Positioning pipette tips with guide frame

By using a guide frame with position detection area and alignment device in laboratory automation equipment, the alignment error problem between the pipette tip and component port is solved, and a high-precision liquid pipetting operation is achieved.

CN119657253APending Publication Date: 2025-03-21TECAN TRADING CO LTD
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Patent Information

Application Number
CN202411297392.2
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Priority Date
2023-09-20
Filing Date
2024-09-18
Publication Date
2025-03-21

AI Technical Summary

Technical Problem

Existing laboratory automation equipment has alignment errors and coaxial errors when pipetting liquids to the ports of removable components, resulting in tip orifices not reaching the ports of components.

Method used

A guide frame is adopted, which includes a bottom side, a top side and an opening, and the top side has a position detection area. The position of the guide frame is determined by capacitance measurement, and the precise positioning of the guide frame and components is achieved using alignment devices such as permanent magnets and magnetic materials.

Benefits of technology

It effectively reduces the alignment error between the pipette tip and the component port, improves the accuracy and reliability of liquid pipetting, and ensures that small ports can also contact efficiently.

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Abstract

The invention relates to positioning a pipette tip with a guide frame. The guide frame for laboratory automation equipment comprises: a bottom side for placing the guide frame on a component of the laboratory automation equipment; a top side having a position detection area; and an opening for accessing the port of the component, the opening being arranged alongside the position detection area. The position detection region has two recesses, each having two straight edges arranged obliquely with respect to each other as seen from a viewing direction on the top side. The bottom side comprises alignment means for aligning the guide frame relative to the component, the alignment means comprising a base surface for contacting a top surface of the component and / or a guide surface for contacting a wall of the component.
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