Aortic valve and ascending aorta in-vitro testing and evaluating device

By designing a personalized aortic valve and ascending aorta extracorporeal testing device, combined with closed-loop pressure feedback control and high-precision flow field measurement, the problem of lack of personalized mechanical characteristic analysis in existing technologies has been solved, enabling more accurate device performance evaluation and personalized medical support.

CN121370073AActive Publication Date: 2026-01-23BEIJING INST OF TECH
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Patent Information

Application Number
CN202511823821.X
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-12-05
Publication Date
2026-01-23
Estimated Expiration
2045-12-05

AI Technical Summary

Technical Problem

Existing technologies lack personalized mechanical characteristic analysis, and in vitro testing models cannot accurately reflect the patient's internal environment, thus limiting precision diagnosis and treatment and the prediction of device effects.

Method used

Design an in vitro testing and evaluation device for the aortic valve and ascending aorta, including a chamber system, a drive system, a chamber auxiliary system, a circuit system, a control system, and a particle image velocimetry system. Create a model consistent with the patient's anatomy through reverse modeling, and combine closed-loop pressure feedback control to collect complex hemodynamic parameters in real time.

Benefits of technology

It enables personalized mechanical characteristic parameter output, reduces calculation errors, provides more accurate device performance evaluation, and supports precision diagnosis and personalized medical customization.

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Abstract

The invention provides an aortic valve and ascending aorta in-vitro testing device. The aortic valve and ascending aorta in-vitro testing device comprises a cavity system, a driving system, a loop system, a cavity auxiliary system, a control system and a particle image velocity measurement system. According to the device, a 1: 1 personalized aortic valve and ascending aorta vessel model is constructed based on a medical image of a patient, and a personalized hemodynamic environment is truly simulated through closed-loop pulsating flow circulation. Complex functional parameters such as blood flow velocity, pressure intensity, wall shear force and relative particle residence time can be rapidly and quantitatively obtained, and the limitation that traditional images only provide morphological data and CFD simulation depends on ideal assumption is overcome. Meanwhile, the method can be used for individualized in-vitro testing of the artificial aortic valve, the performance of the artificial aortic valve in a specific anatomical structure is evaluated, and the accuracy of preoperative planning, postoperative prediction and instrument research and development is remarkably improved. The device has the advantages of being high in physiological reduction degree, high in testing efficiency, high in result repeatability and the like, and is suitable for precise cardiovascular diagnosis and treatment and evaluation of implanted interventional instruments.
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