signals corresponding to blood flow. A real-time blood flow pattern map is generated and output to a display, often as a visual overlay on the original video stream, to reveal spatial perfusion characteristics, indicate tissue abnormalities, or distinguishing between superficial and deep blood flow.

The invention discloses an OCT (optical coherence tomography) device for optical retina imaging. An OCT apparatus for acquiring optical retinal imaging data, comprising: an optical system applying an optical stimulus confined to a partition of the retina of an eye, the position of the partition being controllable; an OCT imaging system that acquires OCT data from the retina; and a controller that: acquires a duration of a physiological response of the retina in the optical retinal imaging data to be acquired; acquiring target locations on the retina and using these target locations to control the optical system to apply optical stimuli to respective first partitions of the retina at respective target locations; controlling the OCT imaging system to acquire respective OCT data of a respective second partition of the retina for each first partition for a duration indicated by the first indicator, the second partition being stimulated by an optical stimulus applied to the first partition; and generating ORG data based on the acquired OCT data.

To obtain a high-quality image. **Solution**: The retinal imaging system includes an eyepiece lens assembly, an image sensor adapted to obtain a retinal image of an eye through the eyepiece lens assembly, and a controller communicatively coupled to the image sensor. The controller, when executed, causes the retinal imaging system to obtain a point of interest (POI) related to the eye or an indicator of the laterality of the eye, select an eye box position for the eye box of the retinal imaging system based at least in part on the POI or the laterality of the eye, and obtain a retinal image of the eye when the eye is determined to be positioned within the eye box. The eye box corresponds to a boundary region within a space defined with respect to the eyepiece lens assembly.

We are presenting a system, and an apparatus for fluorescence imaging, detection and spectroscopy. The device also comprises OCT (Optical Coherence Tomography) imaging. The device can be used for diagnosis, imaging, measurements, evaluation or therapy. The device can be used for ophthalmic imaging and / or diagnosis, or retinal imaging and / or diagnosis. The apparatus and system can be used for the measurement and imaging of the eyes of humans as well as the animals.

The invention discloses a field sequential display color separation suppression method and system based on human eye tracking, and belongs to the technical field of display. The method comprises the following steps: acquiring a fixation point coordinate and an eyeball movement velocity vector of an observer in real time through an eye movement tracking device, and synchronously analyzing a sub-field time sequence signal of a display system; constructing a motion prediction model containing a system delay parameter, performing time domain extrapolation on an eyeball trajectory by using an algorithm, and accurately calculating a fixation point prediction position of each monochromatic sub-field at an actual lightening moment; on the basis of a retina imaging stabilization principle, taking the starting moment of the current frame as a reference anchor point to generate a reverse geometric translation compensation amount; the original image of each sub-field is reconstructed, and the displacement vacancy is eliminated in combination with the overscanning edge compensation technology. And finally, the display terminal is driven strictly according to the time sequence, so that the sub-field rays lightened at different time are projected to the same physical area of the retina to realize imaging superposition. According to the method, color separation artifacts are inhibited from a physical mechanism, and the visual quality is remarkably improved.

The invention discloses an active retina projection display system, which belongs to the field of augmented reality (AR) near-to-eye display and comprises a light source module, an imaging module and a beam splitting and combining module which are sequentially arranged along a light path. The light source module comprises an active matrix display panel and an integrated collimating element array on the surface of the active matrix display panel, and is used for generating collimated light output for image display; the imaging module transmits the light beam to a system exit pupil through an accurate object image conjugate relation; and the light splitting and beam combining module is located at a specific light path position and is used for reflecting the image light beam and transmitting ambient light, so that the collimated light beam directly enters the human eyes and is imaged on the retina, and the collimated light beam is superposed with the ambient light path to realize augmented reality display. The system provided by the invention can realize large-range clear retina imaging, effectively alleviates visual convergence adjustment conflicts, and has the advantages of compact structure and high safety.

The invention relates to oblique transscleral illumination of an eye fundus with at least one physical point light source around the eye allowing for dark field imaging combined with optical coherence tomography imaging.

The invention relates to the technical field of vision detection, in particular to novel medical equipment for vision detection and a control method thereof. Determining that the to-be-detected child is located at a designated position, and triggering a detection program to start according to the age of the to-be-detected child Displaying a three-color sphere based on preset parameters, controlling the sphere to move based on a vision value locking algorithm, determining eyeball following times, and obtaining a vision value; on the basis of an amblyopia qualitative detection algorithm, controlling the sphere to move to obtain retinal imaging response delay time and child blinking frequency; based on the vision value, the retinal imaging response delay time and the child blinking frequency, a detection result is obtained through a child amblyopia detection algorithm model. According to the method, a vision value locking algorithm, an amblyopia qualitative detection algorithm and a child amblyopia detection algorithm model are adopted, the improved E word table quantitative logic and the improved OKN qualitative logic are fused through algorithms, quantitative and qualitative synchronous detection of child amblyopia is achieved, the detection efficiency is 2.7 times that of a traditional method, and the detection accuracy rate reaches 95% or above.

A compact line- or full-field optical coherence tomography (OCT) system designed for high-resolution retinal imaging with reduced artifacts employs quarter wave plates in both the sample and reference arms to manipulate the polarization state of light, effectively suppressing spurious reflections and coherence repeat artifacts. A symmetrical arrangement of, for example, Plössl eyepiece and camera objective lenses minimizes optical aberrations and maintains a flat imaging field despite the retina's curvature. The scanning galvanometer mirror is positioned at the conjugate plane of the patient's eye pupil and sized to act as an aperture stop. An adjustable eyepiece compensates for individual refractive errors, enhancing image clarity across a wide range of patients.

The application belongs to the technical field of eye optics, and relates to a microstructure myopia prevention lens and a design method thereof. The microstructure myopia prevention lens comprises a parent lens and a negative microlens array. The parent lens comprises a central clear area and a regulation area. The negative microlens array is arranged on the surface of the regulation area of the parent lens and comprises a plurality of even aspheric negative lenses arranged in an array. The main curvature of each even aspheric negative lens changes from a negative value to a positive value from the center to the edge. The microstructure lens with the even aspheric negative lens designed in the application can improve the light deflection angle of most areas around the center of the microstructure, increase the aberration of the medium and small aperture light passing through the microstructure, further improve the inhibition effect of the lens on the retinal imaging contrast in the low frequency band, realize the maximization of the retinal imaging contrast under the same microstructure sag, and thus achieve the best effect of inhibiting the progression of myopia.

A retinal camera and related methods of use are described. In an example, the retinal camera comprises a lens tube that moves along a first axis and a second axis to align with an eye to capture an image of the eye through the lens tube; and a face rest adapted to steady a head when capturing the image; and an adjustable curtain disposed inside the retinal camera to conceal internal components of the retinal camera from being visible through the face rest. In an example, the lens tube protrudes through the adjustable curtain. In an example, the adjustable curtain comprises a first adjustable mechanism that permits the lens tube to move along the first axis; and a second adjustable mechanism that permits the lens tube to move along the second axis

The present invention relates to a water-soluble compound for detecting beta-amyloid and a preparation method thereof. The compound of the present invention has excellent water solubility, and thus can provide a water-soluble preparation for detecting beta-amyloid. Therefore, the compound can be used as a composition for detecting beta-amyloid by retinal imaging.

A technique of imaging a retina includes acquiring a preliminary infrared (IR) image of the retina with a retinal camera system; determining an IR intensity of the preliminary IR image; determining a select power setting for a white light flash of the retinal camera system used to capture a subsequent color image of the retina after acquiring the preliminary IR image; and capturing the subsequent color image of the retina with the white light flash set to the select power setting. The determination of the select power setting is based on the IR intensity of the preliminary IR image and a correlation function that correlates IR intensities of IR images to red channel intensities in color retinal images.

Methods and systems for measuring hemoglobin concentration (cHb). A retinal tissue having blood vessels is illuminated by light including two isosbestic wavelengths (λ1,λ2). The isosbestic wavelengths(λ1,λ2) correspond to isosbestic points where oxy- and deoxyhemoglobin (HbIO2,Hb) have the same molar extinction coefficient. Measurements are collected of a plurality of backscattered reflection intensities (I(χb,λ1), I(xt,λ1), I(χb,λ2), I(xx,X2)). Preferably, the measurements are spectrally resolved at least for the two isosbestic wavelengths (λ1,λ2) and position-resolved for at least a blood vessel location (xb) coinciding with a selected blood vessel and a tissue location (xt) coinciding with the retinal tissue without blood vessel. The hemoglobin concentration (cHb) can be calculated based on a combination of the measurements at the two isosbestic wavelengths (λt,λ2).

Introduced here are approaches to generating an image with a fundus camera based on parameters determined through modeling of eye motion. The method captures a series of images to generate pupil position data over time. Using this data, the method determines a model for estimating pupil positions and predicts a time associated with a minimum pupil velocity. The method can estimate the pupil position at this time and generate a fundus camera configuration based on the position. The method can transmit a command to capture an image of the eye using the fundus camera configuration. By implementing these approaches, an imaging system can improve the quality of retinal imaging for patients with eye motion.