Implanted micropump driving system and driving method for glaucoma treatment

Abstract

The invention discloses an implanted micropump driving system and method for glaucoma treatment, and relates to the field of driving systems.The driving system comprises a receiving coil, a power management module, a microprocessor control module and a driving module, the receiving coil is connected with the power management module, and the microprocessor control module is connected with the driving module; the power supply management module is respectively connected with the microprocessor control module and the driving module, and the microprocessor control module is connected with the driving module; the driving method comprises the following steps that the receiving coil receives energy of the transmitting coil, the power management module converts the energy into a stable power supply voltage signal and transmits the power supply voltage signal to the microprocessor control module and the driving module, and the microprocessor control module generates an analog signal and a control signal; the driving module processes the analog signal and the control signal, outputs a high-voltage square wave signal, and drives the piezoelectric micropump through the high-voltage square wave signal; secondary injury to the patient is reduced, the micropump is accurately controlled, and the intraocular pressure of the glaucoma patient is effectively reduced.

Description

Technical Field

[0001] The present invention relates to the field of driving systems, and in particular to an implantable micropump driving system and a driving method for treating glaucoma. Background Art

[0002] Glaucoma is a chronic progressive optic neuropathy characterized by damage to the optic disc and retinal nerve fiber layer. It is one of the leading diseases of irreversible blindness worldwide. The disease is mainly caused by blockage of the trabecular meshwork to Schlemm's canal during the circulation of aqueous humor in the eye, which causes accumulation of aqueous humor, increased intraocular pressure, deformation of the eyeball, indirect compression of the retina and damage to the optic nerve, resulting in a narrowed field of vision, impaired vision, and may eventually lead to blindness.

[0003] Active drainage of aqueous humor using a biological micropump is an innovative treatment option that can effectively drain the aqueous humor and reduce intraocular pressure by accurately controlling the micropump in real time through an implantable micropump drive system.

[0004] In the prior art, for example, in the research and experiments on the drive control system of a dual-cavity piezoelectric pump, the drive system can generate an AC signal of 0-400Hz, and the voltage range is set to be adjustable at 0-110V; in the research and experiments on the digital control drive power supply of the dual active valve piezoelectric pump DAVPP, the drive system uses digital synthesis technology to generate two sinusoidal signals with adjustable frequency and phase difference, uses a T-type resistor network to adjust the voltage, and uses high voltage and power amplification units to achieve sufficient driving capability. The power supply outputs a maximum voltage of 175V, a frequency range of 5-500Hz, a minimum resolution of 1Hz, and a phase difference that can be adjusted from 0° to 360°, with a minimum resolution of 11.25°.

[0005] However, the output voltage and system area of ​​this type of drive system are too large. The excessive output voltage will lead to increased energy consumption and higher electricity costs, and the excessively large drive system area will lead to increased inertia, making it difficult to achieve fast and precise control. It is not suitable for driving implantable piezoelectric micropumps for glaucoma treatment.

[0006] Therefore, an implantable micropump driving system and a driving method for treating glaucoma are provided to solve the above problems. Summary of the invention

[0007] The purpose of the present invention is to provide an implantable micropump drive system and drive method for glaucoma treatment, which can achieve low power consumption, low voltage and current output, accurately control the micropump, effectively reduce the intraocular pressure of glaucoma patients, reduce secondary damage to patients, improve safety, and at the same time miniaturize the volume to reduce costs.

[0008] To achieve the above-mentioned purpose, the present invention provides an implantable micropump driving system and driving method for glaucoma treatment, including a receiving coil, a power management module, a microprocessor control module and a driving module, the receiving coil is connected to the power management module, the power management module is respectively connected to the microprocessor control module and the driving module, and the microprocessor control module is connected to the driving module.

[0009] Preferably, the overall volume of the receiving coil, the power management module, the microprocessor control module and the driving module is set to 15mm×15mm×3mm.

[0010] Preferably, the power management module includes a rectifier circuit and an LDO chip.

[0011] Preferably, the microprocessor control module includes a Bluetooth module, a microprocessor and a low-pass filter, and the core of the microprocessor is set to an ARMCortex-M4 core.

[0012] A driving method of an implantable micropump driving system for treating glaucoma, comprising the following steps: S1: The receiving coil receives the energy from the transmitting coil and transmits the energy to the power management module; S2: The power management module converts the energy into a stable power supply voltage signal, and transmits the stable power supply voltage signal to the microprocessor control module and the drive module; S3: The microprocessor control module generates an analog signal and a control signal, and transmits the analog signal and the control signal to the drive module; S4: The driving module processes the analog signal and the control signal, outputs a high-voltage square wave signal, and drives the piezoelectric micropump through the high-voltage square wave signal.

[0013] Preferably, step S2 specifically includes the following steps: S21: The power management module converts energy into an unstable DC voltage signal through a rectifier circuit, and transmits the unstable DC voltage signal to the LDO chip; S22: The LDO chip stabilizes the unstable DC voltage signal into a stable power supply voltage signal.

[0014] Preferably, step S3 specifically includes the following steps: S31: After the microprocessor control module receives the stable power supply voltage signal, the Bluetooth module receives the parameters sent by the remote terminal through the Bluetooth protocol; S32: The microprocessor generates a PWM signal and a control signal based on the parameters sent by the remote terminal, and transmits the PWM signal to a low-pass filter; S33: low-pass filter converts the PWM signal into an analog signal; S34: The microprocessor transmits the control signal to the driving module, and the low-pass filter transmits the analog signal to the driving module.

[0015] Preferably, in step S4, the output frequency of the high voltage square wave signal is set to 10-50 Hz, and the output voltage of the high voltage square wave signal is set to ±20V.

[0016] Therefore, the present invention adopts the above-mentioned implantable micropump driving system and driving method for glaucoma treatment, which has the following beneficial effects: (1) The receiving coil of the present invention is a wireless energy coil, which is powered by the wireless energy coil. There is no need to replace the battery after implantation, which can reduce secondary damage to the patient; (2) The present invention receives parameters sent by a remote terminal through the Bluetooth protocol and generates a driving signal according to the parameters, which can accurately control the micropump and effectively reduce the intraocular pressure of glaucoma patients; (3) The overall volume of the present invention is small, easy to implant, and low in cost; (4) The driving system of the present invention has low power consumption, low output voltage, low current and high safety.

[0017] The method scheme of the present invention is further described in detail below through the drawings and embodiments. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 This is a structural diagram of an implantable micropump driving system for treating glaucoma according to the present invention; Figure 2 A flow chart of a driving method of an implantable micropump driving system for treating glaucoma according to the present invention; Figure 3 is a functional flow chart of the power management module of the present invention; Figure 4 It is a functional flow chart of the microprocessor control module of the present invention.

[0019] Among them: 1. receiving coil; 2. power management module; 201. rectifier circuit; 202. LDO chip; 3. microprocessor control module; 301. Bluetooth module; 302. microprocessor; 303. low-pass filter; 4. driving module. DETAILED DESCRIPTION

[0020] The method scheme of the present invention is further described below through drawings and embodiments.

[0021] Unless otherwise defined, method terms or scientific terms used in the present invention shall have the common meanings understood by one of ordinary skill in the art to which the present invention belongs.

[0022] The words "include" or "comprises" and the like used in the present invention mean that the elements before the word include the elements listed after the word, and do not exclude the possibility of also including other elements. The orientation or position relationship indicated by the terms "inside", "outside", "upper", "lower", etc. is based on the orientation or position relationship shown in the drawings, which is only for the convenience of describing the present invention and simplifying the description, and does not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation. Therefore, it cannot be understood as a limitation of the present invention. When the absolute position of the described object changes, the relative position relationship may also change accordingly. In the present invention, unless otherwise clearly specified and limited, the terms "attachment" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral body; it can be directly connected, or indirectly connected through an intermediate medium, and it can be the internal connection of two elements or the interaction relationship between two elements. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0023] Example like Figure 1 As shown, the present invention provides an implantable micropump driving system for treating glaucoma, including a receiving coil 1, a power management module 2, a microprocessor control module 3 and a driving module 4, wherein the receiving coil 1 is connected to the power management module 2, the power management module 2 is respectively connected to the microprocessor control module 3 and the driving module 4, and the microprocessor control module 3 is connected to the driving module 4.

[0024] The overall volume of the receiving coil 1, the power management module 2, the microprocessor control module 3 and the driving module 4 is set to 15 mm×15 mm×3 mm.

[0025] The power management module 2 includes a rectifier circuit 201 and an LDO chip 202 .

[0026] The microprocessor control module 3 includes a Bluetooth module 301 , a microprocessor 302 and a low-pass filter 303 . The core of the microprocessor 302 is set to be an ARM Cortex-M4 core.

[0027] The circuit principle of the driving module 4 chip includes a boost circuit and an analog amplifier circuit.

[0028] like Figure 2 As shown, a driving method of an implantable micropump driving system for glaucoma treatment comprises the following steps: S1: The receiving coil receives the energy of the transmitting coil and transmits the energy to the power management module, providing input for the power management module; S2: The power management module converts the energy into a stable power supply voltage signal, and transmits the stable power supply voltage signal to the microprocessor control module and the drive module to power the system; like Figure 3 As shown, step S2 specifically includes the following steps: S21: The power management module converts energy into an unstable DC voltage signal through a rectifier circuit, and transmits the unstable DC voltage signal to the LDO chip; S22: The LDO chip stabilizes the unstable DC voltage signal into a stable power supply voltage signal.

[0029] S3: The microprocessor control module generates an analog signal and a control signal, and transmits the analog signal and the control signal to the driving module as an input signal of the driving module; like Figure 4 As shown, step S3 specifically includes the following steps: S31: After the microprocessor control module receives the stable power supply voltage signal, the Bluetooth module receives the parameters sent by the remote terminal through the Bluetooth protocol; S32: The microprocessor generates a PWM signal and a control signal based on the parameters sent by the remote terminal, and transmits the PWM signal to the low-pass filter through the general IO port; S33: low-pass filter converts the PWM signal into an analog signal; S34: The microprocessor transmits the control signal to the driving module, and the low-pass filter transmits the analog signal to the driving module.

[0030] S4: The driving module processes the analog signal and the control signal, outputs a high-voltage square wave signal through the output pin, and drives the piezoelectric micro pump through the high-voltage square wave signal; In step S4, the output frequency of the high voltage square wave signal is set to 10-50 Hz, and the output voltage of the high voltage square wave signal is set to ±20V.

[0031] Therefore, the present invention adopts the above-mentioned implantable micropump driving system and driving method for glaucoma treatment to achieve low power consumption, low voltage and current output, accurately control the micropump, effectively reduce the intraocular pressure of glaucoma patients, reduce secondary damage to patients, improve safety, and at the same time miniaturize the volume to reduce costs.

[0032] Finally, it should be noted that the above embodiments are only used to illustrate the method scheme of the present invention rather than to limit it. Although the present invention has been described in detail with reference to the preferred embodiments, ordinary method personnel in the field should understand that they can still modify or replace the method scheme of the present invention with equivalents, and these modifications or equivalent replacements cannot cause the modified method scheme to deviate from the spirit and scope of the method scheme of the present invention.

Claims

1. An implantable micropump drive system for treating glaucoma, characterized in that: It includes a receiving coil, a power management module, a microprocessor control module and a driving module. The receiving coil is connected to the power management module, the power management module is respectively connected to the microprocessor control module and the driving module, and the microprocessor control module is connected to the driving module.

2. The implantable micropump driving system for glaucoma treatment according to claim 1, characterized in that: The overall volume of the receiving coil, power management module, microprocessor control module and driving module is set to 15mm×15mm×3mm.

3. The implantable micropump driving system for glaucoma treatment according to claim 1, characterized in that: The power management module includes a rectifier circuit and an LDO chip.

4. The implantable micropump driving system for treating glaucoma according to claim 1, characterized in that: The microprocessor control module includes a Bluetooth module, a microprocessor and a low-pass filter, and the core of the microprocessor is set to be an ARMCortex-M4 core.

5. A driving method for an implantable micropump driving system for treating glaucoma according to any one of claims 1 to 4, characterized in that: The following steps are involved: S1: The receiving coil receives the energy from the transmitting coil and transmits the energy to the power management module; S2: The power management module converts the energy into a stable power supply voltage signal, and transmits the stable power supply voltage signal to the microprocessor control module and the drive module; S3: The microprocessor control module generates an analog signal and a control signal, and transmits the analog signal and the control signal to the drive module; S4: The driving module processes the analog signal and the control signal, outputs a high-voltage square wave signal, and drives the piezoelectric micropump through the high-voltage square wave signal.

6. The driving method of the implantable micropump driving system for glaucoma treatment according to claim 5, characterized in that: Step S2 specifically includes the following steps: S21: The power management module converts energy into an unstable DC voltage signal through a rectifier circuit, and transmits the unstable DC voltage signal to the LDO chip; S22: The LDO chip stabilizes the unstable DC voltage signal into a stable power supply voltage signal.

7. The driving method of the implantable micropump driving system for glaucoma treatment according to claim 5, characterized in that: Step S3 specifically includes the following steps: S31: After the microprocessor control module receives the stable power supply voltage signal, the Bluetooth module receives the parameters sent by the remote terminal through the Bluetooth protocol; S32: The microprocessor generates a PWM signal and a control signal based on the parameters sent by the remote terminal, and transmits the PWM signal to a low-pass filter; S33: low-pass filter converts the PWM signal into an analog signal; S34: The microprocessor transmits the control signal to the driving module, and the low-pass filter transmits the analog signal to the driving module.

8. The driving method of the implantable micropump driving system for glaucoma treatment according to claim 5, characterized in that: In step S4, the output frequency of the high voltage square wave signal is set to 10-50 Hz, and the output voltage of the high voltage square wave signal is set to ±20V.

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