Preparation method, device and product of articular surface cartilage defect metal prosthesis

Abstract

The invention discloses a method, a device and a product for preparing a metal prosthesis for articular surface cartilage defect, which are characterized in that on the basis of the traditional metal prosthesis, an embedding anchoring part is additionally arranged between the contact surfaces of the metal prosthesis and a patient joint, so that the connection between the metal prosthesis and the patient joint is reinforced through the embedding anchoring part; meanwhile, the 3D printing technology is used for machining the metal prosthesis with the high complex structure, in this way, the machining precision can be guaranteed, and therefore the embedded anchoring part obtained through machining can be better attached to the joint; therefore, the non-cement fixing effect of the prosthesis corresponding to the cartilage defect surface in the artificial hip joint and the knee joint can be improved, so that the method is very suitable for large-scale application and popularization in the field of joint replacement.

Description

Technical Field

[0001] The present invention belongs to the technical field of metal prosthesis manufacturing, and in particular relates to a preparation method, device and product of a metal prosthesis for articular surface cartilage defects. Background Art

[0002] The hip and knee joints are important weight-bearing joints in the lower limbs, and their structure and function are important components of the human movement system. Currently, for hip and knee cartilage lesions, such as osteoarthritis, rheumatoid arthritis and other diseases, joint replacement technology is usually used clinically to treat severely damaged articular cartilage structure and possible deformities, in order to relieve hip and knee pain, improve hip and knee function, correct hip and knee deformities and achieve long-term stability.

[0003] Among them, hip replacement includes conventional hip replacement and hip surface replacement; knee replacement includes: patellar joint surface replacement, unicompartmental replacement, total knee replacement and other different types. The main difference between the above-mentioned different types of replacement lies in the range of replacement, which depends on the range of cartilage destruction. Among them, the diseased cartilage and part of the subchondral bone can be removed with an oscillating saw through surgery, and then the metal prosthesis is fixed to the bone surface of the femoral condyle after osteotomy through bone cement technology or non-bone cement technology. In this way, an artificial joint structure with a metal-polyethylene interface is formed in the acetabulum and femoral head, the distal femoral articular surface and the proximal tibial articular surface, so that the function of joint replacement can be achieved.

[0004] The more commonly used fixation methods for the hip joint are cementless fixation or biological fixation (i.e., direct contact and growth between the bone and the implant surface to form bone integration), while the knee joint is fixed with bone cement. Among them, there is a certain loosening rate in the long term for bone cement fixation; therefore, cementless knee replacement is currently being tried; however, for the hip and knee joints, the main problems of cementless fixation are initial stability and long-term aseptic loosening, and currently, there is no metal prosthesis suitable for cementless fixation, resulting in poor stability of cementless fixation and a loosening rate of more than 30%; therefore, based on the aforementioned deficiencies, how to provide a metal prosthesis that can improve the cementless fixation effect in hip and knee replacement has become an urgent problem to be solved. Summary of the invention

[0005] The purpose of the present invention is to provide a method, device and product for preparing a metal prosthesis for articular surface cartilage defects, so as to solve the problem that there is no metal prosthesis suitable for non-cement fixation in the prior art, resulting in poor stability and high loosening rate of non-cement fixation.

[0006] In order to achieve the above object, the present invention adopts the following technical solutions:

[0007] In a first aspect, a method for preparing a metal prosthesis for a cartilage defect on a joint surface is provided, comprising:

[0008] Obtaining medical images of the patient's joints;

[0009] constructing a three-dimensional model of the patient's joint based on the medical image;

[0010] According to the three-dimensional model, a cartilage defect surface on the patient's joint is determined, and the prosthesis information is generated using the cartilage defect surface, wherein the prosthesis information includes a chimeric anchoring portion between a contact surface of a metal prosthesis and the patient's joint and structural parameters of the chimeric anchoring portion, and the chimeric anchoring portion is used to anchor the connection between the metal prosthesis and the patient's joint;

[0011] Generate a metal prosthesis model of the patient's joint using the three-dimensional model and the structural parameters of the embedded anchoring part in the prosthesis information, wherein the metal prosthesis model includes a prosthesis body and the embedded anchoring part;

[0012] The metal prosthesis model is introduced into a prosthesis manufacturing device based on 3D printing, so that the prosthesis manufacturing device performs 3D printing processing according to the metal prosthesis model to obtain a metal prosthesis corresponding to the patient's joint.

[0013] Based on the above disclosed content, the present invention first obtains a medical image of the patient's joint, and then constructs a three-dimensional model of the patient's joint based on the medical image. In this way, the cartilage defect surface on the patient's joint can be determined based on the three-dimensional model, that is, the joint replacement area can be determined; then, based on the joint replacement area, prosthesis information including the interlocking anchoring part between the metal prosthesis and the contact surface of the patient's joint and its structural parameters can be generated; then, the aforementioned three-dimensional model and the structural parameters of the aforementioned interlocking anchoring part can be used to generate a metal prosthesis model of the patient's joint; finally, the metal prosthesis model is imported into a prosthesis manufacturing device based on 3D printing, and a metal prosthesis corresponding to the patient's joint can be manufactured.

[0014] Through the above design, the present invention, on the basis of the traditional metal prosthesis, additionally adds an interlocking anchoring portion between the contact surface of the metal prosthesis and the patient's joint, so as to strengthen the connection between the metal prosthesis and the patient's joint through the interlocking anchoring portion; at the same time, the 3D printing technology is used to process the metal prosthesis with a highly complex configuration, so that the processing accuracy can be guaranteed, so that the processed interlocking anchoring portion can fit the joint better; thus, the present invention can improve the non-cement fixation effect of the prosthesis corresponding to the cartilage defect surface in the artificial hip joint and knee joint, and is therefore very suitable for large-scale application and promotion in the field of joint replacement.

[0015] In a possible design, the embedded anchoring portion adopts a protruding structure.

[0016] In a possible design, the contact surface between the metal prosthesis and the patient's joint is a porous structure, and the embedded anchoring portion is located on the porous structure.

[0017] In a possible design, the cartilage defect surface is used to generate prosthesis information, including:

[0018] Obtaining personnel information of a person corresponding to the patient's joint and the osteotomy thickness of the patient's joint;

[0019] Determining the area and surface thickness of the cartilage defect surface;

[0020] Determining structural parameters of the embedded anchoring portion according to the personnel information, the osteotomy thickness, the area of ​​the cartilage defect surface and the surface thickness, wherein the structural parameters include shape and size information of the embedded anchoring portion;

[0021] The prosthesis information is generated based on the structural parameters of the fitting anchor.

[0022] In one possible design, after generating the metal prosthesis model of the patient's joint, the method further includes:

[0023] Generate laser etching data based on the structural parameters of the embedded anchoring part in the three-dimensional model and the metal prosthesis model, wherein the laser etching data includes etching data on the target surface of the patient's joint corresponding to the embedded anchoring part, and the target surface is a contact surface on the patient's joint corresponding to the embedded anchoring part;

[0024] The laser etching data is output and displayed.

[0025] In a possible design, after obtaining the metal prosthesis corresponding to the patient's joint, the method further includes:

[0026] Generate prosthetic post-processing instructions;

[0027] The prosthesis post-processing instruction is sent to a prosthesis post-processing device, so that the prosthesis post-processing device performs post-processing on the metal prosthesis based on the prosthesis post-processing instruction, so as to complete the processing of the metal prosthesis after the post-processing, wherein the post-processing includes polishing.

[0028] In a possible design, the medical image includes: a CT image and an MR image;

[0029] Wherein, constructing a three-dimensional model of the patient's joint based on the medical image includes:

[0030] Based on the CT image and the MR image, a three-dimensional model of the patient's joint is constructed.

[0031] In a second aspect, a device for preparing a metal prosthesis for a cartilage defect on a joint surface is provided, comprising:

[0032] An acquisition unit, used for acquiring a medical image of a patient's joint;

[0033] A first modeling unit, configured to construct a three-dimensional model of a patient's joint based on the medical image;

[0034] a second modeling unit, for determining a cartilage defect surface on the patient's joint according to the three-dimensional model, and generating prosthesis information using the cartilage defect surface, wherein the prosthesis information includes a chimeric anchoring portion between a contact surface of a metal prosthesis and the patient's joint and structural parameters of the chimeric anchoring portion, and the chimeric anchoring portion is used to anchor the connection between the metal prosthesis and the patient's joint;

[0035] The second modeling unit is further used to generate a metal prosthesis model of the patient's joint by using the three-dimensional model and the structural parameters of the embedded anchoring part in the prosthesis information, wherein the metal prosthesis model includes a prosthesis body and the embedded anchoring part;

[0036] The data import unit is used to import the metal prosthesis model into a prosthesis manufacturing device based on 3D printing, so that the prosthesis manufacturing device performs 3D printing processing according to the metal prosthesis model to obtain a metal prosthesis corresponding to the patient's joint.

[0037] In the third aspect, another device for preparing a metal prosthesis for cartilage defects on the joint surface is provided. Taking the device as an electronic device as an example, the device includes a memory, a processor and a transceiver which are communicatively connected in sequence, wherein the memory is used to store computer programs, the transceiver is used to send and receive messages, and the processor is used to read the computer program to execute the method for preparing a metal prosthesis for cartilage defects on the joint surface as described in the first aspect or any possible design of the first aspect.

[0038] In a fourth aspect, a storage medium is provided, on which instructions are stored. When the instructions are run on a computer, a method for preparing a metal prosthesis for articular surface cartilage defects as described in the first aspect or any possible design of the first aspect is executed.

[0039] In a fifth aspect, a computer program product comprising instructions is provided, which, when executed on a computer, causes the computer to execute a method for preparing a metal prosthesis for articular surface cartilage defects as described in the first aspect or any possible design of the first aspect.

[0040] Beneficial effects:

[0041] (1) Based on the traditional metal prosthesis, the present invention adds an additional interlocking anchoring part between the contact surface of the metal prosthesis and the patient's joint, so as to strengthen the connection between the metal prosthesis and the patient's joint through the interlocking anchoring part; at the same time, 3D printing technology is used to process the metal prosthesis with a highly complex configuration, so that the processing accuracy can be guaranteed, so that the processed interlocking anchoring part can fit the joint better; therefore, the present invention can improve the non-cement fixation effect of the prosthesis corresponding to the cartilage defect surface in the artificial hip joint and knee joint, and is very suitable for large-scale application and promotion in the field of joint replacement.

[0042] (2) The present invention constructs a three-dimensional model of the patient's joint through CT images and MR images, and based on this, determines the cartilage defect surface; in this way, the part of the cartilage that is severely worn can be accurately obtained, and the replacement area can be determined, thereby minimizing the amount of osteotomy; based on this, a highly customized function of the metal prosthesis is achieved, thereby improving the flexibility of use.

[0043] (3) The present invention can also generate etching data of the contact surface corresponding to the interlocking anchoring part on the patient's joint based on the structural parameters of the interlocking anchoring part in the three-dimensional model and the metal prosthesis model, and output it for display; in this way, it can provide accurate control data for the laser osteotomy robot, thereby ensuring the accurate interlocking of the interlocking anchoring part on the metal prosthesis with the joint. BRIEF DESCRIPTION OF THE DRAWINGS

[0044] Figure 1 A schematic flow chart of the steps of a method for preparing a metal prosthesis for articular surface cartilage defects provided by an embodiment of the present invention;

[0045] Figure 2 A schematic diagram of the structure of a device for preparing a metal prosthesis for articular surface cartilage defects provided by an embodiment of the present invention;

[0046] Figure 3 A schematic diagram of the structure of an electronic device provided by an embodiment of the present invention. DETAILED DESCRIPTION

[0047] In order to more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the present invention will be briefly introduced below in combination with the drawings and the description of the embodiments or the prior art. Obviously, the following description of the structure of the drawings is only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work. It should be noted that the description of these embodiments is used to help understand the present invention, but does not constitute a limitation of the present invention.

[0048] It should be understood that although the terms first, second, etc. may be used herein to describe various units, these units should not be limited by these terms. These terms are only used to distinguish one unit from another unit. For example, a first unit can be referred to as a second unit, and similarly, a second unit can be referred to as a first unit without departing from the scope of the exemplary embodiments of the present invention.

[0049] It should be understood that the term "and / or" that may appear in this article is merely a description of the association relationship between associated objects, indicating that three relationships may exist. For example, A and / or B can represent three situations: A exists alone, B exists alone, and A and B exist at the same time. The term " / and" that may appear in this article describes another type of association object relationship, indicating that two relationships may exist. For example, A / and B can represent two situations: A exists alone, and A and B exist alone. In addition, the character " / " that may appear in this article generally indicates that the previous and next associated objects are in an "or" relationship.

[0050] Example:

[0051] See also Figure 1 As shown, the preparation method of the metal prosthesis for articular surface cartilage defect provided by the present embodiment first obtains a medical image of the patient's joint, and then constructs a three-dimensional model of the patient's joint based on the medical image, so that the joint replacement area on the patient's joint can be determined based on the three-dimensional model; then, the interlocking anchoring part between the metal prosthesis and the contact surface of the patient's joint and its structural parameters can be generated based on the joint replacement area; then, the metal prosthesis model of the patient's joint can be generated using the aforementioned three-dimensional model and the structural parameters of the aforementioned interlocking anchoring part; finally, the metal prosthesis model is introduced into a prosthesis manufacturing device based on 3D printing, and a metal prosthesis corresponding to the patient's joint can be manufactured; thereby In the present method, an interlocking anchoring portion is designed between the contact surface of the metal prosthesis and the patient's joint, so as to strengthen the connection between the metal prosthesis and the patient's joint through the interlocking anchoring portion; at the same time, 3D printing technology is used to process the metal prosthesis with a highly complex configuration, based on which the processing accuracy can be guaranteed, so that the interlocking anchoring portion obtained by processing can fit the joint more closely; thus, the present method can improve the non-cement fixation effect of the prosthesis corresponding to the cartilage defect surface in the artificial hip joint and the knee joint, so that it is very suitable for large-scale application and promotion in the field of joint replacement; among them, for example, the present method can be but not limited to running on the prosthesis design end side, and optionally, the prosthesis design end can be but not limited to a personal computer (PC). It can be understood that the aforementioned execution subject does not constitute a limitation on the embodiments of the present application, and accordingly, the operation steps of the present method can be but not limited to the following steps S1 to S5.

[0052] S1. Obtain a medical image of the patient's joint; in a specific implementation, examples of medical images may include but are not limited to: CT images and MR images, wherein CT images can provide high-resolution bone images, showing the details of the bones very clearly, and are suitable for bone structure analysis; and MR images can provide images with high soft tissue contrast, which are very useful for displaying bone marrow and soft tissue; based on this, this embodiment constructs a three-dimensional model of the patient's joint based on the aforementioned CT images and MR images, so that the joint replacement area can be determined based on the three-dimensional model and a corresponding metal prosthesis model can be generated; wherein, the generation process of the three-dimensional model of the patient's joint may be but is not limited to as shown in the following step S2.

[0053] S2. Based on the medical image, a three-dimensional model of the patient's joint is constructed; in a specific application, the following discloses one method of constructing a three-dimensional model of the patient's joint based on the aforementioned CT image and MR image, as shown below:

[0054] The first step: import the CT image and the MR image into the image processing software to perform image calibration and image segmentation to obtain a segmented image; wherein, the aforementioned image processing software may include but is not limited to Mimics, 3-matic, ImageJ, ITK-SNAP and other software, and image calibration is to adjust the image resolution and contrast; finally, image segmentation is to separate the bones from the background and other tissues (such as muscle and fat); optionally, the image segmentation may be completed by threshold segmentation, region growing, edge detection and other methods, and the bones include bony structures (i.e., hard tissues constituting bones) and cartilage structures (i.e., structures composed of cartilage tissues in bones).

[0055] After obtaining the segmented image (i.e., obtaining the image containing the bone region), bone extraction can be performed, and the process is shown in the second step below.

[0056] Step 2: extract the bone region from the segmented image to obtain an initial bone image, and perform morphological processing on the initial bone image to obtain a bone image; in this embodiment, for example, but not limited to, threshold segmentation technology can be used to extract the bone region, and the morphological processing can include but is not limited to expansion, corrosion, opening and closing operations, so that the noise and small holes in the initial bone image can be removed to obtain an accurate bone image.

[0057] After the bone region is extracted, three-dimensional reconstruction can be performed, and the process is shown in the third step below.

[0058] The third step: perform voxel modeling on the bone image to stack the two-dimensional bone image into a three-dimensional voxel model, and perform surface reconstruction on the voxel model to extract the surface model of the bone from the voxel model to obtain an initial three-dimensional model; in the specific implementation, for example, but not limited to, the marching cubes algorithm can be used for surface reconstruction; of course, other surface reconstruction algorithms can also be used, and are not limited to the aforementioned examples.

[0059] After obtaining the initial three-dimensional model, model post-processing may be performed to obtain a three-dimensional model of the patient's joint after model post-processing, wherein the model post-processing process may be, but is not limited to, as shown in the fourth step below.

[0060] Step 4: Post-process the initial three-dimensional model to obtain the three-dimensional model after post-processing; in specific implementation, the post-processing of the example model may include but is not limited to model smoothing (the function is to reduce noise and irregular parts on the model surface), refinement (adjusting the geometric details of the model) and correction (removing artifacts on the model).

[0061] In this way, after the first to fourth steps mentioned above, a three-dimensional model containing the bone structure and cartilage structure of the diseased joint can be obtained; then, the replacement area can be determined based on the three-dimensional model, so as to construct a metal prosthesis according to the replacement area; wherein, the process of determining the replacement area can be but is not limited to as shown in the following step S3.

[0062] S3. Based on the three-dimensional model, the cartilage defect surface on the patient's joint is determined, and the prosthesis information is generated using the cartilage defect surface, wherein the prosthesis information includes an interlocking anchoring portion between the contact surface of the metal prosthesis and the patient's joint and structural parameters of the interlocking anchoring portion, and the interlocking anchoring portion is used to anchor the connection between the metal prosthesis and the patient's joint.

[0063] In this embodiment, for example, but not limited to, the aforementioned three-dimensional model can be visualized for display, so that medical staff can determine the area and surface thickness of the cartilage defect surface in the patient's joint based on the three-dimensional model, as well as the aforementioned CT image and MR image, and then upload it to the prosthesis design end; in this way, the prosthesis design end can determine the cartilage defect surface and the corresponding parameters (i.e., the area and surface thickness of the cartilage defect surface) in response to the human-computer interaction operation.

[0064] After the cartilage defect surface is determined, the prosthesis information can be generated based on it, that is, the shape of the interlocking anchoring part between the metal prosthesis and the contact surface of the patient's joint and the corresponding size parameters (i.e. the aforementioned structural parameters) can be determined; among which, for example, but not limited to, the following steps S31 to S34 can be used to obtain the structural parameters of the aforementioned interlocking anchoring body.

[0065] S31. Obtain the personnel information of the person corresponding to the patient's joint, and the osteotomy thickness of the patient's joint; in the specific implementation, the personnel information can be, but is not limited to, the weight of the person, and the osteotomy thickness can be obtained by medical staff based on CT images and MR images, and pre-stored in the prosthesis design end, so that the data can be retrieved when used.

[0066] After obtaining the weight of the person and the osteotomy thickness of the patient's joint, the structural parameters of the chimeric anchoring portion can be determined in combination with the aforementioned cartilage defect surface, and the process is shown in the following steps S32 and S33.

[0067] S32. Determine the area and surface thickness of the cartilage defect surface; in this embodiment, the process of obtaining the area and surface thickness of the cartilage defect surface has been explained above and will not be repeated here; in this way, after obtaining the area and surface thickness of the cartilage defect surface, combined with the person's weight and osteotomy thickness, the shape and size information of the embedded anchoring part can be determined, and the process can be but not limited to as shown in the following step S33.

[0068] S33. According to the personnel information, the osteotomy thickness, the area of ​​the cartilage defect surface and the surface thickness, the structural parameters of the interlocking anchoring part are determined, wherein the structural parameters include the shape and size information of the interlocking anchoring part; in specific applications, for example, a parameter database of the anchoring part is stored in the prosthesis design end, wherein the parameter database stores different structural parameters, and any structural parameter corresponds to a calibrated personnel weight, a calibrated osteotomy thickness, a calibrated area and a calibrated surface thickness, etc. Therefore, when in use, it is directly matched in the parameter database according to the aforementioned data.

[0069] Optionally, the chimeric anchoring portion mentioned in the example may be but is not limited to a protruding structure. Specifically, its shape may be cylindrical, hexagonal, pentagonal, etc. For example, the femoral head may be mainly a columnar structure. The tibial side, femoral side, and anterior and posterior condyle feature chimeric structures should take into account operability during implantation, and are generally in the form of curves (i.e., an anchoring portion with a curved outline formed by multiple protrusions); at the same time, its size information mainly includes the diameter and depth of the protrusions, etc. The chimeric anchoring portion is intended to achieve a stable fit between the metal prosthesis and the joint contact surface.

[0070] After obtaining the shape and size information of the embedded anchoring portion, the aforementioned prosthesis information can be generated based on this, and the process is shown in the following step S34.

[0071] S34. Generate the prosthesis information based on the structural parameters of the embedded anchoring part.

[0072] In this way, through the aforementioned steps S31 to S34, the structural parameters of the interlocking anchoring part between the contact surface of the metal prosthesis and the patient's joint can be determined through the cartilage defect surface; then, the aforementioned three-dimensional model can be combined to establish a metal prosthesis model, wherein the construction process of the metal prosthesis model can be but is not limited to as shown in the following step S4.

[0073] S4. Generate a metal prosthesis model of the patient's joint using the structural parameters of the interlocking anchoring part in the three-dimensional model and the prosthesis information, wherein the metal prosthesis model includes a prosthesis body and the interlocking anchoring part. In this embodiment, the metal prosthesis model can be constructed by, but is not limited to, CAD software. Specifically, the structural parameters of the aforementioned three-dimensional model and the interlocking anchoring part are imported into the CAD software. Then, in response to human-computer interaction instructions, the metal prosthesis model is constructed based on the aforementioned three-dimensional model and structural parameters.

[0074] Furthermore, for example, the contact surface between the metal prosthesis and the patient's joint is a porous structure, and the interlocking anchoring portion is located on the porous structure; in this way, by designing the aforementioned contact surface as a porous structure, bone tissue can be allowed to grow into the pores, thereby increasing the fixation of the prosthesis.

[0075] After the metal prosthesis model is constructed, it can be imported into a prosthesis manufacturing device to complete the manufacturing of the metal prosthesis, wherein the model importing process can be but is not limited to the following step S5.

[0076] S5. Import the metal prosthesis model into a prosthesis manufacturing device based on 3D printing, so that the prosthesis manufacturing device performs 3D printing processing according to the metal prosthesis model to obtain a metal prosthesis corresponding to the diseased joint; in the specific implementation, since the main body of the metal prosthesis and its interlocking anchoring part have a relatively complex configuration, this embodiment uses 3D printing technology (of course, high-precision CNC machine tools can also be used for processing) to carry out processing and manufacturing, so that the processing accuracy can be guaranteed, so that the processed prosthesis main body and interlocking anchoring part can better fit the joint; at the same time, after obtaining the metal prosthesis, a prosthesis post-processing instruction can also be generated, and then the prosthesis post-processing instruction is sent to the prosthesis post-processing device, so that the prosthesis post-processing device performs post-processing on the metal prosthesis based on the prosthesis post-processing instruction, so as to complete the processing of the metal prosthesis after post-processing.

[0077] Optionally, the post-processing mentioned above may include, but is not limited to, polishing, so that pits and defects on the surface of the metal body can be removed, thereby achieving the purpose of improving the surface flatness.

[0078] In addition, in this embodiment, laser etching data can also be generated based on the structural parameters of the interlocking anchoring part in the three-dimensional model and the metal prosthesis model, and the laser etching data can be output and displayed (of course, it can also be sent to the laser osteotomy robot); wherein the laser etching data includes etching data on the target surface of the patient's joint corresponding to the interlocking anchoring part, and the target surface is the contact surface on the patient's joint corresponding to the interlocking anchoring part; in this way, precise control data (i.e., clear cartilage etching and concave side etching data of the anchoring part) can be provided to the laser osteotomy robot during the subsequent installation process, thereby ensuring the precise interlocking of the interlocking anchoring part on the metal prosthesis with the joint.

[0079] Based on this, the preparation process of the aforementioned metal prosthesis can be summarized as follows:

[0080] (1) Multimodal reconstruction is performed based on data such as X-rays, CT images, and MRI images to obtain a three-dimensional model containing bony and cartilage structures.

[0081] (2) Confirm the replacement area based on the three-dimensional model and clarify the replacement range, that is, determine the cartilage defect surface so that the interlocking anchoring part between the contact surface of the metal prosthesis and the patient's joint and the structural parameters of the interlocking anchoring part can be obtained based on the cartilage defect surface.

[0082] (3) Based on the aforementioned three-dimensional model and the structural parameters of the interlocking anchoring part, the prosthesis is designed through CAD design software to obtain a metal prosthesis model, and then the metal prosthesis model and STL file are output; wherein, the design elements of the metal prosthesis model mainly include the area of ​​the replacement region, the surface thickness, the weight of the patient, the osteotomy thickness, and the tibial side polyethylene pad fixing structure and other information, and the most characteristic feature is the convex design on the prosthesis bone contact side, that is, a convex interlocking anchoring part is set between the contact surface of the metal prosthesis and the patient's joint.

[0083] (4) The file is imported into a titanium alloy 3D printing system (i.e., prosthesis manufacturing equipment) such as an electron beam or laser for prosthesis processing and printing, and then post-processing such as polishing is performed.

[0084] At this point, the manufacture of the metal prosthesis can be completed.

[0085] Then, the metal prosthesis can be installed, and the process is as follows:

[0086] (5) Based on the three-dimensional model and the structural parameters of the interlocking anchoring part in the metal prosthesis model, the laser etching data of the contact surface on the patient's joint corresponding to the interlocking anchoring part is generated, and the data is imported into the positioning planning system of the laser osteotomy robot; wherein, this step is equivalent to importing the prosthesis design data into the graphic workstation of the laser osteotomy robot to clarify the cartilage etching and the concave side etching of the fixed structure, that is, the parameters are clarified for the control of the osteotomy robot.

[0087] (6) After the replacement area is exposed, the position of the robot system is registered, and the laser osteotomy robot is controlled to process the bone bed in the defect area.

[0088] (7) Controlling the laser osteotomy robot to run according to the aforementioned laser etching data; in this way, it is equivalent to performing cartilage etching and etching of the cancellous bone contact side of the metal interlocking fixation structure according to the aforementioned laser etching data (i.e. etching away the bone structure to ensure that the depth of the depression is consistent with the height of the protrusion), so that the joint contact surface can be completely matched with the protrusion of the prosthesis, thereby achieving an interlocking effect; based on this, the laser can be used to accurately cut and engrave the bone to ensure that the prosthesis can be firmly fixed in the correct position; thereby, the installation of the metal prosthesis can be completed.

[0089] Thus, through the preparation method of the metal prosthesis for articular surface cartilage defects described in detail in the aforementioned steps S1 to S5, the principles of laser etching and interlocking fixation are used to add an interlocking anchoring portion between the contact surface of the metal prosthesis and the patient's joint, so as to strengthen the connection between the metal prosthesis and the patient's joint through the interlocking anchoring portion; at the same time, 3D printing technology is used to process the metal prosthesis with a highly complex configuration, so that the processing accuracy can be guaranteed, so that the processed interlocking anchoring portion can fit the joint better; thus, the present invention can improve the non-cement fixation effect of the prosthesis corresponding to the cartilage defect surface in the artificial hip joint and knee joint, and is therefore very suitable for large-scale application and promotion in the field of joint replacement.

[0090] like Figure 2 As shown, the second aspect of this embodiment provides a hardware device for implementing the method for preparing a metal prosthesis for articular surface cartilage defects described in the first aspect of the embodiment, comprising:

[0091] The acquisition unit is used to acquire medical images of the patient's joints.

[0092] The first modeling unit is used to construct a three-dimensional model of the patient's joint based on the medical image.

[0093] The second modeling unit is used to determine the cartilage defect surface on the patient's joint based on the three-dimensional model, and generate prosthesis information using the cartilage defect surface, wherein the prosthesis information includes an interlocking anchoring portion between the contact surface of the metal prosthesis and the patient's joint and structural parameters of the interlocking anchoring portion, and the interlocking anchoring portion is used to anchor the connection between the metal prosthesis and the patient's joint.

[0094] The second modeling unit is further used to generate a metal prosthesis model of the patient's joint using the three-dimensional model and the structural parameters of the interlocking anchoring part in the prosthesis information, wherein the metal prosthesis model includes a prosthesis body and the interlocking anchoring part.

[0095] The data import unit is used to import the metal prosthesis model into a prosthesis manufacturing device based on 3D printing, so that the prosthesis manufacturing device performs 3D printing processing according to the metal prosthesis model to obtain a metal prosthesis corresponding to the patient's joint.

[0096] The working process, working details and technical effects of the device provided in this embodiment can be found in the first aspect of the embodiment and will not be described in detail here.

[0097] like Figure 3 As shown, the third aspect of this embodiment provides another device for preparing a metal prosthesis for a cartilage defect on a joint surface. Taking the device as an electronic device as an example, the device includes: a memory, a processor and a transceiver that are communicatively connected in sequence, wherein the memory is used to store a computer program, the transceiver is used to send and receive messages, and the processor is used to read the computer program to execute the method for preparing a metal prosthesis for a cartilage defect on a joint surface as described in the first aspect of the embodiment.

[0098] For example, the memory may include, but is not limited to, random access memory (RAM), read-only memory (ROM), flash memory, first-in-first-out memory (FIFO) and / or first-in-last-out memory (FILO), etc. Specifically, the processor may include one or more processing cores, such as a 4-core processor, an 8-core processor, etc. The processor may be implemented in at least one hardware form of DSP (Digital Signal Processing), FPGA (Field-Programmable Gate Array), and PLA (Programmable Logic Array). At the same time, the processor may also include a main processor and a coprocessor. The main processor is a processor for processing data in the awake state, also known as a CPU (Central Processing Unit); the coprocessor is a low-power processor for processing data in the standby state.

[0099] In some embodiments, the processor may be integrated with a GPU (Graphics Processing Unit), which is responsible for rendering and drawing the content to be displayed on the display screen. For example, the processor may not be limited to a microprocessor of the STM32F105 series, a reduced instruction set computer (RISC) microprocessor, an X86 or other architecture processor, or a processor with an integrated embedded neural network processor (NPU); the transceiver may be, but is not limited to, a wireless fidelity (WIFI) wireless transceiver, a Bluetooth wireless transceiver, a general packet radio service technology (Genera l Packet Rad ioService, GPRS) wireless transceiver, a ZigBee protocol (a low-power LAN protocol based on the IEEE 802.15.4 standard, ZigBee) wireless transceiver, a 3G transceiver, a 4G transceiver and / or a 5G transceiver, etc. In addition, the device may also include, but is not limited to, a power module, a display screen and other necessary components.

[0100] The working process, working details and technical effects of the electronic device provided in this embodiment can be found in the first aspect of the embodiment and will not be described in detail here.

[0101] The fourth aspect of this embodiment provides a storage medium storing instructions for the method for preparing a metal prosthesis for a joint surface cartilage defect as described in the first aspect of the embodiment, that is, the storage medium stores instructions, and when the instructions are run on a computer, the method for preparing a metal prosthesis for a joint surface cartilage defect as described in the first aspect of the embodiment is executed.

[0102] The storage medium refers to a carrier for storing data, which may include but is not limited to a floppy disk, a CD, a hard disk, a flash memory, a USB flash drive and / or a memory stick, etc. The computer may be a general-purpose computer, a special-purpose computer, a computer network, or other programmable devices.

[0103] The working process, working details and technical effects of the storage medium provided in this embodiment can be found in the first aspect of the embodiment and will not be described in detail here.

[0104] The fifth aspect of this embodiment provides a computer program product comprising instructions, which, when executed on a computer, causes the computer to execute the method for preparing a metal prosthesis for articular surface cartilage defects as described in the first aspect of the embodiment, wherein the computer may be a general-purpose computer, a special-purpose computer, a computer network, or other programmable devices.

[0105] Finally, it should be noted that the above description is only a preferred embodiment of the present invention and is not intended to limit the protection scope of the present invention. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included in the protection scope of the present invention.

Claims

1. A method for preparing a metal prosthesis for articular surface cartilage defect, characterized in that: include: Obtaining medical images of the patient's joints; constructing a three-dimensional model of the patient's joint based on the medical image; According to the three-dimensional model, a cartilage defect surface on the patient's joint is determined, and the prosthesis information is generated using the cartilage defect surface, wherein the prosthesis information includes a chimeric anchoring portion between a contact surface of a metal prosthesis and the patient's joint and structural parameters of the chimeric anchoring portion, and the chimeric anchoring portion is used to anchor the connection between the metal prosthesis and the patient's joint; Generate a metal prosthesis model of the patient's joint using the three-dimensional model and the structural parameters of the embedded anchoring part in the prosthesis information, wherein the metal prosthesis model includes a prosthesis body and the embedded anchoring part; The metal prosthesis model is introduced into a prosthesis manufacturing device based on 3D printing, so that the prosthesis manufacturing device performs 3D printing processing according to the metal prosthesis model to obtain a metal prosthesis corresponding to the patient's joint.

2. The method according to claim 1, characterized in that The embedded anchoring portion adopts a convex structure.

3. The method according to claim 2, characterized in that The contact surface between the metal prosthesis and the patient's joint is a porous structure, and the embedded anchoring part is located on the porous structure.

4. The method according to claim 1, characterized in that: Using the cartilage defect surface, prosthesis information is generated, including: Obtaining personnel information of a person corresponding to the patient's joint and the osteotomy thickness of the patient's joint; Determining the area and surface thickness of the cartilage defect surface; Determining structural parameters of the embedded anchoring portion according to the personnel information, the osteotomy thickness, the area of ​​the cartilage defect surface and the surface thickness, wherein the structural parameters include shape and size information of the embedded anchoring portion; The prosthesis information is generated based on the structural parameters of the fitting anchor.

5. The method according to claim 1, characterized in that After generating the metal prosthesis model of the patient's joint, the method further comprises: Generate laser etching data based on the structural parameters of the embedded anchoring part in the three-dimensional model and the metal prosthesis model, wherein the laser etching data includes etching data on the target surface of the patient's joint corresponding to the embedded anchoring part, and the target surface is a contact surface on the patient's joint corresponding to the embedded anchoring part; The laser etching data is output and displayed.

6. The method according to claim 1, characterized in that After obtaining the metal prosthesis corresponding to the patient's joint, the method further includes: Generate prosthetic post-processing instructions; The prosthesis post-processing instruction is sent to a prosthesis post-processing device, so that the prosthesis post-processing device performs post-processing on the metal prosthesis based on the prosthesis post-processing instruction, so as to complete the processing of the metal prosthesis after the post-processing, wherein the post-processing includes polishing.

7. The method according to claim 1, characterized in that The medical images include: CT images and MR images; Wherein, constructing a three-dimensional model of the patient's joint based on the medical image includes: Based on the CT image and the MR image, a three-dimensional model of the patient's joint is constructed.

8. A device for preparing a metal prosthesis for articular surface cartilage defect, characterized in that: include: An acquisition unit, used for acquiring a medical image of a patient's joint; A first modeling unit, configured to construct a three-dimensional model of a patient's joint based on the medical image; a second modeling unit, for determining a cartilage defect surface on the patient's joint according to the three-dimensional model, and generating prosthesis information using the cartilage defect surface, wherein the prosthesis information includes a chimeric anchoring portion between a contact surface of a metal prosthesis and the patient's joint and structural parameters of the chimeric anchoring portion, and the chimeric anchoring portion is used to anchor the connection between the metal prosthesis and the patient's joint; The second modeling unit is further used to generate a metal prosthesis model of the patient's joint by using the three-dimensional model and the structural parameters of the embedded anchoring part in the prosthesis information, wherein the metal prosthesis model includes a prosthesis body and the embedded anchoring part; The data import unit is used to import the metal prosthesis model into a prosthesis manufacturing device based on 3D printing, so that the prosthesis manufacturing device performs 3D printing processing according to the metal prosthesis model to obtain a metal prosthesis corresponding to the patient's joint.

9. A device for preparing a metal prosthesis for articular surface cartilage defect, characterized in that: include: A memory, a processor and a transceiver which are sequentially connected in communication, wherein the memory is used to store a computer program, the transceiver is used to send and receive messages, and the processor is used to read the computer program to execute the method for preparing a metal prosthesis for articular surface cartilage defects as described in any one of claims 1 to 7.

10. A computer program product comprising instructions, characterized in that When the instructions are executed on a computer, the computer is caused to execute the method for preparing a metal prosthesis for articular surface cartilage defects as claimed in any one of claims 1 to 7.

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