Traditional Chinese medicine composition for treating skin hemangioma and preparation method thereof

Abstract

The invention relates to the technical field of traditional Chinese medicine preparations, and discloses a traditional Chinese medicine composition for treating skin hemangioma and a preparation method thereof. Comprising the following components in parts by mass: 15-25 parts of salvia miltiorrhiza, 10-20 parts of curcuma zedoary, 12-25 parts of selfheal, 10-15 parts of spina gleditsiae, 8-12 parts of purslane, 6-10 parts of verbena, 6-10 parts of honeycomb, 8-12 parts of wild buckwheat, 8-12 parts of indigo naturalis, 6-10 parts of philippine violet herb, 6-10 parts of lignum dalbergiae odoriferae, 4-8 parts of linseed, 8-12 parts of radix pseudostellariae, 4-8 parts of eclipta, 4-8 parts of black sedge, 4-8 parts of swertia mileensis and 6-8 parts of caulis spatholobi. Through reasonable compatibility of various traditional Chinese medicines, the traditional Chinese medicine composition comprehensively acts on skin hemangioma from the aspects of clearing away heat and toxic materials, promoting blood circulation to remove blood stasis, reducing swelling and removing stasis, reinforcing qi and nourishing blood and the like, can effectively improve symptoms of hemangioma and promote regression of tumor bodies, and is clinically verified to be high in effective rate.

Description

Technical Field

[0001] The present invention relates to the technical field of traditional Chinese medicine preparations, and in particular to a traditional Chinese medicine composition for treating skin hemangioma and a preparation method thereof. Background Art

[0002] Cutaneous hemangioma is a common disorder of abnormal vascular proliferation that occurs in infants and young children, particularly female infants. Its incidence rate is approximately 4%-5%, and has been increasing in recent years. Cutaneous hemangioma typically appears as red or purple patches on the skin surface, which not only affects appearance but can also lead to complications such as ulcers, bleeding, and infection, and in severe cases, can even affect organ function.

[0003] Currently, treatments for cutaneous hemangiomas primarily include surgical excision, laser therapy, cryotherapy, hormone therapy, and radiotherapy. However, these treatments have numerous drawbacks. Surgical excision may leave scars, impacting the patient's appearance and psychological well-being; laser therapy and cryotherapy may cause complications such as skin hyperpigmentation and scarring; hormone therapy may cause side effects such as endocrine disruption and immunosuppression; and radiotherapy carries the potential risk of carcinogenesis. Therefore, finding a safe, effective, and side-effect-free treatment is of great clinical significance.

[0004] Traditional Chinese medicine (TCM) has a long history and rich experience in treating skin diseases. In recent years, a growing number of studies have demonstrated the unique advantages of TCM preparations in treating cutaneous hemangiomas. These preparations can act through various pathways, such as regulating endothelial cell proliferation and apoptosis, inhibiting angiogenesis, and providing anti-inflammatory and antioxidant benefits, thereby achieving the goal of treating cutaneous hemangiomas. However, there are currently few TCM preparations available on the market for the treatment of cutaneous hemangiomas, and their efficacy varies widely.

[0005] Based on this, it is of great practical significance to provide a Chinese medicine composition for treating skin hemangioma with definite efficacy and low cost and a preparation method thereof. Summary of the Invention

[0006] In view of this, the present invention proposes a traditional Chinese medicine composition for treating skin hemangioma and a preparation method thereof, aiming to solve at least one of the above-mentioned background technical problems.

[0007] The present invention provides a traditional Chinese medicine composition for treating skin hemangioma, characterized by comprising the following components in parts by mass:

[0008] 15-25 parts of Salvia miltiorrhiza, 10-20 parts of Curcuma zedoaria, 12-25 parts of Prunella vulgaris, 10-15 parts of Spina Gleditsiae, 8-12 parts of Portulaca oleracea, 6-10 parts of Verbena, 6-10 parts of Honeycomb, 8-12 parts of Fagopyrum scabra, 8-12 parts of Indigo naturalis, 6-10 parts of Viola yedoensis, 6-10 parts of Dalbergia odorifera, 4-8 parts of Linseed, 8-12 parts of Pseudostellaria pseudoginseng, 4-8 parts of Ecliptae macrophylla, 4-8 parts of Herba Nigellae, 4-8 parts of Gallbladderwrack, and 6-8 parts of Millettia repens.

[0009] The present invention also provides a method for preparing the traditional Chinese medicine composition for treating skin hemangioma according to the above technical solution, comprising the following steps:

[0010] Weigh the raw materials according to the number of parts, including salvia miltiorrhiza, zedoaria, prunella vulgaris, honey locust thorn, purslane, verbena, honeycomb, golden buckwheat, indigo naturalis, viola yedoensis, dalbergia odorifera, linseed, pseudoginseng, eclipta prostrata, black seed grass, green leaf gall and millettia reticulata;

[0011] Washing the various components of the raw materials and then soaking them to obtain the standby medicinal materials;

[0012] The reserved medicinal materials are boiled over high heat, and then decocted over low heat for a first time, and then filtered for a first time to obtain a first filter residue and a first filter filtrate;

[0013] Adding water to the first filter residue for a second decoction, and then filtering to obtain a second filter residue and a second filter filtrate; the second decoction is specifically: first boiling over high heat, and then decocting over low heat for a second time;

[0014] The second filtered filtrate is mixed with the first filtered filtrate, and evaporated and concentrated to obtain the traditional Chinese medicine composition for treating skin hemangioma.

[0015] Preferably, the soaking is specifically: completely immersing the raw material components in water, wherein the total weight ratio of the raw material components to the water mass is 1:8-10, and the soaking is 30-60 minutes.

[0016] Preferably, the first decocting time on low heat is 30 to 60 minutes, the second decocting time on low heat is 20 to 40 minutes, and during the second decocting, the mass ratio of the first filter residue to water is 1:6 to 8.

[0017] Preferably, the temperature of the evaporation concentration is 60-80° C., and the time is 60-120 minutes.

[0018] The present invention also provides the use of the traditional Chinese medicine composition described in the above technical solution or the traditional Chinese medicine composition obtained by the preparation method in preparing a drug for treating skin hemangioma.

[0019] The present invention also provides a medicine for treating skin hemangioma, comprising the traditional Chinese medicine composition described in the above technical solution or the traditional Chinese medicine composition obtained by the above preparation method and a pharmaceutically acceptable carrier.

[0020] Preferably, the dosage form of the drug is decoction, pills, powder, capsule or ointment.

[0021] Compared with the prior art, the present invention has the following beneficial effects:

[0022] (1) Definite efficacy: The Chinese medicine composition of the present invention, through the rational combination of multiple Chinese medicines, has a comprehensive effect on skin hemangiomas from multiple aspects such as clearing away heat and detoxifying, promoting blood circulation and removing blood stasis, reducing swelling and dispersing nodules, and invigorating qi and nourishing blood. It can effectively improve the symptoms of hemangiomas and promote the regression of tumors. Clinical verification shows that the efficacy is high.

[0023] (2) No toxic side effects: Using natural Chinese medicine as raw materials, it avoids the toxic side effects that may be caused by chemical drugs. It is safe and harmless to the human body and is especially suitable for younger or weaker patients.

[0024] (3) Less prone to recurrence: By regulating the overall function of the human body, enhancing the body's resistance, improving local blood circulation and tissue conditions, it can fundamentally treat skin hemangiomas and reduce the possibility of recurrence.

[0025] (4) Simple preparation method: The preparation method of the present invention is simple to operate, does not require complicated equipment and technology, and is easy to realize industrial production. DETAILED DESCRIPTION

[0026] Various exemplary embodiments of the present invention are now described in detail. This detailed description should not be considered as a limitation of the present invention, but should be understood as a more detailed description of certain aspects, features, and embodiments of the present invention. It should be understood that the terms used in the present invention are only for describing specific embodiments and are not intended to limit the present invention.

[0027] In addition, for numerical ranges in the present invention, it is understood that each intervening value between the upper and lower limits of the range is also specifically disclosed. Each smaller range between any stated value or intervening value in a stated range and any other stated value or intervening value in the stated range is also included in the present invention. The upper and lower limits of these smaller ranges may independently be included or excluded in the range.

[0028] Unless otherwise indicated, all technical and scientific terms used herein have the same meaning as commonly understood by those skilled in the art. Although only preferred methods and materials are described herein, any methods and materials similar or equivalent to those described herein may also be used in the practice or testing of the present invention. All documents mentioned in this specification are incorporated by reference to disclose and describe the methods and / or materials associated with the documents. In the event of any conflict with any incorporated document, the contents of this specification shall prevail.

[0029] It will be apparent to those skilled in the art that various modifications and variations may be made to the specific embodiments described herein without departing from the scope or spirit of the invention. Other embodiments will be apparent to those skilled in the art from the description of the invention. The description and examples are intended to be exemplary only.

[0030] The words “include,” “including,” “have,” “contain,” etc. used in this document are open-ended terms, meaning including but not limited to.

[0031] The present invention provides a traditional Chinese medicine composition for treating skin hemangioma, comprising the following components in parts by weight:

[0032] 15-25 parts of Salvia miltiorrhiza, 10-20 parts of Curcuma zedoaria, 12-25 parts of Prunella vulgaris, 10-15 parts of Spina Gleditsiae, 8-12 parts of Portulaca oleracea, 6-10 parts of Verbena, 6-10 parts of Honeycomb, 8-12 parts of Fagopyrum scabra, 8-12 parts of Indigo naturalis, 6-10 parts of Viola yedoensis, 6-10 parts of Dalbergia odorifera, 4-8 parts of Linseed, 8-12 parts of Pseudostellaria pseudoginseng, 4-8 parts of Ecliptae macrophylla, 4-8 parts of Herba Nigellae, 4-8 parts of Gallbladderwrack, and 6-8 parts of Millettia repens.

[0033] The components in parts by mass are preferably: 15-20 parts of Salvia miltiorrhiza, 10-15 parts of Curcuma zedoaria, 12-20 parts of Prunella vulgaris, 10-12 parts of Gleditsia chinensis, 8-10 parts of Portulaca oleracea, 6-8 parts of Verbena officinalis, 6-8 parts of Honeycomb, 8-10 parts of Fagopyrum scabra, 8-10 parts of Indigo naturalis, 6-8 parts of Viola yedoensis, 6-8 parts of Dalbergia odorifera, 4-6 parts of linseed, 8-10 parts of Pseudostellaria pseudoginseng, 4-6 parts of Eclipta prostrata, 4-6 parts of Nigella nigra, 4-6 parts of Gallbladderwrack, and 6-7 parts of Millettia reticulata.

[0034] The components added in the present invention have different effects on the treatment of skin hemangiomas. Salvia miltiorrhiza, Curcuma zedoaria, Verbena officinalis, Dalbergia odorifera, and Millettia reticulata have the effect of promoting blood circulation and removing blood stasis, targeting the core symptom of hemangioma "blood stasis"; Prunella vulgaris, Gleditsia thorn, and Beehive can disperse nodules and reduce swelling; Portulaca oleracea, Fagopyrum scabra, Indigo naturalis, and Viola yedoensis can clear away heat and detoxify; Pseudostellaria pseudoginseng and Millettia reticulata can invigorate qi and nourish blood, etc. Specifically:

[0035] Danshen: It has the effects of promoting blood circulation, removing blood stasis, relieving pain, clearing the heart and eliminating restlessness, and cooling blood and eliminating carbuncle. For skin hemangiomas, its blood circulation-activating and blood stasis-eliminating effects can effectively improve local blood circulation, dissipate blood stasis, and alleviate symptoms such as swelling at the hemangioma site caused by blood stasis. Components such as tanshinone contained in Danshen inhibit platelet aggregation and dilate blood vessels, increasing local blood perfusion in the hemangioma and promoting the repair of diseased tissue. Furthermore, Danshen's blood-cooling and carbuncle-eliminating effects can reduce inflammation in the tissue surrounding the hemangioma, preventing further progression of the disease.

[0036] Curcuma zedoaria: It has the effects of promoting qi and dispersing blood, dissipating stagnation, and relieving pain. In the treatment of skin hemangiomas, its qi-promoting and blood-dispersing effects can effectively dissipate blood stasis, providing a targeted therapeutic effect on hemangiomas caused by qi stagnation and blood stasis, and can promote tumor reduction. Curcuma zedoaria, including its components such as curcuma oil, has anti-tumor and anti-inflammatory effects, inhibiting the abnormal proliferation of hemangioma endothelial cells, thereby controlling tumor growth. Furthermore, its analgesic and relieving effects can alleviate pain and discomfort caused by hemangioma pressure on surrounding tissues.

[0037] Prunella Vulgaris: It has the effects of clearing the liver and purging heat, improving eyesight, and dispersing swelling. By clearing the liver and purging heat, it regulates the internal heat and heat, and has a therapeutic effect on skin hemangiomas caused by accumulated heat and toxins. Prunella Vulgaris's dispersing and relieving swelling is particularly important, helping to dissipate the mass of hemangiomas and promote their regression.

[0038] Gleditsia thorns: They have the effects of reducing swelling, expelling toxins, draining pus, and killing insects. In the present invention, they can help dissipate localized swelling in hemangiomas, promote the rupture and drainage of carbuncles, and play an important role in improving the localized stagnation of qi and blood in hemangiomas. Modern research shows that the various chemical components contained in Gleditsia thorns have antibacterial and anti-inflammatory effects, effectively alleviating inflammatory reactions in the tissues surrounding hemangiomas.

[0039] Purslane: It has the effects of clearing heat and detoxifying, cooling blood and stopping bleeding, and relieving dysentery. Its cold nature can eliminate heat and toxins from the body, making it a targeted treatment for skin hemangiomas caused by accumulated heat and toxins. Furthermore, purslane is rich in vitamin A-like substances, which can promote the normal physiological function of epithelial cells and aid in the repair of damaged skin tissue.

[0040] Verbena: It promotes blood circulation, dissipates blood stasis, detoxifies, promotes diuresis, reduces jaundice, and treats malaria. In the treatment of skin hemangiomas, verbena can promote blood circulation, dissipate blood stasis, and improve blood stasis at the site of the hemangioma, thereby alleviating hemangioma symptoms. Components such as verbenain in it have anti-inflammatory and analgesic properties, alleviating local pain and discomfort caused by hemangiomas.

[0041] Beehive: It can attack toxins and kill insects, dispel wind and relieve pain. For skin hemangiomas, beehive can exert its anti-toxin effect, helping to dissipate the tumor. Its anti-wind and pain-relieving properties can also alleviate pain caused by the hemangioma's growth compressing surrounding tissues. The various active ingredients in beehive have antibacterial, antiviral, and anti-inflammatory properties, helping to strengthen the body's immune system and promote recovery.

[0042] Golden buckwheat: It has the effects of clearing heat and detoxifying, discharging pus and removing blood stasis. In the treatment of skin hemangiomas, golden buckwheat can clear heat and toxins from the body, expelling pus and blood stasis caused by qi and blood stasis, thereby improving the local pathological state of the hemangioma. Modern pharmacological research has found that golden buckwheat has anti-tumor, anti-inflammatory, and immune-enhancing effects, and plays a positive auxiliary role in the treatment of skin hemangiomas.

[0043] Indigo: It clears heat and detoxifies, cools blood, eliminates freckles, and relieves heat and calms nerves. Its cold nature makes it effective in clearing heat and toxins from the body, alleviating local symptoms such as redness, swelling, heat, and pain. Indigo and other ingredients in Indigo have anti-inflammatory, antibacterial, antiviral, and anti-tumor properties, inhibiting the proliferation of hemangioma endothelial cells, thereby achieving its therapeutic purpose.

[0044] Viola yedoensis: It clears heat and detoxifies, cools blood, and reduces swelling. In this application, Viola yedoensis primarily targets localized heat and blood stasis in skin hemangiomas, improving their symptoms by clearing heat and detoxifying, cooling blood, and reducing swelling. Its rich flavonoids and other ingredients have antibacterial, anti-inflammatory, and antioxidant properties, helping to alleviate inflammatory responses and promote local tissue repair.

[0045] Dalbergia odorifera: It has the effects of dissolving blood stasis, stopping bleeding, regulating qi, and relieving pain. In the treatment of skin hemangiomas, Dalbergia odorifera can promote the dissipation of blood stasis at the site of the hemangioma, improve blood circulation, and alleviate pain caused by blood stasis. Its volatile oils and other components have antiplatelet aggregation and vasodilatory effects, improving local blood supply and promoting improvement.

[0046] Flaxseed: Moisturizes and dispels wind. In the present invention's formula, flaxseed can improve dry skin and help restore normal skin function. Its rich unsaturated fatty acids and other ingredients nourish the skin, complementing other medications to promote skin tissue repair and mitigate skin damage caused by hemangiomas and treatment.

[0047] Pseudostellariae Radix: It has the benefits of invigorating Qi and strengthening the spleen, promoting fluid production and moistening the lungs. When used to treat skin hemangiomas, Pseudostellariae Radix can replenish the body's vital Qi, enhance the body's resistance, and help the body better cope with illness. Furthermore, its ability to promote fluid production and moisten the lungs can improve fluid depletion caused by long-term illness or medication, contributing to the recovery of overall bodily functions.

[0048] Eclipta prostrata nourishes the liver and kidneys, cools blood, and stops bleeding. For patients with skin hemangiomas, Eclipta prostrata nourishes the liver and kidneys, regulates the body's yin and yang balance, and enhances immunity. Its cooling and hemostatic properties can prevent and treat bleeding symptoms caused by hemangioma rupture. Eclipta prostrata contains various chemical components with antioxidant, anti-inflammatory, and immunomodulatory properties, demonstrating its potential in treating skin hemangiomas.

[0049] Black Seed Grass: It has kidney-tonifying and brain-strengthening properties, promotes menstruation, promotes lactation, and acts as a diuretic. In this invention, black seed grass can help regulate the body's endocrine and metabolic functions, promoting overall health. Its effects on menstruation and other functions help improve blood circulation and have a certain auxiliary effect in the treatment of skin hemangiomas. Modern research shows that black seed grass contains multiple active ingredients with anti-inflammatory, antibacterial, and immune-regulating effects.

[0050] Green Leaf Gallbladder: It has the effects of clearing the liver and promoting bile secretion, clearing heat and removing dampness. For patients with skin hemangiomas, Green Leaf Gallbladder can regulate the liver's function of dispersing qi, improve the body's qi flow, and promote blood circulation. Its heat-clearing and dampness-removing effects can eliminate dampness and heat in the body, helping to improve skin pathologies. The various chemical components in Green Leaf Gallbladder have hepatoprotective, bile-stimulating, and anti-inflammatory properties, making them a helpful aid in the treatment of skin hemangiomas.

[0051] Millettia reticulata: It promotes blood circulation, replenishes blood, regulates menstruation and relieves pain, and relaxes tendons and activates blood vessels. In the treatment of skin hemangiomas, Millettia reticulata can promote blood circulation, dissipate blood stasis, and replenish blood, improving local blood supply deficiency caused by blood stasis. Its relaxing and activating effects can alleviate numbness, pain, and other discomfort caused by hemangioma growth compressing surrounding tissues. The various chemical components in Millettia reticulata have antiplatelet aggregation, vasodilatory, and anti-inflammatory properties, playing a significant role in the treatment of skin hemangiomas.

[0052] The present invention also provides a method for preparing the traditional Chinese medicine composition for treating skin hemangioma according to the above technical solution, comprising the following steps:

[0053] Weigh the raw materials according to the number of parts, including salvia miltiorrhiza, zedoaria, prunella vulgaris, honey locust thorn, purslane, verbena, honeycomb, golden buckwheat, indigo naturalis, viola yedoensis, dalbergia odorifera, linseed, pseudoginseng, eclipta prostrata, black seed grass, green leaf gall and millettia reticulata;

[0054] Washing the various components of the raw materials and then soaking them to obtain the standby medicinal materials;

[0055] The reserved medicinal materials are boiled over high heat, and then decocted over low heat for a first time, and then filtered for a first time to obtain a first filter residue and a first filter filtrate;

[0056] Adding water to the first filter residue for a second decoction, and then filtering to obtain a second filter residue and a second filter filtrate; the second decoction is specifically: first boiling over high heat, and then decocting over low heat for a second time;

[0057] The second filtered filtrate is mixed with the first filtered filtrate, and evaporated and concentrated to obtain the traditional Chinese medicine composition for treating skin hemangioma.

[0058] In the present invention, the soaking is preferably: completely immersing the raw material components in water, wherein the total weight ratio of the raw material components to the water mass is preferably 1:8-10, and the soaking is preferably 30-60 minutes.

[0059] In the present invention, the first low-heat decocting time is preferably 30 to 60 minutes, the second low-heat decocting time is preferably 20 to 40 minutes, and during the second decocting, the mass ratio of the first filter residue to water is preferably 1:6 to 8.

[0060] In the present invention, the temperature of the evaporation concentration is preferably 60 to 80° C., and the time is preferably 60 to 120 minutes.

[0061] The present invention also provides the use of the traditional Chinese medicine composition described in the above technical solution in preparing a medicine for treating skin hemangioma.

[0062] The present invention also provides a medicine for treating skin hemangioma, comprising the traditional Chinese medicine composition described in the above technical solution or the traditional Chinese medicine composition obtained by the above preparation method and a pharmaceutically acceptable carrier.

[0063] In the present invention, the dosage form of the medicine is decoction, pill, powder, capsule or paste.

[0064] Example 1

[0065] (1) Weigh the following raw materials: 15 parts of Salvia miltiorrhiza, 10 parts of Curcuma zedoaria, 12 parts of Prunella vulgaris, 10 parts of Gleditsia sinensis, 8 parts of Portulaca oleracea, 6 parts of Verbena officinalis, 6 parts of Honeycomb, 8 parts of Fagopyrum scabra, 8 parts of Indigo naturalis, 6 parts of Viola yedoensis, 6 parts of Dalbergia odorifera, 4 parts of Linseed, 8 parts of Pseudostellaria baicalensis, 4 parts of Eclipta prostrata, 4 parts of Nigella nigra, 4 parts of Gallbladderwort, and 6 parts of Millettia repens.

[0066] (2) Weigh each raw material as described above, wash it, add 8 times the total weight of water, and soak for 30 minutes;

[0067] (3) boiling the mixture after soaking, then boiling it over high heat and then decocting it over low heat for 30 minutes, and filtering to obtain a first filtrate and a first filter residue;

[0068] (4) adding 6 times the weight of the filter residue to the first filter residue, boiling over high heat, then simmering over low heat for 20 minutes, and filtering to obtain a second filtrate;

[0069] (5) The two filtrates were combined and concentrated by evaporation at 60°C for 60 minutes to obtain a Chinese medicine composition.

[0070] Example 2

[0071] (1) Weigh the following raw materials: 20 parts of Salvia miltiorrhiza, 15 parts of Curcuma zedoaria, 20 parts of Prunella vulgaris, 12 parts of Gleditsia sinensis, 10 parts of Portulaca oleracea, 8 parts of Verbena officinalis, 8 parts of Honeycomb, 10 parts of Fagopyrum scabra, 10 parts of Indigo naturalis, 8 parts of Viola yedoensis, 8 parts of Dalbergia odorifera, 6 parts of Linseed, 10 parts of Pseudostellaria baicalensis, 6 parts of Eclipta prostrata, 6 parts of Nigella nigra, 6 parts of Gallbladderwrack, and 7 parts of Millettia repens.

[0072] (2) Weigh each raw material as described above, wash it, add 9 times the total weight of water, and soak for 45 minutes;

[0073] (3) boiling the mixture after soaking, then boiling it over high heat and then decocting it over low heat for 45 minutes, and filtering to obtain a first filtrate and a first filter residue;

[0074] (4) adding 7 times the weight of the first filter residue to the filter residue, boiling over high heat, then simmering over low heat for 30 minutes, and filtering to obtain the second filtrate;

[0075] (5) The filtrates were combined and concentrated by evaporation at 70° C. for 90 minutes to obtain a Chinese medicine composition.

[0076] Example 3

[0077] (1) Weigh the following raw materials: 25 parts of Salvia miltiorrhiza, 20 parts of Curcuma zedoaria, 25 parts of Prunella vulgaris, 15 parts of Gleditsia sinensis, 12 parts of Portulaca oleracea, 10 parts of Verbena officinalis, 10 parts of Honeycomb, 12 parts of Fagopyrum scabra, 12 parts of Indigo naturalis, 10 parts of Viola yedoensis, 10 parts of Dalbergia odorifera, 8 parts of Linseed, 12 parts of Pseudostellaria baicalensis, 8 parts of Eclipta prostrata, 8 parts of Nigella nigra, 8 parts of Gallbladderwrack, and 8 parts of Millettia repens.

[0078] (2) Weigh each raw material as described above, wash it, add 10 times the total weight of water, and soak for 60 minutes;

[0079] (3) boiling the mixture after soaking, then boiling it over high heat and then decocting it over low heat for 60 minutes, and filtering to obtain a first filtrate and a first filter residue;

[0080] (4) adding 8 times the weight of the first filter residue into the water, boiling over high heat, then simmering over low heat for 40 minutes, and filtering to obtain the second filtrate;

[0081] (5) The filtrates were combined and concentrated by evaporation at 80° C. for 120 minutes to obtain a Chinese medicine composition.

[0082] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention and not to limit it. Although the present invention has been described in detail with reference to the above embodiments, ordinary technicians in the field should understand that the specific implementation methods of the present invention can still be modified or replaced by equivalents. Any modification or equivalent replacement that does not depart from the spirit and scope of the present invention should be covered by the scope of protection of the claims of the present invention.

Claims

1. A Chinese medicine composition for treating skin hemangioma, characterized in that: The composition includes the following parts by weight: 15-25 parts of Salvia miltiorrhiza, 10-20 parts of Curcuma zedoaria, 12-25 parts of Prunella vulgaris, 10-15 parts of Spina Gleditsiae, 8-12 parts of Portulaca oleracea, 6-10 parts of Verbena, 6-10 parts of Honeycomb, 8-12 parts of Fagopyrum scabra, 8-12 parts of Indigo naturalis, 6-10 parts of Viola yedoensis, 6-10 parts of Dalbergia odorifera, 4-8 parts of Linseed, 8-12 parts of Pseudostellaria pseudoginseng, 4-8 parts of Ecliptae macrophylla, 4-8 parts of Herba Nigellae, 4-8 parts of Gallbladderwrack, and 6-8 parts of Millettia repens.

2. A method for preparing the Chinese medicine composition for treating skin hemangioma according to claim 1, characterized in that: The following steps are involved: Weigh the raw materials according to the number of parts, including salvia miltiorrhiza, zedoaria, prunella vulgaris, honey locust thorn, purslane, verbena, honeycomb, golden buckwheat, indigo naturalis, viola yedoensis, dalbergia odorifera, linseed, pseudoginseng, eclipta prostrata, black seed grass, green leaf gall and millettia reticulata; Washing the various components of the raw materials and then soaking them to obtain the standby medicinal materials; The reserved medicinal materials are boiled over high heat, and then decocted over low heat for a first time, and then filtered for a first time to obtain a first filter residue and a first filter filtrate; Adding water to the first filter residue for a second decoction, and then filtering to obtain a second filter residue and a second filter filtrate; the second decoction is specifically: first boiling over high heat, and then decocting over low heat for a second time; The second filtered filtrate is mixed with the first filtered filtrate, and evaporated and concentrated to obtain the traditional Chinese medicine composition for treating skin hemangioma.

3. The method for preparing the Chinese medicine composition for treating skin hemangioma according to claim 2, wherein: The soaking specifically comprises: completely immersing the raw material components in water, wherein the total weight ratio of the raw material components to the water mass is 1:8-10, and the soaking is for 30-60 minutes.

4. The method for preparing the Chinese medicine composition for treating skin hemangioma according to claim 2, wherein: The first low-heat decocting time is 30 to 60 minutes, the second low-heat decocting time is 20 to 40 minutes, and during the second decocting, the mass ratio of the first filter residue to water is 1:6 to 8.

5. The method for preparing the Chinese medicine composition for treating skin hemangioma according to claim 2, wherein: The temperature of the evaporation concentration is 60-80° C., and the time is 60-120 minutes.

6. Use of the Chinese medicine composition according to claim 1 or the Chinese medicine composition obtained by the preparation method according to claim 2 in preparing a drug for treating skin hemangioma.

7. A drug for treating skin hemangioma, characterized in that: The invention comprises the traditional Chinese medicine composition according to claim 1 or the traditional Chinese medicine composition obtained by the preparation method according to claim 2 and a pharmaceutically acceptable carrier.

8. The drug for treating skin hemangioma according to claim 7, characterized in that: The dosage form of the medicine is decoction, pill, powder, capsule or ointment.