Use of celastrol or its derivatives in the preparation of a product for inhibiting neisseria gonorrhoeae

Tripterygium wilfordii, as a novel inhibitor of Neisseria gonorrhoeae, solves the treatment challenge of multidrug-resistant Neisseria gonorrhoeae by disrupting the bacterial cell membrane structure, achieving significant antibacterial effects and eradication of infection in vivo.

CN121337816BActive Publication Date: 2026-06-16THE FIRST AFFILIATED HOSPITAL OF NAVAL MEDICAL UNIVERSITY OF CHINESE PEOPLES LIBERATION ARMY

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
THE FIRST AFFILIATED HOSPITAL OF NAVAL MEDICAL UNIVERSITY OF CHINESE PEOPLES LIBERATION ARMY
Filing Date
2025-11-21
Publication Date
2026-06-16

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Abstract

The application provides application of tripterine or a derivative thereof in preparation of a product for inhibiting Neisseria gonorrhoeae, and relates to the technical field of biology and bacteriostasis. Specifically, the application relates to application of tripterine or a derivative thereof in (I) preparation of a Neisseria gonorrhoeae inhibitor; or (II) preparation of a medicine for preventing, relieving and / or treating Neisseria gonorrhoeae infection; a medicine for treating or preventing infection and / or complications caused by Neisseria gonorrhoeae; and a method for inhibiting or preventing growth of Neisseria gonorrhoeae.
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