Bronchoalveolar lavage fluid collecting device for clinical medicine

By designing a multi-chamber collection device and switching mechanism in the bronchoalveolar lavage device, the problems of sample loss, confusion and contamination have been solved, achieving efficient and low-contamination sample collection, and improving diagnostic accuracy and patient safety.

CN121550520APending Publication Date: 2026-02-24YANGTZE UNIVERSITY
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Patent Information

Application Number
CN202511340977.2
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-09-19
Publication Date
2026-02-24

AI Technical Summary

Technical Problem

Existing bronchoalveolar lavage devices are prone to sample loss, confusion, contamination, and excessively long operation time when sampling from multiple sites, which affects diagnostic accuracy and patient safety.

Method used

Design a collection device with three independent chambers, equipped with a switching mechanism, and connected to the chambers via an inlet tube and a negative pressure tube to achieve separate collection of samples from different parts, reduce the frequency of changing collection bottles and the exposure of tubing, and prevent contamination.

Benefits of technology

It improves diagnostic accuracy and patient safety, reduces the risk of false positives, and decreases operation time and the occurrence of complications.

✦ Generated by Eureka AI based on patent content.

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Abstract

The bronchoalveolar lavage fluid collecting device comprises a bottle body, three independent cavities are formed in the bottle body, each cavity is provided with an outlet, the bottle body is provided with a fluid inlet pipe and a negative pressure pipe, the fluid inlet pipe and the negative pressure pipe are communicated with the three cavities through connecting pipes respectively, and the connecting pipes are communicated with the three cavities. A switching mechanism for independently controlling the opening or closing of each chamber connecting pipe is arranged; the bronchoalveolar lavage device is simple in structure and reasonable in design, samples of different parts can be collected in the bronchoalveolar lavage process through the three independent cavities, collection bottles do not need to be frequently replaced, the risks of sample loss or mixing and pollution are avoided, and the false positive occurrence rate is reduced; the switching mechanism can realize rapid switching of the collection chamber, reduce the steps of disconnecting and reconnecting the pipeline, save the operation time, reduce the risk of complications caused by too long operation time of a patient, and improve the diagnosis accuracy and the overall safety.
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Description

Technical Field

[0001] This invention relates to the field of medical device technology, specifically to a bronchoalveolar lavage fluid collection device for clinical medicine. Background Technology

[0002] Bronchoalveolar lavage (BAL) is an important technique in clinical medicine for the diagnosis and treatment of lung diseases. It involves injecting physiological saline through a bronchoscope and recovering the fluid to analyze or remove alveolar contents. Diagnostic BAL is used to collect samples to aid in the diagnosis of tuberculosis, interstitial lung disease, lung cancer, etc., involving 100-300 ml of fluid, with a recovery rate of 40%-70%. Therapeutic BAL (such as whole lung lavage) is used to remove substances from pulmonary alveolar proteinosis or pneumoconiosis, requiring the handling of several liters of fluid and is often performed under general anesthesia. The sample quality and operational efficiency of BAL directly affect diagnostic accuracy and patient safety.

[0003] The shortcomings of existing technology: In diagnostic pulmonary tuberculosis (BAL), multiple sampling sites are often required to improve diagnostic sensitivity. For example, in pulmonary tuberculosis cases, samples are typically taken from the right upper lobe (where lesions are concentrated) and the right middle lobe (where recovery rates are high) to detect *Acetobacter suis*. Traditional collection devices use a dual-tube system (negative pressure tube and lung tube) to collect samples from multiple collection bottles. However, frequent bottle changes increase operation time and can easily cause patient discomfort or hypoxia; disconnected tubing exposed to air can lead to contamination and affect detection accuracy; manually labeled sample origins can also cause confusion due to operational errors, reducing diagnostic reliability. Therefore, there is an urgent need for a simple, low-contamination, and highly accurate BAL collection device. Summary of the Invention

[0004] The purpose of this invention is to provide a bronchoalveolar lavage fluid collection device for clinical medicine, so as to solve the problems mentioned in the background art.

[0005] To achieve the above objectives, the present invention provides the following technical solution: a bronchoalveolar lavage fluid collection device for clinical medicine, comprising a bottle body, wherein the bottle body has three chambers, each chamber having an outlet, the bottle body having an inlet pipe and a negative pressure pipe, the inlet pipe and the negative pressure pipe having connecting pipes respectively connected to the three chambers, and the bottle body having a switch mechanism for individually controlling the opening or closing of the connecting pipes of different chambers.

[0006] Preferably, the switching mechanism includes: a fixed frame, disposed at the axis of the bottle body, with the inlet pipe and the negative pressure pipe symmetrically disposed on the fixed frame and located on both sides thereon, the connection points of the connecting pipe and the chamber being located at the upper end of the chamber, and a sliding portion provided at the axis of the fixed frame; four magnetic suction plates, three of which are disposed at the lower end of the connecting pipe and the other at the top of the fixed frame, and the magnetic suction plates are equidistantly spaced along the fixed frame; and a control mechanism, slidably disposed in the sliding portion and cooperating with the magnetic suction plates to control the opening and closing of the corresponding connecting pipe.

[0007] Preferably, the fixing frame has an opening, and the control mechanism includes: a first hollow slide rod, slidably disposed in the sliding portion, the first hollow slide rod having a first extension plate on its side wall, the extension plate having a first magnetic ring after passing through the opening, and the first hollow slide rod having a first movable opening on its side wall; a second hollow slide rod, slidably disposed in the first hollow slide rod, the second hollow slide rod having a second extension plate on its side wall, the second extension plate having a second magnetic ring after passing through the first movable opening and the opening, and the second hollow slide rod having a second movable opening on its side wall; and a third slide rod, slidably disposed in the second hollow slide rod, the third slide rod having a third extension plate on its side wall, the third extension plate having a third magnetic ring after passing through the second movable opening, the first movable opening, and the opening.

[0008] Preferably, the control mechanism has two opposing ends, and the two ends of the control mechanism are provided with pressing mechanisms for easy operation.

[0009] Preferably, the pressing mechanism includes: a first pressing plate symmetrically disposed at both ends of the first hollow slide rod; a second pressing plate symmetrically disposed at both ends of the second hollow slide rod; and a third pressing plate symmetrically disposed at both ends of the third hollow slide rod, wherein the first pressing plate, the second pressing plate, and the third pressing plate are arranged in an array along the circumferential direction of the first hollow slide rod.

[0010] Preferably, the first hollow slide rod has a first opening at both ends to facilitate the movement of the second pressure plate, and the second hollow slide rod and the first hollow slide rod have a second opening at both ends to facilitate the movement of the second pressure plate.

[0011] Preferably, both the second pressure plate and the third pressure plate have extensions.

[0012] Preferably, the fixing frame is provided with fixing members at both ends, and the fixing frame is fixed to the bottle body by the fixing members.

[0013] Preferably, the outlet of the chamber is provided with a flow tube, and the inlet of the flow tube is lower than the outlet.

[0014] Preferably, the side wall of the fixing frame is provided with a fixing block, and the liquid inlet pipe and the negative pressure pipe are mounted on the fixing frame through the fixing block.

[0015] Compared with the prior art, the beneficial effects of the present invention are: This invention, by dividing the bottle into three independent chambers, enables separate collection of samples from different sites during bronchoalveolar lavage, eliminating the need for frequent bottle changes. This avoids sample loss or contamination common in traditional methods and prevents contamination risks associated with tubing disconnection and air exposure during bottle changes. It also reduces the likelihood of false positives and improves diagnostic accuracy. Furthermore, the included switching mechanism allows selective switching between chambers, minimizing the need to disconnect and reconnect tubing during tube changes, saving time, and reducing the risk of complications due to prolonged procedures. This enhances overall safety and patient tolerance. Attached Figure Description

[0016] Figure 1 This is a schematic diagram of the overall structure of the present invention; Figure 2 This is a top view of the present invention; Figure 3 This is a schematic diagram of the internal structure of the present invention; Figure 4 This is a schematic diagram of the structure of the switching mechanism of the present invention when no control mechanism is installed inside; Figure 5 This is a schematic diagram of the control mechanism structure of the present invention; Figure 6 This is a schematic diagram of the end pressing mechanism of the control mechanism of the present invention.

[0017] In the diagram: 1. Bottle body; 2. Chamber; 3. Outlet; 4. Inlet pipe; 5. Negative pressure pipe; 6. Connecting pipe; 7. Switching mechanism; 701. Fixing frame; 702. Sliding part; 703. Magnetic suction plate; 8. Control mechanism; 801. First hollow slide rod; 802. First extension plate; 803. First magnetic suction ring; 804. First movable opening; 805. Second hollow slide rod; 806. Second extension plate; 807. Second magnetic suction ring; 808. Second movable opening; 809. Third slide rod; 810. Third extension plate; 811. Third magnetic suction ring; 9. Pressing mechanism; 901. First pressure plate; 902. Second pressure plate; 903. Third pressure plate; 10. First opening; 11. Second opening; 12. Extension part; 13. Fixing component; 14. Flow tube; 15. Fixing block; 16. Opening. Detailed Implementation

[0018] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0019] In the description of this invention, it should be understood that the terms "center," "longitudinal," "lateral," "length," "width," "thickness," "upper," "lower," "top," "bottom," "inner," "outer," "clockwise," and "counterclockwise," etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this invention.

[0020] In the description of this patent, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "setting" should be interpreted broadly. For example, they can refer to a fixed connection or setting, a detachable connection or setting, or an integrated connection or setting. Those skilled in the art can understand the specific meaning of the above terms in this patent according to the specific circumstances.

[0021] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of this invention, "a number" means two or more, unless otherwise explicitly specified.

[0022] Example Please see Figure 1-6 As shown, the present invention provides a technical solution for a bronchoalveolar lavage fluid collection device for clinical medicine: A bronchoalveolar lavage fluid collection device for clinical medicine includes a bottle body 1, which has three chambers 2 inside. Each chamber 2 has an outlet 3. The bottle body 1 is provided with an inlet pipe 4 and a negative pressure pipe 5. The inlet pipe 4 and the negative pressure pipe 5 are each provided with a connecting pipe 6 that is connected to the three chambers 2 respectively. The bottle body 1 is provided with a switch mechanism 7 for individually controlling the opening or closing of the connecting pipes 6 of different chambers 2.

[0023] In the following content, "top" and "bottom" are all based on the concept of "top" and "bottom". Figure 1 The direction is described for reference.

[0024] like Figure 3 and Figure 4 As shown, the switching mechanism 7 includes components such as a fixed frame 701, four magnetic plates 703, and a control mechanism 8. The fixed frame 701 is located at the center of the bottle body 1 and is arranged along the axial direction of the bottle body 1. The liquid inlet pipe 4 and the negative pressure pipe 5 are symmetrically arranged on the fixed frame 701 and located on both sides of it. The connection points of the connecting pipe 6 and the chamber 2 are all located at the upper end of the chamber 2. A sliding part 702 is provided at the center of the fixed frame 701. Three magnetic plates 703 are located at the lower end of the connecting pipe 6, and one is located at the top of the fixed frame 701, inside the top fixing member 13 of the fixed frame 701. The magnetic plates 703 are arranged at equal intervals along the fixed frame 701. The control mechanism 8 is slidably arranged in the sliding part 702 and cooperates with the magnetic plates 703 to control the opening and closing of the corresponding connecting pipe 6.

[0025] In this embodiment, the sliding portion 702 is as follows: Figure 4 As shown, it mainly consists of a sliding key along the overall height direction of the fixed frame 701, to facilitate the sliding of the control mechanism 8.

[0026] like Figure 4-5 As shown, the fixed frame 701 has an opening 16, and the control mechanism 8 includes components such as a first hollow slide rod 801, a second hollow slide rod 805, and a third slide rod 809. The first hollow slide rod 801 is slidably disposed in the sliding part 702. A first extension plate 802 is provided on the side wall of the first hollow slide rod 801. After the extension plate passes through the opening 16, a first magnetic ring 803 is provided. A first movable opening 804 is opened on the side wall of the first hollow slide rod 801. The second hollow slide rod 805 is slidably disposed in the first hollow slide rod 801. The second hollow slide rod 805 has a second extension plate 806 on its side wall. The second extension plate 806 passes through the first movable opening 804 and the opening 16 and is provided with a second magnetic ring 807. The second hollow slide rod 805 has a second movable opening 808 on its side wall. The third slide rod 809 is slidably disposed in the second hollow slide rod 805. The third slide rod 809 has a third extension plate 810 on its side wall. The third extension plate 810 passes through the second movable opening 808, the first movable opening 804 and the opening 16 and is provided with a third magnetic ring 811.

[0027] In this embodiment, the first hollow slide bar 801, the second hollow slide bar 805, and the third slide bar 809 all employ the same sliding structure. Specifically, each slide bar interacts with a sliding groove via an internally provided sliding key, achieving a linear sliding connection along the height of the bar while preventing relative rotation between the slide bars. Of course, this structure can be implemented in various ways; the method described in this embodiment is only one example and is not limited thereto.

[0028] In addition, it should be noted that the sliding height of each slider is limited, and their sliding distance is equal and limited to the range between the corresponding magnetic plates 703. That is, the sliding stroke of each slider is the height range of the magnetic plate 703 where its fixedly connected magnetic ring is located.

[0029] The control mechanism 8 has two opposite ends, and the two ends of the control mechanism 8 are provided with pressing mechanisms 9 for easy operation.

[0030] like Figure 5 As shown, the pressing mechanism 9 includes: a first pressing plate 901, a second pressing plate 902, and a third pressing plate 903; the first pressing plate 901 is symmetrically arranged at both ends of the first hollow slide rod 801; the second pressing plate 902 is symmetrically arranged at both ends of the second hollow slide rod 805; the third pressing plate 903 is symmetrically arranged at both ends of the third hollow slide rod, and the first pressing plate 901, the second pressing plate 902, and the third pressing plate 903 are arranged in an array along the circumferential direction of the first hollow slide rod 801; this design can provide a larger operating area, making it easier for medical staff to operate.

[0031] In practice, the outer walls of the different chambers 2 of the bottle body 1 can be made of transparent plastic of different colors. The first pressure plate 901, the second pressure plate 902, and the third pressure plate 903 can be set with corresponding colors to facilitate identification and operation by medical staff.

[0032] like Figure 5 As shown, the first hollow slide bar 801 has first openings 10 at both ends to facilitate the movement of the second pressure plate 902, and the second hollow slide bar 805 and the first hollow slide bar 801 have second openings 11 at both ends to facilitate the movement of the second pressure plate 902. This structural design can reduce the length of the first hollow slide bar 801 and the second hollow slide bar 805 while ensuring functionality, thereby making the height distribution of the three slide bars more balanced and improving the overall aesthetics of the structure.

[0033] like Figure 5 and Figure 6 As shown, both the second pressure plate 902 and the third pressure plate 903 have an extension 12, the width and height of which are designed to match the corresponding first opening 10 and second opening 11. This design allows the extension 12 to pass smoothly through the openings while reducing the size of the first opening 10 and the second opening 11, thereby improving the structural strength of the first hollow slide bar 801 and the second hollow slide bar 805.

[0034] It should be noted that the height of the first opening 10 and the second opening 11 is slightly higher than the range of the movement height of each magnetic ring, so as to ensure that each magnetic ring is not interfered with or restricted by the corresponding pressure plate during the adjustment process.

[0035] like Figure 4As shown, both ends of the fixing frame 701 are equipped with fixing members 13 for securely mounting the fixing frame 701 onto the bottle body 1. The top fixing member 13 includes a top plate and a ring plate arranged circumferentially along the top plate. The top plate has fixing holes to allow the liquid inlet pipe 4 and the negative pressure pipe 5 to pass through, and to fix the passing parts of the two pipes. The top plate is connected to the top of the ring plate, and the bottom of the ring plate is fixed to the bottle body 1. The bottom fixing member 13 includes a bottom plate, the middle of which is connected to the fixing frame 701, and its outer edge is fixedly connected to the bottle body 1, thereby achieving stable support for the upper and lower ends of the fixing frame 701.

[0036] A flow tube 14 is connected to the outlet 3 of chamber 2. The inlet of the flow tube 14 is lower than the outlet 3, and a plug is provided at the outlet 3 to prevent the rinsing fluid from overflowing and being exposed to air during the collection process. In addition, the height difference design between the inlet and outlet of the flow tube 14 can further prevent direct leakage of liquid in the event of plug failure.

[0037] The side wall of the fixing frame 701 is provided with a fixing block 15. The liquid inlet pipe 4 and the negative pressure pipe 5 are mounted on the fixing frame 701 through the fixing block 15. This structural design can keep the liquid inlet pipe 4 and the negative pressure pipe 5 in a straight state at all times, and avoid affecting the smoothness of the pipeline due to squeezing during the switching of chamber 2, thereby ensuring the stability of the collection effect.

[0038] In addition, protective sleeves may be optionally fitted to the outer sides of each magnetic plate 703 and its corresponding magnetic ring. These sleeves may be flexible components, including but not limited to rubber pads, to reduce direct hard contact between the two during operation, thereby preventing damage to the device structure. Furthermore, the magnetic attraction force between the magnetic plate 703 and each magnetic ring can be adjusted according to actual usage requirements to ensure optimal clamping and release effects under different working conditions.

[0039] In this embodiment, The working principle of this invention is as follows: During use, the chambers 2 inside the bottle 1 are put into use in sequence from bottom to top, and the operation must be completed by a single person, while keeping the device in a horizontal position.

[0040] During the initial collection, the operator first pushes up the first pressure plate 901 and presses down the second pressure plate 902 and the third pressure plate 903, so that the connecting pipes 6 of the two chambers 2 located at the top and middle are respectively pressed closed by the corresponding magnetic suction plates 703, the first magnetic suction ring 803 and the second magnetic suction ring 807 through mutual attraction. At this time, negative pressure is provided through the negative pressure pipe 5, and the irrigation fluid enters through the inlet pipe 4 and flows into the bottom chamber 2 through the outlet of the bottom connecting pipe 6.

[0041] During the second collection, the operator pushes up the second pressure plate 902 and presses down the first pressure plate 901 to close the connecting pipes 6 of the two chambers 2 above and below. Then, the irrigation fluid is introduced into the intermediate chamber 2 using the same method as the first collection.

[0042] During the third collection, the operator pushes up the third pressure plate 903 and presses down the second pressure plate 902, closing the connecting pipes 6 of the two chambers 2 in the middle and lower sections. The irrigation fluid is then introduced into the upper chamber 2 in the same manner. Throughout the operation, the operator can quickly identify the target pressure plate by its color, thus achieving efficient operation.

[0043] When removing the irrigation fluid, first remove the plug at the outlet 3 of the corresponding chamber 2 and pour out the liquid; when cleaning, remove the plug and inject the cleaning fluid into the chamber 2 simultaneously through the inlet pipe 4 and the negative pressure pipe 5. After cleaning, the cleaning fluid can be discharged.

[0044] The foregoing has shown and described the basic principles, main features, and advantages of the present invention. Those skilled in the art should understand that the present invention is not limited to the above embodiments. The embodiments and descriptions in the specification are merely preferred examples and are not intended to limit the invention. Various changes and modifications can be made to the invention without departing from its spirit and scope, and all such changes and modifications fall within the scope of the present invention as claimed. The scope of protection of the present invention is defined by the appended claims and their equivalents.

Claims

1. A bronchoalveolar lavage fluid collection device for clinical medicine, characterized in that: The device includes a bottle body with three chambers, each chamber having an outlet. The bottle body is equipped with an inlet pipe and a negative pressure pipe, and each of the inlet pipe and the negative pressure pipe is equipped with a connecting pipe that is connected to the three chambers respectively. The bottle body is equipped with a switch mechanism for individually controlling the opening or closing of the connecting pipes of different chambers.

2. The bronchoalveolar lavage fluid collection device for clinical medicine according to claim 1, characterized in that: The switching mechanism includes: a fixed frame, located at the axis of the bottle body, with the inlet pipe and the negative pressure pipe symmetrically arranged on the fixed frame and located on both sides thereon, and the connection points of the connecting pipe and the chamber located at the upper end of the chamber, and a sliding part provided at the axis of the fixed frame; four magnetic suction plates, three of which are located at the lower end of the connecting pipe and the other at the top of the fixed frame, and the magnetic suction plates are equidistantly arranged along the fixed frame; and a control mechanism, slidably disposed in the sliding part and cooperating with the magnetic suction plates to control the opening and closing of the corresponding connecting pipe.

3. The bronchoalveolar lavage fluid collection device for clinical medicine according to claim 2, characterized in that: The fixed frame has an opening, and the control mechanism includes: a first hollow slide rod, slidably disposed in the sliding portion, with a first extension plate on the side wall of the first hollow slide rod, and a first magnetic ring after the extension plate passes through the opening; a first movable opening is provided on the side wall of the first hollow slide rod; a second hollow slide rod, slidably disposed in the first hollow slide rod, with a second extension plate on the side wall of the second hollow slide rod, and a second magnetic ring after the second extension plate passes through the first movable opening and the opening; a second movable opening is provided on the side wall of the second hollow slide rod; and a third slide rod, slidably disposed in the second hollow slide rod, with a third extension plate on the side wall of the third slide rod, and a third magnetic ring after the third extension plate passes through the second movable opening, the first movable opening, and the opening.

4. The bronchoalveolar lavage fluid collection device for clinical medicine according to claim 3, characterized in that: The control mechanism has two opposing ends, and both ends of the control mechanism are provided with pressing mechanisms for easy operation.

5. A bronchoalveolar lavage fluid collection device for clinical use according to claim 4, characterized in that: The pressing mechanism includes: a first pressing plate symmetrically disposed at both ends of the first hollow slide rod; a second pressing plate symmetrically disposed at both ends of the second hollow slide rod; and a third pressing plate symmetrically disposed at both ends of the third hollow slide rod, wherein the first pressing plate, the second pressing plate, and the third pressing plate are arranged in an array along the circumferential direction of the first hollow slide rod.

6. The bronchoalveolar lavage fluid collection device for clinical use according to claim 5, characterized in that: The first hollow slide rod has a first opening at both ends to facilitate the movement of the second pressure plate, and the second hollow slide rod and the first hollow slide rod have a second opening at both ends to facilitate the movement of the second pressure plate.

7. A bronchoalveolar lavage fluid collection device for clinical use according to claim 6, characterized in that: Both the second pressure plate and the third pressure plate have extensions.

8. A bronchoalveolar lavage fluid collection device for clinical use according to claim 2, characterized in that: The fixing frame is provided with fixing members at both ends, and the fixing frame is fixed to the bottle body by the fixing members.

9. A bronchoalveolar lavage fluid collection device for clinical medicine according to claim 1, characterized in that: The chamber is provided with a flow tube at its outlet, and the inlet of the flow tube is lower than the outlet.

10. A bronchoalveolar lavage fluid collection device for clinical medicine according to claim 2, characterized in that: The side wall of the fixed frame is provided with a fixing block, and the liquid inlet pipe and the negative pressure pipe are mounted on the fixed frame through the fixing block.