Mixing device for metformin production

Abstract

The invention relates to the field of metformin tablet production, in particular to a mixing device for metformin production. The device comprises a mixing box, a crushing box is fixed to one end of the mixing box, a feeding port is formed in the top end of the crushing box, a filter plate is slidably connected into the crushing box, a plurality of transmission rollers are rotatably connected into the mixing box, stirring blades are fixed to the top ends and the bottom ends of the outer sides of the transmission rollers, and a discharging port is fixed to the other end of the bottom end of the outer side of the mixing box; a closing plate is slidably connected to the inner side of the discharging opening. According to the mixing device for metformin production, raw materials, needing to be produced, of metformin are placed and poured into the feeding opening, then the filter plate slides to evenly scatter the raw materials of metformin production, and therefore the mixing effect of the raw materials of metformin is promoted; and then the transmission roller and the stirring blades are rotated to deeply mix the metformin raw material.

Description

Technical Field

[0001] The invention relates to the field of metformin tablet production, and in particular to a mixing device for metformin production. Background Art

[0002] In the pharmaceutical industry, mixing devices are one of the indispensable equipment on the production line. Their main function is to evenly mix the raw materials of different ingredients to ensure the quality and stability of the final product. The design and selection of mixing devices are crucial to improving production efficiency, reducing costs and ensuring product quality; Metformin hydrochloride tablets are used for patients with type 2 diabetes who are not satisfied with diet control alone, especially those who are obese and have hyperinsulinemia. This drug not only has the effect of lowering blood sugar, but also may have the effect of reducing weight and hyperinsulinemia. It can be effective for patients with poor efficacy of certain sulfonylureas. For example, when used in combination with sulfonylureas, intestinal glycosidase inhibitors or thiazolidinediones hypoglycemic drugs, the effect is better than using them alone. It can also be used for patients treated with insulin to reduce the amount of insulin.

[0003] When using the above technology, it was found that the following technical problems exist in the prior art: the existing mixing device for the production of metformin hydrochloride tablets has a complicated structure, is inconvenient to use, has low mixing quality, uneven mixing, and high manufacturing cost. Many small pharmaceutical factories have small production scales and it is difficult to purchase and use large mixing devices. The versatility is low and it is also very inconvenient when discharging materials. Some mixed materials are not easy to be discharged quickly and cleanly from the inside of the device, resulting in certain waste. For this reason, we designed a mixing device for metformin production to provide another technical solution to the above technical problems. Summary of the invention

[0004] Based on this, it is necessary to provide a mixing device for metformin production in response to the above technical problems. First, the staff turns on the power of the device, and then places the raw materials to be produced by metformin into the inside of the feed port, and then slides the filter plate to evenly disperse the raw materials for metformin production, thereby promoting the mixing effect of the metformin raw materials, and then rotates the transmission roller and the stirring blade to deeply mix the metformin raw materials, and finally pulls the closing plate to separate from the discharge port, so that the mixed metformin raw materials are discharged from the discharge port; In order to solve the above technical problems, the present invention adopts the following technical solutions: A mixing device for metformin production comprises a mixing box, one end of which is fixed with a crushing box, a top end of which is provided with a feed port, a filter plate is slidably connected to the inside of the crushing box, a plurality of transmission rollers are rotatably connected to the inside of the mixing box, stirring blades are fixed to the top and bottom ends of the outer sides of the transmission rollers, and a discharge port is fixed to the other end of the outer bottom end of the mixing box.

[0005] As a preferred embodiment of the mixing device for metformin production provided by the present invention, a reciprocating drive mechanism for driving the filter plate to vibrate is arranged inside the crushing box, and the reciprocating drive mechanism includes servo motor 2, a transmission rod, a drive rod, a linkage rod and a drive rod. Guide grooves are provided at both ends of the crushing box, and the inner side of the guide groove is slidably connected to the filter plate.

[0006] As a preferred embodiment of the mixing device for metformin production provided by the present invention, the interior of the crushing box is rotatably connected to a transmission rod, both ends of the outer side of the transmission rod are rotatably connected to drive rods, the end of the drive rod away from the transmission rod is rotatably connected to a linkage rod, and the end of the linkage rod away from the drive rod is rotatably connected to the filter plate.

[0007] As a preferred embodiment of the mixing device for producing metformin provided by the present invention, a servo motor 2 is fixed to one end of the crushing box, and an output end of the servo motor 2 passes through the crushing box and is fixed to a transmission rod.

[0008] As a preferred embodiment of the mixing device for producing metformin provided by the present invention, a material guide block is fixed at the bottom end of the crushing box.

[0009] As a preferred embodiment of the mixing device for metformin production provided by the present invention, a driving mechanism for driving a transmission roller and a stirring blade to move is arranged inside the mixing box, and the driving mechanism includes an internal gear, a planetary gear and a transmission wheel. An internal gear is fixed to the top of the mixing box, and a transmission wheel is rotatably connected to the top of the mixing box. The outer side of the transmission wheel is meshedly connected to a plurality of planetary gears, and the outer side of the planetary gear is meshedly connected to the internal gear.

[0010] As a preferred embodiment of the mixing device for metformin production provided by the present invention, an annular guide rail is provided at the top end of the mixing box, and the top end of the planetary gear is slidably connected to the annular guide rail.

[0011] As a preferred embodiment of the mixing device for metformin production provided by the present invention, a servo motor is fixed to the top of the mixing box, a worm is fixed to the output end of the servo motor, a worm is rotatably connected to the top of the mixing box, the bottom end of the worm wheel is fixed to the transmission wheel, and the outer side of the worm is meshingly connected to the worm wheel.

[0012] As a preferred embodiment of the mixing device for metformin production provided by the present invention, a lifting mechanism for tilting the mixing box is provided at the bottom end of the crushing box, and the lifting mechanism includes a base, a hydraulic rod and a linkage rod. One end of the bottom end of the base is rotatably connected to the hydraulic rod, and the output end of the hydraulic rod is rotatably connected to the crushing box. A linkage rod is fixed to the other end of the base, and the inner side of the linkage rod is rotatably connected to the mixing box.

[0013] As a preferred embodiment of the mixing device for metformin production provided by the present invention, a closing plate is slidably connected to the inner side of the discharge port, and supporting feet are fixed on both sides of the bottom end of the mixing box.

[0014] It can be seen without a doubt that the above-mentioned technical solution of the present application can definitely solve the technical problem to be solved by the present application.

[0015] At the same time, through the above technical solutions, the present invention has at least the following beneficial effects: The present invention provides a mixing device for metformin production. The raw materials to be produced by metformin are placed into the inside of the feed port, and the servo motor 2 is started to drive the transmission rod to rotate, and the transmission rod drives the driving rod and the linkage rod to reciprocate, so that the linkage rod drives the filter plate to reset and vibrate up and down along the guide on the inner side of the guide groove, so as to evenly disperse the accumulated metformin raw materials, thereby promoting the device to mix the metformin raw materials; By starting the servo motor, the worm and the worm wheel are driven to rotate, and the worm wheel drives the transmission wheel to rotate, and the transmission wheel drives the three planetary gears to move, so that the three planetary gears rotate and rotate along the inner side of the internal gear, so that the planetary gears drive the transmission roller and the stirring blade to mix the metformin raw materials inside the mixing box, and the three planetary gears rotate as a whole, thereby greatly increasing the mixing effect of the transmission roller and the stirring blade on the metformin raw materials; The closed plate is pulled apart from the discharge port to discharge the mixed metformin raw material, thereby starting the hydraulic rod to drive the crushing box, the mixing box and the linkage rod to rotate, so that the mixing box and the discharge port are tilted, so as to improve the cleanliness of the discharge of the mixed metformin raw material on the mixing box side. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the accompanying drawings required for use in the description of the embodiments will be briefly introduced below. Obviously, the accompanying drawings described below are some embodiments of the present invention. For ordinary technicians in this field, other accompanying drawings can be obtained based on these accompanying drawings without paying any creative work.

[0017] Figure 1It is a schematic diagram of the overall structure of the present invention; Figure 2 This is a schematic diagram of the structure of the mixing box and the crushing box in an inclined state of the present invention; Figure 3 It is a schematic diagram of the internal structure of the crushing box and the mixing box of the present invention; Figure 4 This is a schematic diagram of the sliding connection structure between the crushing box and the filter plate of the present invention; Figure 5 It is a schematic diagram of the structure of the reciprocating drive mechanism of the present invention; Figure 6 This is a schematic diagram of the meshing connection structure of the servo motor 1 and the worm gear of the present invention; Figure 7 It is a schematic diagram of the structure between the transmission roller and the stirring blade of the present invention; Figure 8 It is a schematic diagram of the structure between the internal gear, the planetary gear and the transmission wheel of the present invention; Fig. 9 This is a schematic diagram of the internal structure of the present invention in which the discharge port and the closing plate are slidably connected; Fig.10 It is a schematic diagram of the structure between the base, hydraulic rod and crushing box of the present invention.

[0018] In the figure: 1. base; 2. mixing box; 3. crushing box; 4. servo motor 1; 5. feed port; 6. support foot; 7. servo motor 2; 8. worm gear; 9. guide groove; 10. hydraulic rod; 11. discharge port; 12. transmission roller; 13. stirring blade; 14. internal gear; 15. planetary gear; 16. transmission wheel; 17. linkage rod; 18. transmission rod; 19. driving rod; 20. guide block; 21. filter plate; 22. closing plate. DETAILED DESCRIPTION

[0019] In order to make the purpose, technical solution and advantages of the present invention more clearly understood, the present invention is further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not intended to limit the present invention.

[0020] As mentioned in the background art, the existing mixing device for producing metformin hydrochloride tablets has a complicated structure, is inconvenient to use, has low mixing quality, and causes uneven mixing. At the same time, the manufacturing cost is high. Many small pharmaceutical factories have small production scales and find it difficult to purchase and use large mixing devices. The mixing device has low versatility and is also very inconvenient when discharging materials. Some of the mixed materials cannot be discharged quickly and cleanly from the inside of the device, resulting in certain waste.

[0021] In order to solve this technical problem, the present invention provides a mixing device for producing metformin.

[0022] Specifically, please refer to Figure 1-Figure 10, a mixing device for producing metformin specifically comprises: It includes a mixing box 2, one end of which is fixed with a crushing box 3, a feeding port 5 is provided at the top of the crushing box 3, a filter plate 21 is slidably connected inside the crushing box 3, a plurality of transmission rollers 12 are rotatably connected inside the mixing box 2, stirring blades 13 are fixed at the top and bottom of the outer side of the transmission roller 12, a discharge port 11 is fixed at the other end of the outer bottom of the mixing box 2, and a closing plate 22 is slidably connected inside the discharge port 11.

[0023] The present invention provides a mixing device for producing metformin. First, the staff turns on the power of the device, and then places the raw materials to be produced of metformin into the inside of the feed port 5, and then slides the filter plate 21 to evenly disperse the raw materials for metformin production, thereby promoting the mixing effect of the metformin raw materials, and then rotates the transmission roller 12 and the stirring blade 13 to deeply mix the metformin raw materials, and finally pulls the closing plate 22 to separate from the discharge port 11, so that the mixed metformin raw materials are discharged from the discharge port 11.

[0024] In order to enable those skilled in the art to better understand the solutions of the present invention, the technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the accompanying drawings.

[0025] It should be noted that, in the absence of conflict, the embodiments of the present invention and the features and technical solutions in the embodiments may be combined with each other.

[0026] It should be noted that similar reference numerals and letters denote similar items in the following drawings, and therefore, once an item is defined in one drawing, further definition and explanation thereof is not required in subsequent drawings.

[0027] Embodiment 1 Please refer to Figure 1-Figure 5A mixing device for metformin production includes a mixing box 2 as a main container for mixing metformin raw materials. The mixing box 2 is designed to allow the raw materials to be fully mixed therein to ensure the consistency and quality of the product. A crushing box 3 is fixed at one end of the mixing box 2. The crushing box 3 is used to preliminarily crush and break up the metformin raw materials, especially for those raw materials that may accumulate into blocks. A feed port 5 is opened at the top of the crushing box 3. A filter plate 21 is slidably connected inside the crushing box 3, which is slidably connected inside the crushing box 3 to further break up and evenly distribute the metformin raw materials. The material is mixed and the broken metformin raw materials are screened. A plurality of transmission rollers 12 are rotatably connected inside the mixing box 2. A stirring blade 13 is fixed to the top and bottom of the outer side of the transmission roller 12. A discharge port 11 is fixed to the other end of the outer bottom of the mixing box 2. A closing plate 22 is slidably connected to the inner side of the discharge port 11. The discharge port 11 is located at the other end of the outer bottom of the mixing box 2 and is used to discharge the mixed metformin raw materials. The closing plate 22 is slidably connected to the inner side of the discharge port 11 and is used to control the opening and closing of the discharge port. Support feet 6 are fixed to both sides of the bottom of the mixing box 2. When in use, the staff first turns on the power of the device, and then places the raw materials to be produced by metformin into the inside of the feed port 5, and then slides the filter plate 21 to evenly disperse the raw materials for metformin production, thereby promoting the mixing effect of the metformin raw materials, and then rotates the transmission roller 12 and the stirring blade 13 to deeply mix the metformin raw materials, and finally pulls the closing plate 22 to separate from the discharge port 11, so that the mixed metformin raw materials are discharged from the discharge port 11; A reciprocating drive mechanism for driving the filter plate 21 to vibrate is arranged inside the crushing box 3, and the reciprocating drive mechanism includes a servo motor 27, a transmission rod 18, a driving rod 19, a linkage rod 17 and a driving rod 19. Guide grooves 9 are provided at both ends of the crushing box 3, and the inner side of the guide groove 9 is slidably connected to the filter plate 21. The guide grooves 9 are arranged at both ends of the crushing box 3 to guide the sliding and vibration of the filter plate 21. The interior of the crushing box 3 is rotatably connected with the transmission rod 18, and both ends of the outer side of the transmission rod 18 are rotatably connected with the driving rod 19. The end of the driving rod 19 away from the transmission rod 18 is rotatably connected with the linkage rod 17, and the end of the linkage rod 17 away from the driving rod 19 is rotatably connected with the filter plate 21. A servo motor 27 is fixed at one end of the crushing box 3, and the output end of the servo motor 27 passes through the crushing box 3 and is fixed to the transmission rod 18. The servo motor 27 drives the transmission rod 18 to rotate, and then through the transmission of the driving rod 19 and the linkage rod 17, the filter plate 21 vibrates up and down along the guide inside the guide groove 9. This vibration helps to break up the accumulated raw materials and improve the mixing effect; Specifically, when it is necessary to break up the raw materials of metformin that have accumulated into blocks, so as to further promote the mixing effect of metformin, the servo motor 27 is started to drive the transmission rod 18 to rotate, and the transmission rod 18 drives the driving rod 19 and the linkage rod 17 to reciprocate, so that the linkage rod 17 drives the filter plate 21 to reset and vibrate up and down along the guide inside the guide groove 9, so as to evenly break up the accumulated metformin raw materials, thereby greatly increasing the mixing effect of the device; Embodiment 2 Please refer to Figure 6-Figure 8 A mixing device for metformin production, wherein a guide block 20 is fixed at the bottom of a crushing box 3, and finally the evenly dispersed metformin raw material is guided to the inside of a mixing box 2 along the guide block 20. The design of the guide block 20 ensures a smooth transition of the raw material from the crushing box 3 to the mixing box 2, avoiding the accumulation of the raw material during the transfer process, thereby improving the production efficiency; The mixing box 2 is provided with a driving mechanism for driving the transmission roller 12 and the stirring blade 13 to move. The driving mechanism includes an internal gear 14, a planetary gear 15 and a transmission wheel 16. The internal gear 14 is fixed to the top of the mixing box 2. The internal gear 14 is meshed with the planetary gear 15 to achieve smooth transmission and conversion of power, so that the planetary gear 15 can rotate and revolve along its inner side, thereby driving the transmission roller 12 and the stirring blade 13 to perform mixing operations; The top of the mixing box 2 is rotatably connected with a transmission wheel 16, and the outer side of the transmission wheel 16 is meshedly connected with a plurality of planetary gears 15. The planetary gears 15 are provided at the top of the mixing box 2 to guide the rotation and revolution of the planetary gears 15 and ensure the stability and accuracy of their movement. The outer side of the planetary gears 15 is meshedly connected with the internal gear 14. An annular guide rail is provided at the top of the mixing box 2, and the top of the planetary gears 15 is slidably connected with the annular guide rail. A servo motor 4 is fixed to the top of the mixing box 2, and a worm is fixed to the output end of the servo motor 4. The top of the mixing box 2 is rotatably connected with a worm wheel 8, and the bottom end of the worm wheel 8 is fixed to the transmission wheel 16, and the outer side of the worm is meshedly connected with the worm wheel 8. Specifically, when the broken up metformin raw material is introduced into the mixing box 2, the servo motor 4 is started to drive the worm and the worm gear 8 to rotate, and the worm gear 8 drives the transmission wheel 16 to rotate, and the transmission wheel 16 drives the three planetary gears 15 to move, so that the three planetary gears 15 rotate and rotate along the inner side of the internal gear 14, so that the planetary gears 15 drive the transmission roller 12 and the stirring blade 13 to mix the metformin raw material inside the mixing box 2, and the three planetary gears 15 rotate as a whole, thereby greatly increasing the mixing effect of the transmission roller 12 and the stirring blade 13 on the metformin raw material; Embodiment 3 Please refer to Fig. 9 and Fig.10 , a mixing device for metformin production, a lifting mechanism for tilting the mixing box 2 is arranged at the bottom end of the crushing box 3, the lifting mechanism comprises a base 1, a hydraulic rod 10 and a linkage rod 17, one end of the bottom end of the base 1 is rotatably connected with the hydraulic rod 10, the output end of the hydraulic rod 10 is rotatably connected with the crushing box 3, the other end of the base 1 is fixed with a linkage rod 17, the inner side of the linkage rod 17 is rotatably connected with the mixing box 2, as the basic supporting structure of the entire lifting mechanism, carrying the hydraulic rod 10, the linkage rod 17 and the crushing box 3 and the mixing box 2 connected thereto, the stability of the base 1 ensures the stability and safety of the lifting mechanism during operation, and provides reliable support for other components; One end of the base 1 is installed at the bottom and connected to the crushing box 3 through a rotating connection. As the power source of the lifting mechanism, the telescopic movement of the hydraulic rod 10 realizes the lifting and tilting operation of the crushing box 3 and the mixing box 2. Its high-precision control ensures the accuracy and stability of the lifting angle, thereby meeting the requirements for the discharge of the metformin raw materials after mixing; Specifically, after the driving roller 12 and the stirring blade 13 deeply mix the metformin raw material, the mixed metformin needs to be discharged, and then the closing plate 22 is pulled to disengage from the discharge port 11 for discharge. In order to improve the cleanliness of the metformin discharge inside the mixing box 2, the hydraulic rod 10 is started to drive the crushing box 3 and the mixing box 2 and the linkage rod 17 to rotate, so that the mixing box 2 and the discharge port 11 are tilted, so as to improve the cleanliness of the discharge of the mixed metformin raw material on the mixing box 2 side.

[0028] The use process of a mixing device for producing metformin provided by the present invention is as follows: first, the staff turns on the power of the device, and then places the raw materials to be produced by metformin into the inside of the feed port 5, starts the servo motor 27 to drive the transmission rod 18 to rotate, and the transmission rod 18 drives the driving rod 19 and the linkage rod 17 to reciprocate, so that the linkage rod 17 drives the filter plate 21 to reset and vibrate up and down along the guide inside the guide groove 9, so as to evenly disperse the accumulated metformin raw materials; The broken up metformin raw material is introduced into the mixing box 2, and then the servo motor 4 is started to drive the worm and the worm gear 8 to rotate, and the worm gear 8 drives the transmission wheel 16 to rotate, and the transmission wheel 16 drives the three planetary gears 15 to move, so that the three planetary gears 15 rotate along the inner side of the internal gear 14, so that the planetary gears 15 drive the transmission roller 12 and the stirring blade 13 to mix the metformin raw material inside the mixing box 2; Finally, the closing plate 22 is pulled away from the discharge port 11 to discharge the mixed metformin raw material, thereby starting the hydraulic rod 10 to drive the crushing box 3, the mixing box 2 and the linkage rod 17 to rotate, so that the mixing box 2 and the discharge port 11 are tilted, so as to improve the cleanliness of the discharge of the mixed metformin raw material on the mixing box 2 side.

[0029] The preferred embodiments of the present invention disclosed above are only used to help explain the present invention. The preferred embodiments do not describe all the details in detail, nor do they limit the present invention to specific implementation methods. Obviously, many modifications and changes can be made according to the content of this specification. This specification selects and specifically describes these embodiments in order to better explain the principles and practical applications of the present invention, so that those skilled in the art can understand and use the present invention well. The present invention is limited only by the claims and their full scope and equivalents.

Claims

1. A mixing device for metformin production, characterized in that: The invention comprises a mixing box (2), a crushing box (3) being fixed at one end of the mixing box (2), a feeding port (5) being provided at the top end of the crushing box (3), a filter plate (21) being slidably connected to the inside of the crushing box (3), a plurality of transmission rollers (12) being rotatably connected to the inside of the mixing box (2), stirring blades (13) being fixed to the top and bottom ends of the outer sides of the transmission rollers (12), and a discharge port (11) being fixed to the other end of the outer bottom end of the mixing box (2).

2. A mixing device for metformin production according to claim 1, characterized in that: A reciprocating drive mechanism for driving the filter plate (21) to vibrate is arranged inside the crushing box (3), the reciprocating drive mechanism comprising a second servo motor (7), a transmission rod (18), a drive rod (19), a linkage rod (17) and a drive rod (19), guide grooves (9) are provided at both ends of the crushing box (3), and the inner side of the guide groove (9) is slidably connected to the filter plate (21).

3. A mixing device for metformin production according to claim 2, characterized in that: A transmission rod (18) is rotatably connected inside the crushing box (3), and both ends of the outer side of the transmission rod (18) are rotatably connected to driving rods (19), and one end of the driving rod (19) away from the transmission rod (18) is rotatably connected to a linkage rod (17), and one end of the linkage rod (17) away from the driving rod (19) is rotatably connected to a filter plate (21).

4. A mixing device for metformin production according to claim 3, characterized in that: A servo motor 2 (7) is fixed to one end of the crushing box (3), and an output end of the servo motor 2 (7) passes through the crushing box (3) and is fixed to a transmission rod (18).

5. A mixing device for producing metformin according to claim 4, characterized in that: A material guide block (20) is fixed at the bottom end of the crushing box (3).

6. A mixing device for producing metformin according to claim 2, characterized in that: A driving mechanism for driving the transmission roller (12) and the stirring blade (13) to move is arranged inside the mixing box (2), and the driving mechanism comprises an internal gear (14), a planetary gear (15) and a transmission wheel (16). The internal gear (14) is fixed to the top of the mixing box (2), and the transmission wheel (16) is rotatably connected to the top of the mixing box (2). The outer side of the transmission wheel (16) is meshedly connected to a plurality of planetary gears (15), and the outer side of the planetary gear (15) is meshedly connected to the internal gear (14).

7. A mixing device for producing metformin according to claim 6, characterized in that: An annular guide rail is provided at the top end of the mixing box (2), and the top end of the planetary gear (15) is slidably connected to the annular guide rail.

8. A mixing device for producing metformin according to claim 6, characterized in that: A servo motor 1 (4) is fixed to the top of the mixing box (2), a worm is fixed to the output end of the servo motor 1 (4), a worm wheel (8) is rotatably connected to the top of the mixing box (2), the bottom end of the worm wheel (8) is fixed to a transmission wheel (16), and the outer side of the worm is meshingly connected to the worm wheel (8).

9. A mixing device for producing metformin according to claim 2, characterized in that: A lifting mechanism for tilting the mixing box (2) is provided at the bottom end of the crushing box (3), the lifting mechanism comprising a base (1), a hydraulic rod (10) and a linkage rod (17); one end of the bottom end of the base (1) is rotatably connected to the hydraulic rod (10); the output end of the hydraulic rod (10) is rotatably connected to the crushing box (3); the other end of the base (1) is fixed with a linkage rod (17); the inner side of the linkage rod (17) is rotatably connected to the mixing box (2).

10. A mixing device for producing metformin according to claim 1, characterized in that: A closing plate (22) is slidably connected to the inner side of the discharge port (11), and supporting feet (6) are fixed to both sides of the bottom end of the mixing box (2).

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