Reflection-type confocal scanning retina imaging system based on adaptive optics

An adaptive optics and confocal scanning technology, applied in the field of medical imaging diagnostic systems, can solve problems such as difficult to guarantee stability, low longitudinal resolution, unfavorable imaging in different bands, etc., to improve the range of clinical applications, improve longitudinal resolution, The effect of eliminating astigmatism

Active Publication Date: 2010-10-20
INST OF OPTICS & ELECTRONICS - CHINESE ACAD OF SCI
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Problems solved by technology

However, this system uses a camera as an imaging detector, which can only perform single-frame exposure at a time, and cannot track changes in fundus tissue in real time; secondly, the longitudinal resolution of this system is low, close to 300 microns, and it is difficult to distinguish different layers of the retina; finally , the system uses a transmission optical path, which is not conducive to imaging in different wavelength bands
[0006] In US Patent No. US 6,890,076B2, a confocal scanning retinal imaging system based on adaptive optics is introduced. This system uses a trial lens placed at the entrance pupil of the human eye to correct system ...

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  • Reflection-type confocal scanning retina imaging system based on adaptive optics
  • Reflection-type confocal scanning retina imaging system based on adaptive optics
  • Reflection-type confocal scanning retina imaging system based on adaptive optics

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Embodiment Construction

[0033] Such as figure 1 As shown, there are four processes in the actual operation of the system, the main optical path transmission process, the data acquisition and imaging process, the adaptive optics correction process and the subject-related process. Including a semiconductor laser light source 1, a plurality of reflective beam narrowing and expanding systems 11-18, a two-dimensional scanning galvanometer composed of an X-direction scanning galvanometer 23 and a Y-direction galvanometer 24, a Hartmann wavefront sensor 9, a deformation Mirror 22, a collection lens 27, a pinhole 4 and a photomultiplier tube 5, a photodetection system, a data acquisition and processing system 6, and an eye sight system 30. Wherein the six planes of the collimating mirror 21, the deforming mirror 22, the X-direction scanning galvanometer 23, the Y-direction scanning galvanometer 24, the trial lens 25 and the Hartmann front conjugate surface 26 are in conjugate positions.

[0034] (1) Main op...

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Abstract

The invention relates to a reflection-type confocal scanning retina imaging system based on adaptive optics, which can accurately obtain the high-resolution images of vital human eye retinae in real time and comprises a light source, a reflection-type beam shrinking and expanding system, a two-dimension scanning galvanometer, a Hartmann sensor, a deformable mirror, a photoelectric detection system, a data acquisition and processing system and a contraocular sighting target system. Lasers emitted from the light source are hit into human eye ground; light reflected from the eye ground returns along the original path, enters the photoelectric detection system and passes through the data acquisition and processing system to obtain the real-time images of the human eye ground. Simultaneously, an adaptive optics system comprising the Hartmann sensor and the deformable mirror can synchronously detect and correct human eye aberration, and thereby, the high resolution of the images is ensured.

Description

technical field [0001] The invention relates to a medical imaging diagnosis system for high-resolution imaging of the retina, in particular to a total reflection confocal scanning retinal imaging system based on adaptive optics and another eye target. Background technique [0002] Retinal images of the human eye are indispensable and important information in ophthalmology diagnosis and treatment. Both medical research and clinical studies have proved that diseases such as diabetes, arteriovenous thrombosis, hypertension, anemia, kidney disease, pregnancy-induced hypertension, and tumors can all be reflected in the microcirculation of the fundus, and abnormal metabolism of the fundus can lead to lesions in the fundus. Real-time tracking of topographic changes of the fundus retina will help in the early diagnosis and prevention of the above-mentioned physical diseases. In 1987, R.H.Webb applied the confocal scanning technology to the retinal imaging of the living human eye. H...

Claims

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Application Information

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IPC IPC(8): A61B3/12A61B3/15
Inventor 张雨东卢婧李昊史国华饶学军
Owner INST OF OPTICS & ELECTRONICS - CHINESE ACAD OF SCI
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