Ophthalmic lens with extended depth of focus for improving intermediate vision

Abstract

The invention relates to an ophthalmic lens with extended depth of focus for improving intermediate vision. The present disclosure provides an ophthalmic lens, such as an IOL, designed to enhance the depth of focus of intermediate vision performance while maintaining distant vision. The lens may include an optical device having an optical axis and a composite multilayer surface profile corresponding to a superposition of at least three profiles, the three profiles including: a base structure; a phase shift structure; and a regional structure having an inner power region and an outer transition region. The phase shift structure may have an inner region, an outer region, and a transition region.

Description

[0001] This application is a divisional application of the application filed on April 15, 2021, with application number 202180028264.6 and invention title "Ophthalmic Lens with Extended Depth of Focal Length for Improving Intermediate Vision".

[0002] Priority Statement

[0003] This application claims the benefit of U.S. Provisional Patent Application Serial No. 63 / 010,792, filed April 16, 2020, entitled “OPHTHALMIC LENSES HAVING AN EXTENDEDDEPTH OF FOCUS FOR IMPROVING INTERMEDIATE VISION”, inventors Myoung-Taek Choi, Sangyeol Lee, Shinwook Lee, and William Lee, the entire contents of which are hereby incorporated herein by reference, as if fully and completely set forth herein. Technical Field

[0004] This disclosure generally pertains to the field of ophthalmic lenses, and more specifically to lenses having an extended depth of focus for improving intermediate vision. Background Technology

[0005] Ophthalmic lenses (such as intraocular lenses) are routinely implanted into a patient's eye during cataract surgery to replace the natural lens. The optical power of the natural lens can be varied under the influence of the ciliary muscle, thus providing accommodation to see objects at different distances from the eye. Many intraocular lenses provide improved distance vision performance, but may not provide extended depth of focus for intermediate vision. Summary of the Invention

[0006] This disclosure generally relates to an ophthalmic lens (such as an IOL) that enhances the depth of focus for intermediate vision while maintaining distance vision.

[0007] According to this disclosure, the lens includes an optical element having a front surface and a rear surface disposed around an optical axis, at least one of the front and rear surfaces having a superimposed surface profile corresponding to at least three profiles. These three profiles include a phase-shifting structure, a regional structure, and a base structure or curvature. The phase-shifting structure is characterized by an inner region, an outer region, and a transition region. The inner region extends radially from the optical axis to a first boundary. The transition region is disposed between the inner region and the outer region and extends radially from the first boundary to a second boundary, wherein the transition region is adapted such that the phase of radiation incident thereon changes linearly over at least a portion of a radial range between the first and second boundaries to produce a phase shift between the first and second boundaries. The second boundary is disposed at a radial distance further away from the optical axis than the first boundary. The outer region extends radially from the second boundary toward the outermost edge of the optical element. The regional structure includes an inner focal region having a first curvature and an outer transition region having a second curvature. The inner focal region extends radially from the optical axis to the second boundary, and the outer transition region extends radially to a third boundary. The third boundary is located at a radial distance further away from the optical axis than the second boundary. The fundamental curvature extends radially from the third boundary to the outermost edge of the optics. Attached Figure Description

[0008] Figure 1A A top view of an example embodiment of an ophthalmic lens according to this disclosure is shown;

[0009] Figure 1B A side view of an example embodiment of an ophthalmic lens according to this disclosure is shown;

[0010] Figure 2 An exploded cross-sectional view of the layers and composite height loss of an example optical device according to this disclosure is shown;

[0011] Figure 3A A graph showing the surface drop of the phase-shifting structure of an example optical device according to this disclosure versus its radial distance from the optical axis is presented.

[0012] Figure 3B A graph showing the surface drop of a region structure relative to the radial distance from the optical axis for an example optical device according to this disclosure is presented.

[0013] Figure 3C A graph showing the composite surface drop versus radial distance from the optical axis for an example optical device according to this disclosure is presented.

[0014] Figure 4A A defocus modulation transfer function (MTF) curve of a conventional monofocus IOL according to this disclosure is shown;

[0015] Figure 4BThe defocus MTF curve of an optical device with only a phase-shifting structure according to this disclosure is shown;

[0016] Figure 4C The defocus MTF curve of an optical device with only a regional focal structure according to this disclosure is shown;

[0017] Figure 4D The defocus MTF curve of the example optics according to this disclosure is shown; and

[0018] Figure 5 A graph showing visual acuity (VA) versus defocus according to this disclosure is presented, and the depth of focus extension of an example optics is depicted.

[0019] As will be understood by those skilled in the art, the accompanying drawings described below are for illustrative purposes only and are not intended to limit the scope of this disclosure. Detailed Implementation

[0020] Intraocular lenses (IOLs) are the most common type of lens used in cataract surgery. A monofocal IOL is an intraocular lens with a single focal point at a single distance, such as near, intermediate, or far vision. Because monofocal IOLs can only be set for one distance, and because most patients and practitioners choose far vision, patients may need additional eyewear to correct near and / or intermediate vision. Additionally, depth of focus decreases with age. Depth of focus (measured in diopters (D)) is the total distance in front of and behind a focal point at which an image can be focused without a loss of sharpness exceeding a certain permissible amount. Traditional monofocal IOLs are limited in their ability to extend depth of focus.

[0021] This disclosure generally relates to an ophthalmic lens (such as a monofocal IOL) whose surface profile improves intermediate vision while maintaining image quality for distance vision and further extends the depth of focus. Although the following disclosure is described in conjunction with an IOL, it should be understood that the features and elements of this disclosure are not limited to any particular type of IOL and can be applied to monofocal or multifocal IOLs. Furthermore, this disclosure can be further applied to non-IOL ophthalmic lenses, such as contact lenses. Additionally, as used herein, the term "intraocular lens" (and its abbreviation IOL) is used to describe a lens implanted inside the eye to replace the eye's natural lens or otherwise enhance vision, regardless of whether the natural lens is removed.

[0022] Now for reference Figure 1A and Figure 1B The present disclosure depicts an example embodiment of an intraocular lens 100 according to this disclosure. Figure 1A A top view of the front surface 130 of the lens 100 is depicted, and Figure 1BA side view illustrating the front surface 130 and rear surface 140 of lens 100 is depicted. Lens 100 may include a plurality of loops 110 generally operable to position and stabilize lens 100 within the capsular bag of a patient's eye. Lens 100 may further include an optics 120 having a front surface 130 and a rear surface 140 disposed around the optical axis 105 of the lens. Figure 1A and Figure 1B As shown, the optical axis 105 passes through the geometric center of the optical device 120. One of the front surface 130 and the rear surface 140 may include an aspherical or spherical surface profile, while the other surface may include a multi-layered surface profile formed by the superposition of three profiles or structures. For illustrative purposes, the multi-layered surface profile is depicted on... Figure 1A On the front surface 130 of the optical device 120. However, it should be understood that, in combination Figure 1A The multi-layer surface profile shown and described may alternatively be applied to the rear surface 140 of the optics 120, and the aspherical or spherical surface profile may be applied to the front surface 130 of the optics 120.

[0023] Now combine Figure 2 For reference Figure 1A . Figure 2 An exploded cross-sectional view is shown, illustrating the individual layers or structures 150, 160, 170 that form the multilayer surface profile of the front surface 130 of the optical device 120, and the composite or synthetic height 180 of the front surface 130 of the optical device 120. Figure 1A A top view (top view) shows the profile of the composite multilayer surface of the front surface 130 of the optical device 120, in which... Figure 1A The radial boundaries 122, 124, 126, and 128 in the diagram correspond to... Figure 2 The boundaries of the medium structure are 150, 160, and 170. Figure 2 It should be understood that the left and right sides of the optical axis 105 are mirror images of each other. Therefore, the structures, boundaries, and names shown on a given side of the optical axis 105 can be equally applied to the other side of the optical axis 105.

[0024] The multi-layer surface profile of the front surface 130 may include a superposition of at least three profiles or structures: a phase-shifting structure 150; an aspherical region structure 160; and an aspherical base structure 170. The region structure 160 may further include a superposition of an inner focal region 162 and an outer transition region 164. As described above, each of these structures may be defined by combining multiple radial boundaries 122, 124, 126, 128, which are formed at an increased radial distance from the optical axis 105 of the optics device 120. The multi-layer surface profile (Z) of the front surface 130 of the optics device 120 total(Including phase shift structure 150, region structure 160, and basic structure 170) can be defined by the following equation:

[0025] Equation (1) Z total = Z aux + Z zone1 + Z zone2 + Z base ,

[0026] in,

[0027] Z aux The surface profile of phase-shifting structure 150 is shown.

[0028] Z zone1 The surface profile of the internal focal zone 162 of the region structure 160;

[0029] Z zone2 The surface profile of the outer transition region 164 of the region structure 160; and Z base This represents the surface profile of the basic structure 170.

[0030] Each of these structures 150, 160, and 170 will be described in turn.

[0031] First, the phase-shifting structure 150 may include a trapezoidal phase-shift (TPS) feature having an inner region 152, a transition region 154, and an outer region 156. The inner region 152 extends radially from the optical axis 150 to a first radial boundary 122. The transition region 154 extends radially from the first radial boundary 122 to a second radial boundary 124, which is located at a radial distance further from the optical axis 105 than the first radial boundary 122. The transition region 154 may be configured such that the phase of the radiation incident thereon changes linearly over at least a portion of the radial range between the first radial boundary 122 and the second radial boundary 124, to produce a phase shift between the first radial boundary 122 and the second radial boundary 124. The outer region 156 of the phase-shifting structure 150 extends radially from the second radial boundary 124 to the outermost edge 128 of the optics 120.

[0032] Figure 2 The trapezoidal phase shift structure 150 shown can be defined by the following equation:

[0033] Equation (2a)

[0034] in,

[0035] r represents the radial distance from the optical axis 105 of the optical device 120.

[0036] r1 represents the radial distance from the optical axis 105 to the first radial boundary 122;

[0037] r2 represents the radial distance from the optical axis 105 to the second radial boundary 124; and

[0038] Δ represents the step height of phase shift structure 150 relative to internal region 152;

[0039] And among them,

[0040] Δ is defined by the following relationship:

[0041] Equation (2b)

[0042] in,

[0043] n1 represents the refractive index of the material forming the optical device.

[0044] n2 represents the refractive index of the medium surrounding the optical device.

[0045] λ represents the design wavelength, and

[0046] α represents a non-integer decimal.

[0047] In the embodiment, the phase shift structure 150, as defined by equations (2a) and (2b), is characterized by a substantially linear phase shift over the transition region 154. More specifically, the phase shift structure 150 provides a phase shift that increases linearly from the inner boundary of the transition region 154 (corresponding to the first radial boundary 122) to the outer boundary of the transition region 154 (corresponding to the second radial boundary 124), wherein the optical path difference between the inner and outer boundaries (or between the first and second radial boundaries 122, 124) corresponds to a non-integer fraction of the design wavelength.

[0048] In operation, the trapezoidal phase-shift structure 150 can generate continuous focal shifts by means of the forward wavefront delay between the inner region 152 and the outer region 156, which causes a collective depth of focus extension. The phase-shift structure can generate varying amounts of phase shifts in light waves passing through the optics 120 (depending on the region of the optics 120 through which the light waves pass), and structural interference between light waves with different amounts of phase shifts can produce an extended depth of focus. As described below, additional depth of focus extension can be achieved by adding an inner focal power region 162 of the region structure 160 to the phase-shift structure 150. In this case, the phase-shift structure 150 can help mitigate undesirable pupil-related focal shifts that may be caused by the enhanced depth of focus extension resulting from the inner focal power region 162. Furthermore, without the trapezoidal phase-shift structure 150, the optics 120 will essentially function as a bifocal design.

[0049] In one embodiment, the radial distance r1 of the inner region 152 of the phase shift structure 150 (from the optical axis 105 to the first radial boundary 122) can include a value ranging from approximately 0.45 mm to 0.75 mm. The radial distance r2 from the optical axis 105 to the second radial boundary 124 can include a value ranging from approximately 0.75 mm to 1.05 mm. Additionally, the step height Δ of the phase shift structure 150 can be approximately -2.1 μm.

[0050] Continue to combine Figure 2 For reference Figure 1A The region structure 160 may include an inner focal length region 162 and an outer transition region 164. The inner focal length region 162 may have a first curvature and may extend radially from the optical axis 105 to a second radial boundary 124, and as shown... Figure 2 As shown, the inner region and transition regions 152, 154 of the phase-shifting structure 150 can overlap. The inner focal power region 162 may include a refractive surface and may be configured to enhance the depth of focus for improving intermediate vision performance. Specifically, while the trapezoidal phase-shifting structure 150 itself may have the ability to improve the depth of focus and visual acuity of intermediate vision, the inner focal power region 162 (with additional refractive power higher than the base structure 170) can produce an additional focal power effect, which, when combined with the phase-shifting structure 150, can further increase the depth of focus and improve intermediate vision. Furthermore, the combination of the trapezoidal phase-shifting structure 150 and the inner focal power region 162 allows the optics to flexibly perform intermediate vision control in terms of both focal length and focal power. In an embodiment, the inner focal power region 162 is located in the innermost region of the optics 120. This positioning is particularly important for extending the depth of focus upwards and improving visual acuity. In an embodiment, the additional focal power range in the inner focal power region 162 may be from 0.7D to 2.4D. In an embodiment, for pupil diameters from 2 mm to 6 mm, the internal focal zone 162 can extend the depth of focus to up to 2.38D and improve visual acuity by 0.2.

[0051] In an embodiment, Figure 2 The internal focal length region 162 shown can be defined by the following equation:

[0052] Equation (3)

[0053] in,

[0054] r represents the radial distance from the optical axis 105 of the optical device 120.

[0055] c1 represents the basic curvature of the internal focal length region 162.

[0056] k1 represents the conic constant.

[0057] r2 represents the radial distance from the optical axis 105 to the second radial boundary 124.

[0058] A4' is the fourth-order aspherical coefficient, and

[0059] A6' is the sixth-order aspherical coefficient.

[0060] In embodiments, r2 can include values ​​ranging from approximately 0.45 mm to 0.80 mm. In one embodiment, the value of r2 in equation (3) of the internal focal region 162 can be substantially equal to the value of r2 in equation (2a) of the trapezoidal phase shift structure 150. In yet another embodiment, there may be some degree of variation between the value of r2 in equation (3) of the internal focal region 162 and the value of r2 in equation (2a) of the trapezoidal phase shift structure 150. Therefore, in some embodiments, the position of the second radial boundary 124 can be understood as a reference point, which can vary or differ relative to various structures such as the phase shift structure 150 and the region structure 160 of the optics 120. The fundamental curvature c1 of the internal focal region 162 can include values ​​ranging from approximately 19.0 mm. -1 up to 20.2mm -1 The value is used for, for example, the intermediate diopter value of 21D. The value of the conic constant k1 can range from approximately -100 to -30. The fourth-order aspheric coefficient A4' can include values ​​ranging from approximately -6.5 × 10⁻⁶. -4 mm -3 to -1.0×10 -4 mm -3 The value of the sixth-order aspherical coefficient A6' can range from approximately -1.0 × 10⁻⁶. -5 mm -5 Up to 3.0×10 -5 mm -5 The value of . In an embodiment, fourth-order and sixth-order aspherical coefficients can be selected to optimize the spherical aberration of the optics 120.

[0061] The region structure 160 may further include an outer transition region 164 with a second curvature. For example... Figure 2 As shown in the cross-sectional view, the outer transition region 164 can functionally extend radially from the second boundary 124 to the third boundary 126, wherein the third boundary 126 is located at a radial distance further away from the optical axis 105 than the second boundary 124. Although Figure 2The functional boundary of the outer transition region 164 is depicted as extending radially from the second radial boundary 124 to the third radial boundary 126, but it should be understood that the structure forming the outer transition region 164 technically extends radially from the optical axis 105 to the third radial boundary 126. However, the innermost region 164a of the outer transition region 164 from the optical axis 105 to the second radial boundary 124 (depicted by dashed lines) does not functionally contribute to the multilayer surface profile of the front surface 130 of the optics 120. In other words, only the outermost region 164b of the outer transition region 164 functionally contributes to the synthetic height loss 180 of the multilayer surface profile of the front surface 130. The outer transition region 164 may include a refractive surface and may be used to provide a smooth transition from the inner focal region 162 to the base structure 170.

[0062] In some embodiments, the outer transition region 164 may be excluded from the design of the optics 120. In such embodiments, it should be understood that the remaining structures (e.g., phase-shifting structure 150, inner focal region 162, and / or base structure 170) may be modified to provide a proper transition from the inner focal region 162 to the base structure 170. For example, the base structure 170 (described below) may be modified to functionally begin at the second radial boundary 124 (instead of the third radial boundary 126) and may extend radially to the outermost edge 128 of the optics. As a further example, the superposition of the outer portion 162b of the inner focal region 162 of the region structure 160 and the transition region 154 of the phase-shifting structure 150 may provide a transition from the inner focal region 162 to the base structure 170. It should be understood that these and other modifications to the optics are considered to be within the scope of this disclosure.

[0063] Figure 2 The outer transition region 164 shown can be defined by the following equation:

[0064] Equation (4)

[0065] in,

[0066] r represents the radial distance from the optical axis 105 of the optical device 120.

[0067] c2 represents the basic curvature of the outer transition region 164.

[0068] k2 represents the conic constant.

[0069] r2 represents the radial distance from the optical axis 105 to the second radial boundary 124.

[0070] r3 represents the radial distance from the optical axis 105 to the third radial boundary 126.

[0071] "A4" is the fourth-order aspherical coefficient, and

[0072] "A6" is the sixth-order aspherical coefficient.

[0073] In one embodiment, the radial distance r2 from the optical axis 105 to the second radial boundary 124 can include a value ranging from approximately 0.45 mm to 0.80 mm. In one embodiment, the value of r2 in equation (4) of the outer transition region 162 can be substantially equal to the value of r2 in equation (2a) of the trapezoidal phase shift structure 150. In yet another embodiment, there may be some degree of variation between the value of r2 in equation (4) of the outer transition region 162 and the value of r2 in equation (2a) of the trapezoidal phase shift structure 150. The radial distance r3 from the optical axis 105 to the third radial boundary 126 can include a value ranging from approximately 0.60 mm to 1.2 mm. The basic curvature c2 of the outer transition region 164 can include a value ranging from approximately 20.0 mm. -1 up to 20.5mm -1 The value of the conic constant k2 can range from approximately -100 to -30. The fourth-order aspheric coefficient A4 can include values ​​ranging from -6.5 × 10⁻⁶. -4 mm -3 to -1.0×10 -4 mm -3 The value of the sixth-order aspheric coefficient "A6" can range from approximately -1.0 × 10⁻⁶. -5 mm -5 Up to 3.0×10 -5 mm -5 The value of .

[0074] Continue to combine Figure 2 For reference Figure 1A The base structure 170 may include a third profile or structure of a multi-layered surface profile of the front surface 130 of the optical device 120. In some embodiments, the base structure 170 may be in the form of a base curvature. Figure 2 As shown in the cross-sectional view, the base structure 170 can functionally extend radially from the third radial boundary 126 to the outermost edge 128 of the optics. Although Figure 2 The functional boundary of the basic curvature or basic structure 170 (i.e., radially extending from the third radial boundary 126 to the outermost edge 128 of the optics) is depicted, but it should be understood that the basic structure 170 technically extends radially from the optical axis 105 to the outermost edge 128 of the optics 120. However, the innermost region 170a of the basic structure 170 (depicted by dashed lines, from the optical axis 105 to the third radial boundary 126) does not functionally contribute to the multilayer surface profile of the front surface 130 of the optics 120. In other words, only the outermost region 170b of the basic structure 170 functionally contributes to the synthetic height 180 of the multilayer surface profile of the front surface 130.

[0075] In an embodiment, the base structure 170 may include an aspherical surface profile having a base lens power, as understood in the art. In an embodiment, the base structure may have an optical power ranging from -15D to +50D.

[0076] Figure 2 The basic structure 170 shown can be defined by the following equation:

[0077] Equation (5)

[0078] in,

[0079] r represents the radial distance from the optical axis 105 of the optical device 120.

[0080] c represents the curvature of the basic structure at 170 degrees.

[0081] k represents the conic constant.

[0082] r3 represents the radial distance from the optical axis to the third boundary 126.

[0083] A4 is the fourth-order aspherical coefficient, and

[0084] A6 is the sixth-order aspherical coefficient.

[0085] In an embodiment, the radial distance r3 from the optical axis 105 to the third radial boundary 126 may include a value ranging from approximately 0.60 mm to 1.2 mm. The fundamental curvature c of the base structure 170 may include a value ranging from approximately 0.0152 mm. -1 Up to approximately 0.0659 mm -1 The value of the conic constant k can range from approximately -1162 to approximately -19. The fourth-order aspheric coefficient A4 can range from approximately 0.0 mm. -3 To approximately -5.3 × 10 -3 mm -3 The value of the sixth-order aspheric coefficient A6 can range from approximately 0.0 mm. -3 To approximately 1.53 × 10 -4 mm -5 The value of .

[0086] Further reference Figure 2 As mentioned above, the superposition of structures 150, 160, and 170 can produce composite multilayer surface profiles (in... Figure 2(Catalystically marked "synthetic height loss" 180). Synthetic height loss 180 may further correspond to a first region, a second region, a third region, and a fourth region 182, 184, 186, 188 defined by radial boundaries 122, 124, 126, 128, respectively. Each of the first region, second region, third region, and fourth region 182, 184, 186, 188 of synthetic height loss 180 may be generated by a composite contribution from one or more of the aforementioned structures 150, 160, 170.

[0087] For example, the first region 182 of the synthesized height loss 180 can be defined as a region extending radially from the optical axis 105 to the first radial boundary 122. In one embodiment, the first region 182 may be formed by the superposition of the inner region 152 of the phase shift structure 150 and the inner portion 162a of the inner focal region 162 of the region structure 160. In an embodiment, the first region 182 may not include contributions from the outer transition region 164 of the region structure 160 (e.g., the innermost region 164a of the outer transition region 164) or from the base structure 170 (e.g., the innermost region 170a of the base structure), because, as stated above, the innermost region 164a of the outer transition region 164 and the innermost region 170a of the base structure do not functionally contribute to the synthesized height loss 180 of the first region 182. In yet another embodiment, the first region 182 of the synthesized height loss 180 may be defined solely by the inner focal region 162, more specifically by the inner portion 162a of the inner focal region 162. In other words, the internal region 152 of the phase-shifting structure may not functionally contribute to the synthesis of height loss. The first region 182 may include a first composite aspherical profile.

[0088] The second region 184 of the synthesized height loss 180 can be defined as a region extending radially from the first radial boundary 122 to the second radial boundary 124. In an embodiment, the second region 184 can be formed by superimposing the transition region 154 of the phase shift structure 150 and the outer portion 162b of the inner focal region 162 of the region structure 160. In an embodiment, the second region 184 may not include contributions from the outer transition region 164 of the region structure 160 (e.g., the innermost region 164a of the outer transition region 164) or from the base structure 170 (e.g., the innermost region 170a of the base structure), because the innermost region 164a of the outer transition region 164 and the innermost region 170a of the base structure 170 do not functionally contribute to the synthesized height loss 180 of the second region 184. When the transition region 154 (with a single-step phase shift) is combined with the outer portion 162b of the inner focal region 162, the synthesized second region 184 can be used as a transition from the first region 182 to the third region 186. The second region 184 may include a second composite aspherical profile.

[0089] Continue to refer to Figure 2 The third region 186 of the composite height loss 180 can be defined as a region extending radially from the second radial boundary 124 to the third radial boundary 126. In one embodiment, the third region 186 can be formed by superimposing the outermost region 164b of the outer transition region 164 of the region structure 160 and the outer region 156 of the phase shift structure 150. The third region 186 (which is a combination of the outermost region 164b of the outer transition region 164 and the outer region 156) can be used as a transition from the second region 184 to the fourth region 188. In an embodiment, the third region 186 may not include contributions from the base structure 170 (e.g., the innermost region 170a of the base structure), because the innermost region 170a of the base structure does not functionally contribute to the composite height loss 180 of the third region 186. In yet another embodiment, the third region 186 may be defined solely by the outer transition region 164 of the region structure 160, more specifically by the outermost region 164b of the outer transition region 164. In other words, the outer region 156 of the phase-shifting structure may not functionally contribute to the synthesis of height loss. The third region 186 may include a third composite aspherical profile.

[0090] The fourth region 188 of the synthesized height loss 180 can be defined as a region extending radially from the third radial boundary 126 to the outermost edge 128 of the optics. In one embodiment, the fourth region 188 can be formed by superimposing the outer region 156 of the phase shift structure 150 and the base structure 170. In yet another embodiment, the fourth region 188 can be defined solely by the base structure 170. In other words, the outer region 156 of the phase shift structure 150 may not functionally contribute to the synthesized height loss. The fourth region 188 may include a fourth composite aspherical profile.

[0091] In short, by Figure 1A and Figure 2 The basic geometry of the example optical device, as defined by equations (1) to (5), is a combination of a trapezoidal phase-shifting structure and a regional refractive surface with an additional focal power effect, which together can improve intermediate vision performance and extend the depth of focus while maintaining distance vision. It should be understood that various modifications, enhancements, and adjustments can be made to the optical device 120 described herein without departing from the spirit and scope of this disclosure.

[0092] Now for reference Figures 3A to 3C It shows Figure 1A and Figure 2 The surface profile of the front surface 130 of the optical device 120 shown and defined by equations (1) to (5) is graphically represented as curves 310, 320, and 330 of the height versus the radial distance from the optical axis 105 of the optical device 120. Specifically, Figure 3A The trapezoidal phase-shift structure of the optical device 120 is depicted. Figure 2 Figure 310 shows the height loss curve of component 150. Figure 3B The regional structure of the optical device 120 is depicted. Figure 2 Figure 320 shows the unitless height loss curve of component 160. Figure 3C Figure 330 shows the height loss curve depicting the profile of the composite multilayer surface of the front surface 130 of the optical device 120. Figures 3A to 3C In all three curves, the radius is zero at 305 on the optical axis. For example... Figure 3C As shown, the height loss curve is essentially parabolic, consistent with the surface of the aspherical lens. It should be understood that... Figures 3A to 3C The curves are shown for illustrative purposes only, i.e., to show the shape of the curves, and therefore may not be drawn to scale and may not show the position of the curves according to specific data points and / or units of measurement.

[0093] Now for reference Figures 4A to 4D It shows the defocus modulation transfer function (MTF) curves of four optical devices, plots 410, 420, 430, and 440. Figure 4A The MTF curve of a single-focus IOL optical device is shown in Figure 410. Figure 4B MTF curve 420 of an optical device with a trapezoidal phase shift (TPS) structure (without regional additional focal length structure) is shown. Figure 4C MTF curve 430 of an optical device with a regional additional focal length structure (without a phase shift structure) is shown. Figure 4D It shows the basis Figure 1A and Figure 2 MTF curve 440 of the example optics 120 shown and defined by equations (1) to (5). These curves 410, 420, 430, and 440 can be compared and analyzed to further understand the improvements provided by the example optical design disclosed herein (described in curve 440). For example, as Figure 4A As shown, the optics of a single-focus IOL do not have an extended depth of focus. Next, as... Figure 4B As shown, optical devices with a trapezoidal phase-shift structure (without regional additional focal power structure) exhibit a limited depth of focus and poor MTF at defocus ranges above 0.5D (myopic side). Third, as... Figure 4C As shown, optics with a regional additional focal length structure (without a phase shift structure) exhibit bifocality, as evidenced by two distinct peaks at positive and negative focal shifts. This strong bifocality can lead to undesirable pupil-related focal shifts and / or halos. Finally, as Figure 4D As shown, based on Figure 1A and Figure 2The example optics shown and defined by equations (1) to (5) of this disclosure provide extended intermediate vision without sacrificing distance vision and without additional visual obstruction compared to monofocal IOLs. Figure 4D As further shown, the example optics further provide enhanced depth of focus extension and MTF performance in intermediate vision, for example, particularly at 1.0D to about 1.5D.

[0094] Now for reference Figure 5 It shows that based on Figure 1A and Figure 2 The simulated monocular visual acuity (VA) curves of the example optics shown in Figure 500, defined by equations (1) to (5), are illustrated. Visual acuity (VA) is a primary measure of visual function in both clinical practice and research. VA can be modeled using the intersection of the eye's modulation transfer function (MTF) and the retinal threshold function. Figure 5 In the diagram, the solid black curve 510 represents a single-focus IOL, and the multiple dashed curves 520, 530, 540, 550, and 560 represent example optics according to this disclosure. As shown in the table, each example optics is associated with a different additional focal length extension. Figure 5 As shown, each curve for example optics 520, 530, 540, 550, and 560 illustrates the depth of focus extension on a single-focus IOL 510. The depth of focus extension ranges from 0.42D in example optics 520 to a maximum depth of focus extension of 1.38D in example optics 560 (shown as 570). While there is a small trade-off in visual acuity with increasing depth of focus, it should be understood that optimal designs attempt to balance these considerations.

[0095] In use, the intraocular lens (IOL) described herein is adapted for insertion into a human eye using conventional surgical techniques modified according to the teachings herein. Typically, the natural lens is first removed, and the IOL can be folded to a compact size for insertion through an incision or opening in the capsular bag. After insertion, the IOL can be manipulated to take its proper position within the capsular bag.

[0096] A variety of technologies and materials can be used to manufacture the lenses described in this disclosure. For example, Figure 1A and Figure 1B The optical device 120 can be formed from a variety of biocompatible polymer materials. Suitable biocompatible materials include, but are not limited to, soft acrylic polymers, hydrogels, polymethacrylates, polysulfones, polystyrene, cellulose, acetate butyrate, or other biocompatible materials. By way of example, in this embodiment, the optical device 120 can be made from materials commonly referred to as… The lens loop 110 is formed from a soft acrylic polymer (a crosslinked copolymer of 2-phenylethyl acrylate and 2-phenylethyl methacrylate). The loop 110 of the lens can be formed from a suitable biocompatible material as discussed above. While in some cases the optics 120 and loop 110 of the IOL can be manufactured as a single unit, in other cases they can be formed separately or joined together using techniques known in this art.

[0097] In this document, "or" is inclusive rather than exclusive, unless otherwise expressly stated or the context otherwise indicates. Therefore, in this document, "A or B" means "A, B, or both," unless otherwise expressly stated or the context otherwise indicates. Furthermore, "and" is both joint and multiple, unless otherwise expressly stated or the context otherwise indicates. Therefore, in this document, "A and B" means "A and B, together or separately," unless otherwise expressly stated or the context otherwise indicates.

[0098] It should be understood that the various features and functions disclosed above, and other features and functions, or alternatives thereof, can be combined as desired into many other different systems or applications. It should also be understood that various alternatives, modifications, variations, or improvements not currently seen or anticipated can be subsequently made by those skilled in the art, and these alternatives, variations, and improvements are also intended to be covered by the appended claims. Those skilled in the art will understand that various changes can be made to the above embodiments without departing from the scope of the invention.

Claims

1. An ophthalmic lens, comprising: An optical device having an optical axis and a composite multilayer surface profile, the composite multilayer surface profile corresponding to the superposition of at least three profiles, the three profiles including a phase-shifting structure, a region structure, and a base structure: The regional structure has an inner focal length region and an outer transition region, the inner focal length region having a first curvature and the outer transition region having a second curvature; as well as The basic structure has a basic curvature that extends radially from the optical axis toward the outermost edge of the optical device.

2. The ophthalmic lens as described in claim 1, wherein, The phase-shift structure is characterized by an inner region, an outer region, and a transition region, wherein: The internal region extends radially from the optical axis to the first boundary; The transition region is located between the inner region and the outer region and extends radially from the first boundary to a second boundary, the second boundary being located at a radial distance further away from the optical axis than the first boundary; and The outer region extends radially from the second boundary toward the outermost edge of the optical device.

3. The ophthalmic lens as described in claim 2, wherein, The transition region is adapted such that the phase of the radiation incident thereon varies linearly over at least a portion of the radial range between the first boundary and the second boundary to produce a phase shift between the first boundary and the second boundary.

4. The ophthalmic lens as described in claim 2, wherein, The inner focal length region extends radially from the optical axis to the second boundary, and the outer transition region extends radially from the optical axis to the third boundary, the third boundary being located at a radial distance further away from the optical axis than the second boundary.

5. The ophthalmic lens as described in claim 2, wherein, The composite multilayer surface profile of the optical device is described by the following equation: WITH total =Z aux +Z zone1 +Z zone2 +Z base 。 6. The ophthalmic lens as described in claim 5, wherein, Z aux Corresponding to the phase shift structure, and described by the following equation: in, r represents the radial distance from the optical axis of the optical device. r1 represents the radial distance from the optical axis to the first boundary; r2 represents the radial distance from the optical axis to the second boundary; And among them, Δ is defined by the following relationship: in, n1 represents the refractive index of the material forming the optical device. n2 represents the refractive index of the medium surrounding the optical device. λ represents the design wavelength, and α represents a non-integer decimal.

7. The ophthalmic lens as described in claim 6, wherein, r1 includes values ​​ranging from 0.45 mm to 0.75 mm.

8. The ophthalmic lens as described in claim 6, wherein, r2 includes values ​​ranging from 0.75 mm to 1.05 mm.

9. The ophthalmic lens as described in claim 5, wherein, Z zone1 Corresponding to the internal focal length region, and described by the following equation: in, r represents the radial distance from the optical axis of the optical device. c1 represents the first curvature of the internal focal length region. k1 represents the conic constant. r2 represents the radial distance from the optical axis to the second boundary. A4' is the fourth-order aspherical coefficient, and A6' is the sixth-order aspherical coefficient.

10. The ophthalmic lens as claimed in claim 9, wherein, r2 includes values ​​ranging from 0.45 mm to 0.80 mm.

11. The ophthalmic lens as claimed in claim 5, wherein, Z zone2 Corresponding to the external transition region, and described by the following equation: in, r represents the radial distance from the optical axis of the optical device. c2 represents the second curvature of the outer transition region. k2 represents the conic constant. r2 represents the radial distance from the optical axis to the second boundary. r3 represents the radial distance from the optical axis to the third boundary. "A4" is the fourth-order aspherical coefficient, and "A6" is the sixth-order aspherical coefficient.

12. The ophthalmic lens of claim 11, wherein, r2 includes values ​​ranging from 0.45 mm to 0.80 mm.

13. The ophthalmic lens of claim 11, wherein, r3 includes values ​​ranging from 0.60 mm to 1.20 mm.

14. The ophthalmic lens as claimed in claim 5, wherein, Z base Corresponding to the fundamental curvature, and described by the following equation: Where r≥r3 in, r represents the radial distance from the optical axis of the optical device. c represents the value of the fundamental curvature. k represents the conic constant. r3 represents the radial distance from the optical axis to the third boundary. A4 is the fourth-order aspherical coefficient, and A6 is the sixth-order aspherical coefficient.

15. The ophthalmic lens as claimed in claim 4, wherein: The first region of the optical device includes a first composite aspherical profile, the first region being defined as extending radially from the optical axis to the first boundary; The second region of the optical device includes a second composite aspherical profile, the second region being defined as extending radially from the first boundary to the second boundary; The third region of the optical device includes a third composite aspherical profile, defined as extending radially from the second boundary to the third boundary; and The fourth region of the optical device includes a fourth composite aspherical profile, defined as extending from the third boundary to the outermost edge of the optical device.

16. An ophthalmic lens, comprising: An optical device having an optical axis and a composite multilayer surface profile, the composite multilayer surface profile corresponding to the superposition of at least three profiles, the three profiles including a trapezoidal phase-shifting structure, a region structure, and a base structure: The regional structure has an inner focal length region and an outer transition region, the inner focal length region having a first curvature and the outer transition region having a second curvature; as well as The basic structure has a basic curvature that extends radially from the optical axis toward the outermost edge of the optical device.

17. The ophthalmic lens of claim 16, wherein, The trapezoidal phase-shift structure is configured to mitigate the pupil-related focus shift effect caused by the enhanced depth of focus produced by the regional structure.

18. An ophthalmic lens, comprising: An optical device having an optical axis and a composite multilayer surface profile, the composite multilayer surface profile corresponding to the superposition of at least three profiles, the three profiles including a phase-shifting structure, a region structure, and a base structure: The phase-shifting structure is configured to progressively delay the wavefront to produce an extended depth of focus; The regional structure has a higher refractive power than the basic structure; as well as The basic structure has a basic curvature that extends radially from the optical axis toward the outermost edge of the optical device.

19. The ophthalmic lens of claim 18, wherein, The inner region of the phase shift structure has a substantially zero phase shift, and the outer region of the phase shift structure has a substantially zero phase shift.

20. The ophthalmic lens of claim 18, wherein, The phase shift structure has a step height of approximately -2.1 μm.

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