Insecticidal composition and use thereof

Abstract

The present application relates to sanitary insecticide, in particular to a kind of insecticidal composition containing methoxy acrylate compound (Flupyroxystrobin) and methoxyfenozide and application thereof.The composition is methoxy acrylate compound and methoxyfenozide shown in formula I, wherein the weight ratio of methoxy acrylate compound and methoxyfenozide is 1:10~10:1;The present application processes Flupyroxystrobin and methoxyfenozide into wettable powder, water dispersible granule or suspension concentrate, reduces the use of organic solvent, is more friendly to environment, and has excellent lethal effect on public health pests.The compound insecticide is applied by retarding spraying mode, has remarkable synergistic effect in preventing and treating public health pests, can reduce the amount of pesticide application, save cost, delay the generation of pest resistance, and is widely applied in hotel, school, factory, family, farmer, breeding farm and public place etc.Formula I is

Description

TECHNICAL FIELD

[0001] The present application relates to a hygienic insecticide, in particular to an insecticidal composition containing a methoxy acrylate compound (Flupyroxystrobin) and methoprene and application thereof. BACKGROUND

[0002] Methoprene has contact and stomach toxicity, and has good knockdown activity; it also has the dual characteristics of inhibiting acetylcholinesterase and nerve axon, and can effectively control hygienic pests, especially cockroaches resistant to pyrethroid.

[0003] Flupyroxystrobin is the first methoxy acrylate insecticide, and its presumed mechanism of action is a Qo mitochondrial respiration inhibitor. By inhibiting the respiration of target pest mitochondria, it inhibits the energy synthesis of insects, and ultimately leads to the death of insects.

[0004] In the current external environment field, the long-term use of a large amount of single product in residual spraying products has led to a large resistance of pests such as mosquitoes, flies and cockroaches, and in recent years, the phenomenon of generally reduced efficacy has also appeared. Therefore, environmentally friendly and efficient pesticide compound varieties are needed to delay the development of hygienic pest resistance. SUMMARY

[0005] The technical problem to be solved by the present application is to provide an insecticidal composition containing a methoxy acrylate compound (Flupyroxystrobin) and methoprene and application thereof in view of the deficiencies in the prior art.

[0006] In order to achieve the above-mentioned purpose, the technical scheme adopted by the present application is as follows:

[0007] An insecticidal composition, the composition is a methoxy acrylate compound and methoprene shown in formula I, wherein the weight ratio of the methoxy acrylate compound and the methoprene is 1:10-10:1.

[0008] Formula I is

[0009] Preferably, the weight ratio of the methoxy acrylate compound and the methoprene is 1:5-5:1.

[0010] An insecticide, the insecticide takes the composition as an active ingredient and an auxiliary material; wherein the active ingredient accounts for 10%-50% of the mass of the preparation.

[0011] The dosage form of the insecticide is wettable powder, water dispersible granule or suspension.

[0012] The wettable powder is 5-30% of the insecticidal composition containing Flupyroxystrobin and Spinetoram, 1-10% of the dispersing agent, 1-5% of the wetting agent, and the filler is supplemented to 100%.

[0013] The water dispersible granule is 10-50% of the compound insecticidal composition containing Flupyroxystrobin and Spinetoram, 1-10% of the dispersing agent, 1-5% of the wetting agent, 1-10% of the disintegrating agent, 0.1-1% of the binder, and the filler is supplemented to 100%.

[0014] The suspension concentrate is 5-30% of the compound insecticidal composition containing Flupyroxystrobin and Spinetoram, 1-10% of the dispersing agent, 1-5% of the wetting agent, 0.1-1% of the thickening agent, 0.1-1% of the preservative, 3-10% of the antifreeze agent, 0.1-0.5% of the defoaming agent, and deionized water is supplemented to 100%.

[0015] The wettable powder is prepared by the following method: according to the proportion, the insecticidal composition containing Flupyroxystrobin and Spinetoram, the wetting agent, the dispersing agent and the filler are added into the food processor and mixed uniformly, and then the mixture is crushed in the jet mill to obtain the wettable powder.

[0016] The water dispersible granule is prepared by the following method: according to the proportion, the insecticidal composition containing Flupyroxystrobin and Spinetoram, the wetting agent, the dispersing agent, the disintegrating agent, the binder and the filler are added into the food processor and mixed uniformly, and then the mixture is crushed in the jet mill, the powder is put into a beaker and added with appropriate amount of water, stirred and kneaded, extruded and granulated by the granulator, and dried to obtain the water dispersible granule.

[0017] The suspension concentrate is prepared by the following method: according to the proportion, the insecticidal composition containing Flupyroxystrobin and Spinetoram, the wetting agent, the dispersing agent, the antifreeze agent, the preservative, the defoaming agent and deionized water are added into a beaker and mixed uniformly, and then the mixture is transferred to a sand mill, zirconium oxide beads are added into the sand mill, and the mixture is ground for 2-3h, the thickening agent is added and the mixture is ground for another 0.5h, so that the particle size D 95 is controlled to be less than 5 microns, the zirconium oxide beads are removed by filtration, and the suspension concentrate is obtained.

[0018] The dispersing agent is selected from any one of methylene bis naphthalene sulfonic acid sodium, sodium lignosulfonate, alkylphenol polyoxyethylene ether formaldehyde condensate, naphthalene sulfonic acid sodium, sodium alkylbenzene sulfonate, naphthalene sulfonic acid formaldehyde condensate sodium salt, alkylphenol polyoxyethylene ether, polyarylphenyl ether ammonium phosphate salt, succinic acid bis ester sodium salt, and phosphoric acid triethanolamine salt, or a mixture of two or more thereof in any proportion.

[0019] The wetting agent is selected from any one of sodium alkyl polyoxyethylene ether succinate sulfonate, sodium dihydroxydiphenyl sulfonate, phenylethyl phenol polyoxyethylene ether phosphate, sodium alkyl sulfate, sodium fatty acid ester sulfate, sodium naphthalene sulfonate, sodium dodecyl sulfate, laopen powder BX, sodium dodecyl benzene sulfonate, or a mixture of two or more thereof in any ratio.

[0020] The filler is selected from any one of kaolin, pottery clay, corn starch, attapulgite, light calcium carbonate, diatomite, bentonite, or a mixture of two or more thereof in any ratio.

[0021] The disintegrant is selected from any one of sodium chloride, ammonium chloride, ammonium sulfate, sodium carbonate, sodium carboxymethyl starch, sodium sulfate.

[0022] The binder is selected from any one of methyl cellulose, polyvinyl pyrrolidone, polyvinyl alcohol, polyethylene glycol, sodium carboxymethyl cellulose.

[0023] The thickening agent is selected from any one of xanthan gum, sodium alginate, magnesium aluminum silicate, chitin, guar gum, or a mixture of two or more thereof in any ratio.

[0024] The preservative is selected from any one of potassium sorbate, p-hydroxybenzoic acid, casson, benzisothiazolinone.

[0025] In the above technical solution, the antifreeze is selected from any one of ethylene glycol, propylene glycol, glycerol, urea.

[0026] In the above technical solution, the defoaming agent is selected from any one of dipalmitoyl ethylenediamine, triocetyl phosphate, dimethyl silicone oil, cetyl alcohol, glyceryl ricinoleate.

[0027] The application of the composition or preparation in the prevention and control of public health pests.

[0028] The composition or insecticide is applied in the form of residual spraying when preventing and controlling public health pests, and is sprayed on the surfaces of walls, doors, windows, ceilings and home furnishings after wettable powder is diluted with water at 100-200 times, water dispersible granule is diluted with water at 100-200 times, and suspension concentrate is diluted with water at 100-200 times.

[0029] The public health pests refer to mosquitoes, flies, cockroaches, fleas, and the application sites include hotels, schools, factories, families, farmers, breeding farms and public places.

[0030] The advantages of the technical solution of the present application are:

[0031] The insecticide provided by the application is prepared by compounding Flupyroxystrobin and Spinetoram into wettable powder, water dispersible granule or suspension concentrate, reduces the use of organic solvents, is more friendly to the environment, has a significant synergistic effect on the prevention of public health pests, can reduce the amount of pesticide application, save costs, and delay the generation of pest resistance. DETAILED DESCRIPTION

[0032] The application will be described in detail below in combination with specific examples, and the specific implementation of the technical solutions of the application will be described in detail below, but the application is not limited to the following description, and the percentages in the following examples refer to weight percentages unless otherwise specified.

[0033] The application compounds Flupyroxystrobin and Spinetoram, which not only improves the prevention effect on public health pests and delays the generation of public health pest resistance, but also reduces the harm of organic solvents to the environment and is more friendly to the environment; the public health insecticidal composition has good insecticidal effect, synergistic effect, and is not prone to resistance.

[0034] Application Example 1: Determination of the Co-toxicity Coefficient of Flupyroxystrobin and Spinetoram to Culex pipiens pallens Test target: Culex pipiens pallens Test method: The activity of Culex pipiens pallens was determined by the drop method according to NY / T 1154.1-2006, Pesticide Indoor Biological Test Guidelines Part 1: Contact Activity Test.

[0035] The data were calculated by linear weighted regression method to obtain the median lethal dose LD 50 , and the co-toxicity coefficient was calculated according to the method of Sun Yunpei.

[0036] Table 1 Co-toxicity coefficient determination of Flupyroxystrobin and Spinetoram (for Culex pipiens pallens)

[0037]

[0038]

[0039] As shown in Table 1, when the compounding ratio of Flupyroxystrobin and Spinetoram is 1:10-10:1, the co-toxicity coefficient for Culex pipiens pallens is greater than 120, and when the compounding ratio is 1:5-5:1, the co-toxicity coefficient is more than 130, which has a significant synergistic effect.

[0040] Preparation Example 1: 22% Flupyroxystrobin·Spinetoram wettable powder

[0041] Flupyroxystrobin 2%, Spinosad 20%, Sodium lignosulfonate 4%, Methylene bis-naphthalene sulfonic acid sodium salt 6%, Alkylphenol polyoxyethylene ether formaldehyde condensate naphthalene sulfonic acid sodium salt 3%, Diatomite 20%, Kaolin to 100%.

[0042] The formulation materials were mixed uniformly, and then were crushed by a super micro jet crusher to prepare 22% Flupyroxystrobin·Spinosad wettable powder.

[0043] Preparation Example 2: 27% Flupyroxystrobin·Spinosad wettable powder

[0044] Flupyroxystrobin 3%, Spinosad 24%, Alkylphenol polyoxyethylene ether formaldehyde condensate 8%, Naphthalene sulfonic acid sodium salt 1%, Sodium dodecyl sulfate 3%, Pottery clay 25%, Kaolin to 100%.

[0045] The formulation materials were mixed uniformly, and then were crushed by a super micro jet crusher to prepare 27% Flupyroxystrobin·Spinosad wettable powder.

[0046] Preparation Example 3: 30% Flupyroxystrobin·Spinosad wettable powder

[0047] Flupyroxystrobin 5%, Spinosad 25%, Naphthalene sulfonic acid sodium salt 2%, Alkylbenzene sulfonic acid sodium salt 5%, Dihydroxydiphenyl sulfonic acid sodium salt 5%, Corn starch to 100%.

[0048] The formulation materials were mixed uniformly, and then were crushed by a super micro jet crusher to prepare 30% Flupyroxystrobin·Spinosad wettable powder.

[0049] Preparation Example 4: 5% Flupyroxystrobin·Spinosad wettable powder

[0050] Flupyroxystrobin 2.5%, Spinosad 2.5%, Naphthalene sulfonic acid formaldehyde condensate sodium salt 6%, Phenylethyl phenol polyoxyethylene ether phosphate 4%, Bentonite 25%, Light calcium carbonate to 100%.

[0051] The formulation materials were mixed uniformly, and then were crushed by a super micro jet crusher to prepare 5% Flupyroxystrobin·Spinosad wettable powder.

[0052] Preparation Example 5: 21% Flupyroxystrobin·Spinosad wettable powder

[0053] Flupyroxystrobin 17.5%, Spinosad 3.5%, alkylphenol polyoxyethylene ether 7%, sodium alkylnaphthalenesulfonate 2%, sodium fatty acid ester sulfate 2%, attapulgite to 100%.

[0054] The formulation materials were mixed uniformly, and then were crushed by a super micro air flow crusher to prepare 21% Flupyroxystrobin · Spinosad wettable powder.

[0055] Preparation Example 6: 18% Flupyroxystrobin · Spinosad wettable powder

[0056] Flupyroxystrobin 16%, Spinosad 2%, polyarylphenyl ether phosphoric acid ammonium salt 5%, succinic acid bis ester sulfonate sodium salt 5%, alkyl polyoxyethylene ether succinate sodium salt 2%, sodium dodecylbenzenesulfonate 2%, bentonite 10%, kaolin to 100%.

[0057] The formulation materials were mixed uniformly, and then were crushed by a super micro air flow crusher to prepare 18% Flupyroxystrobin · Spinosad wettable powder.

[0058] Preparation Example 7: 11% Flupyroxystrobin · Spinosad wettable powder

[0059] Flupyroxystrobin 10%, Spinosad 1%, polyarylphenyl ether phosphoric acid ammonium salt 5%, succinic acid bis ester sulfonate sodium salt 5%, Laka powder BX 2%, sodium dodecylbenzenesulfonate 2%, bentonite 10%, kaolin to 100%.

[0060] The formulation materials were mixed uniformly, and then were crushed by a super micro air flow crusher to prepare 11% Flupyroxystrobin · Spinosad wettable powder.

[0061] Preparation Example 8: 44% Flupyroxystrobin · Spinosad water dispersible granules

[0062] Flupyroxystrobin 4%, Spinosad 40%, sodium lignosulfonate 6%, naphthalene sulfonic acid formaldehyde condensate sodium salt 4%, sodium dodecyl sulfate 5%, sodium chloride 10%, methyl cellulose 0.5%, kaolin to 100%.

[0063] The formulation materials were mixed uniformly, and then were crushed by a super micro air flow crusher, and were kneaded with a small amount of water, and then were granulated and dried in a rotary granulator to prepare 44% Flupyroxystrobin · Spinosad water dispersible granules.

[0064] Flupyroxystrobin 5%, chlorfenapyr 40%, alkylphenol polyoxyethylene ether formaldehyde condensate 10%, fatty acid ester sodium sulfate 1%, pull-apart powder BX 2%, ammonium chloride 8%, polyvinylpyrrolidone 1%, clay 10%, corn starch to 100%.

[0065] The formula was mixed uniformly, and then was crushed by a super micro air flow crusher, kneaded with a small amount of water, and then was granulated and dried in a rotary granulator to prepare 45% Flupyroxystrobin · chlorfenapyr water dispersible granules.

[0066] Flupyroxystrobin 6%, chlorfenapyr 30%, sodium lignosulfonate 9%, alkyl sodium sulfate 4%, ammonium sulfate 9%, polyvinyl alcohol 0.6%, attapulgite to 100%.

[0067] The formula was mixed uniformly, and then was crushed by a super micro air flow crusher, kneaded with a small amount of water, and then was granulated and dried in a rotary granulator to prepare 36% Flupyroxystrobin · chlorfenapyr water dispersible granules.

[0068] Flupyroxystrobin 5%, chlorfenapyr 5%, methylene bis naphthalene sulfonic acid sodium 5%, alkyl benzene sulfonic acid sodium 3%, dodecyl benzene sulfonic acid sodium 1%, dodecyl sodium sulfate 2%, sodium carbonate 10%, polyethylene glycol 0.1%, diatomite to 100%.

[0069] The formula was mixed uniformly, and then was crushed by a super micro air flow crusher, kneaded with a small amount of water, and then was granulated and dried in a rotary granulator to prepare 10% Flupyroxystrobin · chlorfenapyr water dispersible granules.

[0070] Flupyroxystrobin 42%, chlorfenapyr 8%, alkylphenol polyoxyethylene ether formaldehyde condensate 1%, methylene bis naphthalene sulfonic acid sodium 6%, alkyl naphthalene sulfonic acid sodium 5%, sodium carboxymethyl starch 6%, carboxymethyl cellulose 0.5%, corn starch 20%, attapulgite to 100%.

[0071] The formula was mixed uniformly, and then was crushed by a super micro air flow crusher, kneaded with a small amount of water, and then was granulated and dried in a rotary granulator to prepare 50% Flupyroxystrobin · chlorfenapyr water dispersible granules.

[0072] Flupyroxystrobin 16%, Spinosad 2%, Sodium Sulfosuccinic Acid Dibutyl Ester 5%, Sodium Methylene Bis-naphthalene Sulfonate 4%, Lai Kai Powder BX 5%, Sodium Sulfate 10%, Polyvinyl Alcohol 0.2%, Kaolin up to 100%. The formula materials are mixed uniformly, and then are crushed by a super micro air flow crusher, kneaded with a small amount of water, and then are granulated and dried in a rotary granulator to prepare 18% Flupyroxystrobin·Spinosad water dispersible granules. Preparation Example 14: 11% Flupyroxystrobin·Spinosad water dispersible granules

[0073] Flupyroxystrobin 10%, Spinosad 1%, Sodium Lignosulfonate 10%, Sodium Dodecyl Sulfate 4%, Sodium Sulfate 5%, Sodium Carboxymethyl Cellulose 0.3%, Corn Starch up to 100%.

[0074] The formula materials are mixed uniformly, and then are crushed by a super micro air flow crusher, kneaded with a small amount of water, and then are granulated and dried in a rotary granulator to prepare 11% Flupyroxystrobin·Spinosad water dispersible granules. Preparation Example 15: 11% Flupyroxystrobin·Spinosad suspension

[0075] Flupyroxystrobin 1%, Spinosad 10%, Phosphonate Triethanolamine Salt 3%, Sodium Methylene Bis-naphthalene Sulfonate 5%, Sodium Dihydroxydiphenyl Sulfonate 2%, Sodium Naphthalene Sulfonate 1%, Xanthan Gum 0.2%, Magnesium Aluminum Silicate 0.8%, Potassium Sorbate 0.5%, Ethylene Glycol 10%, Cetyl Alcohol 0.3%, Deionized Water up to 100%. The formula materials are mixed uniformly, and are sand milled by a sand mill until the particle size is less than 5 microns to prepare 11% Flupyroxystrobin·Spinosad suspension.

[0076] Preparation Example 16: 13.5% Flupyroxystrobin·Spinosad suspension

[0077] Flupyroxystrobin 1.5%, Spinosad 12%, Sodium Sulfosuccinic Acid Dibutyl Ester 10%, Alkylphenol Polyoxyethylene Ether Formaldehyde Condensate Sodium Naphthalene Sulfonate 5%, Xanthan Gum 0.2%, Sodium Alginate 0.5%, p-Hydroxybenzoic Acid 1%, Propylene Glycol 5%, Dimethyl Silicone Oil 0.1%, Deionized Water up to 100%.

[0078] The formula materials are mixed uniformly, and are sand milled by a sand mill until the particle size is less than 5 microns to prepare 13.5% Flupyroxystrobin·Spinosad suspension.

[0079] Preparation Example 17: 30% Flupyroxystrobin·Spinosad suspension

[0080] Flupyroxystrobin 5%, Spinosad 25%, polyarylphenyl ether ammonium phosphate 1%, methylene bis-naphthalene sulfonic acid sodium 5%, dihydroxydiphenyl sulfonic acid sodium 2%, sodium dodecyl benzene sulfonate 3%, chitin 0.1%, casein 0.3%, glycerol 5%, dipalmitoyl ethylenediamine 0.5%, deionized water to 100%. The formulation materials are mixed uniformly, and are ground by a sand mill until the particle size is less than 5 microns to prepare 30% Flupyroxystrobin·Spinosad suspension concentrate.

[0081] Preparation Example 18: 5% Flupyroxystrobin·Spinosad Suspension Concentrate

[0082] Flupyroxystrobin 2.5%, Spinosad 2.5%, alkylphenol polyoxyethylene ether 5%, sodium lignosulfonate 3%, benzyl phenol polyoxyethylene ether phosphate 3%, guar gum 0.3%, magnesium aluminum silicate 0.7%, benzisothiazolinone 0.1%, urea 3%, glyceryl ricinoleate 0.5%, deionized water to 100%. The formulation materials are mixed uniformly, and are ground by a sand mill until the particle size is less than 5 microns to prepare 5% Flupyroxystrobin·Spinosad suspension concentrate.

[0083] Preparation Example 19: 9% Flupyroxystrobin·Spinosad Suspension Concentrate

[0084] Flupyroxystrobin 7.5%, Spinosad 1.5%, sodium lignosulfonate 10%, sodium alkyl naphthalene sulfonate 4%, naphthalene sulfonic acid sodium 1%, xanthan gum 0.3%, potassium sorbate 0.5%, propylene glycol 8%, dimethyl silicone oil 0.3%, deionized water to 100%.

[0085] The formulation materials are mixed uniformly, and are ground by a sand mill until the particle size is less than 5 microns to prepare 9% Flupyroxystrobin·Spinosad suspension concentrate.

[0086] Preparation Example 20: 27% Flupyroxystrobin·Spinosad Suspension Concentrate

[0087] Flupyroxystrobin 24%, Spinosad 3%, naphthalene sulfonic acid formaldehyde condensate sodium salt 8%, benzyl phenol polyoxyethylene ether phosphate 3%, sodium alginate 0.1%, magnesium aluminum silicate 0.5%, casein 0.1%, ethylene glycol 3%, triocetyl phosphate 0.5%, deionized water to 100%.

[0088] The formulation materials are mixed uniformly, and are ground by a sand mill until the particle size is less than 5 microns to prepare 27% Flupyroxystrobin·Spinosad suspension concentrate.

[0089] Preparation Example 21: 5.5% Flupyroxystrobin·Chinomethionat SC

[0090] Flupyroxystrobin 5%, Chinomethionat 0.5%, Sodium Alkylbenzenesulfonate 2%, Phosphoric acid ester triethanolamine salt 6%, Sodium Naphthalene Sulfonate 5%, Xanthan Gum 0.3%, Benzisothiazolinone 0.2%, Urea 4%, Dimethyl Silicone Oil 0.1%, Deionized Water to 100%.

[0091] Mix the ingredients evenly, and pass through a sand mill for sanding until the particle size is less than 5 microns to obtain 5.5% Flupyroxystrobin·Chinomethionat SC.

[0092] Application Example 2: Indoor retention efficacy test for controlling mosquitoes and flies

[0093] Housefly, 3rd to 4th day post-emergence adults, half male and half female;

[0094] Test method: retention spray test according to GB / T 13917.1-2009;

[0095] Test treatment: the total concentration of active ingredients of Preparation Examples 1, 5, 8, 12, 15, and 19 is diluted to 500 mg / L; Control Sample 1: 10% Flupyroxystrobin WP is diluted to 500 mg / L;

[0096] Control Sample 2: 10% Chinomethionat WP is diluted to 500 mg / L;

[0097] Test results:

[0098] Table 2 Efficacy test of Preparation Examples 1, 5, 8, 12, 15, and 19 against mosquitoes and flies

[0099]

[0100] As can be seen from Table 2, the knockdown effect of Preparation Examples 1, 5, 8, 12, 15, and 19 on Culex pipiens pallens and Musca domestica is better than that of the control sample single agent sample, and the mortality rate is also better than that of the control sample single agent sample. It can be seen that Flupyroxystrobin and Chinomethionat have good control effect on Culex pipiens pallens and Musca domestica when used in retention spray mode.

[0101] Application Example 3: Indoor retention efficacy test for controlling cockroaches

[0102] Test method: retention spray test according to GB / T 13917.1-2009;

[0103] Test treatment: The total concentration of active ingredients in formulations 2, 6, 9, 13, 18, and 20 was diluted to 500 mg / L; control sample 1 was diluted to 500 mg / L with 10% Flupyroxystrobin wettable powder.

[0104] Control sample 2: 10% oxadiazon wettable powder diluted to 500 mg / L;

[0105] Experimental results:

[0106] Table 3 shows the efficacy trials of formulation examples 2, 6, 9, 13, 18, and 20 against the German cockroach.

[0107] Treatment Name 0.5h Knockdown 1h Knockdown 2h Knockdown 72h Mortality Formulation Example 2 53.3％ 80％ 100％ 100％ Formulation Example 6 50％ 76.7％ 100％ 100％ Formulation Example 9 46.7％ 80％ 100％ 100％ Formulation Example 13 50％ 80％ 100％ 100％ Formulation Example 18 46.7％ 83.3％ 100％ 100％ Formulation Example 20 43.3％ 86.7％ 100％ 100％ Control 1 13.3％ 33.7％ 80％ 80％ Control 2 23.3％ 46.7％ 86.7％ 86.7％

[0108] As shown in Table 3, formulations 2, 6, 9, 13, 18, and 20 showed significant knockdown effects against German cockroaches within 0.5 hours, far exceeding controls 1 and 2. Furthermore, the knockdown rate against German cockroaches reached 100% within 2 hours, also better than controls 1 and 2. The 72-hour mortality rate of formulations 2, 6, 9, 13, 18, and 20 against German cockroaches was better than the control single-agent samples. This demonstrates that the combination of Flupyroxystrobin and oxadiazon, applied via residual spraying, provides excellent control of German cockroaches.

[0109] Application Example 4: Indoor Residual Efficacy Test of Flea Control

[0110] Experimental target: Indo-rat flea, 3-10 day old adults, half male and half female;

[0111] Test method: Refer to GB / T 13917.1-2009 for residual spraying test;

[0112] Test treatment: The total concentration of active ingredients in formulations 3, 7, 10, 14, 19, and 21 was diluted to 500 mg / L; control sample 1 was diluted with 10% Flupyroxystrobin wettable powder to 500 mg / L.

[0113] Control sample 2: 10% oxadiazon wettable powder diluted to 500 mg / L;

[0114] Experimental results:

[0115] Table 4. Efficacy tests of formulation examples 3, 7, 10, 14, 19, and 21 against *Rhizoctonia solani*.

[0116] Treatment Name 0.5h Knockdown 1h Knockdown 24h Mortality Formulation Example 3 78％ 100％ 100％ Formulation Example 7 80％ 100％ 100％ Formulation Example 10 76％ 100％ 100％ Formulation Example 14 74％ 100％ 100％ Formulation Example 19 78％ 100％ 100％ Formulation Example 21 76％ 100％ 100％ Control 1 36％ 74％ 70％ Control 2 40％ 82％ 80％

[0117] As shown in Table 4, the preparation examples 3, 7, 10, 14, 19, 21 have obvious knockdown effect on Xenopsylla cheopis at 0.5h, which is much better than the control samples 1 and 2, the preparation examples 3, 7, 10, 14, 19, 21 have 100% knockdown rate on Xenopsylla cheopis at 1h, which are all better than the control samples 1 and 2; the preparation examples 3, 7, 10, 14, 19, 21 have better 24h mortality rate on Xenopsylla cheopis than the control samples 1 and 2. It can be seen that the compound of Flupyroxystrobin and Spinetoram has good control effect on Xenopsylla cheopis by the way of residual spraying.

[0118] Application Example 5: Residual efficacy test of three different absorption contact surfaces Test target: Culex pipiens pallens, female adult of 3rd to 5th day after emergence without blood sucking;

[0119] Musca domestica, adult of 3rd to 4th day after emergence, half male and half female;

[0120] Blattella germanica, adult of 10th to 15th day, half male and half female;

[0121] Xenopsylla cheopis, adult of 3rd to 10th day, half male and half female;

[0122] Test method: refer to GB / T 13917.1-2009, residual spraying test, test once in 15 days, and evaluate according to the duration (d) of 24h (72h for cockroaches) mortality rate of more than 70%.

[0123] Test equipment board surface: non-absorbing surface-glass surface, A level for duration of more than 90d, and B level for duration of more than 60d;

[0124] Semi-absorbing surface-varnish surface, A level for duration of more than 60d, and B level for duration of more than 45d;

[0125] Absorbing surface-plaster surface (for mosquitoes, flies and fleas), cement surface (for cockroaches), A level for duration of more than 45d, and B level for duration of more than 30d;

[0126] Test treatment: the total concentration of active ingredients of the preparation examples 4, 11 and 18 are all diluted to 500mg / L;

[0127] Control sample 1: 10% Flupyroxystrobin wettable powder diluted to 500mg / L;

[0128] Control sample 2: 10% Spinetoram wettable powder diluted to 500mg / L;

[0129] Test results:

[0130] Table 5 Residual efficacy test of the preparation examples 4, 11 and 18 on non-absorbing surface (glass surface)

[0131]

[0132] Table 6 Retention efficacy test of formulation examples 4, 11, 18 on semi-absorbing surface (varnish surface)

[0133]

[0134]

[0135] Table 7 Retention efficacy test of formulation examples 4, 11, 18 on absorbing surface (white lime surface / cement surface)

[0136]

[0137]

[0138] From the test results in the above table, it can be seen that the formulation examples 4, 11, 18 of the present application have a duration rating of A level for testing Culex pipiens pallens, Musca domestica, Blattella germanica and Xenopsylla cheopis, while some of the targets in the control group have a duration of B level. The comprehensive control effect of the present application on different targets of three different absorbing contact surfaces is better than that of the control group, and the retention effect is better than that of the control group.

[0139] Application Example 6: Comparative test of outdoor efficacy for controlling flies

[0140] Test target: flies Test method: select the wall and ground of the breeding farm building as the test object and divide the area, spray the pesticide on the surface of the wall and ground, and record the fly density reduction rate after 1 day, 2 days, 3 days of each treatment group;

[0141] Test treatment: dilute formulation examples 2, 9, 16 by 100 times, and the dosage is 20 mg of active ingredient / m 2 ;

[0142] Control sample 3: commercially available 10% lambda-cyhalothrin wettable powder diluted by 100 times, and the dosage is 20 mg of active ingredient / m 2 ;

[0143] Control sample 4: commercially available 6% lambda-cyhalothrin+4% propoxur suspension concentrate diluted by 100 times, and the dosage is 20 mg of active ingredient / m 2 ;

[0144] Test results:

[0145] Table 8 Comparative test of outdoor efficacy of formulation examples 2, 9, 16 on flies

[0146]

[0147]

[0148] The results show that the preparation examples 2, 9 and 16 of the present application have obvious fly control effect, the density reduction rate is more than 50% at 1d, and the density reduction rate is more than 95% at 3d, which are better than the control samples 3 and 4. It can be seen that the retention spraying mode of Flupyroxystrobin and Spinetoram has good control effect.

[0149] The above examples are only for illustrating the technical concept and technical features of the present application, and cannot limit the protection scope of the present application. Any equivalent transformation or modification according to the essence of the present application should be covered in the protection scope of the present application.

Claims

1. An insecticidal composition, characterized by comprising, The composition is a methoxy acrylate compound and chlorfenapyr of formula I, wherein the weight ratio of the methoxy acrylate compound and chlorfenapyr is 1:10-10:

1. Formula I is .

2. The insecticidal composition according to claim 1, characterized by, The weight ratio of the methoxy acrylate compound and chlorfenapyr is 1:5-5:

1.

3. An insecticide, characterized by: The insecticide is an active ingredient and adjuvant of the composition of claim 1, wherein the active ingredient accounts for 10%-50% of the mass of the preparation.

4. The insecticide of claim 3, wherein: The insecticide is in the form of wettable powder, water dispersible granule or suspension concentrate.

5. The insecticide according to claim 3 or 4, characterized in that: The wettable powder comprises 5%-30% of the insecticidal composition containing Flupyroxystrobin and chlorfenapyr, 1%-10% of dispersant, 1%-5% of wetting agent, and fillers to make up 100%.

6. The insecticide of claim 3 or 4, wherein: The water dispersible granule comprises 10%-50% of the insecticidal composition containing Flupyroxystrobin and chlorfenapyr, 1%-10% of dispersant, 1%-5% of wetting agent, 1%-10% of disintegrant, 0.1%-1% of binder, and fillers to make up 100%.

7. The insecticide of claim 3 or 4, wherein: The suspension concentrate comprises 5%-30% of the insecticidal composition containing Flupyroxystrobin and chlorfenapyr, 1%-10% of dispersant, 1%-5% of wetting agent, 0.1%-1% of thickening agent, 0.1%-1% of preservative, 3%-10% of antifreezing agent, 0.1%-0.5% of defoaming agent, and deionized water to make up 100%.

8. The use of a pesticidal composition according to claim 1 or a pesticide according to claim 3, characterized in that: The insecticidal composition or insecticide is used for preventing and treating public health pests.

9. Use according to claim 8, characterized in that, The insecticidal composition or insecticide is used for preventing and treating public health pests in the form of residual spraying, wherein the wettable powder is diluted with water at 100-200 times, the water dispersible granule is diluted with water at 100-200 times, and the suspension concentrate is diluted with water at 100-200 times, and then sprayed on walls, doors, windows, ceilings and household surfaces.

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