Integrated monitoring kneecap device based on intelligent nanometer novel medicine

Abstract

The invention discloses an integrated monitoring kneepad device based on intelligent nano novel drugs, which is of an axially extending cylindrical structure and is divided into a thigh section, a knee section and a shank section along the axis of the lower limb of a human body, and the thigh section and the shank section are respectively provided with a bridle. Comprising a thigh bearing piece, a shank bearing piece, an angle sensor, a flexible patch temperature sensor and a plurality of microneedle patches, the thigh bearing piece is arranged on the thigh section, the shank bearing piece is arranged on the shank section, one end of the thigh bearing piece and one end of the shank bearing piece intersect and are hinged at the knee section, the angle sensor is arranged on a rotating shaft at the hinged position, and the flexible patch temperature sensor is arranged on the rotating shaft. The flexible patch temperature sensor is arranged on the knee section, and the microneedle patches are arranged on the thigh section and the shank section respectively. Therefore, the angle sensor, the flexible patch temperature sensor and the microneedle patch can be integrated, the bending angle of the knee joint is collected in real time, local temperature changes are continuously monitored, and intelligent nano-drugs are directionally released to an acupuncture point area.

Description

Technical Field

[0001] The present invention relates to the field of medical devices, and particularly refers to an integrated monitoring knee brace device based on intelligent nano new drugs. Background Art

[0002] Currently, common knee brace devices on the market mostly use physical fixation or elastic material support, mainly to limit the range of joint movement or relieve local pressure. Some products attempt to integrate basic sensors or drug patches for auxiliary monitoring or treatment. However, there are still some problems in the functional integration and coordination of existing devices. For example, the monitoring module is usually independent of the treatment module, making it difficult to achieve data-driven real-time intervention. Traditional drug patches rely on passive diffusion and are difficult to accurately act on deep tissues or specific acupoints. In addition, the mechanical compatibility between the physical support structure and the sensing unit is insufficient, which may affect the comfort and monitoring accuracy of long-term wearing. Therefore, developing an integrated knee brace device that can take into account dynamic monitoring, intelligent warning, and targeted treatment is of practical significance for improving the rehabilitation effect of the knee joint. Summary of the Invention

[0003] The present invention aims to solve at least to some extent the technical problems in the above-mentioned technology.

[0004] To this end, the present invention discloses an integrated monitoring knee brace device based on intelligent nano new drugs, which has an axially extending cylindrical structure and is divided into a thigh section, a knee section, and a calf section along the axis of the human lower limb. The thigh section and the calf section are respectively provided with straps. In addition, it includes: a thigh support member, a calf support member, an angle sensor, a flexible patch temperature sensor, and a plurality of microneedle patches. Among them, the thigh support member is arranged in the thigh section, the calf support member is arranged in the calf section, one end of the thigh support member and one end of the calf support member meet and are hinged at the knee section, the angle sensor is arranged on the rotating shaft at the hinge, the flexible patch temperature sensor is arranged on the knee section, and the microneedle patches are respectively arranged on the thigh section and the calf section.

[0005] According to the integrated monitoring knee brace device based on intelligent nano new drugs disclosed by the present invention, through the cylindrical structure design, the angle sensor, the flexible patch temperature sensor, and the microneedle patches can be integrated. The angle sensor can continuously collect the bending angle of the knee joint and trigger an alarm when it exceeds a preset value. The flexible patch temperature sensor is attached to the surface of the knee section to continuously monitor the local temperature change and timely warn of the risk of inflammation or infection. The microneedle patches are distributed on the thigh section and the calf section. By virtue of the characteristic that the microneedles penetrate the stratum corneum, the intelligent nano drugs can be directionally released to the acupoint area to improve the drug penetration efficiency.

[0006] In addition, the integrated monitoring knee brace device based on intelligent nano new drugs disclosed by the present invention may also have the following additional technical features:

[0007] In one embodiment of the present invention, annular silicone anti-slip patterns are respectively provided on the inner wall of the thigh section and the inner wall of the calf section.

[0008] In one embodiment of the present invention, the thigh support member and the thigh section are connected by hot melting, and the calf support member and the calf section are connected by hot melting.

[0009] In one embodiment of the present invention, the thigh support member and the calf support member are respectively L-shaped aluminum parts.

[0010] In one embodiment of the present invention, the thigh section and the calf section are respectively provided with hollowings, and the microneedle patch is embedded in the hollowings through tenons.

[0011] In one embodiment of the present invention, the microneedle patch covers acupoints including but not limited to Xuehai (SP10), Liangqiu (ST34), Dubi (ST35), Yanglingquan (GB34) and Zusanli (ST36).

[0012] Additional content and advantages of the present invention will be given in the following description, or understood through the practice of the present invention. BRIEF DESCRIPTION OF THE DRAWINGS

[0013] The technical solutions and beneficial effects of the present invention will become obvious and easy to understand from the following content in conjunction with the drawings, where:

[0014] Figure 1 is a schematic structural diagram of an integrated monitoring knee guard device based on intelligent nano new drugs of the present invention;

[0015] Figure 2 is a schematic structural diagram of an integrated monitoring knee guard device based on intelligent nano new drugs of the present invention;

[0016] Figure 3 is a schematic structural diagram of an integrated monitoring knee guard device based on intelligent nano new drugs of the present invention;

[0017] Figure 4 is a schematic structural diagram of an integrated monitoring knee guard device based on intelligent nano new drugs of the present invention;

[0018] As shown in the figure:

[0019] 1 - thigh section;

[0020] 2 - knee section;

[0021] 3 - calf section;

[0022] 4 - strap;

[0023] 5 - thigh support member;

[0024] 6 - Calf support member;

[0025] 7 - Angle sensor;

[0026] 8 - Flexible patch temperature sensor;

[0027] 9 - Microneedle patch. Detailed implementation manners

[0028] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all of the embodiments.

[0029] Next, an integrated monitoring knee brace device based on intelligent nano - new drugs disclosed in the present invention will be described with reference to the accompanying drawings. Hereinafter, it is simply referred to as the "knee brace device";

[0030] As Figure 1 , Figure 2 , Figure 3 and Figure 4 shown, an integrated monitoring knee brace device based on intelligent nano - new drugs has an axially extending cylindrical structure. It is divided into a thigh section 1, a knee section 2, and a calf section 3 along the axis of the human lower limb. Straps 4 are respectively provided on the thigh section 1 and the calf section 3. In addition, it includes: a thigh support member 5, a calf support member 6, an angle sensor 7, a flexible patch temperature sensor 8, and a plurality of microneedle patches 9. Among them, the thigh support member 5 is provided on the thigh section 1, the calf support member 6 is provided on the calf section 3, one end of the thigh support member 5 and one end of the calf support member 6 meet and are hinged at the knee section 2, the angle sensor 7 is provided on the rotating shaft at the hinge, the flexible patch temperature sensor 8 is provided on the knee section 2, and the microneedle patches 9 are respectively provided on the thigh section 1 and the calf section 3;

[0031] It should be noted that the knee brace device disclosed in the present invention can work in cooperation with a cloud platform;

[0032] The cloud platform includes the following core modules, which cooperate with the knee brace device to realize functions of data collection, analysis, early warning, and remote management:

[0033] Data collection and transmission module. The knee brace device is connected to a user terminal (such as a smart phone) through Bluetooth / Wi - Fi, and uploads the following data to the cloud platform in real - time. Specifically, the knee joint bending angle (collected by the angle sensor), local temperature data (collected by the flexible patch temperature sensor), and microneedle patch drug release records (including time, dose, and target acupoints). And data encryption uses the AES - 256 protocol to ensure transmission security;

[0034] Data analysis and intelligent warning module. For the analysis of the dynamic knee bending angle threshold, a preset safe knee bending angle range (such as 0° - 60°) is set. When the threshold is exceeded, an alarm is triggered and pushed to the user and doctor terminals. For temperature anomaly monitoring, the temperature data of the knee segment is continuously analyzed. If the temperature continuously exceeds the baseline value (such as 37.5°C), it is determined as an inflammation risk and a warning notice is generated.

[0035] Drug management module. In terms of dosage control, according to the characteristics of acupoints (such as Xuehai acupoint, Zusanli acupoint) and the patient's weight, the drug release dosage is intelligently recommended. In terms of release record tracking, the time, acupoint location, and dosage of each drug release are recorded, and a visual report is generated for doctors' reference. In terms of remote control function, doctors can adjust the drug release plan through the cloud platform to optimize the treatment plan.

[0036] User interaction interface. The patient-side APP of the cloud platform real-time displays the knee joint activity status, temperature trend, and drug release record, and supports manual triggering of emergency alarms. For the doctor-side management platform, it provides a multi-patient data dashboard, supports remote diagnosis, prescription adjustment, and rehabilitation plan formulation. Finally, a family member sharing function is integrated, authorizing family members to view the patient's key health indicators for convenient collaborative care.

[0037] The data of the angle sensor 7 and the flexible patch temperature sensor 8 are transmitted to the user terminal through the low-power transmission module. The terminal is encrypted using AES-256 and then uploaded to the cloud platform. The data packet interval is 1 second (activity monitoring mode) or 10 seconds (rest mode).

[0038] The cloud platform presets the safe knee bending threshold to 0° to 60°. When exceeded, a level 3 alarm (vibration, sound, APP push) is triggered. The temperature baseline value is dynamically calibrated according to the user's daily body temperature. If the temperature exceeds 37.5°C continuously for 3 times (with an interval of 10 minutes), it is determined as an inflammation risk.

[0039] The cloud platform generates a drug release plan based on the user's weight (input to the APP) and the characteristics of acupoints (such as an additional 10% dosage for Zusanli acupoint). The doctor side can remotely adjust the parameters (such as changing the release cycle from 6 hours to 4 hours). The system automatically generates a medication report (in PDF / Excel format) and synchronizes it to multiple terminals.

[0040] The power supply system of the knee guard device is integrated inside the knee segment 2, using a flexible lithium battery (thickness 1.2mm, capacity 200mAh). The battery life is 72 hours (normal mode) or 48 hours (high-precision monitoring mode). The charging interface is a magnetic Type-C, supporting wireless charging (Qi protocol). When charging, it automatically switches to the low-power state to ensure usage safety.

[0041] The inner walls of the thigh segment 1 and the calf segment 3 are respectively provided with annular silicone anti-slip patterns.

[0042] It should be noted that the inner walls of the thigh section 1 and the calf section 3 are respectively provided with annular silicone anti-slip patterns; the spacing of the anti-slip patterns is 3-5 mm, the depth is 1-2 mm, and they are made of medical-grade silicone material. The surface is treated with a nano-coating to enhance friction and reduce the risk of skin allergy; the symmetrical distribution of the annular patterns can evenly disperse the contact pressure between the knee brace and the skin, avoiding blood circulation disorders caused by long-term wearing.

[0043] The thigh support member 5 and the thigh section 1 are connected by hot melt welding, and the calf support member 6 and the calf section 3 are connected by hot melt welding.

[0044] It should be noted that the thigh support member 5 and the thigh section 1 are connected by hot melt welding, and the calf support member 6 and the calf section 3 are connected by the same process. The hot melt welding temperature is 180-200 °C, and the welding time is 20-30 seconds to ensure that there is no gap between the bonding surface of the polymer material (such as TPU or nylon composite material) and the support member. After the welding is completed, a tensile strength test (≥50 N / mm2) is carried out at the interface to meet the durability standard of medical devices.

[0045] The thigh support member 5 and the calf support member 6 are respectively L-shaped aluminum parts.

[0046] It should be noted that the thigh support member 5 and the calf support member 6 are respectively L-shaped aluminum parts, made of 6061-T6 aluminum alloy material, and the surface is anodized to improve corrosion resistance. The vertical side height of the L-shaped structure is 15-20 mm, the horizontal side width is 8-10 mm, and the corner is designed with an arc (R = 2 mm) to avoid stress concentration and match the rotating shaft at the hinge to ensure no mechanical interference within the knee joint movement range (0°-150°).

[0047] The thigh section 1 and the calf section 3 are respectively provided with hollowed-out parts, and the micro-needle patch 9 is embedded in the hollowed-out parts through a tenon.

[0048] It should be noted that the thigh section 1 and the calf section 3 are respectively provided with a hollowed-out structure. The hollowed-out shape is oval (major axis 10 mm, minor axis 6 mm), and the spacing is adjusted to 30-50 mm according to the acupoint distribution. The micro-needle patch 9 is embedded in the hollowed-out parts through a tenon. The tenon is made of polycarbonate material and is equipped with a spring lock device. When replacing the patch, press both sides to disassemble it. The edge of the hollowed-out part is covered with a silicone soft pad to prevent skin friction damage.

[0049] The micro-needle patch 9 covers acupoints including but not limited to Xuehai acupoint, Liangqiu acupoint, Dubi acupoint, Yanglingquan acupoint, and Zusanli acupoint.

[0050] It should be noted that the microneedle patch 9 covers Xuehai acupoint, Liangqiu acupoint, Dubi acupoint, Yanglingquan acupoint and Zusanli acupoint. The patch has a built-in micro positioning sensor (accuracy ±1mm), which is linked with the user terminal via Bluetooth, combined with the acupoint recognition algorithm of the APP (based on bone markers and body surface projection), to guide the user to accurately fit. The length of the microneedle is 0.3-0.5mm, and the needle tip is loaded with intelligent nano-drugs (such as drug-loaded liposomes or hydrogels). The drug release rate (0.1-1μL / min) is controlled by the piezoelectric drive module to achieve targeted drug delivery on demand;

[0051] In summary, the integrated monitoring kneepad device based on intelligent nano-new drugs disclosed in the present invention can integrate the angle sensor 7, the flexible patch temperature sensor 8 and the microneedle patch 9 through a cylindrical structure design. The angle sensor 7 collects the knee joint bending angle in real time and triggers an alarm when it exceeds the preset value. The flexible patch temperature sensor 8 is attached to the surface of the knee segment to continuously monitor local temperature changes and timely warn of inflammation or infection risks. The microneedle patch 9 is distributed in the thigh segment and the calf segment. With the help of the characteristics of microneedles penetrating the stratum corneum, the intelligent nano-drugs are directed to the acupuncture point area to improve the drug penetration efficiency.

[0052] Although the embodiments of the present invention have been shown and described above, it is to be understood that the above embodiments are exemplary and are not to be construed as limitations of the present invention. A person skilled in the art may change, modify, replace and vary the above embodiments within the scope of the present invention.

Claims

1. An integrated monitoring knee brace device based on a new type of intelligent nano drug, which is an axially extended cylindrical structure, and is divided into a thigh section (1), a knee section (2) and a calf section (3) along the axis of the lower limb of the human body, and the thigh section (1) and the calf section (3) are respectively provided with a strap (4), characterized in that: include: A thigh support (5), a calf support (6), an angle sensor (7), a flexible patch temperature sensor (8) and a plurality of microneedle patches (9), wherein the thigh support (5) is arranged on the thigh section (1), the calf support (6) is arranged on the calf section (3), one end of the thigh support (5) and one end of the calf support (6) intersect and are hinged at the knee section (2), the angle sensor (7) is arranged on the rotating shaft at the hinge, the flexible patch temperature sensor (8) is arranged on the knee section (2), and the microneedle patches (9) are respectively arranged on the thigh section (1) and the calf section (3).

2. The integrated monitoring knee brace device based on intelligent nano-new drugs as claimed in claim 1 is characterized in that: The inner wall of the thigh section (1) and the inner wall of the calf section (3) are respectively provided with annular silicone anti-slip patterns.

3. The integrated monitoring knee brace device based on intelligent nano-new drugs as claimed in claim 1 is characterized in that: The thigh support (5) and the thigh section (1) are connected by heat welding, and the calf support (6) and the calf section (3) are connected by heat welding.

4. The integrated monitoring knee brace device based on intelligent nano-new drugs as claimed in claim 1 is characterized in that: The thigh supporting member (5) and the calf supporting member (6) are L-shaped aluminum members respectively.

5. The integrated monitoring knee brace device based on intelligent nano-new drugs as claimed in claim 1, characterized in that: The thigh section (1) and the calf section (3) are respectively provided with hollows, and the microneedle patch (9) is embedded in the hollows by means of a tenon.

6. The integrated monitoring knee brace device based on intelligent nano-new drugs as claimed in claim 1, characterized in that: The microneedle patch (9) covers acupoints including but not limited to Xuehai acupoint, Liangqiu acupoint, Dubi acupoint, Yanglingquan acupoint and Zusanli acupoint.

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